Clinical trials: Nebulization
Acute Bronchiolitis Due to Respiratory Syncytial Virus
Comparative Efficacy of Hypertonic Saline vs Adrenaline Nebulization in Acute Bronchiolitis
The goal of this clinical trial is to compare the efficacy of hypertonic saline nebulization with adrenaline nebulization in the treatment of acute bronchiolitis in children.
- Trial name
- children (NCT06267118)
- Testing
- Hypertonic Saline Solution, 1 Ml, Adrenaline
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Combined Military Hospital, Pakistan
Asthma
Study to Assess the Efficacy of Ipratropium Bromide Associated With High Dose Salbutamol by Repeated Nebulisation Versus Repeat Nebulisation of Salbutamol Alone, in Acute Asthmatic Attacks in Young Children
To determine whether addition of ipratropium bromide to salbutamol nebulisations produces significantly greater bronchodilation in young children presenting to an emergency department with an acute attack of asthma
- Trial name
- NCT02235428
- Testing
- Ipratropium bromide, Salbutamol
- Volunteers
- 3 people
- Sponsor
- Boehringer Ingelheim
Fear is a Common Psychological Response Undergoing Medical Procedures,Act From Uncertainty, Anticipation of Pain, Loss of Control, Previous Negative Experiences
(Effect of Toy Nebulizer Versus Distraction Cards on Children's Fear and Parental Satisfaction During Nebulization Therapy: A Comparative Study
Goal To compare the effectiveness of a toy nebulizer versus distraction cards in reducing fear among children during nebulization therapy while improving parental satisfaction.
- Trial name
- NCT07417839
- Testing
- distraction card, Nebuliser toy
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- University of Baghdad
NEBULIZATION, Children
Video Games and Mask Painting on During Nebulizer Application in Children
The clinical features of respiratory system diseases seen in childhood are generally moderate and improve in a short time. Respiratory system diseases are divided into two as upper respiratory system diseases and lower…
- Trial name
- NCT06755918
- Testing
- Control, Video game, Mask painting
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Semra Kose
Cystic Fibrosis
PEP and O-PEP Device for Nebulization in Cystic Fibrosis
Physiotherapy is an essential element in the comprehensive treatment of patients with cystic fibrosis. In symptomatic individuals, from a respiratory system perspective, it should be performed regularly, as it directly…
- Trial name
- NCT06964074
- Testing
- Nebulization with OPEP device, Nebulization with PEP device, Nebulization with Pari LC Sprint
- Where
- 2 sites in Poland
- Volunteers
- 70 people
- Sponsor
- National Institute for Tuberculosis and Lung Diseases, Poland
Upper Resp Tract Infection, Rhinitis Acute
Evaluation of a Hypertonic Seawater Aerosol Therapy Solution in Adults and Children
The purpose of this study is to evaluate the tolerance, the performance and safety of this device, 22‰ Hypertonic seawater aerosol therapy solution in unidose container, to treat adult and peadiatric patients with of upper…
- Conditions
- Upper Resp Tract Infection, Rhinitis Acute, Rhinopharyngitis, Cold Symptom
- Trial name
- AIR (NCT07267689)
- Testing
- Treatment (22‰ Hypertonic seawater aerosol therapy solution)
- Where
- 4 sites in Poland
- Volunteers
- 110 people
- Sponsor
- Laboratoires Gilbert
Cystic Fibrosis
A Study Comparing the Efficacy and Tolerability of Tobrineb®/Actitob®/Bramitob® Versus TOBI®
The objectives of the study are to demonstrate that Tobrineb®/Actitob®/Bramitob® is non-inferior to TOBI® in the primary efficacy variable, forced expiratory volume in one second (FEV1) percent of predicted normal, and to compare…
- Trial name
- CT03 Core (NCT00885365)
- Testing
- tobramycin / Bramitob, tobramycin / TOBI
- Where
- 44 sites in Czechia, France and 6 more
- Volunteers
- 324 people
- Sponsor
- Chiesi Farmaceutici S.p.A.
Non-Pharmacological Interventions, NEBULIZATION
The Effect of Using the Popit Toy and Stress Ball During Inhaler Therapy in Children
The goal of this clinical trial is to evaluate whether using a popit toy and a stress ball as distraction methods during inhaled medication administration can reduce anxiety, fear, and negative emotional responses and improve…
- Trial name
- NCT07827781
- Testing
- Intervention 1 Popit toy, Intervention 2 Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people
- Sponsor
- Izmir Katip Celebi University
Bronchiolitis
Heliox-Driven Racemic Epinephrine in Treatment of Bronchiolitis in Pediatric ED Patients
The purpose of this study is to assess whether children with moderate to severe bronchiolitis treated with standard racemic epinephrine therapy via 70:30 helium-oxygen (heliox) driven nebulization will have improvements in…
- Trial name
- NCT00116584
- Testing
- heliox, oxygen
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Preterm Birth, Respiratory Distress Syndrome
Surfactant Nebulization for the Early Aeration of the Preterm Lung
Respiratory distress syndrome is the most common cause of respiratory failure in preterm infants. Treatment consists of respiratory support and exogenous surfactant administration.
- Conditions
- Preterm Birth, Respiratory Distress Syndrome, Surfactant Deficiency Syndrome Neonatal
- Trial name
- SUNSET (NCT04315636)
- Testing
- Surfactant nebulisation
- Where
- Switzerland
- Volunteers
- 32 people
- Sponsor
- University of Zurich
Asthma
Nebulized Magnesium Sulfate as an Adjunct to Standard Therapy in Asthma Exacerbation
The purpose of this study is to investigate the effectiveness of nebulized magnesium sulfate in patient with moderate to severe asthma exacerbation in pediatric emergency
- Trial name
- NCT02584738
- Testing
- Nebulized Magnesium Sulfate, Nebulized isotonic saline, Nebulized Salbutamol
- Where
- Mexico
- Volunteers
- 152 people
- Sponsor
- Hospital General Naval de Alta Especialidad - Escuela Medico Naval
Heparin
The Effect of Heparin on Inhalation Injury
This is a prospective randomized clinical trial about the efficacy of heparin nebulization on lung injury score in inhalation burn injury in Mothary burn hospital.
- Trial name
- NCT01454869
- Testing
- standard care, Heparin
- Where
- Iran
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Asthma in Children
Budesonide/Formoterol Turbuhaler® Versus Terbutaline Nebulization as Reliever Therapy in Children With Moderate Asthma Exacerbation
Combined use of inhaled corticosteroids and long-acting β-agonists (LABAs) as the controller and the quick relief therapy termed single maintenance and reliever therapy (SMART) is a potential therapeutic regimen for the…
- Trial name
- ASTHMAFAST (NCT04705727)
- Testing
- Budesonide Formoterol Drug Combination, nebulisation of terbutaline
- Where
- 8 sites in France
- Volunteers
- 102 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Asthma in Children
Efficacy and Safety of Continuous Versus Intermittent Nebulization of Salbutamol in Acute Severe Asthma in Children Under 12 Years of Age
Asthma affects around 260 million people globally, causing around 0.5 million deaths annually. Pediatric asthma remains a major global public health challenge, significantly affecting the quality of life for many children.
- Trial name
- NCT06754631
- Testing
- Continuous Nebulization of Salbutamol, Intermittent Nebulization of Salbutamol
- Where
- 2 sites in Pakistan
- Volunteers
- 120 people
- Sponsor
- Muhammad Aamir Latif
Cystic Fibrosis
Evaluation of the Timing of the Nebulization Related to the Physiotherapy Session
The purpose of this study is to determine the optimal time for the nebulization depending on the respiratory physiotherapy session in cystic fibrosis patients.
- Trial name
- NCT02201082
- Testing
- Airway clearance technique, Amikacin nebulization
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Asthma
Dose-Ranging Study of LQ036 Single-Domain Antibody Nebulization Solution in Poorly Controlled Asthma
What is the goal of this study? The goal of this clinical trial is to find out whether the study drug LQ036 (a nebulized solution taken by inhaling through a nebulizer) works to improve lung function and asthma control in people…
- Trial name
- NCT07589439
- Testing
- LQ036
- Where
- China
- Volunteers
- 216 people
- Sponsor
- Shanghai Novamab Biopharmaceuticals Co., Ltd.
Post Operative Sore Throat
Evaluation of the Efficacy of Preoperative Ketamine Nebulization on Postoperative Sore Throat Due to Tracheal Intubation for Adult Patients Under General Anesthesia, A Prospective Randomized Controlled Study
Sore throat includes specific symptoms such as dysphagia, dysphonia, hoarseness, continuous throat pain, and pharyngeal dryness.
- Trial name
- NCT05975346
- Testing
- Ketamine, saline nebulization
- Volunteers
- 80 people
- Sponsor
- Sohag University
Asthma
Salbutamol in the Pediatric Emergencies: Nebulization Estimated Via AerogeN or Jet
Controlled trial of nebulized salbutamol using jet nebulizer or vibrating mesh technology in children presenting with acute moderate to severe asthma.
- Trial name
- SIBILANT (NCT03042065)
- Testing
- vibrating Mesh nebulizer, jet nebulizer
- Volunteers
- 60 people
- Sponsor
- Centre d'Investigation Clinique et Technologique 805
Asthma
Nebulized Magnesium Sulfate in Children With Moderate to Severe Asthma
The purpose of this study is to investigate the use of magnesium sulfate nebulization in patient with moderate to severe asthma exacerbation in pediatric emergency.
- Trial name
- NCT01584726
- Testing
- Magnesium Sulfate
- Where
- 2 sites in Qatar
- Volunteers
- 400 people
- Sponsor
- Hamad Medical Corporation
Bronchial Asthma
Efficacy and Safety of Nebulised Beclomethasone Dipropionate Plus as Needed Salbutamol vs as Needed Salbutamol or as Needed Salbutamol/Beclomethasone Fixed Combination in Young Children With Asthma Symptoms
To demonstrate a superior efficacy of BDP plus rescue salbutamol suspension for nebulisation, compared to placebo plus rescue salbutamol, in the relief of symptoms of asthma in young children with persistent symptoms of asthma.
- Trial name
- NCT00497523
- Testing
- Beclomethasone dipropionate, Beclomethasone dipropionate/Salbutamol combination, Salbutamol
- Where
- 19 sites in Poland, Ukraine
- Volunteers
- 283 people
- Sponsor
- Chiesi Farmaceutici S.p.A.