Clinical trials: Pain Thresholds
Neck Pain
Effects of Hatha Yoga on Chronic Neck Pain
Hatha Yoga is a traditional system of exercises, used in India for the relief of painful condition since centuries and gaining more and more interest in Europe and the US.
- Trial name
- NCT01171274
- Testing
- Hatha Yoga, Information regarding exercises and behaviour
- Where
- Germany
- Volunteers
- 58 people
- Sponsor
- Universität Duisburg-Essen
Pain
Effects of Prophylactic Massage Therapy on Pain Tolerance and Threshold
Therapeutic massage has been thought to reduce anxiety and increase relaxation in human patients.This study is meant to determine the immediate effects of therapeutic massage on pain tolerance and threshold.
- Trial name
- NCT04625335
- Testing
- No Massage Protocol, Prophylactic Therapeutic Massage
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kyle Knight
Neck Pain
Effects of Craniosacral Therapy on Chronic Neck Pain
The purpose of this randomized controlled trial is to determinate the efficacy and safety of Craniosacral Therapy in the treatment of chronic unspecific neck pain.
- Trial name
- CranioS (NCT01526447)
- Testing
- Craniosacral Therapy
- Where
- Germany
- Volunteers
- 54 people
- Sponsor
- Universität Duisburg-Essen
Electroencephalography, Anesthesia, General
Validity of Pain Threshold Index in Children
Comparison of total infused dose of remifentanil between pain threshold index monitoring group and control group
- Trial name
- NCT03622242
- Testing
- Pain threshold index, Wavelet index
- Where
- South Korea
- Volunteers
- 180 people
- Sponsor
- Seoul National University Hospital
Sciatic Nerve, Lower Extremity Pain
Effect of Sciatic Nerve Mobilization on Lower Extremity Pain Perception
This randomized controlled study aims to investigate the effect of sciatic nerve mobilization on pain perception in lower extremity peripheral nerves, specifically the tibial and common peroneal nerves.
- Trial name
- NCT07525895
- Testing
- Sciatic Nerve Mobilization
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Healthy
The Effects of a Moderate Intensity Training Program Versus a High Intensity Training Program on Central Pain Processing
Previous studies have shown that healthy individuals who take more steps per day and who spend more time on moderate- to vigorous-intensity activities exhibit better pain inhibition and less pain facilitation.
- Trial name
- ChronicPA-PAIN (NCT06207422)
- Testing
- Moderate intensity training program, High intensity training program
- Where
- Belgium
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Ghent
Manual Therapies, Neck Pain
Comparison of the Immediate Effects of Manual Therapy Techniques in Non-Specific Neck Pain
The aim of this study is to investigate the effects of manual therapy techniques on joint range of motion, pain tolerance, grip strength, and functionality in individuals with non-specific neck pain.
- Trial name
- NCT06959160
- Testing
- Atlanto-occipital manipulation, Cervical mobilization, Trigger point therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Halic University
Low Back Pain
Effects of Two Different Dry-Needling Techniques for Low Back Pain
Although dry-needling with or without manipulation has shown to be a useful technique to reduce pain in patients with low back pain (LBP), it is unclear which of these two dry-needling techniques would have a greater effect on…
- Trial name
- NCT03970486
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Texas Woman's University
Chronic Low Back Pain
The Effects Of Equal Breathing On Pain Pressure Thresholds
Recent research has found that there is moderate evidence for the use of breathing exercises for treating chronic, non-specific low back pain.
- Trial name
- EB-Pain (NCT03353142)
- Testing
- Equal Breathing
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Hamilton Health Sciences Corporation
Neck Pain, Migraine
Common Pain Mechanisms in Migraine, Migraine-Related Neck Pain, and Lower Back Pain: A Cross Sectional Study
Migraine is one of the primary headache disorders with a high prevalence worldwide, leading to significant disability and reduced quality of life.
- Conditions
- Neck Pain, Migraine, Low Back Pain
- Trial name
- NCT07567300
- Where
- Turkey (Türkiye)
- Volunteers
- 179 people
- Sponsor
- Bozok University
No Disease State or Condition
Pain Study to Assess Local Anesthetic Efficacy and Safety of CTY-5339 on Gingival Mucosal Tissue in Normal Volunteers
The purpose of this study is to determine if the topical application to gingival tissue of the combination of benzocaine and tetracaine has a longer duration of local anesthetic activity than benzocaine alone.
- Trial name
- NCT03233737
- Testing
- One spray CTY-5339-A, One spray CTY-5339-CB, One spray CTY-5339-P
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cetylite Industries
Healthy
The Effect of Nonverbal Vocalisations on Pain Tolerance
Humans produce non-verbal vocalizations (shouting, growling, screaming), laughter, ...) in various contexts that are likely to perform biological functions. and important social issues.
- Trial name
- VOCPAIN (NCT04425395)
- Testing
- Cold pressor task (CPT), Acoustic Recordings, Index measurement NOL™
- Where
- France
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Breast Cancer, Pain
Pilot Study to Evaluate the Effect of Aromatase Inhibitor Therapy on Pain Threshold in Breast Cancer Patients
Postmenopausal women who have hormone receptor positive breast cancer are typically treated with aromatase inhibitor medications, which substantially decrease the amount of estrogen produced by their bodies.
- Conditions
- Breast Cancer, Pain, Arthralgia
- Trial name
- NCT01814397
- Testing
- Anastrozole, exemestane, letrozole
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan Rogel Cancer Center
Opioid Use Disorder, Alcohol Intoxication
Pain Sensitivity, Alcohol-Induced Analgesia, and Heavy Drinking in Individuals With Opioid Use Disorder
The goal of this clinical trial is to examine whether individuals with co-occurring opioid use disorder and alcohol use (OUD+ALC) experience heightened pain sensitivity, pain-related negative affect, and greater alcohol…
- Conditions
- Opioid Use Disorder, Alcohol Intoxication, Pain
- Trial name
- NCT07894276
- Testing
- Alcohol
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- Ohio State University
Chronic Migraine
Examination of Muscle Stiffness, Tenderness and Pressure Pain Thresholds During a Cycle of Botulinum Toxin A Treatment in Chronic Migraine Patients
Preventive treatment with botulinum toxin A injections is standard care for chronic migraine and follows the PREEMPT protocol. Patients are injected at 31 locations in the frontal, corrugator and procerus muscle, the temporalis…
- Trial name
- BTACM (NCT05328687)
- Testing
- Shear wave elastography
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Headache Center
Neck Pain
Body Composition and Cervical Outcomes in Non-Specific Neck Pain
Non-specific neck pain (NSNP) is a common musculoskeletal condition that significantly affects quality of life, daily activities, and work productivity.
- Trial name
- NCT07388706
- Testing
- Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Izmir Democracy University
Low Back Pain
Immediate Effects of a Spinal Lumbar Manipulation
Non-specific low back pain is defined as a pain with no specific vertebral-related cause, such as infectious disease, tumor, osteoporosis, fracture, structural abnormality, inflammatory disease, radicular compressive syndrome or…
- Trial name
- NCT02312778
- Testing
- HVLA Manipulation
- Where
- Brazil
- Volunteers
- 24 people
- Sponsor
- Federal University of Rio Grande do Sul
Hamstring Muscle Tightness, Muscle Strength
The Effects of Instrument-Assisted Soft Tissue Mobilization in Sedentary Individuals With Hamstring Tightness
The aim of this study will be to investigate and compare the effects of static stretching exercise, Instrument Assisted Soft Tissue Mobilization (IASTM), and functional IASTM techniques on hamstring muscle shortness, pain…
- Conditions
- Hamstring Muscle Tightness, Muscle Strength, Pain Threshold
- Trial name
- NCT07091383
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Cyprus International University
Shoulder Pain
Manual Therapy in Chronic Shoulder Pain Treatment
Background: Passive oscillatory mobilizations are often employed by physiotherapists to reduce shoulder pain and increase function. However, there is little data about the neurophysiological effects of these mobilizations.
- Trial name
- NCT03416556
- Testing
- Mobilization to the glenohumeral joint, The manual contact condition, No-contact condition
- Where
- Spain
- Volunteers
- 31 people
- Sponsor
- University of Alcala
Polyneuropathies, Peripheral Nerve Injuries
Peripheral Physiological Measures as Determinants of Pain Risk
This study evaluates peripheral nervous system function using Multiple Excitability Measures (MEM) to obtain "electrophysiological pain phenotypes"
- Conditions
- Polyneuropathies, Peripheral Nerve Injuries, Peripheral Nervous System Diseases, Chemotherapy Effects
- Trial name
- DOLORiskWP51 (NCT02985294)
- Testing
- Multiple Excitability Measures of peripheral nerves
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Neuroscience Technologies SLP, Barcelona