Clinical trials: Cancer-Associated Pain
Cancer
Treating Pain in Children With Cancer: Pain Buddy
The purpose of this study is to examine the feasibility of the ambulatory monitoring protocol, called Pain Buddy, in documenting children's pain, symptoms and quality of life while receiving outpatient chemotherapy.
- Trial name
- NCT03384134
- Testing
- Pain Buddy
- Where
- United States
- Volunteers
- 407 people
- Sponsor
- University of California, Irvine
Advanced Biliary Tract Cancer(BTC), Advanced Pancreatic Cancers
A Prospective Observational Study of First-Line Systemic Therapy Combined With Celiac Plexus Blockade for Advanced Biliopancreatic Cancer With Pain
This study is for patients with advanced bile duct or pancreatic cancer who are experiencing pain from their disease. The purpose of this research is to learn about the effects of combining a standard pain relief treatment…
- Conditions
- Advanced Biliary Tract Cancer(BTC), Advanced Pancreatic Cancers, Cancer-related Pain
- Trial name
- NCT07326137
- Testing
- First-Line Systemic Therapy, Celiac Plexus Neurolysis (CPN)
- Where
- China
- Volunteers
- 103 people
- Sponsor
- Tongji Hospital
Sarcoma, Childhood Sarcoma of Soft Tissue
Brief Title Mechanisms of Cancer-Related Pain and Opioid Use Among Adolescents and Young Adult Sarcoma Survivors: Pilot Feasibility Study
This study generates information on the feasibility and acceptability of a 3-month ecological momentary assessment (EMA) protocol to assess chronic pain and opioid use in adolescent and young adult (AYA) sarcoma survivors.
- Trial name
- NCT07402577
- Testing
- Non Intervention Study
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Roswell Park Cancer Institute
Oncology Pain
Virtual Reality for Port-a-Cath Access
Children with cancer almost universally receive port-a-catheters (ports) to deliver medication, fluids, blood products, and conduct blood tests. Port access requires a needle inserted through the skin to the subcutaneous tissue.
- Trial name
- NCT04931745
- Testing
- Virtual reality, Tables distraction, No or non-technologic distraction
- Where
- Canada
- Volunteers
- 84 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Systemic Juvenile Idiopathic Arthritis, Hereditary Periodic Fevers
A Study of Canakinumab in Patients With Systemic Juvenile Idiopathic Arthritis or Hereditary Periodic Fevers Who Participated in the CACZ885G2301E1, CACZ885G2306 or CACZ885N2301 Studies
The objective of this extension protocol is to collect safety data (serious and non-serious adverse events) and to provide continuous canakinumab to patients in France who completed study CACZ885G2301E1(NCT00891046), CACZ885G2306…
- Trial name
- NCT02334748
- Testing
- canakinumab
- Where
- 3 sites in France
- Volunteers
- 31 people
- Sponsor
- Novartis Pharmaceuticals
Breast Cancer, Musculoskeletal Complications
S1202: Duloxetine Hydrochloride for Muscle/Joint Pain in Early-Stage Breast Cancer Receiving Hormone Therapy
RATIONALE: Duloxetine hydrochloride may lessen muscle, bone, and joint pain caused by hormone therapy. It is not yet known whether duloxetine hydrochloride is more effective than a placebo in treating patients with muscle, bone…
- Conditions
- Breast Cancer, Musculoskeletal Complications, Pain
- Trial name
- NCT01598298
- Testing
- duloxetine hydrochloride
- Where
- 714 sites in United States
- Volunteers
- 299 people
- Sponsor
- SWOG Cancer Research Network
Pancreatic Neoplasms, Pain
Acupuncture For Pancreatic Cancer Pain
Pain is a common problem in patients with pancreatic cancer. Some patients suffer from pain despite medication. We, the researchers at Memorial Sloan-Kettering Cancer Center, are conducting a Phase III study to determine the…
- Trial name
- NCT00136669
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Neoplasm Metastasis, Pain
Volumetric Intensity Modulated Arc Therapy vs. Conventional Radiotherapy for Cancer Pain
This study compares the use of conventional radiotherapy technique with volumetric intensity-modulated radiotherapy (VMAT) in the treatment of painful cancer metastases.
- Conditions
- Neoplasm Metastasis, Pain, Radiotherapy Side Effect, Quality of Life
- Trial name
- NCT03374592
- Testing
- Volumetric Intensity-Modulated Arc Therapy, Conventional Radiotherapy
- Volunteers
- 73 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pediatric Oncology
The Effects of Nonpharmacological Methods Used in Subcutaneous Application on Pain, Anxiety, and Fear Levels in Children
Childhood cancers are increasing globally and require long-term invasive treatments, particularly subcutaneous applications that often cause pain, swelling, and anxiety.
- Trial name
- NCT07163104
- Testing
- Kaleidoscope, Buzzy, Cognitive behavioral intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Zubeyde Ezgi Ercelik
Malignancy, Pain
Real-time Cancer Pain Assessment and Intervention
This study aim at the advanced malignant tumor patients who suffer from cancer pain, investigate the current status of cancer pain treatment, and study the effects in pain control and quality of life improvement using the method…
- Trial name
- NCT01914107
- Testing
- real-time monitoring and instruction of cancer pain, standard cancer pain care
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Sun Yat-sen University
Gynaecomastia, Prostate Cancer
Casodex - Nolvadex Combination
This study looks at the relationship in the dose of nolvadex and the incidence of gynaecomastia and also Prostate Specific Antigen (PSA) inhibition when co-administered with Casodex.
- Trial name
- NCT00637871
- Testing
- Casodex, Tamoxifen
- Sponsor
- AstraZeneca
Acute Ankle Sprain
Efficacy and Safety of SST 0225, a Topical Ibuprofen Cream, in the Treatment of Pain Associated With Acute Ankle Sprain
This is a randomized, multi-center, double-blind, placebo-controlled, multi-dose, parallel-group study. Approximately 300 subjects (150 per group) 16 years of age and older with a current (within 24 hours from Visit 1) Grade I or…
- Trial name
- NCT01874626
- Testing
- SST-0225 Topical Ibuprofen Cream
- Where
- United States
- Volunteers
- 305 people
- Sponsor
- Strategic Science & Technologies, LLC
Advanced Solid Tumors, Advanced Solid Tumors Cancer
ET-SPACE Whole-Body Infrared Hyperthermia in Patients With Advanced Solid Tumors
This ambispective observational cohort study will evaluate biological changes, palliative outcomes, and safety associated with ET-SPACE whole-body infrared hyperthermia in patients with advanced solid tumors.
- Trial name
- HEAIS-009 (NCT07793214)
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Zhejiang Hospital
Virtual Reality, Pediatric ALL
Virtual Reality in the Management of Pain in Pediatrics: a Multi-center Randomized Clinical Trial (RealPED)
The goal of this clinical trial is to test if the use of virtual reality glasses reduces the pain and anxiety that children feel when they perform a blood test.
- Conditions
- Virtual Reality, Pediatric ALL, Pain, Procedural
- Trial name
- RealPED (NCT05902585)
- Testing
- Virtual reality
- Where
- 6 sites in Spain
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Therapy-Associated Cancer
PainSquad+: A Smartphone App to Support Real-time Pain Management for Adolescents With Cancer
Adolescents with cancer (AWC) are in a unique developmental stage that may mean pain characteristics, the impact of pain, and pain treatment outcomes are different in adolescents compared to children and adults.
- Trial name
- NCT02901834
- Volunteers
- 40 people
- Sponsor
- The Hospital for Sick Children
Breast Cancer
Impact of a Food Supplement on Musculoskeletal Pain in Women With Breast Cancer Treated With Aromatase Inhibitors.
The aim of this pilot study is to assess the change in pain, measured with the Modified Brief Pain Inventory - Short Form (mBPI-sf), at 4, 8, and 12 weeks.
- Trial name
- DOLFLEX (NCT07199556)
- Testing
- Food supplement
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Arafarma Group, S.A.
Cancer Pain
A Randomized Controlled Trial of a Web-based Platform for Cancer Pain Management
Malignant tumors are one of the major public health problems in China, and cancer pain is a common symptom in tumor patients, affecting the quality of life.
- Trial name
- NCT06663956
- Testing
- a patient self-reporting applet
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Pancreatic Cancer Pain
EUS Guided Celiac Neurolysis
Hypothesis: Direct CGN enhances neurolytic drug delivery into celiac ganglia and increases the efficacy of neurolysis and subsequent pain control and survival in patients with pancreatic carcinoma.
- Trial name
- NCT01615653
- Testing
- EUS
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Mayo Clinic