Clinical trials: Fertility Issues
Polycystic Ovary Syndrome (PCOS)
Blood Vessel Function in Adolescents and Women With Polycystic Ovary Syndrome
The purpose of this study is to determine if changes in blood vessel health lead to the menstrual irregularities that women with PCOS experience.
- Trial name
- NCT01615562
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Burden, Infertility
Economic and Psychological Burden of Infertility Among Women Attending Women Health Hospital, Assiut University
Rational of the study: Infertility is a significant reproductive health issue for couples worldwide. The effects of infertility are wide-ranging-from mental health issues such as anxiety and depression to social and economic…
- Trial name
- NCT06664086
- Testing
- economic and psychological burden
- Volunteers
- 480 people
- Sponsor
- Assiut University
Infertility
REKOVELLE PEN for S.C. Injection General Drug Use Survey (Controlled Ovarian Stimulation in Assisted Reproductive Technologies)
This survey targets controlled ovarian stimulation with this drug for the development of multiple oocytes in women undergoing assisted reproduction (ART) such as in vitro fertilization (IVF) or intracytoplasmic sperm injection…
- Trial name
- NCT06545877
- Where
- Japan
- Volunteers
- 571 people
- Sponsor
- Ferring Pharmaceuticals
Abnormal Spermatogenesis, Azoospermia
Study of Synapsis and Recombination in Male Meiosis and the Implications in Infertility
The aim of this study was to assess meiotic recombination in primary spermatocytes, synaptonemal complex length and the correlation with chromosomal abnormalities in testicular spermatozoa from infertile men with idiopathic…
- Trial name
- NCT02339272
- Testing
- non interventional
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- Igenomix
Infertility, Female
Letrozole in Clomiphene Resistant Infertile Women With Polycystic Ovarian Syndrome
Polycystic ovary syndrome accounts for the vast majority of anovulatory symptoms and hyperandrogenism in women. The diagnosis of Polycystic ovary syndrome has life-long implications, with increased risk for infertility, metabolic…
- Trial name
- NCT03135301
- Testing
- letrozole plus metformin, letrozole
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Infertility
US Eeva™ Pregnancy Investigational Clinical Study (US EPIC)
The purpose of this clinical investigation is to gather data to evaluate the impact of using Eeva with traditional morphology grading on implantation rates.
- Trial name
- US EPIC (NCT01671657)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Progyny, Inc.
Infertility, Female
CAPA-IVM Versus STANDARD IVM
The aim of this study is to evaluate the effectiveness and safety of CAPA-IVM versus standard IVM in women with polycystic ovarian morphology (PCOM) or polycystic ovary syndrome (PCOS) .
- Trial name
- NCT03921710
- Testing
- CAPA-IVM, Standard-IVM
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Mỹ Đức Hospital
Infertility Assisted Reproductive Technology, Oocyte Retrieval
ART Cycle Outcomes When Only 1 to 3 Oocytes Are Retrieved
This is a monocentric retrospective observational study. The study focuses on the women who underwent Assisted Reproductive Technology (ART) cycles with poor ovarian response (POR), defined as <4 oocytes retrieved.
- Trial name
- POR (NCT06950476)
- Testing
- Oocyte Retrieval
- Volunteers
- 3,761 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Infertility, Infertility, Female
Follicular Fluid Fetuins in in Vitro Fertilization
This study aims to investigate whether follicular fluid concentrations of fetuin A and fetuin B are associated with the clinical pregnancy and live birth rates in in vitro fertilization (IVF) cycles.Twenty-nine women with poor…
- Trial name
- NCT04201847
- Testing
- Serum test
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Samsun Education and Research Hospital
Infertility,Female
Recombinant LH Supplementation Timing Strategies (From Day 1 or Day 6) to a Standard GnRH Agonist Long Protocol in Subsequent COS Cycle of Older Patients With Unexpected Poor or Suboptimal Ovarian Response
A randomized, controlled, pilot study, for Patients ≥ 35 years and < 40 years old with sufficient ovarian reserve parameters (AFC≥ 5), but showed an unexpected poor or suboptimal ovarian response(defined as ≤ 9 retrieved oocytes…
- Trial name
- NCT04178135
- Testing
- rLH
- Where
- 2 sites in China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Infertility, Female, IVF
RCT to Assess the Impact of Microbiome Status in Infertile IVF Patients at Their First IVF/ICSI Cycle
Although the endometrium has been traditionally considered free of bacteria, recent studies have documented the presence of an endometrial microbiome.
- Trial name
- NCT04686357
- Testing
- EMMA/ALICE
- Volunteers
- 1,018 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Cancer, Autoimmune Disorders
Testicular Tissue Cryopreservation for Fertility Preservation
Testicular tissue cryopreservation is an experimental procedure where a young boy's testicular tissue is retrieved and frozen. This technique is reserved for young male patients who are not yet producing mature sperm, with the…
- Trial name
- NCT02972801
- Testing
- Testicular biopsy
- Where
- United States
- Volunteers
- 1,500 people
- Sponsor
- University of Pittsburgh
Rheumatologic Diseases, Ovarian Reserve
Assessment of Ovarian Reserve in Women With Rheumatologic Diseases
Our infertility unit has started a clinic for women with rheumatological diseases. those women are prone to infertility problems and it might be due to their illness or cytotoxic treatment .
- Conditions
- Rheumatologic Diseases, Ovarian Reserve, Infertility
- Trial name
- NCT02273869
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Meir Medical Center
Azoospermia
Testis Needle Aspiration of Sperm in Men With Azoospermia
Needle aspiration of the epididymis causes rupture and irreversible damage to the duct. Recurring punctures and needle aspirations of fluid and tissue during Testicular Fine Needle Aspiration (TEFNA) procedure cause irreparable…
- Trial name
- NCT02418832
- Testing
- Sperm cell aspiration and TEFNA
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Hadassah Medical Organization
Oligospermia, Azoospermia
Genetic Studies Spermatogenic Failure
The proposed study is designed to test the following hypotheses: 1. Mouse autosomal or X-linked genes which are exclusively expressed in mouse spermatogonia are also spermatogonia-specific in human. 2.
- Conditions
- Oligospermia, Azoospermia, Male Infertility
- Trial name
- NCT00548977
- Testing
- Drawing blood to study genetic polymorphism
- Where
- Taiwan
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Infertility
Programming by Estrogen Treatment in Gonadotropin Releasing Hormone Antagonist Protocol
The purpose of this study is to determine if pretreatment with Estrogen can assist in the planning and programming of In Vitro Fertilization treatments.
- Trial name
- NCT01419353
- Testing
- estradiol valerate
- Where
- Israel
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Dysmenorrhea, Metrorrhagia
Cooperative Adenomyosis Network
To set up a Cooperative Network by enrolling 5000 patients with Adenomyosis(AM) from multiple centers.Based on the Network platform and Database,the investigators try to explore the diagnostic strategies for AM and carry out…
- Conditions
- Dysmenorrhea, Metrorrhagia, Infertility, Female, Pathology
- Trial name
- CAN (NCT03230994)
- Where
- China
- Volunteers
- 5,000 people
- Sponsor
- Peking Union Medical College Hospital
Infertility, Female, Pelvic Inflammatory Disease
Effect of Prophylactic Antibiotics for Hysterosalpingography on Post Procedure Morbidity
The study will be a parallel randomised trial. There are two groups. The first group will be given prophylactic antibiotics before a procedure (hysterosalpingography) and the second group will be given a placebo(multivitamin).
- Trial name
- NCT04234945
- Testing
- Doxycycline Capsule, Multivitamins W/Iron Tab
- Where
- Nigeria
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Ahmadu Bello University Teaching Hospital
Female Infertility
The Embryologist's Impact on Blastocyst Vitrification and Thawing
The goal of this monocentric retrospective observational study is to analyse, for the first time in literature, the role of the embryologist who freezes and thaws the embryos.
- Trial name
- NCT06220227
- Testing
- vitrification and thawing procedures
- Where
- Italy
- Volunteers
- 6,800 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
Unexplained Infertility
The Effect of LMWH on ICSI in Patients With Unexplained Infertility and Negative Immunological Markers
The purpose of this study is to assess the efficacy of LMWH treatment in women with unexplained infertility and negative immunological markers undergoing ICSI.
- Trial name
- NCT02861105
- Testing
- LMWH, 0.9% saline solution
- Volunteers
- 716 people
- Sponsor
- Ain Shams University