Clinical trials: Muscle
Cerebral Palsy, Spastic
Whole-body Vibration in Spastic Hemiplegic Cerebral Palsy
To target spasticity, balance and mobility whole body vibration exercises along with selected physical therapy is given to experimental group.
- Trial name
- NCT04087330
- Testing
- Group 1 Experimental group, Group 2 Control group
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Myopathy, Neuropathy
Identification of Tongue Involvement in Late-Onset Pompe Disease
This purpose of this study is to determine if tongue strength and tongue ultrasound measurements differentiates patients with untreated late-onset Pompe Disease (LOPD) from patients with acquires/hereditary myopathies or…
- Conditions
- Myopathy, Neuropathy, Glycogen Storage Disease Type II (Late-onset Pompe Disease)
- Trial name
- NCT02765828
- Testing
- Observational study
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Duke University
Occupational Health, Sick Leave
Effects of Regulatory Tools on Work Environment and Employee Health
This study evaluates the effects of the Labour Inspection Authority's regulatory tools on workplace exposures to prevent employee ill health.
- Conditions
- Occupational Health, Sick Leave, Occupational Exposure
- Trial name
- NCT03855163
- Testing
- Inspection visits, Guidance workshops, Online risk assessment tool
- Where
- 130 sites in Norway
- Volunteers
- 2,555 people, healthy volunteers welcome
- Sponsor
- National Institute of Occupational Health, Norway
Duchenne Muscular Dystrophy
Determine the Safety and Dose of EN001 in Patients With Duchenne Muscular Dystrophy(DMD)
Open-label, Dose-escalation, Phase 1 Clinical Trial to Determine the Safety and Dose of EN001 in Patients with Duchenne Muscular Dystrophy(DMD)
- Trial name
- NCT05338099
- Testing
- EN001
- Where
- South Korea
- Volunteers
- 7 people
- Sponsor
- ENCell
Amyotrophic Lateral Sclerosis
Inspiratory Muscle Training With Powerbreath Device in Patients With ALS
Abstract: Context/background: people affected by Amyotrophic Lateral Sclerosis (ALS) see their own life totally disturbed after the diagnosis.
- Trial name
- NCT04889248
- Testing
- Inspiratory Muscle Training with Powerbreath IMT device.
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidad Francisco de Vitoria
Duchenne Muscular Dystrophy (DMD), Lower Urinary Tract Symptoms (LUTS)
Urotherapy Education for Families of Children With Duchenne Muscular Dystrophy
This study aims to investigate the effects of urotherapy education provided to families of children with Duchenne muscular dystrophy on parents' knowledge, lifestyle changes, and satisfaction with the education.
- Trial name
- NCT07821125
- Testing
- Urotherapy Education
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Lokman Hekim University
Adolescent Idiopathic Scoliosis
The Effects of Core Stabilization Exercises on Balance, Proprioception, and Knee Muscle Strength in Children with Adolescent Idiopathic Scoliosis
Scoliosis can be defined as a 3-dimensional deformity in which the lateral deviation and rotation of the vertebrae occur, as well as changes in the physiological curves of the spine.
- Trial name
- NCT05557773
- Testing
- Home Based Traditional Scoliosis Exercises, Core Stability Training
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul University
Balance, Duchenne Muscular Dystrophy
The Effect of Kinesiology Taping on Balance in Duchenne Muscular Dystrophy
Investigators investigated that the effects of kinesilogy taping on balance in patients with Duchenne Muscular Dystrophy
- Trial name
- NCT03541070
- Testing
- Kinesiology tape
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Hacettepe University
Rhabdomyosarcoma
Treatment of Newly Diagnosed Rhabdomyosarcoma Using Molecular Risk Stratification and Liposomal Irinotecan Based Therapy in Children With Intermediate and High Risk Disease
This is a phase II study to determine safety and efficacy of combining liposomal irinotecan with vincristine alternating with VAC in intermediate-risk patients, liposomal irinotecan with temozolomide and vincristine alternating…
- Trial name
- NCT06023641
- Testing
- Vincristine, Dactinomycin, Cyclophosphamide
- Where
- 3 sites in United States
- Volunteers
- 135 people
- Sponsor
- St. Jude Children's Research Hospital
Thalassemia
Effect of Exercise on Body Composition and Bone Health in Patients With Thalassemia
The goal of this clinical trial is to determine if a weight bearing exercise intervention can improve body composition and bone health in adolescents and adults with Thalassemia.
- Trial name
- NCT07064941
- Testing
- Exercise
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Francisco
Myotonic Dystrophy 1, Huntington Disease
NIPD on cffDNA for Triplet Repeat Diseases
The purprose of this study is to develop and validate an analytical NIPD test for triplet repeat disesases by NGS analysis from maternal blood, searching for the familial mutation in families at risk of having one of the…
- Conditions
- Myotonic Dystrophy 1, Huntington Disease, Fragile X Syndrome
- Trial name
- NCT04698551
- Testing
- Non invasive prenatal diagnosis
- Where
- France
- Volunteers
- 36 people
- Sponsor
- University Hospital, Montpellier
Diplegic Cerebral Palsy
"Immediate Effect of DAFO on Gross Motor Function and Balance in Diplegic Cerebral Palsy
" Study will investigate the immediate effect of DAFO usage on balance and gross motor functions in individuals with spastic diplegic cerebral palsy.
- Trial name
- NCT06343688
- Testing
- "Assessment of Balance and Lower Extremity Gross Motor Function with and without DAFO"
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Abant Izzet Baysal University
Neuroblastoma, Medulloblastoma
Accurate Diagnosis and Grading of Pediatric Solid Tumors Based on Pathological Large Models
Pediatric malignancies are the second leading cause of death in the pediatric population, with solid tumors accounting for approximately 60% of all pediatric malignancies.
- Conditions
- Neuroblastoma, Medulloblastoma, Wilms Tumor, Hepatoblastoma
- Trial name
- NCT06822842
- Where
- China
- Volunteers
- 1,229 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Mental Health Issue, Musculoskeletal Pain
CLIMB: Climbers' Longitudinal Attitudes to Injuries, Mental Health and Body Image
Eating disorders (ED) are serious mental illnesses with high mortality rates and significant impact on an individual's quality of life.
- Conditions
- Mental Health Issue, Musculoskeletal Pain, Eating Disorders, Relative Energy Deficiency in Sport
- Trial name
- NCT05587270
- Testing
- Web based surveys, DXA
- Where
- Sweden
- Volunteers
- 366 people, healthy volunteers welcome
- Sponsor
- Göteborg University
Temporomandibular Disorder
Standard Care With LLLT & Myofascial Release Versus Standard Care Alone in Pregnant Women With Temporomandibular Disorder
This study will investigate a novel approach to treat pregnant women with tempromandibular disorder using a combined method of low level laser therapy, myofascial release and standard care versus standard care alone.
- Trial name
- NCT05138354
- Testing
- Low Level laser therapy, Myofascial release, Standard care
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- October 6 University
Duchenne Muscular Dystrophy
An Extension Study to Assess Vamorolone in Boys With Duchenne Muscular Dystrophy (DMD)
The main purposes of this study are to see if it is safe to use a new medication called vamorolone for more than two weeks in children with Duchenne muscular dystrophy (DMD), to see if vamorolone works for the treatment for DMD…
- Trial name
- NCT02760277
- Testing
- Vamorolone 0.25 mg/day/day, Vamorolone 0.75 mg/day/day, Vamorolone 2.0 mg/day/day
- Where
- 12 sites in United States, Australia and 4 more
- Volunteers
- 48 people
- Sponsor
- ReveraGen BioPharma, Inc.
Thymidine Kinase 2 Deficiency
An Open-Label Study of Continuation Treatment With Combination Pyrimidine Nucleosides in Patients With TK2 Deficiency
This is a Phase 2 prospective open-label treatment study of the safety and efficacy of doxecitine and doxribtimine in study participants with thymidine kinase 2 (TK2) deficiency who participated in the retrospective study…
- Trial name
- Continuation (NCT03845712)
- Testing
- doxecitine and doxribtimine
- Where
- 8 sites in United States, Israel and 1 more
- Volunteers
- 47 people
- Sponsor
- UCB BIOSCIENCES, Inc.
Intermittent Exotropia
Lateral Rectus Muscle and Anterior Segment Optical Coherence Tomography (AS-OCT)
•Background and study aims : The investigators conducted this study to evaluate the movement of extraocular muscle after strabismus surgery with non-invasive tool called AS-OCT.
- Trial name
- NCT02383381
- Testing
- lateral rectus recession
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Sarcoma
Combination Chemotherapy and Peripheral Stem Cell Transplantation in Treating Patients With Sarcoma
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug and combining chemotherapy with peripheral stem cell transplantation may allow…
- Trial name
- NCT00002601
- Testing
- filgrastim, cisplatin, doxorubicin hydrochloride
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- City of Hope Medical Center
Postpartum Disorder
Effect of KT Taping on Waist-to-hip Ratio, Abdominal Strength and Body Image Concerns in Postpartum Females.
This study is aimed at determining the effect of kinesio taping on waist to hip ratio, abdominal muscle strength and body image concerns in postpartum females.
- Trial name
- NCT05010837
- Testing
- Kinesio taping with abdominal exercises, Abdominal exercises
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Riphah International University
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