Clinical trials: Bone Calcification
Hypogonadism, Paraplegia
Efficacy of Nebido on Bone Mineral Density (BMD) in Hypogonadal Paraplegic Patients With Confirmed Osteoporosis
Both conditions hypogonadism and immobilisation (paraplegia) may contribute or lead to decreased bone mineral density resp osteoporosis.
- Conditions
- Hypogonadism, Paraplegia, Bone Density, Osteoporosis
- Trial name
- NCT00838838
- Testing
- Testosterone Undeconate (Nebido-R, BAY86-5037)
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Bayer
Postmenopausal Women
Relationship Between Homocysteine and BMD
The association between Homocysteine (Hcy) levels and bone mineral density (BMD) has been debated. Some studies have found a relationship between increased Hcy plasma levels and BMD in contrast; other studies have not found a…
- Trial name
- NCT04821492
- Testing
- Dual-Energy X-ray Absorptiometry (DXA)
- Where
- Spain
- Volunteers
- 760 people
- Sponsor
- Fundación Santiago Dexeus Font
Periprosthetic Osteolysis
Assessment of Periprosthetic Bone Mineral Density in Patients Undergoing Total Knee Prosthesis of Different Design
compare changes in BMD via DXA at the level of the femoral and tibial periprosthetic bone between two groups of patients undergoing cemented TKA of different design (posterior stabilization vs posterior cruciate preservation)…
- Trial name
- DXA-TKA (NCT06309433)
- Testing
- dual energy x-ray absorptiometry
- Where
- 2 sites in Italy
- Volunteers
- 50 people
- Sponsor
- Istituto Ortopedico Rizzoli
Osteoporosis
The Nitrate and Bone Study: Effects of Nitrates on Osteoporosis
Osteoporosis or "thinning of the bones" affects in 1 in 4 Canadian women and 1 in 8 Canadian men. Moreover, while the rates of osteoporosis among Canadians are stabilizing, worldwide the number of people afflicted with…
- Trial name
- NCT00252421
- Testing
- Nitroglycerin ointment 15 mg/day daily for 24 month
- Where
- Canada
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Diabetes Mellitus, Osteoporosis
Type 1 Diabetes Mellitus Effect on Bone Mineral Density
Because the diabetics are fracturing at a younger age than the general population (12), this leads us to believe there are significant factors that lead to fracture in Type 1 diabetes mellitus (DM) other than bone mineral density…
- Trial name
- NCT01633684
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Creighton University
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Total Hip Arthroplasty
Bone Remodeling Around a Trabecular Titanium Cup in Total Hip Arthroplasty
The goal of this randomized controlled trial is to measure the periprosthetic bone mineral density changes around a 3D-printed highly-porous titanium acetabular cup used in primary total hip arthroplasty compared to a standard…
- Trial name
- NCT06287021
- Testing
- Jump System Traser® cup, Jump System HAX-Pore® cup
- Where
- 2 sites in Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Permedica spa
Osteopenia, Osteoporosis
Time-specific Exercise in Circadian Context
The project aims to explore the mechanisms, by which physical activity can support healthy ageing and decrease the negative impact of ageing on the circadian system, musculoskeletal system and immunity.
- Conditions
- Osteopenia, Osteoporosis, Aging
- Trial name
- CAEx (NCT06746649)
- Testing
- Combined training
- Where
- Slovakia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Comenius University
Erb Palsy
Stretch-Shortening Cycle Exercise: Potential Implications For Children With Obstetric Brachial Plexus Injury
This study was set out to evaluate the effect of a 12-week stretch-shortening cycle exercise (SSC-Ex) on muscle strength, bone mineral density, and upper extremity function in children with obstetric brachial plexus injury…
- Trial name
- NCT06157476
- Testing
- Stretch-shortening exercise, Standard exercise program
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- Cairo University
Osteoarthritis
Bone Mineral Density (BMD) in Cemented Versus Cementless Hip Resurfacing
The purpose of this study is to compare the bone mineral density of patients who have undergone either cemented or cementless hip resurfacing.
- Trial name
- NCT01353326
- Testing
- Cormet, Conserve
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Ottawa Hospital Research Institute
Epithelial Ovarian Cancer, Efficacy
Fluzoparib in Combination With Apatinib Mesylate for Maintenance Therapy in Stage III-IV Ovarian Cancer
This study is a single-arm, open, multicenter, exploratory clinical study to observe and evaluate the efficacy and safety of fluazoparib combined with apatinib mesylate in the treatment of patients with ovarian cancer.
- Conditions
- Epithelial Ovarian Cancer, Efficacy, Safety, Bone Mineral Density
- Trial name
- NCT06539091
- Testing
- Fluzoparib, Apatinib Mesylate
- Volunteers
- 51 people
- Sponsor
- Anhui Provincial Hospital
Growth Hormone Disorder, Adult Growth Hormone Deficiency
Effect of Growth Hormone on Bone Mineral Density in Young Adults With Child-hood Onset Growth Hormone Deficiency
This trial is conducted in Europe. Growth Hormone in young adults with growth hormone deficiency in childhood. This trial compares a treated group of patients with an untreated group of patients.
- Trial name
- NCT00184678
- Testing
- somatropin
- Where
- 30 sites in Australia, Austria and 10 more
- Volunteers
- 161 people
- Sponsor
- Novo Nordisk A/S
Burns
Efficacy of Selected Exercises on Bone Mineral Density in Post-burn Patients
PURPOSE: to assess the efficacy of Qigong exercise on bone mineral density in post-burned patient. BACKGROUND: During severe burns, more than 7% of the vertebral bone mineral density (BMD) is lost within 3-6 weeks of the injury…
- Trial name
- NCT05276843
- Testing
- Qigong exercise program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Eman Mohamed othman
Residual Bone Height, Marginal Bone Loss
Influence of Residual Bone Height on Marginal Bone Loss Around Implants Following Lateral Sinus Floor Augmentation With Deproteinized Bovine Bone Mineral
Data collection will be done on all patients who underwent a lateral maxillary sinus floor augmentation in the Faculty of Dental Medicine, both in the Periodontology Department and in the Oral Surgery Department.
- Conditions
- Residual Bone Height, Marginal Bone Loss, Implant Type, Smoking
- Trial name
- NCT07550491
- Testing
- sinus lift using DBBM
- Where
- Lebanon
- Volunteers
- 142 people
- Sponsor
- Saint-Joseph University
Resting Metabolic Rate, Bone Mineral Density, Low, Susceptibility to
The Health of Competitive Fitness Athletes
Fitness athletes emphasize the value of staying lean, muscular and defined, and motivates and inspires followers through social media.
- Conditions
- Resting Metabolic Rate, Bone Mineral Density, Low, Susceptibility to, Body Image, Perfectionism
- Trial name
- NCT03007459
- Testing
- Psychological health, Physiological health
- Where
- Norway
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Postmenopausal Osteoporosis, Iron Metabolism Disorders
Association of Serum Ferritin and Bone Mineral Density With Bone Metabolism in Chinese Healthy Postmenopausal Women
Large amounts of experimental and animal evidence have confirmed that iron accumulation is associated with bone loss. However, it is still lack of the clinical studies relating iron accumulation to bone loss, especially in the…
- Trial name
- NCT03512743
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital of Soochow University
Bone Mineral Density, Grip Strength
Reference Curve on Bone Mineral Density in Young Adult: French Multicenter Study
In men, the hope of lower life, the absence of equivalent of menopause and the existence of a higher peak bone mass are three factors that explain the lower incidence of osteoporosis in men.
- Conditions
- Bone Mineral Density, Grip Strength, Physical Performance
- Trial name
- COURDO (NCT03316625)
- Testing
- Bone densitometry measurement
- Where
- 3 sites in France
- Volunteers
- 151 people
- Sponsor
- Centre Hospitalier Régional d'Orléans
Osteoporosis, Osteopenia
A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
The purpose of this study is to determine whether in postmenopausal women with low bone mineral density, the mean percent change in total hip BMD in subjects receiving denosumab is not less than that observed in subjects…
- Trial name
- NCT00330460
- Testing
- Alendronate, Denosumab
- Volunteers
- 1,189 people
- Sponsor
- Amgen
Osteoporosis, Fractures
Determination of Optimum Age for DXA Screening for Osteoporosis in HIV - The Probono 1 Study
The purpose of this study is to determine the bone mineral density in male and female patients with HIV infection according to age groups.
- Conditions
- Osteoporosis, Fractures, HIV Infection
- Trial name
- Probono1 (NCT01669954)
- Where
- United Kingdom
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- King's College London