Clinical trials: Development Disorders
Postpartum Depression
The Effect of Early Dyadic Psychotherapy for Mothers Suffering From PPD on Oxytocin Level and on Childrens' Emotional Development
Background: Postpartum depression follows approximately 10-15% of deliveries. Maternal functional disability, particularly in the relationship with the infant, a hallmark of PPD, causes impairment in the mother's ability to bond…
- Trial name
- NCT04138368
- Testing
- dyadic psychotherapeutic intervention, supportive intervention
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- HaEmek Medical Center, Israel
Neurodevelopmental Disorders, Autism Spectrum Disorder
Patterns of Neurodevelopmental Disorders
The purpose of this study is to systematically evaluate the results of medical investigations to identify symptom and biological patterns and common etiologies of neurodevelopmental disorders.
- Conditions
- Neurodevelopmental Disorders, Autism Spectrum Disorder, Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infection, Pediatric Acute-Onset Neuropsychiatric Syndrome
- Trial name
- NCT06213090
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Richard Frye
Myopia, Accommodation Spasm
Effect of VR and Accommdation Relax on Controlling Myopia in Children
This study evaluates the effect of virtual reality and accommodation relax technique on controlling onset and development of myopia in school-aged children.
- Conditions
- Myopia, Accommodation Spasm, Children
- Trial name
- NCT03427697
- Testing
- Virtual reality and accommodation relax techniques in combination
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Beijing Tongren Hospital
Funnel Chest, Excavatum, Pectus
Cryoanalgesia to Prevent Acute and Chronic Pain Following Nuss Procedure
This Study study compared standard therapy (multimodal and regional analgesia) versus a novel approach (Cryoanalgesia combined with bilateral erector spine plane block and multimodal analgesia) in subjects undergoing minimal…
- Trial name
- NCT05570097
- Testing
- intercostal nerves cryoanalgesia
- Where
- Poland
- Volunteers
- 40 people
- Sponsor
- Pomeranian Medical University Szczecin
Child Development, Denial (Psychology)
Outcome of Children Born After Pregnancy Denial
The objective of this study is to evaluate the impact of denial pregnancy on children's health ( anthropometric data, psychomotor development , disease) at different age of evaluation ( at birth, 9 months, 24 months and between 2…
- Conditions
- Child Development, Denial (Psychology), Disease, Personality Development
- Trial name
- DENIGRO (NCT03295123)
- Testing
- phone interview with the mother
- Where
- France
- Volunteers
- 41 people
- Sponsor
- Central Hospital, Nancy, France
Attention Deficit Hyperactivity Disorder
Effects of Attention Training on Children
Using a double-blind, randomized controlled design to investigate the therapeutic effects of interactive attention training for children with Attention Deficit Hyperactivity Disorder who are receiving conventional rehabilitation…
- Trial name
- NCT04375059
- Testing
- using interactive attention training system
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University
Type 1 Diabetes Mellitus
Exercise Training Intervention in Children With Type 1 Diabetes
Type 1 diabetes mellitus (T1DM) is associated with multiple co-morbidities, such as hypertension, dyslipidemia, coronary heart disease and osteoporosis. The foundation of these conditions lays in childhood.
- Trial name
- Diabex (NCT01220479)
- Testing
- Exercise training program
- Where
- Switzerland
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Developmental Dislocation of the Hip, Reduction Deformity of Limb
Closed Reduction With Anesthesia and no Anesthesia for Developmental Dislocation of the Hip < 6 Months
The purpose of this study is to compare the efficacy of closed reduction with anesthesia and no anesthesia for developmental dislocation of the hip < 6 months
- Trial name
- NCT03096470
- Testing
- anesthesia
- Volunteers
- 30 people
- Sponsor
- The Fuzhou No 2 Hospital
Alpha Mannosidosis
The Natural History of Alpha-Mannosidosis
The natural history study of the rare lysosomal disease alpha-mannosidosis will answer the question; why the rare disease develops as it does?
- Trial name
- HUE-MAN (NCT00498420)
- Where
- 4 sites in Czechia, Germany and 2 more
- Volunteers
- 45 people
- Sponsor
- Zymenex A/S
Autism Spectrum Disorder
A Trial of Project ImPACT in Early Intervention
Our pilot study will address a number of pressing questions, including: Can community clinicians successfully coach parents of children with ASD in evidence-based practice to achieve positive outcomes for their children and…
- Trial name
- NCT04729127
- Testing
- Project ImPACT
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- University of Pennsylvania
Malocclusion, Angle Class II
Dentoskeletal Changes Associated With Herbst Appliance Therapy
The aim of the study is to perform a three-dimensional (3D) evaluation of the dentoskeletal changes in pubertal Class II malocclusion subjects treated with the Herbst appliance (HAG), in comparison with a Class II comparison…
- Trial name
- NCT02456220
- Testing
- Herbst appliance
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Bernardo Quiroga Souki
Nutritional Anemia, Nutritional Deficiency
Nutrition Intervention to Address Anemia Among Adolescent Girls in Liberia
The purpose of this study is to evaluate the feasibility and effectiveness of weekly iron and folic acid (IFA) supplementation and one-time deworming treatment at the community level in improving hemoglobin levels among…
- Conditions
- Nutritional Anemia, Nutritional Deficiency, Iron Deficiency Anemia Treatment, Folic Acid Deficiency Anemia, Dietary
- Trial name
- NCT05073562
- Testing
- Iron and folic acid (IFA) supplementation, Targeted nutrition education, Mebendazole Pill
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Pediatric Obesity
A National School-based Health Lifestyles Interventions Among Chinese Children and Adolescents Against Obesity
The study was designed as a national multi-centered cluster randomized controlled trial involving more than 70,000 children and adolescents aged 7-18 years from 7 provinces in China.
- Trial name
- NCT02343588
- Testing
- The Health Lifestyles Interventions
- Volunteers
- 70,000 people
- Sponsor
- Sun Yat-sen University
Child, Only, Metabolic Diseases
Nutritional Study in Spanish Pediatric Population
This study investigates the aspects related to the intake of food and nutrients, physical activity and sedentary behavior of Spanish children from 1 to 9 years.
- Conditions
- Child, Only, Metabolic Diseases, Child Development, Diet Habit
- Trial name
- EsNuPI (NCT03941392)
- Where
- Spain
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Fundacion Iberoamericana de Nutricion
Osteogenesis Imperfecta
Osteogenesis Imperfecta and Balance
Osteogenesis Imperfecta (OI), also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It results in bones that break easily. Its severity may be mild to severe.
- Trial name
- NCT06010134
- Testing
- Physical Therapy Program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- South Valley University
Premature
Feasibility Study of SPEEDI
The proposed feasibility study will evaluate the investigators ability to conduct a clinical trial of a novel intervention (SPEEDI) which addresses a striking gap in the literature.
- Trial name
- SPEEDI (NCT01889108)
- Testing
- SPEEDI
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University
Autistic Disorder
A Controlled Study of Olanzapine in Children With Autism
This is a 12-week study which investigates the use of olanzapine to decrease disruptive behaviors sometimes associated with Autism in children, aged 3 to 12 years old.
- Trial name
- NCT00057408
- Testing
- olanzapine (Zyprexa)
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- FDA Office of Orphan Products Development
Global Developmental Delay
Umbilical Cord Blood Therapy for Global Developmental Delay
This open-label study aims to evaluate the safety and efficacy of autologous or allogeneic umbilical cord blood therapy for children with global developmental delay.
- Trial name
- NCT01769716
- Testing
- Umbilical cord blood transplantation
- Where
- South Korea
- Volunteers
- 14 people
- Sponsor
- MinYoung Kim, M.D.
Molar Hypomineralization, Incisor
Resin Infiltration vs Ionomer-Based Fluoride Varnish for the Prevention of Post-Eruptive Breakdown in Molars With Mild MIH
round/Objective: The objective of this clinical trial is to evaluate the clinical efficacy of a resin infiltrant (Icon®, DMG) compared to an ionomer-based fluoride varnish (Clinpro XT®, 3M) in preventing post-eruptive enamel…
- Trial name
- MIH (NCT07443878)
- Testing
- Resin Infiltrant (Icon®, DMG), Varnish-Modified Glass Ionomer (Clinpro XT®, 3M)
- Where
- Mexico
- Volunteers
- 17 people
- Sponsor
- Universidad Autonoma de San Luis Potosí
Blood Coagulation Disorders
Study of Megakaryocytes From Patients With Abnormal Platelet Vesicles
Congenital bleeding disorders characterized by abnormal platelet granules include Gray Platelet syndrome (GPS; defective alpha-granules), Hermansky-Pudlak syndrome (HPS; defective delta-granules), and combined alpha delta-storage…
- Trial name
- NCT00086476
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- National Human Genome Research Institute (NHGRI)
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