Clinical trials: Neonatal Outcome
Pregnancy Complication, Aortic Dissection
PregnAncy-Related Aortic DISsEction in China
A multicenter observational study on pregnancy-related aortic dissection
- Conditions
- Pregnancy Complication, Aortic Dissection, Marfan Syndrome, Loeys-Dietz Syndrome
- Trial name
- PARADISE (NCT07672210)
- Testing
- Intervention strategies including medication or surgery
- Where
- 4 sites in China
- Volunteers
- 500 people
- Sponsor
- DeltaHealth Hospital · Shanghai
Neonatal Hyperbilirubinemia, Treatment Decisions
Bilirubin Thresholds in Preterm Infants on Neonatal Intensive CarE Units: The B-NICE Trial
Rationale: Neonatal hyperbilirubinemia is highly prevalent in very preterm infants born <30 weeks. Since 2008, uniform Dutch phototherapy thresholds for preterm infants have been used nationwide, largely based on consensus.
- Conditions
- Neonatal Hyperbilirubinemia, Treatment Decisions, Neurodevelopmental Outcome, Phototherapy
- Trial name
- B-NICE (NCT07674537)
- Testing
- Phototherapy, Exchange Transfusion
- Where
- Netherlands
- Volunteers
- 680 people
- Sponsor
- University Medical Center Groningen
Neonatal Outcomes, Pregnancy Complications, Infectious
Systematic Screening of Lower Genital Tract Infections
Introduction: The investigation of systematic screening for asymptomatic genital infections in pregnant women is justified by the relevance of these conditions in determining adverse neonatal outcomes, such as prematurity, low…
- Conditions
- Neonatal Outcomes, Pregnancy Complications, Infectious, Premature Birth, Premature Rupture of Fetal Membranes
- Trial name
- NCT07592286
- Testing
- Enhanced microbiological screening, Standard prenatal care
- Volunteers
- 250 people
- Sponsor
- Universidade Federal do Pampa
Husband Attendance, Maternal-Neonatal Outcomes
Effect of Husband Attendance on Anesthesia Performance and Maternal-Neonatal Outcomes During Elective Cesarean Section Under Spinal Anesthesia
Family-centered perinatal care has become an integral component of modern obstetric practice, emphasizing emotional support and shared parental experiences during childbirth.
- Trial name
- NCT07641751
- Testing
- Husbands will be allowed to attend the cesarean section procedure, providing emotional support to their partners., Husbands will not be permitted to attend the cesarean section procedure
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Alexandria University
Preterm Birth, Caffeine
Caffeine for Infants Born at 28 to 34 Weeks Receiving Respiratory Support
The goal of this pilot clinical trial is to test if it is possible to conduct a larger study on the use of caffeine in preterm infants who need help with their breathing.
- Conditions
- Preterm Birth, Caffeine, Neonatal Outcomes
- Trial name
- CARES-Pilot (NCT07456670)
- Testing
- Caffeine
- Where
- Canada
- Volunteers
- 62 people
- Sponsor
- Queen's University
Congenital Anomalies, Neonatal Complications
AI-Powered Neonatal Risk Assessment for Improved Perinatal Outcomes
This study aims to develop advanced artificial intelligence (AI) models that predict neonatal risks and complications based on historical multimodal health data, including ultrasound and MRI scans.
- Conditions
- Congenital Anomalies, Neonatal Complications, Perinatal Outcomes, Perinatal Outcomes of the Mother and Fetus
- Trial name
- NCT07064356
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- FetalFirst Limited
COVID-19, Pregnancy Outcomes
Impact of COVID-19 on Pregnancy Outcomes: a Systematic Review
This systematic review aims to evaluate the impact of COVID-19 on pregnancy outcomes. It synthesizes data from various studies to provide insights into the effects of the virus on maternal and fetal health.
- Conditions
- COVID-19, Pregnancy Outcomes, Maternal Health, Neonatal Health
- Trial name
- COVID-PREG (NCT06677281)
- Testing
- Systematic Review of COVID-19's Impact on Pregnancy Outcomes
- Where
- Iran
- Volunteers
- 1 people
- Sponsor
- Zahedan University of Medical Sciences
Natural Childbirth, Water Birth
Effectiveness and Safety in Maternal and Neonatal Outcomes in Water Birth.
Childbirth is a unique and non-transferable experience in the life of a woman, her partner and her family. It is a very intense process that requires accompaniment and, in the vast majority of cases, requires analgesic support in…
- Conditions
- Natural Childbirth, Water Birth, Neonatal Asphyxia, Outcome, Adverse Birth
- Trial name
- NCT06429111
- Testing
- Epidural analgesia, Immersion water
- Where
- Spain
- Volunteers
- 642 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Birth Outcome, Adverse, Labor Long
How Long Can Labor Last? Person Centred Care During Labor to Increase Safety for Women and Newborn
"How long will my labor last" is a very common question for midwives who care for women during birth. To evaluate safe labor duration largely determines management and care during birth.
- Conditions
- Birth Outcome, Adverse, Labor Long, Labor Complication, Maternal Injury
- Trial name
- NCT06420453
- Where
- Sweden
- Volunteers
- 300,000 people
- Sponsor
- Karolinska Institutet
SARS-CoV2 Infection, Neonatal Infection
Outcomes of Neonates Born to Mothers With SARS-CoV-2 Infection in Shanghai
Since March 2022, there are an outbreak of SARS-CoV-2 infection (Omicron) in Shanghai. This cohort study aims to analysis the clinical outcomes of neonates born to mothers with SARS-CoV-2 infection.
- Conditions
- SARS-CoV2 Infection, Neonatal Infection, Outcomes
- Trial name
- NCT05379452
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Children's Hospital of Fudan University
Maternal Health, Infant Health
Using Advanced Data Systems to Improve Health in Early Life in Rural Nepal
The goal of this cluster randomized controlled trial is to study the effect of a mobile-phone based application used by pregnant women on maternal and newborn health indicators.
- Conditions
- Maternal Health, Infant Health, Institutional Delivery, Birth Preparedness and Complication Readiness
- Trial name
- CITH (NCT05697822)
- Testing
- Mobile Phone and Cloud-based Electronic Contact and Recording System
- Where
- Nepal
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Amit Arjyal
Adverse Maternal and Neonatal Outcomes
Risk Factors for Pregnancy-induced Hypertension in Pregnant Patients Undergoing Cesarean Section
After Institutional Review Board approval, we performed a retrospective cohort study among all women presenting for pregnancy-induced hypertension under Cesarean section in Renji Hospital Affiliated to Shanghai Jiaotong…
- Trial name
- NCT04808375
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- RenJi Hospital
Primary Maternal and Neonatal Outcomes; Assisted Reproductive Technology
Retrospective Comparison of Pregnancy Outcome of Infertile Patients After Fresh and Warmed Single Blastocyst Transfer From 2014 to 2018.
The investigators retrospectively analysed the maternal and neonatal outcomes following a single fresh blastocyst transfer and a single warmed blastocyst transfer from procedures performed between 2014 and 2018 in a tertiary…
- Trial name
- NCT04310761
- Testing
- one single blastocyst transfer, both fresh and warmed
- Volunteers
- 4,613 people
- Sponsor
- Istituto Clinico Humanitas
Standardized Training System for Residents, Neonatal Outcomes
Associations of the Grades of Doctor and Neonatal Outcomes
In China, the standardized training system for residents was built last year, and the associations of the grades of doctors and accoucheurs and neonatal outcomes remains unclear.
- Trial name
- NCT03227302
- Testing
- attending obstetrician, associate obstetrician, chief obstetrician
- Where
- China
- Volunteers
- 20,000 people
- Sponsor
- Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Hypothermia, Neonatal Outcome
Hypothermia and the Effect of Ambient Temperature 2
Neonatal hypothermia is associated with increased risk of mortality as well as multiple morbidities. The prior HEAT study conducted at our institution showed a difference in neonatal hypothermia with a change in ambient operating…
- Conditions
- Hypothermia, Neonatal Outcome, Cesarean Section
- Trial name
- HEAT2 (NCT03008577)
- Testing
- Change in ambient operating room temperature
- Where
- United States
- Volunteers
- 5,221 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Adverse Maternal and Neonatal Outcomes
The Labor and Delivery Teamwork Intervention Trial
A cluster-randomized controlled trial was conducted at 7 intervention and 8 control hospitals to evaluate the effect of teamwork training on the occurrence of adverse outcomes and processes of care in labor and delivery.
- Trial name
- NCT00381056
- Testing
- Labor and Delivery Team Coordination Course
- Where
- 15 sites in United States
- Volunteers
- 30,000 people
- Sponsor
- Beth Israel Deaconess Medical Center