Clinical trials: Local Anesthesia
Cut Flexor Hand, Walant
Compare the Outcomes of Zone II Flexor Tendon Repair of the Hand Under General Anesthesia Versus WALANT
Comparison between results of repair of cut flexor zone II under General anesthesia and Walant
- Conditions
- Cut Flexor Hand, Walant, General Anesthesia
- Trial name
- NCT04089124
- Testing
- surgery of zone II cut flexor repair
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Assiut University
Dental Caries in Children, Anesthesia, Local
Efficacy of Ethyl Chloride Topical Anesthesia Application on the Pain Perception During Intra-oral Injections in Children in Comparison to Benzocaine Gel.
The goal of this single-blinded randomized controlled trial is to compare pain perception during buccal infiltration using indirect EC spray and topical anesthesia and BC 20% topical gel, among seven to 10-year-old school…
- Conditions
- Dental Caries in Children, Anesthesia, Local, Injection Site Discomfort
- Trial name
- NCT06011005
- Testing
- Ethyl Chloride spray (group A), Benzocaine gel 20% (group B)
- Where
- United Arab Emirates
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Anesthesia; Functional
Success Rate of Anterior Middle Superior Alveolar (AMSA) Nerve Block in Three Different Sites of Injection
AMSA nerve block injection is targeted anterior superior alveolar nerve and middle superior alveolar nerve branches of infraorbital nerve through nutrient canals.
- Trial name
- NCT02012257
- Testing
- AMSA nerve block injectio
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Pediatric Postoperative Pain
Postoperative Pain After Pediatric Umbilical Hernia Repair
The purpose of this study is to compare the use of ultrasound-guided bilateral rectus sheath blocks to local infiltration of anesthetic agent in the surgical wound in a pediatric population of patients undergoing umbilical hernia…
- Trial name
- NCT01015053
- Testing
- bilateral ultrasound-guided rectus sheath block, Wound infiltration
- Where
- 2 sites in United States
- Volunteers
- 53 people
- Sponsor
- Boston Children's Hospital
Local Anesthetic Complication
Comparative Effect of Palatal Injection in Pediatric Patient
The aim of this study is to compare the pain perception of pediatric patients during extraction with and without palatal injection and to show whether articaine HCl and lidocaine HCl can provide palatal anesthesia in maxillary…
- Trial name
- NCT06025825
- Testing
- Articaine Hydrochloride + Epinephrine, Lidocaine Hydrochloride + Epinephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara Yildirim Beyazıt University
Anesthesia
Comparison of the Effectiveness of Articaine Local Infusion and Lidocaine Nerve Block in Lower Posterior Tooth Extraction.
In this study 60 adult patients will participate and divided into two groups (30 for each). The first group will be anesthetized using 2 % lidocaine with 1:80,000 adrenaline by inferior alveolar nerve block technique, while the…
- Trial name
- NCT07048834
- Testing
- lidocaine local anesthetic drug, articaine local anesthetic drug
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Amjed Fouad Hussein
Local Anaesthetic, Dental Anxiety
Effect of a Vibration System on Pain Reduction During Injection of Local Dental Anaesthesia in Children
The study assesses the effect of a new vibration system on pain reduction during the injection of local anesthesia. Children undergoing dental treatment are allocated to two groups; one receiving the Buzz, a vibration system and…
- Trial name
- NCT03953001
- Testing
- Adminstration Technique using Buzzy external distractor, 2% Lidocaine with 1:50,000 epinephrine, Topical Anesthetic
- Where
- Saudi Arabia
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Imam Abdulrahman Bin Faisal University
Breast Cancer Female
USG PECS vs LIA for Breast Cancer Surgery
Breast cancer is the most common cancer for which women in the UK (United Kingdom) undergo surgery. A novel ultrasound guided regional anaesthetic technique called the 'Pecs 2' block has recently been described.
- Trial name
- NCT03555227
- Testing
- USG PECS2 with Drug A (active), Wound infiltration with Drug A (active)
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- National Health Service, United Kingdom
Behavior, Child, Anxiety, Dental
Virtual Reality in Pediatric Dentistry
Dental Fear and Anxiety is an emotional experiences affecting many children and adolescents which can lead to behavioral problems in the dental setting.
- Trial name
- NCT05585905
- Testing
- Virtual Reality, Basic Behavior Guidance Techniques
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Pain, Postoperative Pain
Comparison of Post-Operative Analgesia After Percutaneous Nephrolithotomy.
The rationale of this study was to compare the efficacy of peri-tract bupivacaine infiltration with intravenous post-operative analgesia following PCNL in reference to the context with the previous studies so that we can adopt…
- Trial name
- NCT04835116
- Testing
- Bupivacaine Hydrochloride 0.25% Injection. Paracetamol 650mg. Orphenadrine 50mg., paracetamol 1000mg. Tramadol 50mg. Dimenhydrinate 50mg.
- Where
- Pakistan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Armed Forces Institute of Urology, Rawalpindi
Oral Health Related Quality of Life OHRQoL
Does Treating Early Childhood Caries Under Local or General Anesthesia Have Varying Effects on OHRQoL
A two-arm randomized control trial is to compare the changes in OHRQoL scores among children treated for ECC under general (DGA) and local anesthesia (LA).
- Trial name
- NCT05761691
- Testing
- Dental treatment
- Where
- Saudi Arabia
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Riyadh Elm University
Regional Anesthesia, Postoperative Pain, Acute
Caudal Block and Transversus Abdominis Plane Block in Pediatric Inguinal Hernia Repair
Pediatric inguinal hernia repair (IHR) candidates experiences ordinarily mild to moderate pain, rarely severe pain in the postoperative period.
- Trial name
- NCT05286190
- Testing
- Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Peripheral Nerve Block, Post Operative Analgesia
Transversus Abdominis Plane Lock Versus Quadratus Lumborum Block in Children
Although abdominal wall surgeries are also as routinely performed on pediatric patients, postoperative pain in children has remained under-researched compared to adults.
- Conditions
- Peripheral Nerve Block, Post Operative Analgesia, Ultrasound-guided Regional Anesthesia
- Trial name
- NCT06861556
- Testing
- Ultrasound guided Transversus Abdominis Plane block with 0.2ml/kg bupivacaine 0.25%, Ultrasound-guided Quadratus Lumborum block with 0.2ml/kg bupivacaine 0.25%
- Where
- Tunisia
- Volunteers
- 90 people
- Sponsor
- Tunis University
Hip Surgery, Hip Arthroplasty
The Quadro-Iliac Plane (QIP) Block in Hip Surgery
The goal of this observational study is to learn about the effectiveness of different locoregional anesthesia techniques, particularly the Quadro-Iliac Plane (QIP) block, in patients undergoing hip surgery, including…
- Trial name
- QIP in hip (NCT07591311)
- Testing
- Fascia iliaca block (FIB)
- Where
- 2 sites in Italy
- Volunteers
- 80 people
- Sponsor
- San Giovanni di Dio Hospital
Anesthesia, Local Anesthesia
Can Caudal Dexmedetomidine Provide Effective Analgesia?
The goal of this clinical trial is to evaluate if caudal dexmedetomidine can provide effective analgesia during inguinoscrotal surgeries in pediatrics, if used caudally alone (and not as an adjunct to caudal bupivacaine).
- Trial name
- NCT05902780
- Testing
- Caudal Bupivacaine injection, Caudal Dexmedetomidine Injection
- Volunteers
- 50 people
- Sponsor
- Benha University
Anesthesia, Local, Ophthalmopathy
Comparison Between Peribulbar And Sub-tenon Blocks on Oculocardiac Reflex (OCR) During Pediatric Strabismus Surgery
The aim of this study is to compare between peribulbar block and subtenon block as an adjunct to general anesthesia in children undergoing strabismus surgery on oculocardiac reflex (OCR), post-operative analgesia and…
- Conditions
- Anesthesia, Local, Ophthalmopathy, Strabismus, Pediatric ALL
- Trial name
- NCT06293586
- Testing
- peribulbar block, sub-tenon block, Paracetamol
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cairo University
Children's Anxiety Levels, Children's Behavior
The Effect of Vibration Devices on Pain and Discomfort During Local Anesthesia Administration in Children
This split-mouth randomized clinical trial will be conducted at the Department of Pediatric Dentistry, King Abdulaziz University Dental Hospital (KAAUDH).
- Conditions
- Children's Anxiety Levels, Children's Behavior, Physiological Changes (Heart Rate), Obejective Pain and Discomfort
- Trial name
- NCT07384923
- Testing
- DentalVibe intraoral vibration device, Buzzy Bee® extraoral vibration device
- Where
- Saudi Arabia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- King Abdulaziz University
Pain
Continuous Infusion of Local Anesthetic for Post-operative Pain Control in Ukraine
Ukraine is a newly sovereign country in Eastern Europe with a large burn population. With the collapse of the Soviet Union, burn programs have become decentralized and resources for maintaining facilities have dwindled.
- Trial name
- NCT01863940
- Testing
- Wound Catheter
- Where
- Ukraine
- Volunteers
- 67 people
- Sponsor
- Massachusetts General Hospital
Rupture of Anterior Cruciate Ligament, Tear of Anterior Cruciate Ligament
Trial Evaluating Postop Pain and Muscle Strength Among Regional Anesthesia Techniques for Ambulatory ACL Reconstruction
Despite the apparent multifaceted benefit in differentiating blockade sites and duration of nerve blockade, the efficacy of continuous adductor canal blockade utilized specifically in ACL reconstruction has not been extensively…
- Trial name
- NCT02584452
- Testing
- Mepivacaine, adductor canal continuous nerve catheter, Normal Saline as bolus followed by bupivacaine
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Vanderbilt University Medical Center
Anesthesia, Local
Comparing the Hemodynamic Effects of Epinephrine Versus Dexmedetomidine as an Adjuvant to Bupivacaine in Caudal Anaesthesia Assessed by Cardiometry
Electrical cardiometry (EC) is a non-invasive method of estimating cardiac parameters by measuring changes in thoracic bioimpedance during the cardiac cycle.
- Trial name
- NCT05860010
- Testing
- Epinephrine injection, Dexmedetomidine, Bupivacaine
- Where
- 2 sites in Egypt
- Volunteers
- 39 people
- Sponsor
- Kasr El Aini Hospital