Clinical trials: Intestinal Fistula
Anorectal Fistula
Retrospective Review of the Cook Biodesign® Fistula Plug to Treat Anorectal Fistulas
The study is a retrospective review of the use of the Biodesign® Fistula Plug (C-FPS-[X]). A total of 73 patients will be enrolled who have had a fistula plug placed to treat anorectal fistulas and will therefore be eligible for…
- Trial name
- NCT03321266
- Testing
- Cook Biodesign® Fistula Plug
- Where
- 4 sites in United States, Germany
- Volunteers
- 79 people
- Sponsor
- Cook Group Incorporated
Fistula in Ano
Role of Udumbara Sutra in the Management of Fistula in Ano a Rare Case Study
The anal fistula is a notorious disease due to its recurrence rate. Bhagandara is varyingly defined as a tear, ulcer or boil at Bhaga (Perianal region) within 2 finger circumference of it, causing painful abscess when opened is…
- Trial name
- Bhagandara (NCT01954225)
- Testing
- Udumbara Sutra
- Where
- India
- Volunteers
- 1 people
- Sponsor
- Government Ayurved College and Hospital
Fistula in Ano, Crohn Disease
Pediatric MSC-AFP Sub-study for Crohn's Fistula
The purpose of this study is to determine the safety of using an autologous mesenchymal stromal cell (MSC) coated fistula plug in people with fistulizing Crohn's disease.
- Trial name
- NCT03449069
- Testing
- MSC-AFP
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mayo Clinic
Crohn Disease, Perianal Fistula
Adipose Tissue in Crohn´s Disease Fistulas
Present study investigated the efficacy of injection of freshly collected autologous adipose tissue into perianal fistulas in patients with Crohn's disease.
- Conditions
- Crohn Disease, Perianal Fistula, Tissue Transplantation
- Trial name
- NCT03803917
- Testing
- Injection with freshly collected autologous adipose tissue
- Volunteers
- 21 people
- Sponsor
- Lilli Lundby
Anal Fistula Surgery, Anal Fistula
The Modified Clipped-LIFT Procedure for High Transsphincteric or Suprasphincteric Fistula
A retrospective analysis was performed on 96 patients who underwent modified LIFT procedures to treat transsphincteric or suprasphincteric fistulas.
- Trial name
- NCT07102134
- Testing
- Suturing-LIFT procedure, Clipped-LIFT procedure
- Where
- China
- Volunteers
- 96 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Pancreatic Cancer, Bile Duct Cancer
Randomized Controlled Trial on Pancreatic Stent Tube in Pancreaticoduodenectomy
The purpose of this study is to determine which stent type is effective in the decrease of postoperative stay and complications across pancreaticojejunostomy after pancreaticoduodenectomy.
- Conditions
- Pancreatic Cancer, Bile Duct Cancer, Ampullary Cancer, Pancreatitis
- Trial name
- NCT00628186
- Testing
- external drainage tube [polyethylene pancreatic drainage tube], internal drainage tube [polyethylene pancreatic drainage tube]
- Where
- Japan
- Volunteers
- 100 people
- Sponsor
- Wakayama Medical University
Crohn's Disease, Complex Perianal Fistula
A Study of Darvadstrocel for Treating Complex Perianal Fistulas in Children and Teenagers With Crohn's Disease
A perianal fistula is an abnormal passageway that develops between the rectum and the skin near the anus. The fistula is considered complex if it branches into several openings or an abscess is also present.
- Trial name
- NCT04701411
- Testing
- Darvadstrocel
- Where
- 22 sites in Israel, Japan and 3 more
- Volunteers
- 7 people
- Sponsor
- Takeda
Crohn Disease, Perianal Fistula
Risankizumab for Refractory Perianal Fistulizing Crohn's Disease
Crohn's disease is an inflammatory bowel disease characterized by relapses and remissions, causing lesions throughout the digestive tract and accompanied by diarrhea, abdominal pain, and nutritional disorders.
- Conditions
- Crohn Disease, Perianal Fistula, Perianal Fistula Due to Crohn's Disease, Perianal Crohn's Disease
- Trial name
- RIS-PERIANAL (NCT07872449)
- Testing
- Risankizumab
- Where
- 4 sites in Japan
- Volunteers
- 25 people
- Sponsor
- Yuki Horio
Anal Fistula
INVESTIGATION OF THE EFFICACY OF FISTULA OBLITERATION BY STEAM ABLATION IN PERİANAL FISTULAS
Perianal fistula(PF) is one of the most frequent disease in anorectal disease.The incidence of PF is 8,6 -10 / 100 000 . The first surgical treatment is defined by Hippocrates in PF .This surgical treatment which found by…
- Trial name
- STEAM (NCT04811105)
- Testing
- steam ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Anal Fistula
Ligation of Inter-sphincteric Fistula Tract for Management of Anal Fistula
After abscess formation, an anal fistula is a common consequence, with crypto-glandular infection being the most commonly accepted causative cause.
- Trial name
- NCT05314205
- Testing
- ligation of inter-sphincteric fistula tract
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Al-Azhar University
Crohn Disease
Self Screening Tool for Crohn's Perianal Fistula
This study aims to develop a self-screening tool for Crohn's perianal fistula.
- Trial name
- NCT03288961
- Where
- South Korea
- Volunteers
- 146 people
- Sponsor
- Kyungpook National University Hospital
Inflammatory Bowel Disease, Perianal Fistula
Prevalence of Inflammatory Bowel Disease in Patients With Perianal Disease
To show that prevalence of inflammation of the small bowel in patients with anorectal disease is under-diagnosed based on colonoscopy ileoscopy alone.
- Conditions
- Inflammatory Bowel Disease, Perianal Fistula, Perianal Abscess
- Trial name
- NCT00972088
- Testing
- capsule endoscopy
- Where
- 3 sites in Israel
- Volunteers
- 26 people
- Sponsor
- Bikkur Holim Hospital
Anal Fistula
LIFT Technique Versus Seton in Management of Anal Fistula
Abscesses and anal fistulas represent about 70% of perianal suppuration, with an estimated incidence of 1/10,000 inhabitants per year and representing 5% of queries in coloproctology.
- Trial name
- NCT03311035
- Testing
- Seton, LIFT technique
- Volunteers
- 60 people
- Sponsor
- Assiut University
Post-COVID-19 Condition, Ulcerative Colitis
Emerging Indications for Hyperbaric Oxygen Treatment
This study will evaluate the effectiveness of hyperbaric oxygen therapy (HBOT) on treating emerging indications (i.e., conditions that have shown to potentially benefit from HBOT) using the Multicenter Registry for Hyperbaric…
- Conditions
- Post-COVID-19 Condition, Ulcerative Colitis, Crohn Disease, Calciphylaxis
- Trial name
- NCT07240649
- Testing
- Hyperbaric oxygen treatment (HBOT), 100% Oxygen
- Volunteers
- 100 people
- Sponsor
- Jay C. Buckey Jr.
Crohn Disease
Treatment and Fate in Fistulizing Crohn's Disease in a Pediatric Population
Crohn's disease is a inflammatory bowel disease evolving towards the destruction of the intestinal wall resulting in stenosing or perforating complications (fistulas, abscesses).
- Trial name
- NCT05759104
- Testing
- Infliximab, Stomy
- Volunteers
- 40 people
- Sponsor
- Central Hospital, Nancy, France
Fistula Vagina, Fistula;Rectal
Rectovaginal Fistula Repair
This study is a prospective evaluation of quality-of-life after rectovaginal fistula repair at our institution
- Trial name
- NCT05006586
- Where
- Sweden
- Volunteers
- 55 people
- Sponsor
- Uppsala University
Anal Fistula
Marsupialization of Anal Fistulotomy Wound Accelerates Healing and Decreases Post Operative Pain
comparison between to groups of patients with simple anal fistula one group underwent sistulotomy the other underwent fistulotomy and marsupialization of the wound edges , the investigator tested the incidence of postoperative…
- Trial name
- NCT04155905
- Testing
- fistulotomy and marsupialization of wound edges, fistulotomy
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Zagazig University
Anal Fistula
3D Endoanal Ultrasound and Anal Fistula
The study aims to evaluate the use of 3D endoanal ultrasound in preoperative management of anal fistula disease.
- Trial name
- UFU (NCT03937752)
- Testing
- 3D endodanal ultrasound
- Where
- Sweden
- Volunteers
- 95 people
- Sponsor
- Region Skane
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Anal Fistula
Treatment of Anal Fistulas Advancement Flap
This study comprises a prospective study of 40 patients with transphincteric anal fistula. The patients were classified into two groups: Group I: Fistulectomy, closure of internal sphincter and rectal advancement flap includes…
- Trial name
- flap (NCT01042821)
- Testing
- partial rectal wall advancement flap, mucosal advancement flap
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mansoura University