Clinical trials: Pain Thresholds
Sensation Diminished, Pinprick, Pain
Tactile and Pain Sensory Thresholds and Hand Grip Strength
The aim of this study was to compare fingertip tactile sensation, hand and finger grip strength, and hand pain thresholds in children diagnosed with specific learning disorder with impairment in written expression and healthy…
- Conditions
- Sensation Diminished, Pinprick, Pain, Specific Learning Disorder, With Impairment in Written Expression
- Trial name
- NCT07533409
- Testing
- Treatment outcome
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Sultan 1. Murat State Hospital
Knee Osteoarthritis
Pain Compared Between the First and the Second Surgery in Staged BTKA
postoperative pain and analgesic consumption between the first and the second surgery would be compared in patients undergoing staged bilateral total knee arthroplasty (BTKA).
- Trial name
- NCT01457313
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Bundang Hospital
Cervicogenic Headache
The Effect of Myofascial Release in Patients With Cervicogenic Headache
Cervicogenic headache (CeH) is a secondary and often unilateral that is known by referring pain from soft or hard cervical structures to occipital, temporal, frontal and sometimes pre-orbital regions.
- Trial name
- RCT (NCT03113357)
- Testing
- Myofascial release technique, conventional exercise therapy
- Where
- Iran
- Volunteers
- 34 people
- Sponsor
- University of Social Welfare and Rehabilitation Science
Dysmenorrhea Primary
Effect of Aquatic Exercise Versus Aerobic Exercise on Primary Dysmenorrhea and Quality of Life in Adolescent Females
This study was conducted to determine the difference between impact of aerobic and aquatic exercise on primary dysmenorrhea and quality of life in adolescent girls.
- Trial name
- NCT06129708
- Testing
- Aquatic Exercise, Aerobic Exercise
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Tennis Elbow, Health Adult Subjects
Assessment of Pressure Pain Threshold (PPT) and Conditioned Pain Modulation (CPM) After Effect in Patients With and Without Tennis Elbow (TE)
This study at Hashemite University looks at how people with and without tennis elbow (AKA lateral elbow tendinopathy) feel pressure pain and how their bodies briefly "turn down" pain after a cold stimulus.
- Conditions
- Tennis Elbow, Health Adult Subjects, Lateral Elbow Tendinopathy (Tennis Elbow), Pressure Pain Threshold (PPT)
- Trial name
- NCT07178288
- Testing
- Physiological/measurement-validation study
- Where
- Jordan
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- The Hashemite University
Widespread Chronic Pain
Chronic Widespread Pain and White Blood Cell Activation
Our goal is to conduct a proof-of-concept trial to test the efficacy of KF treatment in adolescents with severe CWP not responding to the standard of care (SOC) treatment program in a multidisciplinary tertiary care chronic pain…
- Trial name
- NCT02984397
- Testing
- Ketotifen Fumarate, Standard of Care
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Sickle Cell Anemia
Pressure Pain Tolerance in Relation to Balance and Strength in Children
Sickle cell disease (SCD) is the most frequent life-threatening genetic hemoglobinopathy in the world and occurs due to the synthesis of abnormal hemoglobin S (HbS).Cells with sickle cell hemoglobin are stiff and sticky.
- Trial name
- NCT06529874
- Testing
- Pressure pain tolerance measurement using Digital Pressure Algometer, Balance assessment using HUMAC balance system, Lower limb muscular strength using Lafayette hand held dynamometer
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Adly A Adam
Migraine
Puberty, Sex Hormones and Pain Sensitivity in Adolescents With Migraine
The purpose of this research study is to investigate the relationships between sex hormone levels and experimental pain sensitivity and migraine severity will be examined.
- Trial name
- IHS (NCT05738213)
- Testing
- Thermal stimuli, Pressure stimuli, Pain ratings
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Somatosensory Disorders
Somatosensory Evoked Potentials and Pain Thresholds in Term and Preterm-Born Adolescents After Early Exposure to Pain; a Quantitative Study
Background: Several studies have indicated that infants who had undergone postnatal painful procedures appear to be hypersensitive to pain, with a lower threshold to tactile stimulations later on life.
- Trial name
- NCT00503100
- Testing
- Thermal stimulation
- Where
- Israel
- Volunteers
- 10 people
- Sponsor
- Soroka University Medical Center
Pain
Effect of Electroacupuncture on Pain Threshold
This study is designed to evaluate whether or not electroacupuncture can have an effect on the pain threshold of the subject, as compared to sham treatment.
- Trial name
- NCT00802165
- Testing
- Electroacupuncture
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic
Intellectual Disability
Characterization of Nociception Phenotype in Individuals With Intellectual Disability
Background: People with intellectual disability (ID) often have physical disabilities as well. These physical problems can affect their bones, muscles, nerves, and gastrointestinal tracts. All of these issues can also cause pain.
- Trial name
- NCT05473429
- Testing
- TSA2 Thermosensory Stimulator
- Where
- United States
- Volunteers
- 215 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Post-operative Pain, Acute, Pain Threshold
Cold Press Test and Post Operative Pain Relationship
The goal of this clinical trial is to investigate whether it is possible to get a preliminary idea about the postoperative pain in the patient with the results of a practical cold press test applied to American Society of…
- Trial name
- NCT05904873
- Testing
- Mandibular Third Molar Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sinem Büşra Kıraç Can
Pain
Self-reported and Experimental Pain in Patients Undergoing Orthodontic Treatment
Pressure Pain Threshold (PPT) is defined as the minimum force applied to an area that is perceived as pain. PPT is considered an objective measurement tool to assess pain levels.
- Trial name
- NCT06426238
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Midwestern University
Cardiac Surgery Subjects
Objective Measurement of the Mechanical Pain Threshold With an Algometer for Predicting Intraoperative Opioid Consumption in Patients Who Will be Operate by Thoracotomy and Sternotomy in Cardiac Surgery
The study aims to test the relationship between the preoperative pain threshold and the intraoperative need for opioids. The objective of the study is to try to predict a patient's analgesic needs based on their objectively…
- Trial name
- NCT07513974
- Testing
- Measure of the minimal pain threshold with an algometer
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Libre de Bruxelles
Transcranial Direct Current Stimulation, Working Memory
Transcranial Direct Current Stimulation Effect on Pain Threshold and Working Memory: Impact of Age and Protocol Type
Transcranial direct current stimulation (tDCS) is a non-invasive neuromodulation method which has great potential as an aid in the therapeutic management of neuropsychiatric disorders and chronic pain syndromes.
- Conditions
- Transcranial Direct Current Stimulation, Working Memory, Pain
- Trial name
- NCT04328545
- Testing
- Anodal tDCS on DLPFC, Anodal tDCS on M1
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre
Neck Pain
Acute Effects of Action Observation on Neck Pain
This study aims to assess the immediate effects of action observation therapy on the cervical muscles' strength, pain intensity, tactile acuity and pain pressure threshold in individuals with chronic nonspecific neck pain.
- Trial name
- NCT05078489
- Testing
- Action-observation therapy
- Where
- Portugal
- Volunteers
- 60 people
- Sponsor
- Aveiro University
Autism Spectrum Disorder
Participant(s) With Autism and High Pain Tolerance Treated With High Dose Naltrexone
High dose naltrexone with response gauged by pain tolerance as measured by the cold pressor test may help treat autism.
- Trial name
- NCT05100563
- Testing
- 50 mg naltrexone
- Where
- United States
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Persistent Pain After Open Inguinal Herniotomy
Variability in Thermal Thresholds in Patients With Persistent Pain After Open Inguinal Herniotomy
The study will investigate the test-retest variability of thermal thresholds in patients with persistent pain after open inguinal herniotomy.
- Trial name
- NCT01768130
- Where
- Denmark
- Volunteers
- 21 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Hematological Malignancies
Impact of Child Positioning on Pain During a Lumbar Puncture
This protocol is a pilot study on standard care. The main goal is to assess the impact of positioning on lumbar puncture process especially on pain sensitivity in children.
- Trial name
- PHIPA-PEPL (NCT02834156)
- Testing
- LP in a seated position then LP in a lying position, LP in a lying position then LP in a seated position
- Where
- France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Electroencephalography, Anesthesia, General
Validity of Pain Threshold Index in Children
Comparison of total infused dose of remifentanil between pain threshold index monitoring group and control group
- Trial name
- NCT03622242
- Testing
- Pain threshold index, Wavelet index
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Seoul National University Hospital