Clinical trials: sponsored by University Hospital, Angers
Carbon Monoxide Intoxication
Evaluation of CO Intoxication Rate, by CAPillary HbCO
The main goal of COCAP is to compare COHb (carboxyhemoglobin) levels measured from venous or arterial samples with those measured from capillary samples in patients suspected of Carbon Monoxide intoxication.Patient participation…
- Trial name
- COCAP (NCT06641752)
- Testing
- Blood drop sampling
- Where
- 2 sites in France
- Volunteers
- 29 people
- Sponsor
- Nantes University Hospital
Digestive Emergency, New Pathway
Effectiveness of the RAUC Pathway in Reducing Unscheduled Hospitalizations After Emergency Digestive Surgery
The number of emergencies's visits (22 million visits in 2019 in France), the organization of emergencies and the sustainability of the current health system are threatened.
- Conditions
- Digestive Emergency, New Pathway, Connected Health
- Trial name
- RAUCAMIENS (NCT06769438)
- Testing
- ERAS, DEEPSEN, RDS
- Where
- 6 sites in France
- Volunteers
- 3,048 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Heterozygous Familial Hypercholesterolemia
Assessment of the Prevalence of Steatotic Liver Disease Associated With Metabolic Dysfunction in Patients With Heterozygous Familial Hypercholesterolemia
The main goal of the STEATO-FH study is to determine the prevalence of liver steatosis within the Heterozygous Familial Hypercholesterolemia patient population.
- Trial name
- STEATO-FH (NCT06634160)
- Testing
- Fibroscan, Sample collection
- Where
- 3 sites in France
- Volunteers
- 200 people
- Sponsor
- Nantes University Hospital
Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic)
Post Operative Pain and Vagal Stimulation
Anorectal surgery is a type of surgery that can cause anal pain, particularly in the context of hemorrhoid surgery or anal fissure surgery. Generally, the period of discomfort related to the pain lasts about two weeks.
- Conditions
- Rectal Surgery, Pain (Visceral, Somatic, or Neuropathic), Vagal Nerve Stimulation
- Trial name
- VAGANAL (NCT07659314)
- Testing
- Experimental arm, Control arm
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Myeloproliferative Neoplasm, Polycythemia Vera
Functional and Phenotypic Characterization of Monocytes in Myeloproliferative Syndromes
Prospective study for functional and phenotypic characterization of monocytes in philadelphia-negative myeloproliferative neoplasms
- Conditions
- Myeloproliferative Neoplasm, Polycythemia Vera, Essential Thrombocythemia, Primary Myelofibrosis
- Trial name
- PHEMOP (NCT06361641)
- Testing
- Monocytes signatures in myeloproliferative neoplasms at diagnosis
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Angers
Mycobacterium; Xenopi, Lung Diseases
Amikacin Liposome Inhalation Suspension for Treatment of Mycobacterium Xenopi Pulmonary Infection
Treatment of Mycobacterium xenopi (MX) lung disease is not-well- tolerated and concerned a growing number of patients, especially with chronic pulmonary diseases or immunosuppression.
- Trial name
- AKAPI (NCT06585020)
- Testing
- Arikayce, standard treatment
- Where
- France
- Volunteers
- 190 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Cerebral Palsy (CP)
Effects and Feasibility of a HABIT-ILE and a Home Program on the Bimanual Performance of Children With Cerebral Palsy
This single arm double baseline study explored the efficacy and feasibility of the PARTNER program (30h HABIT-ILE + 10h home program) on the functional changes and families' resources of 14 children with unilateral CP aged 24 to…
- Trial name
- FACT (NCT07889622)
- Testing
- Behavioral
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Fondation Ildys
Acid Sphingomyelinase Deficiency (ASMD), Niemann Pick Disease
National Multicentre Study of the Natural History of Acid Sphingo-myelinase Deficiency in Adults and Children
The goal of this study is to describe the natural history of ASMD in adult and paediatric patients with or without specific treatment in order to assess the impact of the disease on their daily lives and quality of life.
- Trial name
- FASMD (NCT06985212)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Wladimir MAUHIN, Dr
Burnout
Study of Psychosocial and Contextual Determinants of General Practitioners' Management of Burnout
Burnout is a major public and occupational health issue. Despite accumulated knowledge to date on the determinants of burnout and its treatment, shortcomings when providing support against this complex phenomenon have been found.
- Trial name
- BOPEC-MG (NCT06811181)
- Where
- France
- Volunteers
- 410 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Pain Management
Hypnosis Antalgia Emergency Stitching
Pain is one of the most common reasons patients seek care in emergency departments. Managing pain effectively is an important part of emergency care because it can improve patients' comfort and overall experience.
- Trial name
- HYPNAUS (NCT07872891)
- Testing
- hypnotic guidance
- Volunteers
- 134 people
- Sponsor
- University Hospital, Angers
Bipolar Disorder (BD)
BAROMETRE : Study on the Prognosis and Course of Individuals With Bipolar Spectrum Disorder
Bipolar disorder (BD) is often diagnosed 5 to 10 years after first symptoms, worsening prognosis. "Bipolar At-Risk" (BAR) criteria have been developed to identify people who may be in an early, prodromal stage of BD, but their…
- Trial name
- BAROMETRE (NCT07872878)
- Testing
- Structured clinical follow-up and psychometric assessment
- Where
- 3 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Obstructive Sleep Apnea
Follow-up of Apneic Patients by Visio-consultation
Prospective multicenter open-label randomized clinical trial comparing videoconsultation to a face-to-face consultation during the follow-up of apneic patients treated by continuous positive pressure (CPAP) .
- Trial name
- VISIOSAS (NCT04547543)
- Testing
- Videoconsultation
- Where
- France
- Volunteers
- 250 people
- Sponsor
- University Hospital, Grenoble
Thoraco-brachial Outlet Syndrome, ADAP-shoulder Scale
PETRA: Pictorial Assessment of Task Occurrence and Upper Limb Avoidance Behaviors
The clinical evaluation of patients suspected of having thoracic brachial outlet syndrome (TBS) is not standardized, as it may be for the lower limbs.
- Conditions
- Thoraco-brachial Outlet Syndrome, ADAP-shoulder Scale, PETRA
- Trial name
- PETRA (NCT07031791)
- Testing
- PETRA questionnaire
- Where
- France
- Volunteers
- 230 people
- Sponsor
- University Hospital, Angers
Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection
CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia
To assess the efficacy of administrating daily caspofungin aerosols versus placebo for seven days, in adjunction of conventional systemic antifungal therapy during curative treatment of Pneumocystis pneumonia, on the clinical…
- Conditions
- Pneumocystis Pneumonia, Pneumocystis Jirovecii Infection, Pneumocystis Infections
- Trial name
- CaspoNEB (NCT06892951)
- Testing
- Caspofungin Acetate 50 MG, Physiologic saline
- Where
- 3 sites in France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Tours
Severe Asthma
Educational Needs of Patients With Severe Asthma on Targeted Immunotherapies
Severe asthma is a debilitating disease that affects every aspect of patients' lives: daily life, work, social life, family life, and marital life.
- Trial name
- BASIC (NCT07856407)
- Testing
- Initial assesment interwiew, Intake Interview with the Patient
- Volunteers
- 20 people
- Sponsor
- University Hospital, Angers
Craniopharyngioma, Child
SEMAFORCRANIO : Multicenter, Double-blind, Parallel, Randomized Controlled Trial of the Efficacy of Semaglutide in Hypothalamic Obesity Secondary to Craniopharyngioma in Children Aged 12 to 17 Years
Craniopharyngioma (CP) is a rare embryonic brain tumor of the sellar and parasellar region. Despite its benign histologic characteristics, it is locally aggressive and may cause severe morbidity from invasion into adjacent…
- Trial name
- SEMAFORCRANIO (NCT07845994)
- Testing
- Semaglutide (Wegovy) weekly injection
- Where
- 17 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Angers
Delirium in the Intensive Care Unit
Impact on Delirium of the Use of DEXmedetomidine as First-line Sedation in PEDIAtric Intensive Care
The goal of this clinical trial is to learn if dexmedetomidine can reduce delirium in critically ill children, needing mechanical ventilation for more than 12 hours.
- Trial name
- PEDIADEX (NCT07542990)
- Testing
- Dexmedetomidine, Midazolam
- Where
- 7 sites in France
- Volunteers
- 266 people
- Sponsor
- University Hospital, Tours
Medical Education, Clinical Competence
Emergency Structured Clinical Examination Training bOX
This study assessed whether a training toolbox called ECOX could help medical students prepare for their objective structured clinical examination (OSCE) during an emergency medicine clerkship.
- Conditions
- Medical Education, Clinical Competence, Examination-Related Anxiety
- Trial name
- ECOX (NCT06124430)
- Testing
- ECOX workplace-based training toolbox
- Where
- France
- Volunteers
- 310 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Hindfoot Surgery, Analgesia
Postoperative Analgesia Using a Perineural Catheter Versus a Single Nerve Block in Rearfoot Surgery
Postoperative pain following hindfoot surgery is often severe and can persist for several days. It frequently leads to the use of systemic analgesics, particularly opioids, whose adverse effects are well known.
- Conditions
- Hindfoot Surgery, Analgesia, Perineural Catheter
- Trial name
- CATHORNOT (NCT07638514)
- Testing
- Phone contact, perineural catheter, Regional Anesthesia
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Angers
Gerontology, Cognitive Ability General
EFFET - Study of Executive Functions Regarding the Usability and User Experience of Assistive Technologies Among the Elderly
Population aging increases the strain on healthcare systems and highlights the value of gerontechnologies in promoting the autonomy and home-based living of older adults.
- Conditions
- Gerontology, Cognitive Ability General, Technology Use
- Trial name
- EFFET (NCT07834775)
- Testing
- high executive load task, low executive load task
- Where
- 3 sites in France
- Volunteers
- 70 people
- Sponsor
- University Hospital, Angers