Clinical trials: sponsored by University of Thessaly
Acute Respiratory Distress Syndrome (ARDS)
Early Switch in Moderate ARDS
The optimal timing for transition from controlled to assisted mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) remains uncertain.
- Trial name
- SWITCH-ARDS (NCT07907276)
- Testing
- Protocolized Transition From Controlled to Assisted Mechanical Ventilation
- Volunteers
- 30 people
- Sponsor
- University of Thessaly
Chronic Musculoskeletal Pain
Effectiveness of Communication-Focused Pain Neuroscience Education in Chronic Musculoskeletal Pain
This randomized controlled trial aims to evaluate the effectiveness of the "Algo(S)Therapy" Pain Neuroscience Education (PNE) program in patients with chronic musculoskeletal pain.
- Trial name
- NCT07001449
- Testing
- Pain Neuroscience Education with Communication Training, Pain Neuroscience Education without Communication Training, Usual Physiotherapy Treatment
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- University of Thessaly
Arthroscopic Rotator Cuff Repair (ARCR), Postoperative Pain
Tapentadol vs Tramadol in Arthroscopic Rotator Cuff Repair
Compare the effectiveness of tapentadol and tramadol as part of a multimodal analgesia treatment for Arthroscopic Rotator Cuff Repair Surgery.
- Conditions
- Arthroscopic Rotator Cuff Repair (ARCR), Postoperative Pain, Chronic Pain
- Trial name
- NCT07779473
- Testing
- Tramadol, Tapentadol
- Where
- Greece
- Volunteers
- 64 people
- Sponsor
- University of Thessaly
Pregabalin on Catheter Related Bladder Discomfort
Effect of Pregabalin Administration on Catheter- Related Bladder Discomfort in Urological Surgical Operations
The aim of this study is to assess the effect of pregabalin administration on catheter-related bladder discomfort (CRBD). The study group includes patients that are about to be subjected to urological operations because of the…
- Trial name
- NCT03229668
- Testing
- Pregabalin Oral Capsule [Lyrica] 75mg, Pregabalin Oral Capsule [Lyrica] 150 mg
- Where
- 2 sites in Greece
- Volunteers
- 78 people
- Sponsor
- Saint Savvas Anticancer Hospital
Athletic Performance
Sideritis Supplementation and Performance
The purpose of this study is to examine the effect of sideritis consumption on physiological and performance indicators in adult subjects and compare it with the control trial.
- Trial name
- NCT07555288
- Testing
- 950 mg of Sideritis Scardica (SidTea+) extract one hour pre-exercise
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Ventilator Associated Pneumonia
Nebulised Colistimethate Sodium to Prevent Pediatric Ventilator-associated Pneumonia
The goal of this clinical trial is to learn if nebulized colistimethate sodium can prevent pneumonia in ventilated children. The main question it aims to answer is: Does nebulized colistimethate sodium lower the number of times…
- Trial name
- ColiPed (NCT06488794)
- Testing
- colistimethate sodium, 0.9% Saline
- Volunteers
- 400 people
- Sponsor
- University Hospital Fattouma Bourguiba
Fibromyalgia
Melatonin and Immunonutrition for Pain Relief in Fibromyalgia
Fibromyalgia (FMS) is characterized by chronic musculoskeletal pain, sleep disturbances, and fatigue. It is not entirely clear how Bcomplex vitamins affect the human pain system, while at the same time there have been approaches…
- Trial name
- NCT07863232
- Testing
- Melatonin 1mg and intravenous B-complex vitamin drip
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Osteoarthritis (OA) of the Knee
PCL Retention Versus Sacrifice During Total Knee Replacement With a Medial Pivot Prosthesis
otal knee replacement is a common treatment for patients with severe knee osteoarthritis when non-surgical treatments no longer provide adequate relief.
- Trial name
- NCT07849959
- Testing
- PCL Retention During Medial Pivot Total Knee Arthroplasty, PCL Sacrifice During Medial Pivot Total Knee Arthroplasty
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Weaning Mechanical Ventilation
External Validation of VVI
Failure of liberation from mechanical ventilation increases days spent being mechanically ventilated, the length of stay and the morbidity of patients.
- Trial name
- E-VVI (NCT07372664)
- Where
- 3 sites in Greece
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Healthy
Evaluation of the Acceptability of a Multi-strain Probiotic Supplement (Smile Probio 45B) in Healthy Adults
The goal of this clinical trial is to examine the compliance and acceptability of the probiotic Smile Probio 45B in healthy adults, as well as its effect on gastrointestinal symptoms, fatigue levels, and quality of life.
- Trial name
- NCT07362251
- Testing
- Probiotic
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
IBD, Hypertension (HTN)
Acceptability, Adherence, and Impact on the Bioavailability of Iron and Zinc of the Dietary Supplements Goodphyte IB Defense and Goodphyte Immunity in Adults With Chronic Diseases.
The primary objective of the present postdoctoral research is to evaluate the acceptability and adherence of two dietary supplements containing microbial phytase, Goodphyte IB Defense and Goodphyte Immunity, in adult individuals…
- Conditions
- IBD, Hypertension (HTN), Multiple Sclerosis, Anemia
- Trial name
- PHYTASE (NCT07380022)
- Testing
- Dietary supplement intervention Goodphyte IB Defense, Dietary supplement intervention Goodphyte Immunity
- Where
- Greece
- Volunteers
- 100 people
- Sponsor
- University of Thessaly
Temporomandibular Joint Disorder
Validation and Cultural Adaptation of Jaw Functional Limitation Scale-20
Temporomandibular joint (TMJ) disorder (TMD) is common. Jaw Functional Limitation Scale-20 (JFLS) is a validated tool for the evaluation of patients suffering from TMD
- Trial name
- NCT07789197
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Supportive Care, Exercise Adaptations
Intradialytic Exercise and Cognitive Function
Exercise training may improve global and domain-specific cognitive function, mental health, psychological well-being, dialysis efficacy, and health-related quality of life in people with end-stage kidney disease receiving…
- Conditions
- Supportive Care, Exercise Adaptations, Exercise Training Therapy, Clinical Exercise
- Trial name
- EXCOG-HD (NCT07780175)
- Testing
- Resistance Training, Aerobic training, Combination Training
- Where
- Cyprus
- Volunteers
- 60 people
- Sponsor
- University of Thessaly
Obesity
Chrono-Fasting in Overweight and Obese Adolescents
Childhood and adolescent obesity represents a major global public health concern, with a steadily increasing prevalence over recent decades, accompanied by a rise in metabolic disorders among younger populations.
- Trial name
- ChronoFasting (NCT07759414)
- Testing
- Early TRF, late TRF, Control
- Where
- Greece
- Volunteers
- 120 people
- Sponsor
- University of Thessaly
Antibiotic Therapy
Acceptability and Adherence to Different Dosing Regimens of the Multistrain Probiotic Vivomixx Neo® 460 in Adults Receiving Antibiotic Therapy.
This open-label interventional study aims to evaluate the acceptability and adherence of adult participants to the multistrain probiotic Vivomixx Neo® 460 when administered concurrently with antibiotic therapy.
- Trial name
- Vivomixx neo® (NCT07380009)
- Testing
- One sachet of the probiotic daily, Two sachets of the probiotic daily
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- University of Thessaly
Carpometacarpal (CMC) Joint Arthritis
Mini TightRope Suspensionplasty Versus Ligament Reconstruction and Tendon Interposition for Thumb Carpometacarpal Osteoarthritis
Thumb carpometacarpal osteoarthritis is a common cause of pain, weakness and functional disability. Trapeziectomy with ligament reconstruction and tendon interposition (LRTI) is considered a standard surgical procedure, whereas…
- Trial name
- NCT07698301
- Testing
- Mini tightrope suspensionplasty, Ligament Reconstruction and Tendon Interposition (LRTI)
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Theodoros Mylonas
Performance Recovery, Exercise-induced Inflammation
S-Acetyl Glutathione and Performance Recovery in Soccer
Soccer players display elevated inflammatory and oxidative stress markers combined with reduced soccer specific performance over a 72-hour period.
- Conditions
- Performance Recovery, Exercise-induced Inflammation, Exercise-induced Oxidative Stress
- Trial name
- NCT07690124
- Testing
- 200 mg S-Acetyl Glutathione, 500 mg S-Acetyl Glutathione
- Where
- Greece
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Metabolic Health, Mental Health
Health Benefits of Dance Exercise
In Greece, people of different age groups, including young children to older adults, participate in dance exercise training. Although it is well-known that regular participation in dancing is associated with benefits such as…
- Conditions
- Metabolic Health, Mental Health, Physical Performance
- Trial name
- NCT07615829
- Testing
- Exercise training, No exercise training
- Where
- Greece
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Heat Strain
Mitigation of Health Effects in Outdoor Workers by Reducing Exposure to Heat and Air Pollution
The goal of this clinical trial is to assess the effectiveness of an intervention (combination of behavioural recommendations and technical measures) in reducing personal exposure to heat and air pollution and related health…
- Trial name
- ISMED-CLIM OW (NCT07634952)
- Testing
- Heat intervention, Heat and air pollution mitigation intervention
- Where
- 2 sites in Greece, Spain
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- University of Cyprus
Obesity & Overweight
Long-term Adaptations of Skeletal Muscle After Hybrid Training
Obesity is a major challenge for public health and renders it imperative to reduce its prevalence. High intensity interval training (HIIT) is a form of exercise training that can efficiently induce weight loss in adults with…
- Trial name
- NCT07341711
- Testing
- Exercise training, Control group
- Where
- Greece
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Thessaly