Clinical trials: Patients Undergoing Cardiac Surgery
On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis
This Research Proposal Focuses on Evaluating the Effectiveness of a Nursing Care Protocol in Preventing Deep Vein Thrombosis (DVT) in Patients Undergoing On-pump Cardiac Surgery. The Study Will Include an Intervention Group That Receives the Nursing Protocol and a Control Group That Receives Routine
The primary focus of this research proposal is to examine the efficacy of a nursing care protocol in preventing the occurrence of deep vein thrombosis (DVT) in patients undergoing on-pump cardiac surgery.
- Conditions
- On-pump Cardiac Surgery - Prevention - Intervention - Experimental Group - Control Group - Incidence - Complications, DVT - Deep Vein Thrombosis, DVT Prophylaxis, DVT Prevention
- Trial name
- DVT (NCT07347652)
- Testing
- IPC devices facilitate venous return by simulating the physiological effects of muscle contraction, reducing venous stasis.
- Where
- Cyprus
- Volunteers
- 67 people
- Sponsor
- Near East University, Turkey
Anesthesia, Local, Analgesia
Analgesic Efficacy of Ultrasound Guided Bilateral Erector Spinae Plane Block in Pediatric.
This randomized, double-blinded, study aims to compare the efficacy of analgesia and any side effects of U/S guided bilateral Erector SpinaePlane block versus non-block t paediatric patients undergoing corrective cardiac…
- Trial name
- NCT04452656
- Testing
- bilateral erector spinae block
- Where
- Egypt
- Volunteers
- 98 people
- Sponsor
- Cairo University
Ultrasonography, Pediatrics
Intraoperative Lung Ultrasound in Pediatric Patients
Investigators hypothesized that perioperative lung ultrasound would be beneficial in pediatric patients undergoing cardiac surgery compared to those who did not receive lung ultrasound.
- Conditions
- Ultrasonography, Pediatrics, Perioperative Period, Lung
- Trial name
- LUS (NCT02535013)
- Testing
- Lung ultrasound
- Where
- South Korea
- Volunteers
- 122 people
- Sponsor
- Seoul National University Hospital
Intraoperative Awareness
The Impact of Maternal Sound on Awareness for Pediatric Patients Undergoing Cardiac Surgery
Awareness during anesthesia with intraoperative memory occurs when the patient is able to process information and produce specific responses to several stimuli.
- Trial name
- NCT02583295
- Testing
- Music sound, Maternal sound
- Where
- Egypt
- Volunteers
- 309 people
- Sponsor
- Assiut University
Delirium
The Effects of Anaesthetic Agents on Postoperative Delirium
The purpose of this study is to prove the correlation between the post-operative delirium (POD) and anesthetic agents. The investigators hypothesized that intravenous anaesthetics would show the lower incidence of POD, compared…
- Trial name
- NCT02374177
- Volunteers
- 292 people
- Sponsor
- Konkuk University Medical Center
Patients Undergoing Surgery for Congenital Heart Disease
Incidence, Risk Factors, and Risk Model of Acute Kidney Injury in Pediatric Patients Who Undergoing Surgery for Congenital Heart Disease
Acute kidney injury (AKI) is a major complication after cardiac surgery and has been reported to be associated with adverse outcome.
- Trial name
- NCT02081235
- Testing
- surgery for congenital heart disease
- Where
- South Korea
- Volunteers
- 220 people
- Sponsor
- Samsung Medical Center
CHD - Congenital Heart Disease
Bilateral Ultrasound Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block
Group (A): This group will receive fentanyl infusion at a dose of (0.5μg/kg/h) all through the whole operation plus ultrasound guided bilateral superficial parasternal intercostal Plane block which will be done by injecting…
- Trial name
- NCT06958120
- Testing
- superficial parasternal intercostal Plane block, Erecto spinea plane block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Acute Kidney Injury
Preventing Acute Kidney Injury (AKI) in Pediatric Patients
The purpose of this study is to compare the effects of peri-operative administration of Aminophylline versus Saline placebo in the preservation of renal function and the attenuation of renal injury in pediatric patients…
- Trial name
- AKI (NCT03897335)
- Testing
- Aminophylline
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Le Bonheur Children's Hospital
Congenital Heart Disease
Comparison of PRISM III, PIM2 and PELOD Scoring Systems
PRISMIII(Pediatric Risk of Mortality III), PIM2(Pediatric Index of Mortality 2) and PELOD(Pediatric Logistic Organ Dysfunction) are frequently used for predicting mortality and morbidity in general pediatric ICUs(Intensive Care…
- Trial name
- NCT04848168
- Where
- Turkey (Türkiye)
- Volunteers
- 116 people
- Sponsor
- Antalya Training and Research Hospital
Adult Congenital Heart Disease, Cardiac Surgery
Multicenter Validation of a Predictor Model of ACHD Patients and Cardiac Surgery
This multicentre study is to validate prediction modeling for the ACHD population undergoing cardiac surgery. The validation of this prediction model will support and generalize its use as a risk stratification tool in the ACHD…
- Trial name
- NCT04787705
- Where
- Canada
- Volunteers
- 547 people
- Sponsor
- University Health Network, Toronto
Heart; Dysfunction Postoperative, Cardiac Surgery
Follow-up Study of Patients Undergoing Cardiac Surgery
Countless studies are performed to quantify the severity of heart disease and its influence on the respiratory system, checking that their heart conditions and the surgical process determine pulmonary complications, one of the…
- Trial name
- Follow-up01 (NCT02524353)
- Testing
- cardiac surgery
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Centro Universitário de Votuporanga
Acute Kidney Injury
Cost-effectiveness Analyses for the Prevention of Acute Kidney Injury in Patients Undergoing Cardiac Surgery in the UK
Multi-centre retrospective analysis of prospectively collected data with propensity matched scoring groups (AKI v/s non-AKI). Data collection from databases (or their equivalent): PATS Dendrite, Electronic Medical Records, TD-web…
- Trial name
- Cost-AKI (NCT07108634)
- Testing
- RenalGuard Therapy
- Where
- United Kingdom
- Sponsor
- The Royal Wolverhampton Hospitals NHS Trust
Heart Valve Diseases
Effect of Remote Ischemia Preconditioning on Myocardial Injury in Patients Undergoing Heart Valve Surgery
Remote ischaemic preconditioning has shown its cardiac protective effect during heart surgery including coronary artery bypass graft surgery, congenital heart disease and aneurysm.
- Trial name
- NCT01175681
- Testing
- remote ischaemic preconditioning
- Where
- China
- Volunteers
- 73 people
- Sponsor
- Sun Yat-sen University
Open-heart Surgery, Cardiopulmonary Bypass
Intravenous Phenoxybenzamine Use in Pediatric Patients Undergoing Open-Heart Surgery
Cardiopulmonary bypass is done with a machine that does the work of the heart and lungs during open-heart surgery. This study is to determine if intravenous (i.v.) phenoxybenzamine is safe.
- Trial name
- NCT00569855
- Testing
- Phenoxybenzamine
- Where
- United States
- Volunteers
- 785 people
- Sponsor
- University of Arkansas
Cardiac Surgical Procedures
Masimo CO-Oximeter Study
This is a study to evaluate the accuracy of the Masimo Rainbow SET Pulse CO-Oximeter in monitoring the hemoglobin levels of patients undergoing isovolemic hemodilution.
- Trial name
- NCT01184521
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Nationwide Children's Hospital
Hypoplastic Left Heart Syndrome, Heart Defects, Congenital
Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery
This study aims to evaluate the safety and feasibility of coronary infusion of autologous placental cord blood mononuclear cells during the Norwood heart operation in newborn hypoplastic left heart syndrome (HLHS) patients.
- Conditions
- Hypoplastic Left Heart Syndrome, Heart Defects, Congenital, Pediatric Disorder
- Trial name
- NCT03431480
- Testing
- Autologous Human Placental Cord Blood Mononuclear Cells
- Where
- Australia
- Volunteers
- 10 people
- Sponsor
- Murdoch Childrens Research Institute
Opioid Use, Pain, Postoperative
ESP Block in Pediatric Patients for Postoperative Analgesia
Pediatric cardiac surgery is associated with moderate to severe postoperative pain that is related to median sternotomy. In a fast-track protocol, used in modern-day cardiac surgical care, early extubation may be facilitated by…
- Conditions
- Opioid Use, Pain, Postoperative, Quality of Life
- Trial name
- ESP1 (NCT03627897)
- Testing
- Bupivacain, saline
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Cukurova University
Coronary Artery Disease
Effect of an Educational Intervention on Cardiac Patients' Participation Rate in Cardiac Rehabilitation Programs
The main aim of the study is to determine the effectiveness of an educational intervention designed to increase attendance of coronary artery bypass grafting (CABG) patients at Cardiac Rehabilitation Programs (CRPs) on actual CRP…
- Trial name
- MECRIS (NCT00356863)
- Testing
- Increasing awareness to cardiac rehabilitation programs
- Where
- Israel
- Volunteers
- 1,024 people
- Sponsor
- Sheba Medical Center
Ultrasound, Pectoral Nerve Block
Ultrasound Guided Bilateral Pectoral Nerve Block Versus Bilateral Transverse Thoracic Plane Block In Pediatric Patients Undergoing Corrective Cardiac Surgeries Requiring Cardiopulmonary Bypass Via Median Sternotomy
This randomized, double-blinded, study aims to compare the efficacy of intraoperative and postoperative pain control while using bilateral ultrasound guided the pectoral nerves (PECS) versus transversus thoracic muscle plane…
- Conditions
- Ultrasound, Pectoral Nerve Block, Transverse Thoracic Plane Block, Pediatric Patients
- Trial name
- NCT06984276
- Testing
- Control, Pectoral nerves (PECS), Transversus thoracic muscle plane block (TTPB)
- Where
- Egypt
- Volunteers
- 81 people
- Sponsor
- Cairo University
Gradient Between Radial and Central Aortic Pressure After Cardiopulmonary Bypass
Evaluation of Aortic-Radial Blood Pressure Gradient in Pediatric Patients Undergoing Cardiac Surgery With Cardiopulmonary Bypass
Invasive blood pressure monitoring is essential during heart surgery. Usually, doctors measure blood pressure using a small tube (a catheter) placed in an artery, typically in the wrist or arm.
- Trial name
- GARP (NCT07857811)
- Testing
- Placement of a pressure transducer at the accessory port of the CPB arterial cannula
- Where
- 2 sites in Chile
- Volunteers
- 100 people
- Sponsor
- Pontificia Universidad Catolica de Chile