Clinical trials: sponsored by Vrije Universiteit Brussel
Stroke, Spinal Cord Injuries (SCI)
Long-Term Clinical, Health Economic, and Process Evaluation of Intensive Technology-Integrated Motor Rehabilitation in Chronic Neurological Conditions (INTeRAcT-bis)
Rehabilitation remains important in the chronic phase after stroke or spinal cord injury, as meaningful improvements may still be achieved through intensive, goal-directed, and personalized training.
- Conditions
- Stroke, Spinal Cord Injuries (SCI), Chronic Disease
- Trial name
- INTeRAcT-bis (NCT07912320)
- Testing
- Intensive rehabilitation programme
- Where
- 2 sites in Belgium
- Volunteers
- 100 people
- Sponsor
- KU Leuven
Gait Disorders in Old Age, Gait Disorders, Neurologic
Walking With the SAIRE Smart Walker
The current study aims to investigate the effect of walking with the SAIRE smart walker on spatiotemporal parameters and gait kinematics in a population who suffer from difficulties during gait, and compare this to walking with a…
- Conditions
- Gait Disorders in Old Age, Gait Disorders, Neurologic, Walking, Difficulty
- Trial name
- SAIRE (NCT05461677)
- Testing
- SAIRE smart walker, Standard 4-wheeled walker, No walking aid
- Where
- Belgium
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Hospital Associated Disability, Immobility
Targeting Muscle Strength Loss Due to Hospitalization in Older Adults by Blood-flow Restriction Combined With an Electromyography-driven Serious Game.
This study investigates a new training method designed to help older adults preserve their muscle strength during hospitalization.
- Conditions
- Hospital Associated Disability, Immobility, Older Adults (65 Years and Older)
- Trial name
- GHOSTLY+ (NCT07294131)
- Testing
- Gamified isometric strength training with blood flow restriction, Standard Physiotherapy
- Where
- 3 sites in Belgium
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Expert Opinion on the Development of Serious Games for Rehabilitation
Development of Serious Games for Rehabilitation: a Delphi Study
This clinical study has been organised to identify the needs and recommendations of experts in the field of rehabilitation technology and gamification on the development of serious games for rehabilitation.
- Trial name
- NCT07460778
- Testing
- Online survey, Focus group discussions, Ranking results
- Where
- Belgium
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Stroke, COVID-19
Strength Training in Hospitalized Patients Using the Ghostly App: a Feasibility Study
The goal of this feasibility study is to evaluate the use of the Ghostly app in rehabilitation of stroke patients, elderly and patients recovering from COVID-19 or ICU patients.
- Conditions
- Stroke, COVID-19, Frailty, Muscle Weakness
- Trial name
- NCT05258500
- Testing
- Ghostly app, Blood flow restriction, Leaflet
- Where
- 2 sites in Belgium
- Volunteers
- 15 people
- Sponsor
- Vrije Universiteit Brussel
Stroke, Parkinson Disease
Exploratory Study About the Implementation of Technology in the Rehabilitation
This qualitative study aims to identify the needs and recommendations of both patients and healthcare professionals in terms of rehabilitation technology, more specific three pre-defined user scenarios.
- Conditions
- Stroke, Parkinson Disease, Covid19, Neglect, Hemispatial
- Trial name
- NCT04833088
- Testing
- Focus group discussions
- Where
- Belgium
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Knee Osteoarthritis
The Effect of Theory-driven Physiotherapy on Physical Activity in Knee OA.
Knee osteoarthritis (OA) is a leading cause of pain, disability, and reduced physical functioning worldwide. Although physiotherapy and physical activity are recommended as first-line treatments, many individuals with knee OA do…
- Trial name
- EXPLOR (NCT07901881)
- Testing
- EXPLOR-3
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Mark van Loo
Healthy
The Effect of Thermotherapy on Recovery and Performance
This study investigates the effects of cooling on the recovery and performance characteristic in young healthy subjects. The study is divided in two projects: Project A: investigates the effects of 20 min.
- Trial name
- Cryotherapy (NCT02506283)
- Testing
- Zamar Therapy CT clinic
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences and Arts of Southern Switzerland
Neoplasms, Cancer Survivorship
Effectiveness of a Guided, Web-based, Stepped-care-approach to Cognitive Behavioral Therapy for Insomnia in Cancer Survivors
The goal of this multicenter randomized clinical trial is to develop and evaluate a web-based stepped-care approach to Cognitive Behavioral Therapy for Insomnia (CBT-I), specifically tailored to adult cancer survivors…
- Conditions
- Neoplasms, Cancer Survivorship, Insomnia
- Trial name
- eNightfall (NCT07876661)
- Testing
- Stepped-care Cognitive Behavioral Therapy for Insomnia, Standard web-based Cognitive Behavioral Therapy for Insomnia, Control arm - Care as usual with sleep hygiene leaflet
- Where
- Belgium
- Volunteers
- 140 people
- Sponsor
- Vrije Universiteit Brussel
Social Isolation, Isolated Confined and Extreme Conditions
The Impact of Long-term Isolation in Antarctica on Social Touch and Its Underlying Biological Mechanisms in Winter-over Crew Members, Assessed During Their Stay Using Standardized Touch Stimulation, Computer-based Touch Sensitivity Tests, Questionnaires and Biological Markers.
TACTICE investigates how long-term isolation and reduced social touch during an Antarctic winter-over affect the way people perceive and respond to touch.
- Trial name
- TACTICE (NCT07858240)
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 28 people
- Sponsor
- Vrije Universiteit Brussel
Psychiatric Disorder
Cognitive Model for Behavioral Interventions as a Personalized Intervention for Patients With Serious Mental Illness
The aim of this clinical study is to investigate whether CoMBI-SMI helps to reduce behavioral problems and psychiatric complaints in Serious Mental Illness (SMI) populations complaints and to reduce the burden on informal…
- Trial name
- NCT05820360
- Testing
- CoMBI-SMI
- Where
- Netherlands
- Volunteers
- 94 people
- Sponsor
- Vrije Universiteit Brussel
Knee Osteoarthritis, Oxidative Stress
The Effect of Training on Oxidative Stress in Patients With kneeOA.
A six week patient study that intends to prove that training helps improve the life of people with osteoatritis of the knee. It looks at pain and function in daily life and markers in the blood that show stress at a cell level.
- Trial name
- 24008_Protarth (NCT07845838)
- Testing
- supervised training, daily walking
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Mariette Boshuis
Fatigue, Older Adults (65 Years and Older)
Exploring the Effect of the Hypershell Hip Exoskeleton on Fatiguing, Everyday Activities in Older Adults
The goal of this clinical trial is to learn how wearing the Hypershell lower-limb exoskeleton affects perceived fatigue during everyday mobility activities in adults aged 65 years and older.
- Conditions
- Fatigue, Older Adults (65 Years and Older), Exoskeleton Device
- Trial name
- Hypershell (NCT07840872)
- Testing
- Performance test, Hypershell assistance (EXO-ON Actuation)
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Mass Casualty Incident Preparedness, Simulation-Based Medical Education
Mass-Casualty Incident - Prehospital Emergency Response
The goal of this study was to learn whether the MCIPHER memory aid could help first-year resident doctors manage a simulated mass-casualty incident.
- Trial name
- MCIPHER (NCT07838441)
- Testing
- Standard Mass-Casualty Incident Curriculum, MCIPHER mnemonic pre-brief, Tabletop Simulation
- Where
- United Arab Emirates
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Healthy, Stroke
The Influence of Cortical Lateralization on Selective Motor Control of the Arm Swing During Independent Walking After Stroke.
The upper limbs play an essential role for safe and efficient walking in healthy persons and persons post-stroke. Nevertheless, in current post-stroke gait rehabilitation (research) the upper limbs are barely targeted.
- Trial name
- NCT06442579
- Testing
- Walking on a treadmill
- Where
- 2 sites in Belgium
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Fibromyalgia, Chronic Low Back Pain
Mapping Stress and Pain Interactions (G072323N)
The over-arching goal of this observational (case-control, with a cross-sectional and longitudinal arm) study is to comprehensively map stress system (dys)function (including reactivity and recovery) in people with primary…
- Conditions
- Fibromyalgia, Chronic Low Back Pain, Subacute Low Back Pain
- Trial name
- STRAIN (NCT06892977)
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Ghent
HIV-1-infection, HIV Seropositivity
Immuno-virological Evaluation of Persons Living With HIV (PLWH)
This is a dual arm (arm 1 and arm 2) multi-centric non-randomized (prospective) study. Two new multicentric cohorts will be set up in 4 Belgian HIV reference centers (UZ Gent, UZ Brussel, University Hospital Liege and St.
- Trial name
- NCT05973825
- Testing
- Leucapheresis
- Where
- Belgium
- Volunteers
- 24 people
- Sponsor
- University Hospital, Ghent
Healthy Adolescents in School-based Population, Emotional Neglect
Recognizing Emotional Neglect and Help-Seeking Intention Among Adolescents in Brussels
The goal of this study is to find out how well adolescents in Dutch-speaking secondary schools in Brussels can recognize emotional neglect, and how this relates to their intention to seek help. The main research questions are: 1.
- Conditions
- Healthy Adolescents in School-based Population, Emotional Neglect, Help-Seeking Behavior
- Trial name
- NCT07365891
- Testing
- Emotional neglect vignettes
- Where
- Belgium
- Volunteers
- 749 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Chronic Diseases in Children
Using a Humanoid Robot to Distract Children With Chronic Conditions Undergoing Painful Procedures
The aim of this study is to examine the effect of using a humanoid robot during a painful puncture procedure (e.g., portal catheter punction, IV punctures, blood withdrawal, etc.) in children with chronic conditions (e.g.…
- Trial name
- NCT04003701
- Testing
- Usual care, Robot-assisted puncture procedure
- Where
- Belgium
- Volunteers
- 22 people
- Sponsor
- Vrije Universiteit Brussel
Sleep Problems, Parasomnias
Sleep in Children Placed in Out-of-home Care
This project aims to contribute to the existing literature on sleep in children placed in out-of-home care by addressing current gaps and integrating the investigation of sleep and associated risk factors, including adverse…
- Conditions
- Sleep Problems, Parasomnias, Enuresis Nocturnal
- Trial name
- NCT07820683
- Testing
- Sleep and Adjustment in Foster care Environments (SAFE) intervention, Sleep Education Support
- Volunteers
- 730 people
- Sponsor
- Vrije Universiteit Brussel