Tooth ExtractionNCT07044895
Diode Laser Photocoagulation With Immediate Implant Placement
A study testing Diode laser and Immediate implant in people with Tooth Extraction and Immediate Dental Implant, run by Hams Hamed Abdelrahman at 1 site in Lebanon.
Trial summary
Placement of an immediate implant is becoming popular because of its potential in minimizing the treatment time and enhancing the patient comfort and esthetic outcomes. It is crucial to maintain adequate thickness of labial bone with the establishment of a stable and healthy gingival seal around the implant abutment… Read more about this study
- Who is it for?
- Ages 18 to 40 years
- Conditions the study is for
- Tooth Extraction, Immediate Dental Implant, Photocoagulation
- What is being tested?
- Diode laser and Immediate implant
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 8 participants
- Where
- 1 siteLebanon
- Study dates
- 30 Jun 2025to 25 Feb 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Patients with non-restorable maxillary teeth in the aesthetic zone are indicated for extraction and subsequent immediate implant placement, including those with:
- A severely carious tooth that cannot be restored.
- Pulpal necrosis or irreversible pulpitis that is not amenable to endodontics.
- Periodontally involved teeth with grade 2 mobility or above.
- Teeth with root caries that can't be restored.
- Patients with an extraction socket Type I.
- A good standard of oral hygiene.
Who cannot join
- Patients with extraction socket Type II or III, with buccal plate defects.
- Absence of at least 2 mm of bone apical to the extraction socket
- tooth ankylosis.
- Patients with deciduous teeth.
- Heavy smokers.
- Systemic conditions
- History of oral or intravenous bisphosphonate therapy or any treatments with other medications that may interfere with bone metabolism within the past 12 months
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Lebanon1 site
Faculty of Dentistry clinics, Beirut Arab University
Beirut
Amina R Ali, BDS
Amina R Ali, BDS
About this study
Official title: Evaluation of Diode Laser Photocoagulation With Immediate Implant Placement in the Maxillary Esthetic Zone
Placement of an immediate implant is becoming popular because of its potential in minimizing the treatment time and enhancing the patient comfort and esthetic outcomes. It is crucial to maintain adequate thickness of labial bone with the establishment of a stable and healthy gingival seal around the implant abutment to prevent the invasion of bacteria and peri-implant inflammation. Diode lasers have been developed as a promising tool in dentistry, providing a precise manipulation and photocoagulation effect that may have a positive influence on both bone remodeling and soft tissue healing. This study aims to evaluate the effectiveness of the utilization of diode laser photocoagulation with immediate implant placement and customized healing abutment in the maxillary esthetic zone.
- Being tested
- Diode laser and Immediate implant
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Diode laser and Immediate implantOther
patients with non-restorable teeth in the maxillary esthetic zone will be included in this prospective single-arm study. The non-restorable tooth will be atraumatically extracted and immediate implant placement will be placed. The extraction socket will be sealed with diode laser photocoagulation and customized healing abutments fabrication.
| Study group | Role | What they receive |
|---|---|---|
| Immediate implant with photocoagulation | Experimental | Not described Receives: Other: Diode laser and Immediate implant |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in pain socres
Pain will be evaluated, using visual analogue scale (VAS) as follows:
(0-1= None, 2-4= Mild, 5-7= Moderate, 8-10= Severe)
Measured: at 7, 14, and 21 days
Change in wound healing
The wound healing will be assessed based on Landry Wound Healing Index. The Landry Index uses a numerical score based on the assessment of four given parameters (Erythema, Edema, Wound Margin Adaptation, and Presence of Exudate). Each parameter is given a score depending on its severity, and the total score determine an overall evaluation of wound healing
Measured: at 7, 14, and 21 days
Change in implant stability
The base line primary Implant Stability Quotient (ISQ) will be measured during the operative stage, while the secondary stability quotient will be measured 6-months post-operative during the prosthetic phase preparation.
Measured: baseline and 6 months
Secondary outcomes (3)
Change in Crestal Alveolar Process width
The width of the crestal alveolar process will be assessed by determination of the dimensional changes of Bucco-palatal ridge in the 6 months' scan
Measured: baseline and 6 months
Change in labial bone thickness
The overall persistence of the labial plate of bone after the atraumatic extraction and immediate implant placement will be evaluated by the assessment of the thickness labial plate of bone in the scan performed after 6 months and comparing it with the preoperative CBCT record. The distance will be measured from the root surface to the outer buccal bone surface in the preoperative CBCT record. Measurements will be performed on the cross-sectional cut of the CBCT at three levels; crestal labial thickness, middle labial thickness, and apical labial thickness.
Measured: baseline and 6 months
Change in esthetic of soft tissue
The pink esthetic score (PES) introduced by Furhauser et al will be used for evaluation of the esthetic outcome of soft tissue surrounding single crowns supported by implant in the esthetic zone. The PES consists of seven factors each one is given a score of 2, 1, or 0, and a total score will be ranging between 0 and 14
Measured: at 1 month
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Jul 2025
- Study start30 Jun 2025 (estimated)
- Primary completion25 Feb 2026 (estimated)
- Study completion25 Feb 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tooth ExtractionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 8 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Hams Hamed Abdelrahman
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Hams Hamed Abdelrahman, Alexandria University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT07044895
- Sponsor's protocol ID
- 2025-H-0167-D-M-0754
- Status last verified
- Jun 2025
- First submitted
- 22 Jun 2025
- Last updated
- 1 Jul 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 1 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of Diode Laser Photocoagulation With Immediate Implant Placement in the Maxillary Esthetic Zone
- ClinicalTrials.gov ID
- NCT07044895
- Acronym / sponsor ID
- 2025-H-0167-D-M-0754
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 8 participants (estimated)
- Lead sponsor
- Hams Hamed AbdelrahmanUniversity, hospital or other
- Study start
- 30 Jun 2025 (estimated)
- Primary completion
- 25 Feb 2026 (estimated)
- Study completion
- 25 Feb 2026 (estimated)
- First posted
- 1 Jul 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Placement of an immediate implant is becoming popular because of its potential in minimizing the treatment time and enhancing the patient comfort and esthetic outcomes. It is crucial to maintain adequate thickness of labial bone with the establishment of a stable and healthy gingival seal around the implant abutment to prevent the invasion of bacteria and peri-implant inflammation. Diode lasers have been developed as a promising tool in dentistry, providing a precise manipulation and photocoagulation effect that may have a positive influence on both bone remodeling and soft tissue healing. This study aims to evaluate the effectiveness of the utilization of diode laser photocoagulation with immediate implant placement and customized healing abutment in the maxillary esthetic zone.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Immediate implant with photocoagulation | Experimental | Other: Diode laser and Immediate implant |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Patients with non-restorable maxillary teeth in the aesthetic zone are indicated for extraction and subsequent immediate implant placement, including those with:
- A severely carious tooth that cannot be restored.
- Pulpal necrosis or irreversible pulpitis that is not amenable to endodontics.
- Periodontally involved teeth with grade 2 mobility or above.
- Teeth with root caries that can't be restored.
Key exclusion criteria (7 listed)
- Patients with extraction socket Type II or III, with buccal plate defects.
- Absence of at least 2 mm of bone apical to the extraction socket
- tooth ankylosis.
- Patients with deciduous teeth.
- Heavy smokers.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Diode laser and Immediate implantpatients with non-restorable teeth in the maxillary esthetic zone will be included in this prospective single-arm study. The non-restorable tooth will be atraumatically extracted and immediate implant placement will be placed. The extraction socket will be sealed with diode laser photocoagulation and customized healing abutments fabrication. | Other | Immediate implant with photocoagulation |
Primary outcome
Change in pain socres
Time frame: at 7, 14, and 21 days
Pain will be evaluated, using visual analogue scale (VAS) as follows: (0-1= None, 2-4= Mild, 5-7= Moderate, 8-10= Severe)
Change in wound healing
Time frame: at 7, 14, and 21 days
The wound healing will be assessed based on Landry Wound Healing Index. The Landry Index uses a numerical score based on the assessment of four given parameters (Erythema, Edema, Wound Margin Adaptation, and Presence of Exudate). Each parameter is given a score depending on its severity, and the total score determine an overall evaluation of wound healing
Change in implant stability
Time frame: baseline and 6 months
The base line primary Implant Stability Quotient (ISQ) will be measured during the operative stage, while the secondary stability quotient will be measured 6-months post-operative during the prosthetic phase preparation.
3 secondary outcomes
Change in Crestal Alveolar Process width
Time frame: baseline and 6 months
Change in labial bone thickness
Time frame: baseline and 6 months
Change in esthetic of soft tissue
Time frame: at 1 month
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Jul 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Diode laser and Immediate implant in people with Tooth Extraction and Immediate Dental Implant, run by Hams Hamed Abdelrahman at 1 site in Lebanon.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 1 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Lebanon. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Amina R Ali, BDS (+961 70 908 487, dr_aminahweidi2016@hotmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in pain socres (time frame: at 7, 14, and 21 days). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Jul 2025; AzTrials last refreshed its copy on 29 Oct 2026.