Clinical trials: Extremity
Neuropathy;Peripheral, Limb Ischemia
Feasibility and Clinical Utility of Paired Non-Invasive Hemodynamic and Tissue Oximetry Monitoring to Detect Limb Ischemia in Lithotomy-Positioned Surgeries
The LIMB Study is a prospective, observational pilot study evaluating the feasibility of combined non-invasive hemodynamic and lower-limb tissue oximetry monitoring during prolonged minimally invasive pelvic surgeries performed…
- Trial name
- LIMB (NCT07387653)
- Testing
- Lower-Extremity Perfusion Monitoring
- Where
- 2 sites in United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Syndactyly
Comparison of Scar Formation in Syndactyly Release Surgery With Full Thickness Skin Graft Versus Skin Graft Substitute
Syndactyly is the most common hand abnormality in children. During development, two or more fingers do not separate in the usual way and remain connected by skin. Surgery is needed to separate the fingers.
- Trial name
- NCT03107546
- Testing
- Hyalomatrix, Skin graft
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Gillette Children's Specialty Healthcare
Cerebral Palsy (CP)
Feasibility of the Trunk and Upper Extremity Assessments for Teleassessment in Children Cerebral Palsy
This study was conducted to investigate the suitability of trunk and upper extremity assessments used within the scope of the ICF for tele-assessment in children with hemiplegic cerebral palsy (CP).
- Trial name
- NCT06707831
- Testing
- Teleassessment
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Hacettepe University
Upper Limb Fracture
Biobased Polyester Versus Synthetic Fiberglass Casts for Treating Stable Upper Limb Fractures in Children
From Feb 2022 to Nov 2022, we undertook a single-center prospective randomized trial involving 100 children with cast-immobilized stable upper limb fractures.
- Trial name
- NCT06102603
- Testing
- the biobased polyester cast, the synthetic fiberglass cast
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Far Eastern Memorial Hospital
Parkinson Disease
Effect of a Boxing Program on People With Parkinson Disease
This study is investigating the impact of a boxing training program on people with Parkinson Disease. The investigators were provided data for the intervention group retrospectively by the organizers of the boxing club to assess…
- Trial name
- NCT04781842
- Testing
- Boxing exercise program
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Husson University
Scapular Muscle Endurance, Adolescent
Validity and Reliability of the Scapular Muscular Endurance Test
The scapula plays a crucial role in proper shoulder function, contributing to synchronized scapular rotation during humeral motion, serving as a stable base for rotator cuff activation, and acting as a key link in the kinetic…
- Trial name
- NCT06846242
- Testing
- Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 67 people
- Sponsor
- Istinye University
Eccentric Exercise Training, Strength Training Effects
Elastic Band Exercise to Improve Hip Strength and Agility in Young Basketball Players
Here is the complete Brief Summary entry in a single paragraph, written in plain language, and excluding the study results (as requested), but maintaining academic rigor in describing the study design: The purpose of this study…
- Conditions
- Eccentric Exercise Training, Strength Training Effects, Strengthening Exercises, Hip Adduction Strength
- Trial name
- NCT07421986
- Testing
- Eccentric Hip Adductor Strengthening with Elastic Bands
- Where
- Serbia
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Nebojša Trajković
Cerebral Palsy
Effects of Stationary Cycling and Progressive Functional Training in Cerebral Palsy Children
Cerebral palsy is not a progressive disease but movement problem and musculoskeletal disorders in cerebral palsy change with time.
- Trial name
- NCT06198153
- Testing
- Stationary Cycling, Progressive Functional Training
- Where
- Pakistan
- Volunteers
- 22 people
- Sponsor
- Riphah International University
Sleep Disorder, Restless Legs Syndrome
Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder
The purpose of this research study is to see if the level of serum ferritin differs based on how often oral iron (in the form of ferrous sulfate) is given to children with restless leg syndrome/periodic limb movement disorder.
- Conditions
- Sleep Disorder, Restless Legs Syndrome, Periodic Limb Movement Sleep Disorder, Iron-deficiency
- Trial name
- NCT04610827
- Testing
- Ferrous sulfate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
LGMD
Evaluating Safety and Efficacy of Autologous Gene-edited Muscle Stem Cells (GenPHSats-bASKet)
This study is an investigator initiated first-in-human interventional open label phase 1/2a clinical trial investigating an ATMP in the orphan disease LGMD to evaluate safety and efficacy.
- Trial name
- NCT05588401
- Testing
- GenPHSat injection (Safety), GenPHSat injection (Efficacy), Muscle Biopsy (Safety)
- Volunteers
- 6 people
- Sponsor
- Simone Spuler, MD
Diplegic Spastic Cerebral Palsy
Effects OF NMES With and Without Dynamic Bracing on Spasticity and Movement Quality in CP
The study aims at comparing Neuromuscular electrical Stimulation with and without dynamic bracing on spasticity and movement quality of lower limb in Children with Cerebral Palsy
- Trial name
- NCT06303336
- Testing
- NMES with Dynamic Bracing, NMES without Dynamic Bracing, Dynamic Bracing Only
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Riphah International University
Cerebral Palsy
Effects of Dynamic Compression Garments in Children With CP
In recent years, it is seen that dynamic compression garments are used to increase body stability and to provide tone regulation. Dynamic compression garments are used to apply pressure to specific muscles or muscle groups.
- Trial name
- NCT05592236
- Testing
- Dynamic compression garments, Standard therapy
- Volunteers
- 34 people
- Sponsor
- Istanbul University - Cerrahpasa
Recurrent Clubfoot
A Study on the Treatment of Recurrent Clubfoot With the Tendon Release of Musculi Tibialis Posterior
The musculi tibialis posterior can adduct the foot, so releasing the tedon of the muscle can help to correct the deformity of the forefoot adduction.
- Trial name
- NCT04212663
- Testing
- The tendon release of musculi tibialis posterior, Anterior tibial tendon transfer(TATT), Achilles tendon lengthing
- Volunteers
- 80 people
- Sponsor
- Guangzhou Women and Children's Medical Center
Spastic Cerebral Palsy (sCP)
Virtual Reality Combined With Bobath Therapy for Spastic Cerebral Palsy
Spastic cerebral palsy is a common neurodevelopmental disorder characterized by increased muscle tone, impaired balance, and limitations in motor function, particularly in the lower limbs.
- Trial name
- VR-BOBATH-CP (NCT07392398)
- Testing
- Virtual Reality Combined With Bobath Therapy, Conventional Bobath Therapy
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Tongren Hongxin Kangxin Traditional Chinese Medicine Hospital, Guizhou Province
Surgery
Comparison of Blood Pressure Measurements in Upper and Lower Extremities in Children Under General Anesthesia
There is very little information comparing non-invasive blood pressure (BP) readings obtained from upper and lower limbs, as well as comparing invasive and non-invasive blood pressures in the children under anesthesia.
- Trial name
- NCT03220906
- Testing
- Blood pressure measurement
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Nationwide Children's Hospital
Cerebral Palsy, Stroke
Reliability of the Melbourne Assessment
The aim of the study is to investigate the reliability of the Melbourne Assessment.
- Conditions
- Cerebral Palsy, Stroke, Traumatic Brain Injury, Meningomyelocele
- Trial name
- NCT02595411
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Children's Hospital, Zurich
Hernia, Inguinal, Flat Foot
The Efficacy and Safety of Chloroprocaine 1% and 2% in Pediatric Population
Randomized, multi-center, double-blind, two-armed, parallel active groups, prospective trial to evaluate the efficacy and safety of local anesthetic Chloroprocaine at two different concentrations ( at 1% and 2%) in a pediatric…
- Trial name
- NCT03918798
- Testing
- Chloroprocaine 1% Injectable Solution, Chloroprocaine 2% Injectable Solution
- Where
- 9 sites in Italy, Spain
- Volunteers
- 164 people
- Sponsor
- Sintetica SA
Athletic Performance
Microdosed Versus Conventional Plyometric Training in Adolescent Basketball Players
This randomized controlled trial compared microdosed and conventional plyometric training in adolescent male basketball players.
- Trial name
- NCT07826104
- Testing
- Microdosed Plyometric Training, Conventional Plyometric Training
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Chongqing Normal University
Resectable Soft Tissue Sarcoma, Extremities
Adjuvant Versus Neo-adjuvant Radiotherapy in Patients With Resectable Soft Tissue Sarcoma in Extremities : Wound Complications
Extremity soft tissue sarcomas (ESTS)s are rare mesenchymal cancers that considered a challenge for orthopaedic surgeons. Soft tissue sarcomas (STS) comprise less than 1% of malignant cancers, commonly occur in the proximal…
- Conditions
- Resectable Soft Tissue Sarcoma, Extremities, Radiotherapy Wound Complications
- Trial name
- NCT05442333
- Testing
- surgical resection with safety margin
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Pediatric Obesity, Lower Extremity Biomechanics
Training Induced Reduction of Lower-limb Joint Loads During Locomotion in Obese Children
Childhood obesity is one of the most critical and accelerating health challenges throughout the world. It is a major risk factor for developing varus/valgus misalignments of the knee joint.
- Trial name
- NCT02545764
- Testing
- Strength and neuromuscular exercise programme
- Where
- Austria
- Volunteers
- 48 people
- Sponsor
- St. Pölten University of Applied Sciences
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