Clinical trials: Lung Function
Athletic Performance, Muscle Oxygenation
Effects of Core and Inspiratory Muscle Training on Muscle Oxygenation and Athletic Performance İn Young Soccer Players
The purpose of this randomized controlled trial is to investigate the effects of core training and inspiratory muscle training (IMT) on muscle oxygenation and athletic performance in youth male soccer players aged 15-18.
- Conditions
- Athletic Performance, Muscle Oxygenation, Respiratory Function
- Trial name
- NCT07657065
- Testing
- Core Training Program, Inspiratory Muscle Training (IMT)
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Istinye University
Cystic Fibrosis
Cystic Fibrosis and Endothelial Function: At Rest and During Exercise
Perhaps one of the most disturbing aspects of Cystic Fibrosis (CF) is the associated premature death. Oxidative stress has been observed in patients with CF and exercise intolerance has been shown to predict mortality in patients…
- Trial name
- NCT01772758
- Testing
- BH4 5mg, BH4 20mg, Antioxidant Cocktail
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Augusta University
Wheezing, LRTI
Protecting Preterm Infants From Respiratory Tract Infections and Wheeze by Using Bacterial Lysates.
The primary objective of this study is to reduce respiratory tract infections and wheezing in moderate-late preterms in the first years of life by bacterial lysate administration.
- Conditions
- Wheezing, LRTI, Premature
- Trial name
- PROTEA (NCT05063149)
- Testing
- Broncho-Vaxom
- Where
- Netherlands
- Volunteers
- 500 people
- Sponsor
- Franciscus Gasthuis
Pulmonary Hypertension
Study of Remodulin® in Pediatric Pulmonary Hypertension With Single Ventricular Physiology After Fontan Surgery
The aim of this study is to determine the safety and efficiency of Remodulin®（Treprostinil Injection）to reduce the pulmonary arterial pressure and prevent pulmonary hypertension (PH) after Fontan operation with univentricular…
- Trial name
- NCT02865733
- Testing
- Remodulin, distilled water
- Volunteers
- 36 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Inspiratory Muscle Training
The Effect of Inspiratory Muscle Training on Respiratory Function, Balance and Functional Capacity in Trainable Mentally Handicapped Children
Background: The aim of this study was to examine the effect of inspiratory muscle training on respiratory functions, balance and functional capacity in trainable mentally disabled individuals.
- Trial name
- Inspiratory (NCT06635343)
- Testing
- CPRP, Experimental Inspiratuar Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Kayseri University
Bronchial Asthma
Coupled Inspiratory and Expiratory Muscle Training in Children With Bronchial Asthma
This study was designed to assess the effect of inspiratory and expiratory muscle training in the same cycle on respiratory muscle strength, pulmonary functions, perception of asthma symptoms in children with bronchial asthma.
- Trial name
- NCT05212558
- Testing
- Inspiratory muscle training, Combined inspiratory and expiratory muscle training
- Where
- Saudi Arabia
- Volunteers
- 51 people
- Sponsor
- Cairo University
Lung Diseases, Obstructive, Pulmonary Rehabilitation
Respiratory Function in Patients With Post-tuberculosis Lung Impairment
Pulmonary tuberculosis (TB) is an important risk factor for chronic respiratory disease due to residual lung damage. A recent review of the literature on TB sequelae and rehabilitation has provided clear evidence that TB is…
- Conditions
- Lung Diseases, Obstructive, Pulmonary Rehabilitation, Lung TB
- Trial name
- NCT03821285
- Testing
- Pulmonary Rehabilitation
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi dell'Insubria
COVID-19, MIS-C Associated With COVID-19
Exercise Fatigue Parameters and Endothelial Function in Pediatric Patients With a History of COVID-19 Infection or MIS-C
Acute coronavirus disease 2019 (COVID-19) infection can include cardiac and pulmonary manifestations as well as post-infectious complications such as multisystem inflammatory syndrome (MIS-C), also known as pediatric inflammatory…
- Trial name
- NCT05205642
- Testing
- Cardiopulmonary exercise test (CPET), Peripheral Arterial Tonography (PAT) using the EndoPAT™ device, Endothelin
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Rambam Health Care Campus
Healthy, Cystic Fibrosis (CF)
MRI for Non-Invasive Imaging in Neonates and Children
The purpose of this study is to develop rapid MRI techniques for imaging the lung with hyperpolarized helium-3 gas as an inhaled contrast agent.
- Conditions
- Healthy, Cystic Fibrosis (CF), Asthma, Bronchopulmonary Dysplasia (BPD)
- Trial name
- NCT02163681
- Testing
- Hyperpolarized Helium-3 MRI of the chest
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Cerebral Palsy, Respiratory Function Tests
Respiratory Function, Respiratory Muscle Strength, and Hand Function in Hemiparetic Cerebral Palsy
The goal of this observational study is to learn how respiratory function and respiratory muscle strength are related to hand use in children and teenagers with hemiparetic cerebral palsy (CP) aged 6 to 18 years.
- Conditions
- Cerebral Palsy, Respiratory Function Tests, Fine Motor Skills
- Trial name
- NCT07394439
- Volunteers
- 37 people
- Sponsor
- Halic University
Right Ventricular Dysfunction
Evaluation of Right Ventricular Function Post Mitral Valve Operations
We aim to determine the function of Right ventricle post mitral valve surgeries in patients with pulmonary hypertension using transthoracic echocardiography3- and 6-months post-operatively to detect the effect of mitral valve…
- Trial name
- NCT05620992
- Testing
- Echocardiography
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
Chronic Lung Disease, Quality of Life
Pulmonary Rehabilitation and Quality of Life in Children With Chronic Lung Diseases: A Multidisciplinary Approach
Chronic lung diseases (CLDs) such as asthma, cystic fibrosis, and bronchopulmonary dysplasia significantly impact pediatric patients' respiratory function and overall well-being.
- Conditions
- Chronic Lung Disease, Quality of Life, Respiratory Function Impaired
- Trial name
- NCT06870032
- Testing
- standard medical care, structured pulmonary rehabilitation
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Horus University
Cystic Fibrosis in Children
Combined Effect of CFTR Protein Modulator Drugs and Exercise in Cystic Fibrosis
This study aims to assess the effects of programmed exercise combined with CFTR protein modulator drugs in the cardiorespiratory fitness, strength, functional capacity and agility in a group of young patients with Cystic Fibrosis.
- Trial name
- NCT04415268
- Testing
- Exercise, Unsupervised exercise, CFTR Modulators
- Where
- Spain
- Sponsor
- Universidad Europea de Madrid
Asthma
Lung Function Changes of Induced Asthma Children Treated With Inhaled MgSO4
As a non-selective bronchodilator, magnesium sulfate (MgSO4) is effective when administered intravenously in the treatment of the patients with acute severe asthma not responding to conventional therapy (oxygen, nebulized…
- Trial name
- NCT01856959
- Testing
- Magnesium Sulfate, magnesium sulfate & albuterol, Albuterol
- Where
- China
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Chongqing Medical University
Asthma
Clinical Trial of Fluticasone Versus Placebo at the Onset of a Cold for Children With Asthma
The purpose of this study is to determine, in children aged 1 to 6 years with recurrent asthma induced by upper respiratory tract infections (URTI), whether the administration of high doses of inhaled fluticasone started at the…
- Trial name
- NCT00238927
- Testing
- inhaled fluticasone 750 mcg/day twice daily until 2 days without symptoms (maximum 15 consecutive days)
- Where
- 5 sites in Canada
- Volunteers
- 150 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cystic Fibrosis
Dissection of Staphylococcus Aureus Infection From Colonization in Cystic Fibrosis Patients
Staphylococcus aureus is not only one of the first pathogens infecting the airways of cystic fibrosis (CF) patients, but also a highly prevalent microorganism (>60% of all CF patients; European and American CF registries; (4,25)…
- Trial name
- StaphCI (NCT00669760)
- Testing
- non-interventional study
- Where
- 17 sites in Austria, Germany
- Volunteers
- 195 people, healthy volunteers welcome
- Sponsor
- University Hospital Muenster
Obesity
Effects of Blowing Balloon Therapy FUNCTION, DYSPNEA AND QUALITY OF LIFE IN OBESE CHILDREN
The respiratory system is divided into upper and lower tracts and functions through gaseous exchange, ventilation, and perfusion, with normal breathing depending on lung compliance, airway resistance, and muscular strength.
- Trial name
- NCT07576478
- Testing
- Blowing Balloon Therapy Group
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Pregnancy, Smoking
Evaluating the Effects of Supplemental Vitamin C on Infant Lung Function in Pregnant Smoking Women
Women who smoke during their pregnancy place their unborn child at an increased risk of health problems, including decreased lung function and possible lung diseases later in life.
- Trial name
- NCT00632476
- Testing
- Vitamin C
- Where
- United States
- Volunteers
- 282 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Asthma
Effect of Air Pollution on Long-Term Asthma Severity and Lung Function in Children
Asthma can be caused by many factors, including mold, pollen, and other airborne pollutants. The purpose of this study is to evaluate the effect that air pollution has on the long-term severity of asthma symptoms and lung…
- Trial name
- FACES (NCT00336050)
- Volunteers
- 315 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Asthma
Study In Airway Physiology In Children SERETIDE DISKUS ® Inhlaer and FLIXOTIDE® Inhaler Are Trademarks of GSK Group of Companies.
Comparison of two asthma treatments by lung function measures.
- Trial name
- NCT00169546
- Testing
- Salmeterol/fluticasone propionate, Fluticasone propionate
- Where
- 2 sites in New Zealand, United Kingdom
- Volunteers
- 64 people
- Sponsor
- GlaxoSmithKline