Clinical trials: Language Disorder
Preterm Birth, Language Development
Very Preterm Children With Language Delay and Parent Intervention
In studies of children born at term, language delay at the age of 2 years exhibits a spontaneously favourable course in 30 to 50% by the age of 3 years.
- Conditions
- Preterm Birth, Language Development, Speech Therapy
- Trial name
- EPILANG (NCT02042235)
- Testing
- Parent-implemented intervention
- Where
- 15 sites in France
- Volunteers
- 67 people
- Sponsor
- Lille Catholic University
Schizophrenia and Related Disorders
Linguistic Predictors of Outcomes in Psychosis
Longitudinal observational study of the relationship between speech patterns and clinical symptoms in schizophrenia spectrum disorders.
- Trial name
- LPOP (NCT05601050)
- Testing
- There is no intervention
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Northwell Health
Autism Spectrum Disorder, Autistic Disorder
Telehealth Parent-Implemented Intervention for Young Children With Autism Spectrum Disorder (ASD)
The primary objective of this research study is to improve outcomes involving core social-communication symptoms for young children with ASD or social communication delays by increasing access to clinically validated early…
- Conditions
- Autism Spectrum Disorder, Autistic Disorder, Active Autistic Disorder, Autism
- Trial name
- NCT05176808
- Testing
- Early Achievements- Parent Coaching Intervention
- Where
- United States
- Volunteers
- 117 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Language Development Disorders, Speech and Language Disorder
Efficiency of Speech and Language Intervention on Achievement of Children With Developmental Language Disorder
Children with Developmental Language Disorder (DLD) have many linguistic difficulties in syntax, lexicon, morphology and phonology.
- Conditions
- Language Development Disorders, Speech and Language Disorder, Therapy
- Trial name
- DYSPHADEV (NCT04926311)
- Where
- France
- Volunteers
- 130 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Hearing Impaired Children
Inter Disciplinary Approach to Vocabulary Development in Hearing Impairment
The research aims to address to address the role of interdisciplinary working between professionals in the field of speech and language pathology/therapy.
- Trial name
- NCT04962828
- Testing
- Vocabulary based intervention- Non Collaborative, Vocabulary based intervention - Collaborative
- Where
- Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
Amyotrophic Lateral Sclerosis, Brain Stem Stroke
Real World Testing of a Brain-Computer Interface
The goal of this project is to test a new AAC-BCI device comparing gel and dry electrode headgear used for communication while providing clinical care.
- Conditions
- Amyotrophic Lateral Sclerosis, Brain Stem Stroke, Cerebral Palsy, Traumatic Brain Injury
- Trial name
- NCT04026581
- Testing
- Speech generating device (SGD) evaluation including BCI access, Training and treatment
- Where
- 2 sites in United States
- Volunteers
- 19 people
- Sponsor
- University of Pittsburgh
Prostate Cancer
Testing the Helpfulness of 2 Decision Aids for Prostate Cancer
The purpose of this study is to test different methods for communicating information about prostate cancer treatment to men. The investigators are studying how best to present information so men can make informed decisions about…
- Trial name
- NCT00432601
- Testing
- type of decision aid
- Where
- 4 sites in United States
- Volunteers
- 1,028 people
- Sponsor
- VA Office of Research and Development
Hearing Loss, Language Development
Improving Outcomes Using Technology for Children Who Are DHH
This study evaluates the efficacy of using augmentative and alternative communication (AAC) technology for enhancing language development in children who are deaf or hard of hearing.
- Conditions
- Hearing Loss, Language Development, Social Behavior
- Trial name
- NCT02998164
- Testing
- augmentative and alternative communication technology, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 154 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism Spectrum Disorder, Social Communication Disorder
Virtual Group Social ABCs - Multi-site Randomized Controlled Trial
The goal of this randomized control trial is to test the efficacy of the Social ABCs 6 week, group-based model using a virtual delivery platform.
- Conditions
- Autism Spectrum Disorder, Social Communication Disorder, Autism or Autistic Traits, Autism Spectrum Disorder With Impaired Functional Language
- Trial name
- NCT05663970
- Testing
- VG Social ABCs
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Cerebral Palsy
Translation of the Cerebral Palsy Quality of Life Questionnaire in Local Languages of Pakistan.
Descriptive analytical study to translate the CP-QOL into local languages of Pakistan that are, Pashto, Urdu, Punjabi, Sindhi and Balochi languages.
- Trial name
- NCT04852159
- Where
- Pakistan
- Volunteers
- 525 people
- Sponsor
- Riphah International University
Stuttering
Development and Pilot Testing of Virtually Simulated Intervention for Patients Having Stuttering
This study aims to develop and pilot test a culturally appropriate virtual reality (VR)-based speech restructuring intervention for individuals with stuttering in Pakistan.
- Trial name
- NCT07833969
- Testing
- Virtually Simulated Intervention
- Where
- Pakistan
- Volunteers
- 10 people
- Sponsor
- Riphah International University
Language Impairment
Delivering EMT Via Telehealth to Children and Families
In the U.S., approximately 12% of children under 36 months have language impairments, yet less than 2% receive early language intervention.
- Trial name
- NCT04604821
- Testing
- Enhanced Milieu Teaching, Parent Education
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Spinal Cord Injury
Large Language Models for Epidural Stimulation Electrode Mapping in Spinal Cord Injury
This observational and methodological study aims to compare the performance of large language models in generating electrode contact configuration recommendations for epidural electrical stimulation in spinal cord injury.
- Trial name
- NCT07817238
- Testing
- ChatGPT-4o Large Language Model, Claude Large Language Model, Grok 3 Large Language Model
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Istanbul Gelisim University
Rolandic Epilepsy, Apraxia
Scholar Performance and Praxis Assessment in Children With Rolandic Epilepsy
Rolandic Epilepsy is the most common form of childhood epilepsy. It is classified as idiopathic, age-related epilepsy syndrome with benign evolution.
- Trial name
- NCT01046760
- Testing
- Language Assessment
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Genetic Syndrome, Language Development
Study of an Early Parenting Intervention for Children With Genetic Abnormalities and Mental Health Problems
The GAP study is a randomized controlled trial that aims to determine the feasibility and efficacy of the "Incredible Years Autism Spectrum and Language Delays" (IY-ASLD®) intervention for families of children with developmental…
- Conditions
- Genetic Syndrome, Language Development, Autism or Autistic Traits, Parenting
- Trial name
- The GAP (NCT06125093)
- Testing
- Incredible Years Autism Spectrum and Language Delays Parent Program (IY-ASLD®)
- Where
- 3 sites in Spain
- Volunteers
- 53 people
- Sponsor
- Fundació Sant Joan de Déu
Developmental Dyslexia
Using fMRI to Evaluate Instructional Programs for Children With Developmental Dyslexia
Dyslexia is a common reading disorder. Specialized instructional programs can improve reading ability in children with dyslexia.
- Trial name
- NCT00068835
- Testing
- Lindamood-Bell training for dyslexia
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Diagnosis
Mitigating Automation Bias in Physician-LLM Diagnostic Reasoning Using Behavioral Nudges
The goal of this randomized controlled trial is to evaluate whether behavioral nudges can reduce automation bias, the uncritical acceptance of automated output, in physicians using large language models (LLM) like ChatGPT-5.1 for…
- Trial name
- NCT07328815
- Testing
- Behavioral Nudge Intervention
- Where
- Pakistan
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
Attention Deficit Hyperactivity Disorder, Dyslexia
Treatment of ADHD With Atomoxetine in Children & Adolescents With ADHD & Comorbid Dyslexia
This study will evaluate the effect of atomoxetine in treating Attention-Deficit/Hyperactivity Disorder (ADHD) symptoms in children and adolescents with ADHD and comorbid reading disability (dyslexia)
- Trial name
- NCT00607919
- Testing
- Atomoxetine
- Where
- 16 sites in United States
- Volunteers
- 209 people
- Sponsor
- Eli Lilly and Company
Glioblastoma, IDH-wildtype, Glioblastoma
The RECMAP-study: Resection With or Without Intraoperative Mapping for Recurrent Glioblastoma
Resection of glioblastoma in or near functional brain tissue is challenging because of the proximity of important structures to the tumor site.
- Conditions
- Glioblastoma, IDH-wildtype, Glioblastoma, Glioblastoma Multiforme of Brain, Astrocytoma, Malignant
- Trial name
- RECMAP (NCT06273176)
- Testing
- Awake mapping under local anesthesia, Asleep mapping under general anesthesia, Resection under general anesthesia without mapping
- Where
- 8 sites in United States, Belgium and 3 more
- Volunteers
- 225 people
- Sponsor
- Erasmus Medical Center
Developmental Language Disorders, Developmental Articulation Disorder
Smart Computing Models, Sensors, and Early Diagnostic Speech and Language Deficiencies Indicators in Child Communication
This clinical trial aims to justify a protocol for designing and developing an automated decision-making system to support and enhance screening and early detection procedures for developmental speech/language difficulties in…
- Conditions
- Developmental Language Disorders, Developmental Articulation Disorder, Speech Disorder, Neurodevelopmental Disorder (Diagnosis)
- Trial name
- SmartSpeech (NCT06633874)
- Testing
- TD Playing the Serious Game APSOU, Non-TD Playing Serious Game
- Where
- Greece
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- University of Ioannina