Clinical trials: Bone Calcification
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Erb Palsy
Stretch-Shortening Cycle Exercise: Potential Implications For Children With Obstetric Brachial Plexus Injury
This study was set out to evaluate the effect of a 12-week stretch-shortening cycle exercise (SSC-Ex) on muscle strength, bone mineral density, and upper extremity function in children with obstetric brachial plexus injury…
- Trial name
- NCT06157476
- Testing
- Stretch-shortening exercise, Standard exercise program
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- Cairo University
Chronic Kidney Diseases
Assessing Bone Calcium Content in Children With Kidney Disease Treated With Two Different Medicines
This is an open label, time series trial. The trial is likely to be single centre (additional sites will only be opened if necessary) and will involve 25 children with chronic kidney disease (stage 3b, 4-5) or on dialysis.
- Trial name
- CAL-BAL (NCT04120922)
- Testing
- calcium carbonate, sevelamer carbonate
- Where
- United Kingdom
- Volunteers
- 21 people
- Sponsor
- University College, London
Osteoporosis
Building Better Bones in Children
Calcium is important for healthy bone growth in children. Poor bone growth and development during childhood can lead to osteoporosis later in life.
- Trial name
- NCT00063037
- Testing
- Behavioral modification - nutrition education
- Where
- United States
- Volunteers
- 139 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder
Chinese CKD-MBD Prevalence Survey (CRISS-MBD)
This is a multi-center cross sectional epidemiological study. The purpose of this study is to investigate the prevalence of Chronic Kidney Disease-Mineral and Bone Disorder (CKD-MBD) in Chinese population.
- Trial name
- NCT04714918
- Where
- 40 sites in China
- Volunteers
- 10,254 people
- Sponsor
- Limeng Chen
Renal Transplant
Effects of Zortress® + Tacrolimus vs. Standard Immunosuppression on Progression of Coronary Artery Calcifications and Bone Disease in de Novo Renal Transplant Recipients
Primary objectives: A. To evaluate the effect of Zortress® versus standard immunosuppression therapy on progression of CAC as evidenced by changes in Agatston scores from baseline and at 6, and 12 months in renal transplantation…
- Trial name
- NCT01612299
- Testing
- Zortress® /Everolimus
- Where
- United States
- Sponsor
- University of Kentucky
Bone Metabolism
The Effect of Testosterone Replacement on Bone Mineral Density in Boys and Men With Anorexia Nervosa
Decreased bone strength is a common and serious medical problem present in many people with anorexia nervosa. Men with anorexia nervosa have lower levels of gonadal steroids such as testosterone.
- Trial name
- NCT00853502
- Testing
- testosterone cypionate
- Where
- United States
- Sponsor
- Massachusetts General Hospital
HIV Infection
Vitamin D Absorption in HIV Infected Young Adults Being Treated With Tenofovir Containing cART
This is a 48 week randomized double-blind, placebo-controlled prospective cohort study of adolescents and young adults with HIV infection in the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) who are…
- Trial name
- NCT01751646
- Testing
- Vitamin D3 50,000 IU
- Where
- 17 sites in United States, Puerto Rico
- Volunteers
- 214 people
- Sponsor
- University of North Carolina, Chapel Hill
Postmenopausal Osteoporosis
A Study of Quarterly Intravenous Bonviva (Ibandronate) in Women With Post-Menopausal Osteoporosis.
This single arm study will assess the efficacy and safety of quarterly intravenous Bonviva in women with post-menopausal osteoporosis. All patients will receive Bonviva 3mg i.v. every 3 months.
- Trial name
- NCT00493532
- Testing
- ibandronate [Bonviva/Boniva]
- Where
- 14 sites in Taiwan
- Sponsor
- Hoffmann-La Roche
Osteoporosis
CR9112792, a Follow-up of Study CR9108963
The purpose of this study is to determine whether bone mineral density has increased in a subgroup of postmenopausal osteoporotic women from study CR9108963, between 6 and 12 months following cessation of ronacaleret therapy.
- Trial name
- NCT00891553
- Testing
- DXA
- Where
- 3 sites in Denmark, Norway
- Volunteers
- 171 people
- Sponsor
- GlaxoSmithKline
Type 1 Diabetes, Osteoporosis
Bone Health in Youth With Type 1 Diabetes
This is an observational study of children and young adults ages 6-20 years with type 1 diabetes and age- and race-matched controls.
- Trial name
- NCT02140424
- Where
- United States
- Volunteers
- 242 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Tumor Induced Osteomalcia, Osteomalacia
A Natural History Study of Bone and Mineral Disorders
This study has four objectives: 1) to provide investigators the opportunity to study bone specimens from patients with various skeletal diseases; 2) to treat patients with skeletal diseases at the NIH; 3) to expose NIH trainees…
- Conditions
- Tumor Induced Osteomalcia, Osteomalacia, Familial Tumoral Calcinosis
- Trial name
- NCT00024804
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Atherosclerosis, Cardiovascular Diseases
Joint Determinants of Bone Density and CVD Calcification
To evaluate the relationship bone marrow density and coronary artery and aortic calcification.
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases, Osteoporosis
- Trial name
- NCT00037414
- Volunteers
- 808 people
- Sponsor
- University of Maryland, Baltimore
HIV Infection, Bone Mass
The Effect of Vitamin D and Calcium on Bone in Pediatric HIV
We have observed that vitamin D deficiency, as evidenced by low serum 25(OH)D concentrations, is common in children and adolescents with HIV infection.
- Trial name
- NCT00724178
- Testing
- cholecalciferol plus calcium carbonate
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Unilateral Alveolar Cleft of Maxilla
Sticky Bone Grafting With Concentrated Growth Factor Membrane for Repair of Unilateral Alveolar Cleft
The aim of this study is to evaluate using Sticky Bone grafting combined with concentrated growth factor membrane for repair of unilateral alveolar cleft.
- Trial name
- NCT07066293
- Testing
- Unilateral alveolar cleft repair
- Where
- Egypt
- Volunteers
- 10 people
- Sponsor
- Tanta University
Bone Density, Osteopenia
Evaluation of Bone Mineral Density Indications and Outcomes in Female Adolescents: Implications for Early Detection of Osteopenia/Osteoporosis and Gynecologic Practice
This retrospective study evaluates bone mineral density (BMD) measurements obtained by dual-energy X-ray absorptiometry (DEXA) in adolescent girls aged 12 to 21 years at a tertiary care center.
- Conditions
- Bone Density, Osteopenia, Amenorrhea, Primary Amenorrhea
- Trial name
- TEEN-BMD (NCT07164248)
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Bagcilar Training and Research Hospital
Healthy
Bone Mineral Content in Healthy Children
The primary purpose of this study is to determine the effects of early diet on bone health.
- Trial name
- NCT01897168
- Testing
- No intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Amenorrhea
Retrospective Observational Evaluation of the Bone Mineral Density Outcome in Young Women With Amenorrhea
The study aims to evaluate the outcomes of different estrogen therapy regimens in patients with amenorrhea who face prolonged periods of hypoestrogenism.
- Trial name
- NCT07015476
- Where
- Italy
- Volunteers
- 180 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Hypercalciuria; Idiopathic, Nephrolithiasis
Comparison of the Impact of Diet vs Thiazide in BMD in Children With Idiopathic Hypercalciuria
The investigator's objective is to compare and evaluate the impact of nutritional treatment vs. pharmacological treatment (hydrochlorothiazide) in bone mineral density in children with idiopathic hypercalciuria.
- Trial name
- HIC (NCT03951558)
- Testing
- Diet for calciuria prevention, Hydrochlorothiazide
- Where
- Mexico
- Volunteers
- 90 people
- Sponsor
- Hospital Infantil de Mexico Federico Gomez