Tooth EruptionNCT04675203
Molecular Mechanisms of Tooth Eruption
An observational study of Tooth Eruption, run by University Hospital, Strasbourg, France at 1 site in France.
Trial summary
The main objective is to study the expression of molecules involved in tooth morphogenesis and eruption in healthy patients, and then to compare them with the results in patients with abnormalities of eruption (results obtained via a collection of biological samples of rare diseases already authorized). Read more about this study
- Who is it for?
- Ages 12 years and older
- Conditions the study is for
- Tooth Eruption
- What is being tested?
- Tooth extraction
- Type of treatment
- Surgery or procedure
- How many people
- 50 participants
- Where
- 1 siteFrance
- Study dates
- Mar 2021to Jan 2023
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 years and older
- All sexes
- No healthy volunteers
- Child, Adult, Older adult
Study population: Primary care clinic (Hôpitaux Universitaires de Strasbourg, France)
Who may be able to join
- Patient over 12 years old who has given his consent
- Patient whose legal representatives have given their consent for the use of operating waste destined for incineration
- Patient undergoing oral surgery at the University Hospitals of Strasbourg, at the origin of the production of surgical waste such as teeth and bone fragments
- Patient affiliated to a social security system
Who cannot join
- Refusal to participate
- Patient with chronic systemic pathology
- Patient under long-term drug treatment
- Patient presenting a rare pathology with oral manifestation
- Patient with a history of chemotherapy or head and neck radiotherapy
- Non-French speaking patient / inability to give informed information
- Patient under guardianship, curatorship or legal protection
Trial locations and contacts
1 site in 1 country.
France1 site
Les Hôpitaux Universitaires de Strasbourg
Strasbourg, 67091
Marion STRUB, +33 3 88 69 56, marion.strub@chru-strasbourg.fr
Marion STRUB
About this study
The main objective is to study the expression of molecules involved in tooth morphogenesis and eruption in healthy patients, and then to compare them with the results in patients with abnormalities of eruption (results obtained via a collection of biological samples of rare diseases already authorized).
- Conditions
- Tooth Eruption
- Being tested
- Tooth extraction
- Medical subject headings
- Exanthema
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Tooth extractionProcedure or surgery
Tooth extraction
| Study group | Role | What they receive |
|---|---|---|
| Normal tooth eruption | Not described Receives: Procedure: Tooth extraction |
What is being measured
The primary outcome is the main question the study is designed to answer.
Expression and localization of molecules involved in tooth eruption
Tissues are collected at the time of surgery and transferred during the day to the laboratory for analysis
Measured: During surgery
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Dec 2020
- Study startMar 2021 (estimated)
- Primary completionMar 2021 (estimated)
- Study completionJan 2023 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tooth EruptionStudies of the same condition, open and under way.
- More trials run by University Hospital, Strasbourg, FranceThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital, Strasbourg, France
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT04675203
- Sponsor's protocol ID
- 7946
- Status last verified
- Mar 2021
- First submitted
- 14 Dec 2020
- Last updated
- 30 Mar 2021
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Study at a glance
From the registry record, last updated by the sponsor on 30 Mar 2021. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Molecular Mechanisms of Tooth Eruption
- ClinicalTrials.gov ID
- NCT04675203
- Acronym / sponsor ID
- 7946
- Conditions
- Tooth Eruption
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- University Hospital, Strasbourg, FranceUniversity, hospital or other
- Study start
- Mar 2021 (estimated)
- Primary completion
- Mar 2021 (estimated)
- Study completion
- Jan 2023 (estimated)
- First posted
- 19 Dec 2020 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The main objective is to study the expression of molecules involved in tooth morphogenesis and eruption in healthy patients, and then to compare them with the results in patients with abnormalities of eruption (results obtained via a collection of biological samples of rare diseases already authorized).
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Normal tooth eruption | – | Procedure: Tooth extraction |
Who may qualify
- Ages
- 12 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Primary care clinic (Hôpitaux Universitaires de Strasbourg, France)
Key inclusion criteria (4 listed)
- Patient over 12 years old who has given his consent
- Patient whose legal representatives have given their consent for the use of operating waste destined for incineration
- Patient undergoing oral surgery at the University Hospitals of Strasbourg, at the origin of the production of surgical waste such as teeth and bone fragments
- Patient affiliated to a social security system
Key exclusion criteria (7 listed)
- Refusal to participate
- Patient with chronic systemic pathology
- Patient under long-term drug treatment
- Patient presenting a rare pathology with oral manifestation
- Patient with a history of chemotherapy or head and neck radiotherapy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Tooth extractionTooth extraction | Procedure or surgery | Normal tooth eruption |
Primary outcome
Expression and localization of molecules involved in tooth eruption
Time frame: During surgery
Tissues are collected at the time of surgery and transferred during the day to the laboratory for analysis
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 30 Mar 2021.
- Individual participant dataSharing planned: Undecided
Related trials for Tooth Eruption
Not yet recruiting
Accuracy of Stackable Double Periodontal Guide in Esthetic Crown Lengthening
Gummy Smile of Altered Passive Eruption Type 1B
Recruiting
The Effectiveness of Early Intervention to Correct the Position of PDC:s
Ectopic Tooth Eruption, Palatal Expansion Technique
Not yet recruiting
Risk Factors for Tooth Eruption Diseases
Tooth Eruption Disorder
Recruiting
Periodontal Tissue Stability After Surgical Correction of Altered Passive Eruption
Altered Passive Eruption
Enrolling by invitation
Laser-Assisted Minimally Invasive Esthetic Crown Lengthening Using Flapless vs. Tunneled Flap Approach
Altered Passive Eruption of Teeth
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Tooth Eruption, run by University Hospital, Strasbourg, France at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 30 Mar 2021. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact Marion STRUB (+33 3 88 69 56, marion.strub@chru-strasbourg.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Expression and localization of molecules involved in tooth eruption (time frame: During surgery). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 30 Mar 2021.