Clinical trials: CAS
Childhood Apraxia of Speech
Treating Childhood Apraxia of Speech
The study will test two modifications to speech therapy for 40 school-age children with childhood apraxia of speech to determine how to improve treatment outcomes.
- Trial name
- NCT03238677
- Testing
- Speech Motor Chaining without Biofeedback, Biofeedback, Distributed Practice
- Where
- United States
- Volunteers
- 56 people
- Sponsor
- Syracuse University
Children
Children's Aid Societies: Differential Response and Wraparound Prevention Trial
The purpose of this study is to assess the cost-effectiveness of this Differential Wraparound model, in 5 Children's Aid Societies within Hamilton-Niagara Region, in preventing maltreatment cases from either becoming ongoing…
- Trial name
- NCT00559208
- Where
- Canada
- Volunteers
- 135 people
- Sponsor
- Hamilton Children's Aid Society
Emotional Resilience
A Network Analysis on the Role of Specific ER Abilities as ERFs for Distress and Mental Health, in Relation to CAs Exposure in the AYAs
This activity will aim to compare the network of emotional resilience factors and stress in adolescents and young adults depending on the childhood abuse exposure (considered moderator), using a network analysis approach.
- Trial name
- NCT06986928
- Testing
- No intervention will be applied.
- Where
- Romania
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Babes-Bolyai University
Malaria
Effectiveness and Cost-Effectiveness of a Rapid Diagnostic Test for Malaria
There is increasing evidence from African countries, including Burkina Faso, that at least in some settings/seasons the proportion of fevers attributable to malaria is low or very low: this means that the current strategy of…
- Trial name
- NCT00317590
- Testing
- Rapid Diagnostic Test for Malaria (Paracheck®)
- Where
- Burkina Faso
- Volunteers
- 4,000 people
- Sponsor
- Centro per le Malattie Tropicali
Wounds and Injuries, Traumatic Amputation
Monitoring and Treatment of Extremity Trauma for Mass Casualties in Difficult Contexts
The prospective cohort study, SuTra2, assesses the functional and socio-economic status of patients who were operated on for a severe limb injury resulting in amputation or limb preservation 1 and 2 years after the 2010 Haiti…
- Trial name
- SuTra² (NCT01779011)
- Where
- Haiti
- Volunteers
- 305 people
- Sponsor
- Alliance for International Medical Action
Childhood Apraxia of Speech
Treatment of Cantonese Speakers With Childhood Apraxia of Speech
The proposed study aims to investigate the efficacy of the Dynamic Temporal and Tactile Cueing treatment in Cantonese-English bilingual speakers with childhood apraxia of speech.
- Trial name
- NCT06385470
- Testing
- Dynamic Temporal and Tactile Cueing treatment
- Where
- Hong Kong
- Volunteers
- 4 people
- Sponsor
- The Hong Kong Polytechnic University
Childhood Apraxia of Speech
The Effects of Caregiver Training on DTTC Treatment Outcomes in CAS
The goal of this clinical trial is to investigate the impact of direct vs. indirect caregiver training on treatment outcomes following a period of Dynamic Temporal and Tactile Cueing (DTTC) intervention combined with home…
- Trial name
- DTTC (NCT05916222)
- Testing
- Dynamic Temporal and Tactile Cueing (DTTC)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- New York University
Congenital Heart Disease
Autus Valve Continued Access Study (CAS)
Prospective, single-arm, multi-center, continued access study of the Autus Size-Adjustable Valve in pediatric patients aged 18 months to 16 years requiring surgical pulmonary valve replacement.
- Trial name
- NCT07466745
- Testing
- Pulmonary Valve Replacement Surgery
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Edwards Lifesciences
Childhood Apraxia of Speech
Childhood Apraxia of Speech: Experience Dependent Changes Induced by Treatment
Childhood Apraxia of Speech (CAS) is a severe speech-language disorder whose aetiological, neuroanatomical correlates are largely unknown.
- Trial name
- CAS (NCT04832503)
- Testing
- PROMPT- treatment, LNSOM-treatment
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- IRCCS Fondazione Stella Maris
Childhood Apraxia of Speech, Verbal Apraxia
Role of Omega-DEK in Childhood Apraxia of Speech
This is a 20-week study for children between 3 and 6 years old with confirmed childhood apraxia of speech (CAS). The study includes a 12-week open-label pilot feasibility study of an investigational drug (Omega-DEK) plus…
- Conditions
- Childhood Apraxia of Speech, Verbal Apraxia, Autism
- Trial name
- NCT07216001
- Testing
- Omega-DEK, L-carnitine
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Claudia R. Morris
Childhood Apraxia of Speech
Methylphenidate in Childhood Apraxia of Speech
The purpose of this study is to describe the possible effects of methylphenidate (MPH) on speech intelligibility in children with childhood apraxia of speech (CAS) aged 6-12 years.
- Trial name
- NCT05185583
- Testing
- Methylphenidate Hydrochloride
- Where
- Australia
- Volunteers
- 18 people
- Sponsor
- Murdoch Childrens Research Institute
Childhood Apraxia of Speech
Dose Frequency RCT on DTTC in Children With CAS
Childhood apraxia of speech (CAS) is a pediatric motor-based speech sound disorder that requires a specialized approach to intervention (Maas et al., 2014).
- Trial name
- NCT05675306
- Testing
- Dynamic Temporal and Tactile Cueing Treatment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Marquette University
Anorexia Nervosa, Attentional Bias
Anorexia Nervosa, Evaluation and MOdification of Attention
Anorexia nervosa (AN), characterized by abnormally low weight, a significant fear of gaining weight, and impaired body perception, is a psychopathological disorder with a 1% prevalence.
- Conditions
- Anorexia Nervosa, Attentional Bias, Psychophysiology, Food
- Trial name
- ANEMA (NCT07861919)
- Testing
- Attentional Bias Modification Training
- Volunteers
- 40 people
- Sponsor
- Lille University
Childhood Apraxia of Speech, Genetic Condition
Speech Therapy for Children With Rare Genetic Conditions and Childhood Apraxia of Speech
The goal of this trial is to learn if speech therapy can improve speech accuracy in children with rare genetic conditions and childhood apraxia of speech (CAS). This study will look at each child individually.
- Trial name
- NCT07815249
- Testing
- Rapid Syllable Transition Treatment, Dynamic Temporal and Tactile Cueing
- Where
- Australia
- Volunteers
- 20 people
- Sponsor
- Murdoch Childrens Research Institute
Childhood Apraxia of Speech
ASSIST: Treatment for Childhood Apraxia of Speech
Childhood apraxia of speech (CAS) is a pediatric motor speech disorder that impairs the planning of movements needed for intelligible speech. Children with CAS often show little or slow progress in standard speech therapy.
- Trial name
- ASSIST (NCT03903120)
- Testing
- ASSIST
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Temple University
Childhood Apraxia of Speech
Rapid Syllable Transition (ReST) Interventions for Speech Sound Disorders in Children
This study will investigate the feasibility of applying the Rapid Syllable Transition Treatment (ReST) protocol in children with Childhood Apraxia of Speech, considering the scarcity of evidence in the context of Brazilian…
- Trial name
- ReST-SSD (NCT07636031)
- Testing
- Rapid Syllable Transition Treatment (ReST)
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Aline Mara de Oliveira
Childhood Apraxia of Speech
A Randomized Control Trial of Motor-based Intervention for CAS
Childhood apraxia of speech (CAS) is a complex, multivariate speech motor disorder characterized by difficulty planning and programming movements of the speech articulators (ASHA, 2007; Ayres, 1985; Campbell et al., 2007; Davis…
- Trial name
- NCT04642053
- Testing
- Dynamic Temporal and Tactile Cuing
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- New York University
Childhood Apraxia of Speech, Speech Sound Disorders
Feasibility and Preliminary Effects of a Therapeutic Approach Using Ultrasound Visual Biofeedback in Children With AFI: a Pilot Randomized Clinical Trial.
The aim of this study is to evaluate the feasibility of the Ultrax protocol and estimate preliminary effects on articulatory precision, prosody, and speech motor planning.
- Trial name
- PICOS (NCT07087249)
- Testing
- Ultrasound Visual Feedback, Waitlist
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Aline Mara de Oliveira
Developmental Verbal Dyspraxia, Autism Spectrum Disorder
Speech Treatment for Minimally Verbal Children With ASD and CAS
Comorbid Childhood Apraxia of Speech (CAS) may be one factor that limits speech development in some minimally verbal children with autism. CAS is a disorder affecting speech movement planning.
- Trial name
- TxMVASD+CAS (NCT05066178)
- Testing
- CAS Treatment for Minimally Verbal Children with Autism
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- MGH Institute of Health Professions
Childhood Apraxia of Speech
Motor-based Intervention for Childhood Apraxia of Speech: DTTC-Connect
Childhood apraxia of speech (CAS) is a complex motor speech disorder that significantly limits a child's ability to communicate in daily activities, with difficulties often persisting into adolescence and adulthood.
- Trial name
- NCT07526246
- Testing
- Dynamic Temporal and Tactile Cueing - Connect (DTTC-Connect)
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- New York University