Clinical trials: Chronic Wound
Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE), Juvenile Dermatomyositis (JDM)
Compassionate Use Protocol for the Treatment of Autoinflammatory Syndromes
The Requesting Physician/Investigator contacts Lilly when, based on their medical opinion, a patient meets the criteria for inclusion in the expanded access program.
- Conditions
- Chronic Atypical Neutrophilic Dermatosis With Lipodystrophy and Elevated Temperature (CANDLE), Juvenile Dermatomyositis (JDM), Stimulator of Interferon Genes (STING)-Associated Vasculopathy With Onset During Infancy (SAVI), Aicardi-Goutières Syndrome (AGS)
- Trial name
- NCT01724580
- Testing
- Baricitinib
- Where
- 3 sites in United States, United Kingdom
- Sponsor
- Eli Lilly and Company
Cerebral Palsy, Traumatic Brain Injury
Hybrid Approach to Pediatric Rehabilitation
Children and youth recovering from acquired injuries typically receive therapy via in-patient or outpatient rehabilitation (OPR).
- Conditions
- Cerebral Palsy, Traumatic Brain Injury, Orthopedic Disorder
- Trial name
- NCT06547762
- Testing
- Hybrid approach (in-person and remote) to pediatric rehabilitation: A look beyond the COVID-19 crisis
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Alyn Pediatric & Adolescent Rehabilitation Hospital
Acute Kidney Injury, Chronic Kidney Disease
Long Term Impact of Pediatric Acute Renal Injury in Severe Sepsis
Sepsis is the most common cause of childhood death worldwide. Millions of children survive, but are left with impaired health. Sepsis-related Acute Kidney Injury (sAKI) is increasingly recognized as a significant factor…
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease, Hypertension
- Trial name
- IMPRESS (NCT02372721)
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Florida
Chronic Pain
Peculiarities of Pain in Patients With Gunshot Wounds Depending on the Localization of the Wound at the Stages of Treatment
Chronic pain, in turn, is associated with a whole cohort of mutually aggravating factors - this can lead to the development of extremely serious long-term consequences.
- Trial name
- PPPGWDL (NCT05489029)
- Testing
- visual analog scale
- Where
- Ukraine
- Volunteers
- 1,555 people
- Sponsor
- Bogomolets National Medical University
Hemiparesis, Cerebral Palsy
VR Error Augmentation for Bimanual Task Exercise
This project is a continuing study from the FEATHERS project (NCT02290353) which focuses on developing novel home therapy program for persons with hemiparesis.
- Conditions
- Hemiparesis, Cerebral Palsy, Acquired Brain Injury
- Trial name
- FEATHERSv2 (NCT03766711)
- Testing
- Physical Therapy
- Where
- 2 sites in Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Rotator Cuff Tendinosis
Effects of Rotator Cuff Drills Versus Progressive Resistance Exercises on Chronic Rotator Cuff Tendinopathy
A single-blinded randomized clinical trial was conducted with 30 male overhead athletes (17-35 years) recruited from cricket clubs and sports complexes in Faisalabad.
- Trial name
- NCT07726030
- Testing
- Rotator cuff Drills, Progressive resistance exercises
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Sickle Cell Disease, Kidney Injury
Acute Kidney Injury in Patients With Sickle Cell Disease
Patients with sickle cell disease may be at risk for acute kidney injury (AKI)during sickle cell crisis (pain or acute chest syndrome).
- Conditions
- Sickle Cell Disease, Kidney Injury, Kidney Diseases, Kidney Disease, Chronic
- Trial name
- NCT03105271
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Chronic Ankle Instability, Ankle Sprains
A Study Investigating The Effects Of An Ankle Rehabilitation Program On High School Athletes With Ankle Instability
A randomized controlled trial investigating the effects of a 4-week ankle rehabilitation program on high school athletes with chronic ankle instability.
- Conditions
- Chronic Ankle Instability, Ankle Sprains, Ankle Rehabilitation
- Trial name
- NCT03447652
- Testing
- Resistance Band Ankle Rehabilitation, Biomechanical Ankle Platform System Rehabilitation, Combination Rehabilitation
- Where
- 7 sites in United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Georgia State University
Sequelae of; Infection, Post Infection Glomerulonephritis
Recovering Damaged Cells for Sequelae Caused by COVID-19, SARS-CoV-2
Post-acute sequelae of SARS-CoV-2 infection can cause multiple system function disorders, and complicated symptoms last for an extended period.
- Conditions
- Sequelae of; Infection, Post Infection Glomerulonephritis, Post-Infectious Peripheral Neuralgia, Post-Infectious Disorder (Disorder)
- Trial name
- sequelae (NCT04846010)
- Testing
- PurWet, FurFat, PurApo
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- All Natural Medicine Clinic, LLC
Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity
A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants
The purpose of this study is to determine if an investigational drug can prevent Bronchopulmonary Dysplasia, reducing the burden of chronic lung disease in extremely premature infants, as compared to extremely premature infants…
- Conditions
- Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity, Intraventricular Hemorrhage, Retinopathy of Prematurity (ROP)
- Trial name
- NCT03253263
- Testing
- OHB-607
- Where
- 62 sites in United States, Australia and 11 more
- Volunteers
- 295 people
- Sponsor
- OHB Neonatology Ltd.
Deficits, Neurologic, Extreme Prematurity
SafeBoosC III Two-year Follow-up
The SafeBoosC-III 2 year follow up study will follow up on all patients randomised in the SafeBoosC-III clinical trial (NCT03770741).
- Conditions
- Deficits, Neurologic, Extreme Prematurity, Brain Damage
- Trial name
- NCT05134116
- Testing
- Treatment as usual + cerebral oximetry monitoring the first 72 hours of life
- Where
- Denmark
- Volunteers
- 1,601 people
- Sponsor
- Gorm Greisen
Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament
Comparison of Three Methods for Anterior Cruciate Ligament Reconstruction
The purpose of this randomized clinical trial is to determine the difference in quality of life outcome at two years, in patients undergoing an Anterior Cruciate Ligament (ACL) reconstruction procedure with either a patellar…
- Conditions
- Anterior Cruciate Ligament Rupture, Deficiency of Anterior Cruciate Ligament, Chronic Instability of Knee, Anterior Cruciate Ligament Injury
- Trial name
- NCT00529958
- Testing
- Patellar Tendon, Hamstring Tendon, Double-Bundle
- Where
- Canada
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Cerebral Palsy, Children With Brain Injury
The Effect of Digital Rehabilitation System With Wearable Multi-IMU (Inertial Measurement Unit) Sensors on Upper Limb Functions in Children With Brain Injury
This study was designed to establish the clinical evidence for effect of video-game based rehabilitation therapy system using IMU sensors as a game interface, newly-developed in Korea, on upper limb function of children with…
- Trial name
- NCT02949817
- Testing
- digital rehabilitation system with wearable multi-IMU(inertial measurement unit) sensors (Rapael kids), Conventional OT group
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Epidermolysis Bullosa (EB), Chronic Wounds
Topical Insulin Versus Irradiated Amniotic Fluid Gel for Wound Healing in Epidermolysis Bullosa
This study aims to evaluate and compare the safety and efficacy of topical insulin and topical irradiated amniotic fluid gel in promoting wound healing in patients with epidermolysis bullosa (EB).
- Conditions
- Epidermolysis Bullosa (EB), Chronic Wounds, Wound Healing
- Trial name
- EB-INS-AFG (NCT07907523)
- Testing
- Topical Insulin (Actrapid®), Topical Irradiated Amniotic Fluid Gel, No active study treatment
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Acquired Brain Injury, Cognitive Symptom
CBCR for Executive Functions in Patients With ABI in the Chronic Phase
This study examines the effects of computerbased cognitive rehabilitation on executive functions in the chronic phase after acquired brain injury
- Conditions
- Acquired Brain Injury, Cognitive Symptom, Executive Dysfunction
- Trial name
- NCT03558308
- Testing
- Computer based cognitive rehabilitation
- Where
- Denmark
- Volunteers
- 72 people
- Sponsor
- Katrine Sværke
Renal Transplant, Renin-Angiotensin System
Renal Transplant Injury and the Renin-Angiotensin System in Kids (RETASK)
In pediatric kidney transplant patients, rejection, medication toxicity and ischemia cause early and chronic renal allograft injury, which reduces graft lifespan and patient survival.
- Conditions
- Renal Transplant, Renin-Angiotensin System, Rejection Acute Renal, Rejection Chronic Renal
- Trial name
- RETASK (NCT03317925)
- Testing
- Renal Transplantation
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Wake Forest University Health Sciences
End Stage Renal Disease (ESRD), End Stage Renal Disease on Dialysis
EXtension of Tablo TrEatmeNt Duration Registry
Observational, retrospective and prospective, multicenter, post-market study of the Tablo Hemodialysis System in hospitalized participants with End-Stage Kidney Disease or Acute Kidney Injury who are prescribed renal replacement…
- Conditions
- End Stage Renal Disease (ESRD), End Stage Renal Disease on Dialysis, Acute Kidney Injury
- Trial name
- XTEND (NCT04912050)
- Testing
- Tablo Hemodialysis System
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Outset Medical
Wounds
A Post-marketing Observational Study of Cell Therapy for Chronic Wounds
A post-marketing multi-center observational study to provide data describing the safety and effectiveness of CUREXCELL™ as it is applied in a real-life setting for treatment in patients with chronic and/or refractory wounds.
- Trial name
- NCT01038986
- Testing
- CureXcell
- Where
- 3 sites in Israel
- Volunteers
- 70 people
- Sponsor
- Macrocure Ltd.
Spastic Cerebral Palsy, Acquired Brain Injury
Evaluation of Macroscopic Muscle Growth in Infants and Young Children With Spastic Cerebral Palsy
A mixed longitudinal design study will be carried out to explore the onset and time course of morphological muscle changes on a macroscopic level in children with spastic cerebral palsy (SCP).
- Trial name
- 3D-MMAP (NCT05197764)
- Where
- Belgium
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Spinal Cord Injury Cervical
Noninvasive Spinal Stimulation to Restore Hand Function in Children With Spinal Cord Injury
The main goal of this pilot study is to find the best ways to use transcutaneous spinal cord stimulation (scTS) to improve hand function in children with spinal cord injuries (SCI).
- Trial name
- NCT06489106
- Testing
- Activity based upper extremity training with and without stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Louisville