Clinical trials: Obstetrics
Collaboration
A Case Study of a Maternity Service Development Programme
BACKGROUND: In 2011 a Maternity Services Development Programme was implemented in a South of England city, to promote effective collaborative working between maternity services (midwives) and other service providers (health…
- Trial name
- NCT02628184
- Testing
- Maternity Services Development Programme
- Where
- 4 sites in United Kingdom
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Obstetrical Brachial Plexus Palsy
Deficits of Strength of the Rotator Muscles of the Shoulder in Children
The purpose of this retrospective work is to study the consequences of obstetrical brachial plexus paralysis on the rotator muscles of the shoulder.
- Trial name
- ROTPOPB (NCT03440658)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Montpellier
Obstetrical Brachial Plexus Palsy
Study of the Biological Function of Muscle Satellite Cells From Patients With Obstetric Brachial Plexus Palsy
The purpose of this prospective work is to study the consequences of obstetrical brachial plexus paralysis on the rotator muscles of the shoulder.
- Trial name
- SCOPE (NCT05403034)
- Testing
- Muscle biopsy
- Where
- France
- Volunteers
- 8 people
- Sponsor
- University Hospital, Montpellier
Preeclampsia
China Obstetrics Alliance Cohort Study
Preeclampsia (PE) is one of a common type of hypertensive disorder complicating pregnancy (HDCP). It is a class of clinical syndromes which shows relevant symptoms, hypertension and proteinuria after 20 weeks pregnant as main…
- Trial name
- NCT03615560
- Volunteers
- 1,000 people
- Sponsor
- Guangzhou Medical University
Obstetric and Perinatal Complications, Postpartum Hemorrhage
A Skills and Drills Intervention for Emergency Obstetrics and Neonatal Care at First Referral Units of North Karnataka
To evaluate the effectiveness of a First Referral Unit (FRU) Emergency Obstetric and Newborn Care (EmONC) skills and drills intervention, to estimate the appropriateness and effectiveness of referrals in intervention arm compared…
- Conditions
- Obstetric and Perinatal Complications, Postpartum Hemorrhage, Preeclampsia/Eclampsia, Obstructed/Prolonged Labor
- Trial name
- NCT01865656
- Testing
- Skills training, Emergency obstetric drills, Revised Case Sheets
- Volunteers
- 15,018 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Postpartum Period
Involving Men in Maternity Care in Burkina Faso
The uptake of postpartum contraception, postpartum care attendance and the practice of exclusive breastfeeding are low in Sub-Saharan Africa.
- Trial name
- NCT02309489
- Testing
- Partner involvement
- Where
- Burkina Faso
- Volunteers
- 1,144 people, healthy volunteers welcome
- Sponsor
- London School of Hygiene and Tropical Medicine
Patient Blood Management, Blood Product Transfusion for All Conditions
Patient Blood Management in Obstetrics
Obstetric anemia and hemorrhage are major causes of maternal morbidity and increased healthcare utilization. Although red blood cell (RBC) transfusion is commonly used, it is associated with higher rates of postpartum…
- Trial name
- PBM (NCT07544017)
- Where
- United Arab Emirates
- Volunteers
- 44,000 people
- Sponsor
- Corniche Hospital
Neonatal Complication, Labor (Obstetrics)--Complications
Can the Use of a Next Generation Partograph Improve Neonatal Outcomes? (PICRINO)
The overall aim is to evaluate the impact of the use of two different guidelines for monitoring labor progress, the WHOs LCG versus standard care, on neonatal and maternal outcomes.
- Trial name
- NCT05560802
- Testing
- WHOs Labour care guide
- Where
- 24 sites in Sweden
- Volunteers
- 120,000 people
- Sponsor
- Linkoeping University
Fatigue
Developing Models for Fatigue Monitoring in Obstetrics and Gyne- Cology Residents Using Wearables
This study is set out to observe heart-rate and related bio-metric indicators in Obstetrics and Gynecology residents during their duty hours, together with self-reporting of fatigue and tasks performances, in order to model…
- Trial name
- IoT4Resident (NCT03354871)
- Where
- Israel
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Behavior, Respect
Inclusive, Supportive and Dignified Maternity Care in Public Health Systems
Mistreatment, discrimination, and poor psycho-social support during childbirth at health facilities are common in lower- and middle-income countries.
- Trial name
- SDMC (NCT05146518)
- Testing
- Supportive and Dignified Maternity Care
- Where
- Pakistan
- Volunteers
- 310 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Educational Problems
Impact of Surgical Coaching on Resident ObGyn Laparoscopic Skills
Surgical coaching involves the development of a partnership between two surgeons in which one surgeon (coach) guides the other (coachee) in identifying goals, providing feedback and facilitating action planning.
- Trial name
- NCT05911165
- Testing
- No surgical coaching, Surgical coaching
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- The Cleveland Clinic
Preterm Delivery, Obstetrical Complications
Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial
This is a phase-III multi-center double-blind randomized clinical trial of 1,800 individuals with a history of prior preterm birth at less than 35 weeks gestation who are randomized to either 162 mg aspirin or 81 mg aspirin…
- Trial name
- ADEPT (NCT06980025)
- Testing
- 162mg Aspirin, 81mg Aspirin
- Where
- 14 sites in United States
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Obstetrical Complications, Labor and Delivery Complication
Azithromycin Prophylaxis for PRElabor CEsarean DElivery Trial
This is a phase-III multi-center double-blind randomized controlled trial of 8,000 individuals undergoing a scheduled or prelabor cesarean delivery who are randomized to either adjunctive azithromycin prophylaxis or to placebo.
- Conditions
- Obstetrical Complications, Labor and Delivery Complication, Cesarean Delivery
- Trial name
- PRECEDE (NCT06605118)
- Testing
- Azithromycin Injection, Standard of Care Preoperative antibiotics
- Where
- 14 sites in United States
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- The George Washington University Biostatistics Center
Preeclampsia
China Obstetrics Alliance Cohort Study
Preeclampsia (PE) is one of a common type of hypertensive disorder complicating pregnancy (HDCP). It is a class of clinical syndromes which shows relevant symptoms, hypertension and proteinuria after 20 weeks pregnant as main…
- Trial name
- COACS (NCT03038555)
- Where
- 5 sites in China
- Volunteers
- 900 people
- Sponsor
- The Third Affiliated Hospital of Guangzhou Medical University
Contraception, Maternal Care Patterns
Maternity Care and Contraception
This is a multicenter observational study of implementation of postpartum contraceptive counseling and provision into the maternity care setting in Colombia, South America.
- Conditions
- Contraception, Maternal Care Patterns, Pregnancy Related
- Trial name
- COMSE (NCT03389958)
- Testing
- Counseling and provision of contraception
- Where
- 3 sites in Colombia
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Prelabor Rupture of Membranes, Labor (Obstetrics)--Complications
Early V/S Delayed Induction of Labour in Patients With Prelabour Rupture of Membranes
To compare the effects of early V/s delayed induction of labour and its outcomes in patients presenting with PROM without labour.
- Conditions
- Prelabor Rupture of Membranes, Labor (Obstetrics)--Complications, Induction of Labor
- Trial name
- PROM (NCT07261332)
- Testing
- 0.5mg PGE2 gel
- Where
- Pakistan
- Volunteers
- 88 people
- Sponsor
- Laiba Qamar
Morbidity;Perinatal
Enriched Holistic Care to Eradicate Disparities in Maternal Morbidity
The goal of this randomized controlled intervention trial is to evaluate an integrated, interdisciplinary, multi-level maternity care home model (MCHM) aimed at reducing severe maternal morbidity (SMM) among a group of Black…
- Trial name
- ENHANCED (NCT06245057)
- Testing
- Maternity care home model (MCHM)
- Where
- 2 sites in United States
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Neonatal Brachial Plexus Palsy
Emergent Therapies in OBP. Pilot Study
Obstetric Brachial Palsy (OBP) produces functional limitations in the involvement of the affected upper limb within the child's natural environment.
- Trial name
- NCT04412603
- Testing
- Conventional Mirror Therapy
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CEU San Pablo University
Unexpected Delivery Outside Maternity
Observatory of Unintentional Births Hospital Extras
In France, pre-hospital unexpected birth is a rare situation, but over the last ten years, the investigators have seen an increase in the number of these.
- Trial name
- AIEH34 (NCT03820505)
- Where
- France
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Emergency Maternity Care, Health Inequalities in Maternity Care Access
Disparities In Access to the Northwest Ambulance Service During Pregnancy, Birth and Postpartum Period and Its Association With Neonatal and Maternal Outcomes
This study is the first in the United Kingdom (UK) to look at how women and families from different backgrounds use ambulance services during the 'perinatal period' - through pregnancy, birth, and shortly after having a baby.
- Conditions
- Emergency Maternity Care, Health Inequalities in Maternity Care Access, Disparities in Access to Maternity Care, Deprivation
- Trial name
- DIAAS (NCT07049263)
- Where
- United Kingdom
- Volunteers
- 18,000 people
- Sponsor
- Manchester University NHS Foundation Trust