Clinical trials: Health Care
Critical Illness Recovery, Mental Health
Building Resilience Through Anxiety Virtual Education in PICU Survivors
Survivors of Pediatric Intensive Care Unit (PICU) admissions often experience adverse mental health consequences, either as a result of, or associated with, their intensive care stay.
- Trial name
- BRAVE-PICU (NCT07906366)
- Testing
- Digital Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Rochester
Digital Health, Maternal Health Services
The Effect of Digitally Enabled District (DED 2.0) Ecosystem on the Completeness and Timeliness of Maternal and Neonatal Services in Primary Health Care
DED 2.0 is a stepped-wedge cluster-randomized trial testing whether an integrated digital health ecosystem (KuApps, a service-monitoring dashboard, AI-assisted OCR for handwritten records, two-way WhatsApp-based health…
- Conditions
- Digital Health, Maternal Health Services, Prenatal Care, Intensive Care, Neonatal
- Trial name
- DED (NCT07842224)
- Testing
- Digitally Enabled District (DED)
- Where
- Indonesia
- Volunteers
- 10,800 people, healthy volunteers welcome
- Sponsor
- Summit Institute for Development, Indonesia
Malaria
Factors Influencing Adoption of a Novel Malaria Treatment in Côte d'Ivoire, Ghana, and Rwanda
This non-interventional qualitative study will examine factors that influence the adoption of a novel malaria treatment in Côte d'Ivoire, Ghana, and Rwanda.
- Trial name
- NCT07896746
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Childhood Cancer, Survivorship
A Multilevel Intervention to Improve Adherence to Childhood Cancer Survivorship
More than 80% of childhood cancer survivors develop serious or life-threatening late effects after cancer therapy, but <20% receive recommended survivorship care offered at cancer center survivorship clinics.
- Conditions
- Childhood Cancer, Survivorship, Health Care Utilization, Health Knowledge, Attitudes, Practice
- Trial name
- BRIDGES (NCT05448560)
- Testing
- Multi-level Intervention of shared model of survivorship care, Comparison Group
- Where
- 4 sites in United States
- Volunteers
- 240 people
- Sponsor
- Georgetown University
Acute Care Service Utilization, Mental Health Status
Homeless Veterans and Peer Whole Health Coaching
Use of acute care services (e.g., hospitalizations, Emergency Department visits) contributes substantially to the cost of healthcare for Veterans. Homelessness is a robust social determinant of super utilization of acute care.
- Conditions
- Acute Care Service Utilization, Mental Health Status, Physical Health Status, Housing
- Trial name
- PWHC (NCT05176977)
- Testing
- Peer Support-Whole Health Coaching
- Where
- 3 sites in United States
- Volunteers
- 177 people
- Sponsor
- VA Office of Research and Development
Pregnancy, Post Partum
Deconstructing Maternal Burdens: Doulas and the Community Unite for Health
This study is a randomized controlled trial comparing two models of doula support for pregnant individuals enrolled in Medicaid: an enhanced doula support model, in which support starts earlier in pregnancy, occurs more…
- Conditions
- Pregnancy, Post Partum, Doula Care, Postpartum Depression (PPD)
- Trial name
- UNITE (NCT07799805)
- Testing
- Doula, Standard (non-enhanced) Medicaid doula support
- Where
- United States
- Volunteers
- 516 people
- Sponsor
- University of Florida
Mental Health Care, Mental Health in Elementary School Children
Cognitive-Function Informed Outpatient Child and Youth Mental Healthcare
Cognitive Function Informed Care (CFIC) is a new, add-on type of care for mental health outpatients. To receive this type of care, a child/youth does something called a neuropsychological assessment, which are tests given by a…
- Conditions
- Mental Health Care, Mental Health in Elementary School Children, Mental Health Conditions, Mental Health Difficulties
- Trial name
- CFIC (NCT07842952)
- Testing
- Cognitive Function Informed Care (CFIC), Standard Care (in control arm)
- Where
- Canada
- Volunteers
- 215 people
- Sponsor
- Children's Hospital of Eastern Ontario
Renal Dialysis, Renal Replacement Therapy
Machine Learning and Artificial Intelligence Algorithms to Optimize the Performance and Delivery of Acute Dialysis
SMART DIALYSIS - Scaling Machine Learning and Artificial Intelligence AlgoRithms to OpTimize the Performance and Delivery of Acute DIALYSIS.
- Conditions
- Renal Dialysis, Renal Replacement Therapy, Renal Diseases, Quality Health Care
- Trial name
- SMART DIALYSIS (NCT07312929)
- Testing
- intermittent OR continuous renal replacement therapies
- Where
- 15 sites in Canada
- Volunteers
- 7,500 people
- Sponsor
- University of Alberta
Mental Health Care, AMBIT
My Avenue to helP - Adaptive Mentalization-based Integrative Treatment Compared to Management as Usual for Youths With Multiple Problems: a Non-Randomized Controlled Feasibility Trial
My Avenue to HelP (MAP) is a non-randomized feasibility study testing the implementation of a cross-sectoral collaboration targeted youths, aged 12-17 years, with multiple social and psychological problems.
- Conditions
- Mental Health Care, AMBIT, Adaptive Mentalization-Based Integrative Treatment, Child and Adolescent Psychiatry
- Trial name
- MAP (NCT06886165)
- Testing
- My Avenue to HelP, Management as Usual
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Pia Jeppesen
Maternal Health, Neonatal Health
Improving Maternal and Neonatal Care-seeking Through a Video-informed Training Session During the Third Trimester of Pregnancy
This study is a randomized controlled trial evaluating the impact of a video-informed training session on maternal and newborn health care seeking in rural Côte d'Ivoire.
- Conditions
- Maternal Health, Neonatal Health, Pregnancy, Postpartum Care
- Trial name
- Taabo T3 (NCT07819201)
- Testing
- Information video and planning session
- Where
- Côte d’Ivoire
- Volunteers
- 800 people
- Sponsor
- Swiss Tropical & Public Health Institute
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans
Women Veterans are the fastest growing segment of VA users. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that they will want and be able…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Smoking
- Trial name
- EMPOWER (NCT05050266)
- Testing
- EBQI, REP
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- VA Office of Research and Development
Cardiovascular Diseases (CVD), Cardiovascular Diseases Risk
Cardiovascular Health and Nursing Interventions in 6th Grade Middle School Children
Interventions that can improve cardiovascular health behaviors in children are of critical importance for reducing the burden of cardiovascular disease in the future.
- Conditions
- Cardiovascular Diseases (CVD), Cardiovascular Diseases Risk, Health Behavior, School Health Services
- Trial name
- NCT06812156
- Testing
- Cardiovascular Health Education
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ankara University
Health Care, Pediatrics
Hospital-to-Home Transitional Care Interventions (H2H-TCI) Children/Youth With Special Health Care Needs (CYSHCN)
Aim 1: Compare the effectiveness of focused dose vs extended dose hospital-to-home Transitional Care Interventions (H2H-TCI) on health service use and parent-reported confidence for hospitalized CYSHCN.
- Conditions
- Health Care, Pediatrics, Transitional Care, Comparative Effectiveness
- Trial name
- H2H-CYSHCN (NCT06428175)
- Testing
- Focused Dose Hospital-to-Home Transitional Care Interventions, Extended Dose Hospital-to-Home Transitional Care Interventions
- Where
- 2 sites in United States
- Volunteers
- 480 people
- Sponsor
- Duke University
Neonatal Hypoglycemia, Metabolic Complication
Pasteurised Donor Human Milk Supplementation for Term Babies
PRESENT is a multi-center randomised controlled trial that aims to assess whether access to pasteurized donor human milk as supplementary nutrition in the first five days of life for term infants born to women with diabetes in…
- Conditions
- Neonatal Hypoglycemia, Metabolic Complication, Cows Milk Allergy, Hospital Length of Stay
- Trial name
- PRESENT (NCT06993103)
- Testing
- Standard care Cow's milk based formula, Dietary Supplement: PDHM Pasteurised Donor Human Milk
- Where
- 4 sites in Australia
- Volunteers
- 1,444 people
- Sponsor
- The University of Queensland
Mental Health Care
Evaluation of a Flexible and Integrative Psychiatric Care Model at the Pfalzklinikum (EVA_Pfalz)
This study is an evaluation of the flexible and integrative psychiatric care model (according to § 64b of the German Social Code Book V (SGB V)) (FIT) at the Pfalzklinikum.
- Trial name
- EVA_Pfalz (NCT05181982)
- Testing
- FIT contract with global treatment budget
- Where
- Germany
- Volunteers
- 10,000 people
- Sponsor
- Technische Universität Dresden
Perinatal Depression
Early Detection of Perinatal Depression With Wearable Technology
The goal of this feasibility study is to learn whether wearable devices and self-report surveys can help researchers better understand changes in mood during pregnancy and after birth in young pregnant individuals with a history…
- Trial name
- BLUESMAPPED (NCT07784244)
- Testing
- Oura Ring (Photoplethysmography-based wearable ring), EmbracePlus Watch (Electrodermal activity wristband sensor)
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Women's College Hospital
Cardiovascular Care, Cardiovascular Diseases Health Behavior
Healthy Heart, Healthy Life" Program on Cardiovascular Health Behaviors
This study evaluated the effect of the "Healthy Heart, Healthy Life" education program on the cardiovascular health behaviors of middle school students.
- Trial name
- NCT07781280
- Testing
- EDUCATION
- Where
- Turkey (Türkiye)
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Bilecik Seyh Edebali Universitesi
Self-Help Devices, Long-Term Care
Assistive Device Rental/Purchase, LTC Service Use, and Caregiver Burden in Taiwan
The goal of this observational study is to examine the associations between assistive device approval and acquisition modality (rental or purchase), long-term care service utilization, and family caregiver burden among…
- Conditions
- Self-Help Devices, Long-Term Care, Caregiver Burden, Health Services Research
- Trial name
- NCT07782047
- Where
- Taiwan
- Volunteers
- 161,771 people
- Sponsor
- National Health Research Institutes, Taiwan
Postpartum Complication, Health Care Seeking Behavior
Community Health Worker Assessment for Postpartum Health
The goal of this randomized controlled trial is to compare the CAREPATH intervention with standard of care on postpartum outcomes among up to 500 postpartum individuals.
- Trial name
- CAREPATH (NCT07572604)
- Testing
- CAREPATH, Standard of Care
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Life Style, Health-Related Behavior
A Group Intervention for Promoting Health-related Habits (LEV-G)
Health-related habits influences mental and physical health. Still, treatment of health-related habits, which can help to remedy health problems, is often not done at all or very superficially.
- Conditions
- Life Style, Health-Related Behavior, Disabilities Mental, Disability Physical
- Trial name
- NCT06404632
- Testing
- Lev-g
- Where
- Sweden
- Volunteers
- 30 people
- Sponsor
- Region Stockholm