Clinical trials: sponsored by University of Pittsburgh
Multiple Ground Glass Opacities (GGOs)
A Registry for Patients With Multifocal Ground Glass Opacities (GGOs)
The purpose of this registry study is to actively monitor people with GGOs and collect information about them, so that investigators can learn more about these lesions and about the risk of developing lung cancer in study…
- Trial name
- NCT03802981
- Where
- 32 sites in United States, Canada
- Volunteers
- 338 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Self-Management, Quality of Life
Efficacy of a Self-advocacy Serious Game Intervention
Individuals with cancer must overcome multiple, ongoing challenges ("self-advocate") related to their cancer experience to receive patient-centered care.
- Trial name
- NCT04813276
- Testing
- Strong Together serious game, Enhanced Care as Usual
- Where
- United States
- Volunteers
- 344 people
- Sponsor
- University of Pittsburgh
Schizophrenia Disorder, Schizoaffective Disorder
Incentives and Long-Acting Injectable Adherence After Involuntary Hospitalization
This study is a randomized controlled trial evaluating the impact of financial incentives on medication adherence among individuals with schizophrenia, schizoaffective disorder, or bipolar disorder and/or co-occurring substance…
- Conditions
- Schizophrenia Disorder, Schizoaffective Disorder, Bipolar Disorder (BD), Substance Use Disorder (SUD)
- Trial name
- NCT07130500
- Testing
- Financial incentives for adherence to long-acting injectable medication, Standard of care with monthly surveys
- Where
- 6 sites in United States
- Volunteers
- 1,000 people
- Sponsor
- Stanford University
ADHD, Autism Spectrum Disorder
AWARE: Management of ADHD in Autism Spectrum Disorder
This study is a pragmatic clinical trial examining the comparative effectiveness of two stimulant medications (methylphenidate and amphetamine) in the treatment of ADHD in children and adolescents with autism.
- Trial name
- NCT05916339
- Testing
- Randomization to either Amphetamine (AMP) class of stimulant medication or Methylphenidate (MPH) class of stimulant medication, Randomization to either Alpha 2 agonist class of medication or alternate class of stimulant.
- Where
- 13 sites in United States, Canada
- Volunteers
- 500 people
- Sponsor
- Daniel Coury
Penis/Surgery, Penis/Injuries
Autologous Fat Grafting Beneath Penile Split Thickness Skin Graft Placement During Penile Reconstruction
The goal of this randomized interventional clinical trial is to learn if placement of a thin layer of fatty tissue (fat graft) beneath a split-thickness skin graft on the surface of the penis improved outcomes of surgery in men…
- Conditions
- Penis/Surgery, Penis/Injuries, Penile Skin, Adult-Acquired Buried Penis
- Trial name
- NCT07316491
- Testing
- Autologous fat grafting, Genitourinary Reconstruction with Split-Thickness Skin Grafting
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Pittsburgh
Fibromyalgia (FM)
Feasibility and Effects of Noninvasive Brain Stimulation on Pain Perception in People With Fibromyalgia
The goal of this interventional study is to learn whether noninvasive brain stimulation (NIBS) will have an effect on pain perception in people with fibromyalgia.
- Trial name
- NCT07644221
- Testing
- Primary Motor Cortex Stimulation, Occipital Lobe Stimulation
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Pulkit Grover
Lateral Epicondylitis
Comparing Surgical and Nonsurgical Outcomes of Tennis Elbow
Tennis elbow is a condition that causes pain on the outside of the elbow, typically caused by motions involving straightening of the arm.
- Trial name
- NCT07885280
- Testing
- Conservative Arm, Surgical
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- University of Pittsburgh
Pregnancy, Postpartum Period
Impact of Collaborative Care for Pregnant Women With Opioid Use Disorder in Low-Resource Obstetric Settings
The investigators seek to adapt a collaborative care model (CCM) for community-based, low-resource obstetric settings and to test the effects of this adapted CCM on health outcomes among Pregnant, postpartum, and parenting person…
- Conditions
- Pregnancy, Postpartum Period, Opioid Use Disorder
- Trial name
- NEST (NCT06956352)
- Testing
- Usual Care, Adapted Collaborative Care Model (CCM)
- Where
- United States
- Volunteers
- 1,350 people
- Sponsor
- University of Pittsburgh
HIV Prevention, Substance Use
mHealth Service Linkage for Young Adults Impacted by the Criminal Legal System
This study is designed to test Project LYNX, a program designed to help young adults (ages 18-29) with recent criminal legal system involvement can find and get connected to substance use and HIV-prevention services in the…
- Trial name
- LYNX (NCT07599722)
- Testing
- LYNX, Standard of Care
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Cubital Tunnel Syndrome
Comparing Surgical and Nonsurgical Outcomes of Cubital Tunnel Syndrome
Cubital tunnel syndrome is a condition that occurs when the ulnar nerve, which runs along the inside of the elbow, becomes irritated or compressed. It can cause pain, numbness, tingling, or weakness in the hand and arm.
- Trial name
- NCT07862543
- Testing
- Cubital tunnel release, Conservative Arm
- Where
- 7 sites in United States
- Volunteers
- 220 people
- Sponsor
- University of Pittsburgh
Family Caregivers, Children With Medical Complexity (CMC)
Pilot Trial of a Meaning And Problem-Solving (MAPS) Intervention for Family Caregivers of Children With Medical Complexity
This study aims to evaluate a new program specifically developed to better support parents and family caregivers of children with complex health needs. The name of this program is MAPS (Meaning and Problem Solving).
- Trial name
- NCT07876206
- Testing
- MAPS (Meaning And Problem Solving), Usual Psychosocial Care
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Pittsburgh
Feasibility, Diet, Healthy
Super Chef - an Online Program Promoting the Mediterranean Dietary Pattern to Lower Income Families
Given the limited effectiveness of single food group-targeted interventions to enhance child nutrition, a key component of current and future health, innovative approaches are needed.
- Trial name
- NCT05863559
- Testing
- Super Chef: Family Fun in the Kitchen!
- Where
- United States
- Volunteers
- 116 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Gestational Diabetes, Pregnancy, High Risk
Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
- Conditions
- Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
- Trial name
- iGDM (NCT05124808)
- Testing
- Intensive glycemic targets, Standard glycemic targets
- Where
- 5 sites in United States
- Volunteers
- 828 people
- Sponsor
- Indiana University
Acute Pancreatitis
iMmune SignAtures and Clinical outComes in AP
The MoSAIC study is a prospective, observational study designed to develop an early prediction tool for severe acute pancreatitis (SAP) and define a distinct immunologic profile compared to moderate acute pancreatitis (MAP).
- Trial name
- MoSAIC (NCT05878236)
- Testing
- CyTOF Analysis
- Where
- 5 sites in United States
- Volunteers
- 198 people
- Sponsor
- Ohio State University
Sexual Violence, Drinking Heavy
Centering Gender Affirming Resources in Higher Education
Centering gender Affirming Resources in higher Education (CARE) project is nested within the parent study "Reducing Alcohol Involved Sexual violence in higher Education" (RAISE; R01 AA023260; NCT05185440).
- Trial name
- CARE (NCT06390332)
- Testing
- Giving Information for Trauma Support and Safety (GIFTSS) Training, Centering gender Affirming Resources in higher Education (CARE) Learning Modules
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Spina Bifida, Cerebral Palsy
The Impact of Community-based Wellness Programs on The Triple Aim
People with disabilities experience a staggering incidence of secondary conditions that can result in death or negatively impact their health, participation in the community, and quality of life.
- Conditions
- Spina Bifida, Cerebral Palsy, Spinal Cord Injury, Traumatic Brain Injury
- Trial name
- NCT02938130
- Testing
- Wellness Programs
- Where
- United States
- Volunteers
- 119 people
- Sponsor
- University of Pittsburgh
Smoking Cessation, Pregnancy
Baby Steps III: Testing a Clinician and Patient Intervention to Promote Smoking Cessation Among Pregnant Women
The investigators propose to conduct a combined intervention that pairs SMS smoking cessation messages for patients with individualized training for OB clinicians to improve quit rates among pregnant smoking.
- Conditions
- Smoking Cessation, Pregnancy, Communication Research
- Trial name
- NCT04985903
- Testing
- Clinician Communication Intervention, 5A's lecture
- Where
- United States
- Volunteers
- 414 people, healthy volunteers welcome
- Sponsor
- Duke University
Parkinson Disease, Prodromal Stage
Slow-SPEED: Slowing Parkinson's Early Through Exercise Dosage
The goal of this clinical trial is two-fold. First to investigate the feasibility of whether a remotely administered smartphone app can increase the volume and intensity of physical activity in daily life in individuals with a…
- Conditions
- Parkinson Disease, Prodromal Stage, Neurodegenerative Diseases, Basal Ganglia Diseases
- Trial name
- Slow-SPEED (NCT06993142)
- Testing
- Increase of physical activity volume and intensity with the use of a motivational smartphone application
- Where
- 2 sites in United States, Netherlands
- Volunteers
- 600 people
- Sponsor
- Radboud University Medical Center
Cancer, Quality of Life
The PRISM Intervention: a Multi-site Randomized Controlled Trial for Adolescents and Young Adults With Advanced Cancer
Multi-Site Randomized Controlled Trial testing the efficacy of the Promoting Resilience in Stress Management (PRISM) intervention among Adolescents and Young Adults with Advanced Cancer
- Conditions
- Cancer, Quality of Life, Anxiety, Depression
- Trial name
- PRISM-AC (NCT03668223)
- Testing
- Promoting Resilience in Stress Management (PRISM)
- Where
- 5 sites in United States
- Volunteers
- 269 people
- Sponsor
- Dana-Farber Cancer Institute
Vasectomy, Contraception
"Vasectomy: Right for Me?" Decision Support Tool
The goal of this trial is to learn if a web-based decision aid designed to provide evidence-based information about vasectomy and other birth control options helps improve users' decision-making about birth control.
- Conditions
- Vasectomy, Contraception, Contraception Behavior, Reproductive Behavior
- Trial name
- NCT07451067
- Testing
- "Vasectomy: Right for Me?" decision aid
- Where
- 2 sites in United States
- Volunteers
- 750 people
- Sponsor
- University of Pittsburgh