Clinical trials: Bone Calcification
Physical Activity, Nutrition
Physical Activity, Calcium, and Bone in Children
Doctors recommend that young children participate in daily physical activity to promote bone health. However, studies in adults show that physical activity and increased calcium intake cause noticeable benefits for bone health…
- Trial name
- NCT00000415
- Testing
- Physical activity, Calcium supplement
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- South Dakota State University
Bone Density, Low, Bone Mineral Density in Children With Graves' Disease
Bone Mineral Density in Children With Graves' Disease
to evaluate bone mineral density in children with graves' disease
- Trial name
- NCT06375096
- Testing
- evaluate bone mineral density
- Volunteers
- 100 people
- Sponsor
- Assiut University
Lupus Erythematosus, Systemic
Study to Evaluate the Natural History of Osteoporosis in Children and Adolescents With Systemic Lupus Erythematosus
This is a study to determine if people with Lupus have weak bones. Test which is a better method for detecting bone changes: Dual energy X-ray absorptiometry (DXA) Single energy quantitative computed tomography (SEQCT) Evaluate…
- Trial name
- BMD (NCT00582465)
- Where
- United States
- Volunteers
- 243 people
- Sponsor
- University of California, San Francisco
Turner Syndrome
Defining the Optimal Hormonal Replacement Therapy in Turner Syndrome
The purpose of this study is to examine whether a larger dosage of estrogen than the one used today will secure the development of a normal sized uterus and increase the strength of the bones in girls and young women with Turner…
- Trial name
- NCT00134745
- Testing
- estradiol
- Where
- Denmark
- Volunteers
- 43 people
- Sponsor
- Line Cleemann
Bone Mineral Density in Cow's Milk Allergic Patients
Young Adults With Life Threatening Cow's Milk Allergy: Risks of Decrease Bone Mineralization and Methods of Calcium Supplementation
Diet is the only source for calcium and the most important dietary source are dairy products. This presents a difficulty for children with IgE-mediated cow's milk allergy, who are unable to consume milk.
- Trial name
- NCT01930266
- Testing
- Experimental, Active comparator
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assaf-Harofeh Medical Center
Renal Transplant
Effects of Zortress® + Tacrolimus vs. Standard Immunosuppression on Progression of Coronary Artery Calcifications and Bone Disease in de Novo Renal Transplant Recipients
Primary objectives: A. To evaluate the effect of Zortress® versus standard immunosuppression therapy on progression of CAC as evidenced by changes in Agatston scores from baseline and at 6, and 12 months in renal transplantation…
- Trial name
- NCT01612299
- Testing
- Zortress® /Everolimus
- Where
- United States
- Sponsor
- University of Kentucky
Osteoporosis
GRACE - Study of AGN1 LOEP in Osteopenic and Osteoporotic Patients
The study is designed as a retrospective, single-center study for subjects previously treated with the AGN1 LOEP Kit. This will be a non-randomized and non-blinded study.
- Trial name
- NCT05966974
- Where
- Belgium
- Volunteers
- 44 people
- Sponsor
- AgNovos Healthcare, LLC
Scoliosis
Calcium + Vitamin D Supplementation for Low Bone Mass in Adolescent Idiopathic Scoliosis (AIS)
The purpose of this study is to determine whether Calcium and Vit D supplementation is effective for improving low bone mass in Girls with Adolescent Idiopathic Scoliosis (AIS).
- Trial name
- NCT01103115
- Testing
- Calcium 600mg plus Vit D 400 IU, Calcium 600mg plus Vit D 800 IU
- Where
- China
- Volunteers
- 330 people
- Sponsor
- Chinese University of Hong Kong
HIV Infection
Safety and Effectiveness of Alendronate for Bone Mineral Density in HIV-infected Children and Adolescents
HIV-infected children, youth, and adults have lower bone mineral density (BMD) than would be expected for HIV-uninfected people of similar age, weight and race. As the majority of perinatally HIV-infected U.S.
- Trial name
- NCT00921557
- Testing
- Alendronate, Calcium carbonate/vitamin D
- Where
- 10 sites in United States, Brazil and 1 more
- Volunteers
- 52 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Osteopenia, Osteoporosis
The Long-term Effect of Daily Jarlsberg Cheese Intake in Patient With Osteopenia
Aim: To estimate the effect of daily optimal efficacy dose (OED) of Jarlsberg cheese in patients with Osteopeni (OP). Study population: Post-menopausal women and men above 55 years of age in risk of Osteoporosis Treatment: Daily…
- Trial name
- PF-JB3 (NCT06358443)
- Testing
- Jarlsberg cheese
- Where
- Norway
- Volunteers
- 20 people
- Sponsor
- Meddoc
Bone Density, Osteopenia
Evaluation of Bone Mineral Density Indications and Outcomes in Female Adolescents: Implications for Early Detection of Osteopenia/Osteoporosis and Gynecologic Practice
This retrospective study evaluates bone mineral density (BMD) measurements obtained by dual-energy X-ray absorptiometry (DEXA) in adolescent girls aged 12 to 21 years at a tertiary care center.
- Conditions
- Bone Density, Osteopenia, Amenorrhea, Primary Amenorrhea
- Trial name
- TEEN-BMD (NCT07164248)
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people
- Sponsor
- Bagcilar Training and Research Hospital
Healthy
Bone Mineral Content in Healthy Children
The primary purpose of this study is to determine the effects of early diet on bone health.
- Trial name
- NCT01897168
- Testing
- No intervention
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
End Stage Renal Disease, Hyperparathyroidism, Secondary
Mineral and Bone Disorders Outcomes in Stage 5D of Chronic Kidney Disease
The MBD-5D is a prospective observational study with a case-cohort and a cohort design. Eligible patients are receiving hemodialysis and have secondary hyperparathyroidism.
- Trial name
- MBD-5D (NCT00995163)
- Where
- Japan
- Volunteers
- 8,020 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Autism Spectrum Disorder, Bone Diseases, Developmental
Bone Mass Accrual in Children With Autism Spectrum Disorder
This is a observational study to investigate the degree to which bone mineral density is impaired in boys with autism compared with typically developing controls.
- Trial name
- NCT03162445
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cerebral Palsy
Functional Progressive Resistive Training and Cerebral Palsy
Functional Progressive Resistive Exercise (FPRE) is a strengthening approach that combines functional movement activities with progressively increased resistance.
- Trial name
- NCT07675343
- Testing
- functional progressive resistive exercise and designed physical therapy program, designed physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Age-Related Osteoporosis
Training in a Local Community Aimed Upon Musculoskeletal Health Promotion for Postmenopausal Women
To minimize fracture risk, diverse and varied training of high intensity (multimodal training) is recommended to increase bone strength.
- Trial name
- NCT05164679
- Testing
- multimodal training (MMT)
- Where
- Denmark
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Neurodevelopment Outcome, Linear Growth
Micronutrient Enhancement for Development and Health in Adolescents - The MEDHA Study
MEDHA is a randomized controlled trial among 10-18 year old girls to examine the use-case of the United Nations International Multiple Micronutrient Antenatal Preparation (UNIMMAP) multiple micronutrient supplement (MMS)…
- Conditions
- Neurodevelopment Outcome, Linear Growth, Micronutrient Status, Bone Mineral Density
- Trial name
- MEDHA (NCT07695883)
- Testing
- Iron (60 mg)- folic acid (400 ug) [IFA], Multiple micronutrient supplement [MMS], Multiple micronutrient supplement Plus [MMS+]
- Where
- Bangladesh
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Osteopenia of Prematurity
The Effect of Physical Activity on Bone Mineralization and Immune System in Very Low Birth Weight Infants
Studies have demonstrated that brief (5-10 min a day) passive range-of-motion exercise is beneficial for bone development in very low birth weight (VLBW) preterm infants.
- Trial name
- NCT01042639
- Testing
- passive physical activity
- Where
- Israel
- Volunteers
- 45 people
- Sponsor
- Meir Medical Center
Hereditary Breast and Ovarian Cancer Syndrome, Osteoporosis
Zoledronate or Observation in Maintaining Bone Mineral Density in Patients Who Are Undergoing Surgery to Remove Both Ovaries
This randomized phase II trial is studying zoledronate to see how well it works compared to observation in maintaining bone mineral density in patients who are undergoing surgery to remove both ovaries.
- Conditions
- Hereditary Breast and Ovarian Cancer Syndrome, Osteoporosis, Ovarian Carcinoma
- Trial name
- NCT00305695
- Testing
- Laboratory Biomarker Analysis, Zoledronic Acid
- Where
- 95 sites in United States
- Volunteers
- 160 people
- Sponsor
- Gynecologic Oncology Group
Premature Ovarian Failure
Evaluation of Physiologic and Standard Sex Steroid Replacement Regimens in Women With Premature Ovarian Failure
The aim of the study is to determine whether physiological sex steroid replacement improves parameters of skeletal, cardiovascular and reproductive health of women treated with current sex steroid replacement regimens.
- Trial name
- NCT00732693
- Testing
- Ethinylestradiol / Norethisterone, Estradiol / Progesterone
- Where
- 2 sites in United Kingdom
- Volunteers
- 42 people
- Sponsor
- University of Edinburgh