Clinical trials: Muscle Damage
Cerebral Palsy, Spastic, Gait Disorders, Neurologic
Effects Of Kinesio Taping On Balance, Functionality, And Participation In Children With Cerebral Palsy?
BACKGROUND: Walking and balance problems are among the most common problems in individuals with cerebral palsy (CP). Hip abduction and extension muscle function insufficiencies are common in children with CP.
- Conditions
- Cerebral Palsy, Spastic, Gait Disorders, Neurologic, Hemiplegic Cerebral Palsy
- Trial name
- NCT04932538
- Testing
- Kİnesio Taping
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Ondokuz Mayıs University
Cerebral Palsy
Transcutaneous Diaphragmatic Electrical Stimulation and Pulmonary Function in Non-Ambulatory Cerebral Palsy
Does transcutaneous diaphragmatic electrical stimulation (TDES), added to a 6-week structured multimodal rehabilitation program, improve diaphragm function, head-neck control, and sitting balance in children with cerebral palsy…
- Trial name
- NCT07622875
- Testing
- Multimodal Rehabilitation, Transcutaneous diaphragmatic electrical stimulation (TDES)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Ankara Etlik City Hospital
Cerebral Palsy, Spastic Diplegia
MEOPA to Improve Physical Therapy Results After Multilevel Surgery
Children with cerebral palsy commonly undergo "multilevel surgery", meaning several lower limb combined procedures performed during the same surgical intervention.
- Conditions
- Cerebral Palsy, Spastic Diplegia, Quadriplegia, Hemiplegia
- Trial name
- KINOPA (NCT00632528)
- Testing
- MEOPA, Medicinal air
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cerebral Palsy, Muscle Spasticity
Effect of Botox and Vibration on Bone in Children With Cerebral Palsy
Cerebral palsy (CP) is a neuromuscular disorder that affects approximately 800,000 individuals in the U.S. An estimated 70-80% of these individuals have spasticity which affects ambulation and requires management.
- Trial name
- NCT01803464
- Testing
- Low-magnitude vibration, Botox
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Delaware
Cerebral Palsy, Central Nervous System Diseases
Power Training Combined With Interval Treadmill Training
Ambulatory children with cerebral palsy (CP) experience walking limitations which negatively influence their ability to physically participate in day to day life.
- Conditions
- Cerebral Palsy, Central Nervous System Diseases, Brain Damage, Chronic
- Trial name
- PT³ (NCT03625570)
- Testing
- Power training combined with interval treadmill training, Strength training combined with traditional treadmill training
- Where
- 2 sites in United States
- Volunteers
- 44 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Cerebral Palsy, Developmental Delay
Endermotherapy for Children With Developmental Disabilities
Children with developmental disabilities often sustain decreased range of motion in their extremities. The decrease in flexibility may be due to neuromuscular disorders such as spasticity or dystonia.
- Trial name
- NCT01207570
- Testing
- Endermotherapy, Passive manual stretching
- Where
- Hong Kong
- Volunteers
- 54 people
- Sponsor
- The Hong Kong Polytechnic University
Children, Adult, Spastic Cerebral Palsy
Full-spectrum Medical Cannabis for Treatment of Spasticity in Patients With Severe Forms of Cerebral Palsy
The proposed study is a double-blind, placebo-controlled, cross over study on 60 children aged 5 to 25 years with severe spasticity related to cerebral palsy (CP), level IV and V with full-spectrum medical cannabis product of…
- Conditions
- Children, Adult, Spastic Cerebral Palsy, Quality of Life, Cannabis
- Trial name
- HemPhar (NCT04634136)
- Testing
- Lab tests, ECG, Cannabinoid Levels
- Where
- 2 sites in Slovenia
- Volunteers
- 55 people
- Sponsor
- University Medical Centre Ljubljana
Cerebral Palsy
A Prospective Study of Two Home Based Muscle Strengthening Programs for Children With Cerebral Palsy
The aim of this randomized, stratified, single-blinded study is to compare two home based strength-training protocols (High Intensity Interval Training and Progressive Resistance Training) and their effects on muscle strength…
- Trial name
- NCT02319122
- Testing
- High Intensity Interval Training, Progressive Resistance Training
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Svehlik Martin, MD PhD
Hemiparesis, Paraparesis
Immediate Effects On Gait and Spasticity After The Use Of Passive Kinesiotherapy Equipment In The Lower Limbs Of Neurological Patients
Undergo assessment of muscle tone (Ashworth Scale), gait (BAIOBIT) and risk of falling (Timed Up and Go) before using the device; Use the device on the spastic lower limb(s) for 30 minutes; Go through the same assessment carried…
- Conditions
- Hemiparesis, Paraparesis, Tetraparesis, Cerebral Palsy
- Trial name
- NCT06696040
- Testing
- Passive mobilization using a device
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Fernanda Trubian
Cerebral Palsy, Muscle Spasticity
Dysport® Pediatric Lower Limb Spasticity Study
The purpose of this research study is to determine whether Dysport® is effective in the treatment of increased stiffness of the calf muscles and to evaluate the safety of this treatment in children with Cerebral Palsy.
- Conditions
- Cerebral Palsy, Muscle Spasticity, Children
- Trial name
- NCT01249417
- Testing
- Botulinum toxin type A
- Where
- 29 sites in United States, Chile and 4 more
- Volunteers
- 241 people
- Sponsor
- Ipsen
Spastic Cerebral Palsy
Homebased (6-week) Stretching Intervention in Children With Spastic Cerebral Palsy
This study will investigate the effect of a 6-week stretching intervention, consisting of a combination of a 2-week casting period and a home-based stretching program of the plantar flexors and hamstrings, on muscle and tendon…
- Trial name
- NCT04904094
- Testing
- Casting of the lower limb and homebased stretching exercise program.
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cerebral Palsy, Arthrogryposis
Effects of Power Mobility on Young Children With Severe Motor Impairments
The purpose this study is to determine the effects of power mobility on the development and function of young children of young children whose severe physical disabilities limit their exploratory behaviors and may unnecessarily…
- Conditions
- Cerebral Palsy, Arthrogryposis, Spinal Muscular Atrophy, Other Central Nervous System or Musculoskeletal Disorders
- Trial name
- NCT01028833
- Testing
- Power mobility
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of Oklahoma
Cerebral Palsy
Botulinum Toxin Efficiency on Spasticity of Rectus Femoris and Semitendinosus Muscles as Functional Agonist and Antagonist Muscles
The aim of the study is to confirm the functional improvement obtained through treatment of spasticity on 2 agonist and antagonist muscles.
- Trial name
- NCT00133861
- Testing
- Botulinum toxin
- Where
- France
- Volunteers
- 23 people
- Sponsor
- Hospices Civils de Lyon
Cerebral Palsy
Utility of Upper-Extremity Plyometrics in Children With Unilateral Cerebral Palsy
This study was set out to evaluate the effect of a 12-week upper extremity plyometric exercise (Plyo-Ex) on muscle strength and upper extremity function in children with hemiparetic cerebral palsy (Hemi-CP).
- Trial name
- NCT06980246
- Testing
- Plyometric Exercise, Standard exercise program
- Where
- Saudi Arabia
- Volunteers
- 58 people
- Sponsor
- Cairo University
Cerebral Palsy, Muscle Hypertonia
Evaluation of the Effect of the Presence Of Clowns on Pain and Anxiety Seen During Injections Botulinum Toxin in Child
In children requiring botulinum toxin injections, improving supervisory procedures of injection sessions to reduce pain and improve the experience of this invasive procedure is needed.
- Trial name
- CLOWN-TOX (NCT03149263)
- Testing
- distraction
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Cerebral Palsy, Spasticity, Muscle
Shock Wave Therapy for Management of Spasticity in Patients With Cerebral Palsy
Spasticity is the most common motor disorder in cerebral palsy (CP). The objectives of his therapeutic approach include; reducing pain, ease of use of orthopedic aids, improving posture, minimizing contractures and deformity, and…
- Conditions
- Cerebral Palsy, Spasticity, Muscle, Extracorporeal Shock Wave Therapy
- Trial name
- NCT05702606
- Testing
- Radial extracorporeal shock wave therapy (rESWT)
- Where
- Spain
- Volunteers
- 73 people
- Sponsor
- Fundacio Aspace Catalunya
Cerebral Palsy (CP), Spasticity
Effects Of Dry Needling On Mobility Among Children With Cerebral Palsy
This study explores the potential of dry needling as a treatment for spasticity in the foot among children with cerebral palsy (CP).
- Conditions
- Cerebral Palsy (CP), Spasticity, Range of Motion, Functional Mobility
- Trial name
- DRYSPARC (NCT06661421)
- Testing
- Dry Needling, Cerebral Palsy conventional Treatment
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Riphah International University
Spastic Cerebral Palsy
Therapeutic Potential of Myofascial Structural Integration in Children With Cerebral Palsy
The investigators hypothesize that children with spastic cerebral palsy will show greater improvements in gross motor function, associated developmental skills and growth after the 3 months of myofascial structural integration…
- Trial name
- NCT01815814
- Testing
- Rolfing / Myofascial Structural Integration
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Stanford University
Cerebral Palsy
Effects of Flywheel Exercise on Muscle and Walking Function in Teenagers and Young Adults With Cerebral Palsy
The main purpose of this project is to improve physical function and muscle health in teenagers and young adults with cerebral palsy (CP) by using an eccentric-overload resistance exercise model Specific aims 1.
- Trial name
- CP-Flywheel (NCT03124628)
- Testing
- Flywheel resistance exercise, Weight-stack resistance exercise
- Where
- Sweden
- Sponsor
- Karolinska Institutet
Spastic Cerebral Palsy, Physical Therapy Modalities
Effectiveness of Whole-Body Vibration
Cerebral Palsy is the most common cause of severe physical disability in childhood and may present difficulties and limitations that will have an impact on their independence and integration in all social areas.
- Conditions
- Spastic Cerebral Palsy, Physical Therapy Modalities, Vibration; Exposure, Lower Extremity Weakness, Spastic
- Trial name
- WBVibration (NCT06330311)
- Testing
- Physiotherapy
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad Complutense de Madrid