Clinical trials: Moderately Obese
Obesity, Obstructive Sleep Apnea (Moderate to Severe)
Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in Adolescents
The research study is being done to test heated humidified high-flow air (HHF), as a treatment for OSA.
- Conditions
- Obesity, Obstructive Sleep Apnea (Moderate to Severe), Central Sleep Apnea
- Trial name
- NCT05354401
- Testing
- HHF
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- The Hospital for Sick Children
Bardet Biedl Syndrome (BBS), Alström Syndrome (AS)
Setmelanotide (RM-493), Melanocortin-4 Receptor (MC4R) Agonist, in Bardet-Biedl Syndrome (BBS) and Alström Syndrome (AS) Participants With Moderate to Severe Obesity
This pivotal, phase 3 study is designed to confirm the efficacy and safety of setmelanotide, a potent melanocortin receptor type 4 (MC4R) agonist, for the treatment of obesity and hyperphagia in participants with Bardet Biedl…
- Trial name
- NCT03746522
- Testing
- Setmelanotide
- Where
- 12 sites in United States, Canada and 4 more
- Volunteers
- 52 people
- Sponsor
- Rhythm Pharmaceuticals, Inc.
Obese Children and Adolescents, Adolescent Obesity
Response of Lipid Profile to Virtual Reality Games Versus Moderate Aerobic Exercise Training in Children With Obesity
This trial is aiming to study the effect of virtual reality video gaming in comparison with moderate intensity aerobic exercises on lipid profile in children with Obesity
- Conditions
- Obese Children and Adolescents, Adolescent Obesity, Obesity, Body Mass Index
- Trial name
- NCT07073651
- Testing
- Moderate Intensity Aerobic Exercise, Dietary Advices, Virtual reality games exercise
- Where
- 2 sites in Egypt
- Volunteers
- 120 people
- Sponsor
- Badr University
Physical Inactivity, Health Behavior
OLYMPIC-S: Outcomes of a Life-stYle Multicomponent Physical-activity Intervention in Children at School
OLYMPIC-S is a cluster randomized controlled trial evaluating a four-month school-based intervention designed to increase moderate-to-vigorous physical activity and promote healthy habits among children in the fourth, fifth and…
- Conditions
- Physical Inactivity, Health Behavior, Child Health
- Trial name
- OLYMPIC-S (NCT07737548)
- Testing
- Olympic School
- Where
- Spain
- Volunteers
- 893 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Healthy, no Evidence of Disease, Obesity
Study of a Smart Growth Community's Effect on Prevention of Obesity in Middle-, Moderately Low- and Low-Income Families
RATIONALE: Overweight and obesity have been associated with multiple types of disease, including cancer. Living in a smart growth community may encourage behaviors that would reduce the risk of obesity.
- Conditions
- Healthy, no Evidence of Disease, Obesity, Weight Changes
- Trial name
- NCT00986011
- Testing
- questionnaire administration, study of socioeconomic and demographic variables, survey administration
- Where
- United States
- Volunteers
- 780 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Physical Activity, Social Identity
"We Are an Active Family": Promoting Child Physical Activity Through Social Identity Formation in the Family System
The purpose of our study is to explore the effectiveness of physical activity (PA) identity formation in the family system as a promotor of long-term PA.
- Trial name
- NCT05794789
- Testing
- Social Identity
- Where
- 2 sites in Canada
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- University of Victoria
Metabolism, Physical Fitness
High Intensity Interval Versus Continuous Moderate Intensity Training: Maximizing the Benefits of Exercise in Overweight Adolescents
6-week, single site, two parallel arm, randomized, controlled trial comparing the effectiveness of a High Intensity Interval Training (HIIT) versus a continuous Moderate Intensity Training (MIT) program on cardiovascular and…
- Trial name
- HIIT-MAX (NCT01935323)
- Testing
- High Intensity Interval Training, Moderate Intensity Training
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Feeding Behavior
Effect of Varying Proportions of Low and High Energy Dense Foods Over 5 Days in Preschool Children
In this study, the investigators will vary the proportions of high- and low-energy-dense foods served to preschool children at all meals and snacks during three 5-day periods.
- Trial name
- NCT03242863
- Testing
- Food proportionality
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Penn State University
Non-Alcoholic Fatty Liver Disease, Obesity
Moderately Carbohydrate-restricted Diet to Treat NAFLD in Adolescents
This will be a 6-month randomized clinical trial with two arms: moderately carbohydrate-restricted diet and a fat-restricted control diet.
- Trial name
- NCT05268042
- Testing
- Moderately carbohydrate-restricted diet, Fat-restricted diet
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Alabama at Birmingham
Physical Inactivity in Children
Active Video Games on Physical Activity (Main Trial)
The purpose of the study is to test the effects of different versions of active video games (AVGs) on body composition, cardiometabolic risks, and cognitive functions among overweight/obese children over 6 months.
- Trial name
- NCT04116515
- Testing
- Xbox / active video games, Animated cartoon narratives, Standard clinical care
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Northeastern University
Weight Loss, Obese Children and Adolescents
The Therapeutic Effect of Different Exercise Intensities on Weight Loss in Obese Children
The incidence of childhood obesity is increasing, followed by metabolic diseases related to overweight and obesity in children. High intensity interval training (HIIT) has recently been shown to improve the body composition and…
- Trial name
- NCT06205563
- Testing
- high-intensity interval training, moderate intensity continuous training
- Volunteers
- 388 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
To Compare the Difference of AHI Variation Between LSG and Combined Surgery
Effects of Combined Surgery on Obstructive Sleep Apnea in Obese Patients: an Open-label Randomized Controlled Clinical Trial
This research is created for compare the difference of AHI variation between LSG and combined surgery on obstructive sleep apnea in obese patients , evaluate the risk of combined surgery and explore the correlative factor of the…
- Trial name
- NCT03227939
- Testing
- Laparoscopic sleeve gastrectomy（LSG）, Uvulopalatopharyngoplasty(UPPP) and Adenoidectomy/Tonsillectomy
- Volunteers
- 100 people
- Sponsor
- Bing Wang
Morbid Obesity
Efficacy and Mechanism Study of Bariatric Surgery to Treat Moderate to Severe Obesity in Han Chinese Population
This is a long-term follow-up and interventional study in individuals who have been diagnosed with moderate to severe obesity with or without diabetes.
- Trial name
- NCT02653430
- Testing
- Sleeve gastrectomy
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Obesity
Effect of Exercises on Physical Health and Cardiorespiratory Fitness in Obese Women
The study will be a Randomized clinical trial and will be conducted in services hospital lahore. The sample size of 50 patients will be taken in this study to find the effects of high intensity interval training versus moderate…
- Trial name
- NCT05618899
- Testing
- HIGH INTENSITY INTERVAL TRAINING, MODERATE INTENSITY EXERCISE
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Riphah International University
Overweight, Obesity
Mono Unsaturated Fatty Acids in Obesity - Weight Maintenance and Prevention of Lifestyle Diseases in Obese Subjects.
The purpose of this study is to investigate the effect of three diets different in type and amount of fat in weight maintenance and prevention of life-style diseases in obese subjects.
- Trial name
- NCT00274729
- Testing
- Mono Unsaturated Fatty Acids in Obesity
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Binge Eating Disorder
An Open-Label Trial of Memantine in the Treatment of Binge Eating Disorder
We hypothesize that memantine may be a safe and effective treatment for moderate to severe binge eating disorder associated with obesity.
- Trial name
- NCT00330655
- Testing
- memantine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Mclean Hospital
High Intensity Interval Training, Child Obesity
The Effect of HIIT in Handling Obesity in Children
In this study the investigators wish to investigate whether a short duration High-intensity Interval Training(HIT) is superior to a moderate activity training modus with regards to improving weight-loss, Blood pressure and sleep…
- Trial name
- NCT03433690
- Testing
- HIIT, Moderate training
- Volunteers
- 30 people
- Sponsor
- Regionshospital Nordjylland
Obesity
Nutrigenomics And Children Obesity: A Moderate Weight Loss Intervention Study
The consumption of diets enriched in proteins (legumes and fish) or antioxidant (fruits and vegetables) could have beneficial effects beyond those of the caloric restriction on biomarkers of the inflammatory and oxidative status.
- Trial name
- NUGENOI (NCT01329367)
- Testing
- Control group, Protein group, Antioxidant group
- Where
- 2 sites in Spain
- Volunteers
- 42 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra