Clinical trials: Patients With Speech Disorders
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Learning Disorder, Specific, Learning Disability
Examining the Medium-term Effect on Non Inferiority of the Previous Training With the DMD Poppins Clinical for Cognitive, Musical Training in Addition to Bi-monthly Speech and Reading Therapy on Reading Writing Abilities of Pediatric Patients With SLD Reading VS Control Group
Poppins-02-b is an observational follow-up study examining the medium-term effect on non-inferiority of the previous training with the digital medical device (DMN) Poppins Clinical for cognitive and musical training in addition…
- Conditions
- Learning Disorder, Specific, Learning Disability, Specific Learning Disorder, With Impairment in Reading, Dyslexia
- Trial name
- POPPINS-02-B (NCT06902610)
- Testing
- Poppins Clinical
- Where
- 2 sites in France
- Volunteers
- 306 people
- Sponsor
- Poppins
Velopharyngeal Insufficiency in Children With Isolated or Combined Cleft Palate
Prospective Evaluation of Speech Function Through Patient- and Parent-response Outcome Measurements in Velopharyngeal Insufficiency
Cleft lip and/or palate (CL/P) is the most common congenital malformation, with about one in 500 children born with CL/P in Sweden, corresponding to approximately 175 births annually.
- Trial name
- NCT05838261
- Testing
- Pharyngeal flap
- Where
- 6 sites in Sweden
- Volunteers
- 50 people
- Sponsor
- Umeå University
Velopharyngeal Insufficiency, Articulation Disorders
Efficacy of an Arabic Articulatory Error Remediation Software Program in Patients With Velopharyngeal Valve Dysfunction:
To develop a remediation software program that is specific for correcting speech errors in patients with velopharyngeal dysfunction in the Arabic language and test its efficacy, on one group comparing pre and post results
- Conditions
- Velopharyngeal Insufficiency, Articulation Disorders, Hypernasality Syndrome Due to Velopharyngeal Weakness
- Trial name
- NCT04392817
- Testing
- Arabic Articulatory Error Remediation software program
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Alaa Mamdouh
Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis)
Music Therapy Protocol to Support Bulbar and Respiratory Functions in ALS
This study evaluates potential of music therapy treatment to support breathing, speech, swallow and cough of persons with amyotrophic lateral sclerosis (ALS).
- Conditions
- Motor Neuron Disease, Amyotrophic Lateral Sclerosis, ALS (Amyotrophic Lateral Sclerosis), Dysarthria, Flaccid, Dysarthria, Spastic
- Trial name
- NCT03604822
- Testing
- Music therapy
- Where
- 2 sites in Russia, United Kingdom
- Volunteers
- 8 people
- Sponsor
- Alisa Apreleva
Deafness
Neurophysiological Measures of Auditory Perception and Rehabilitation in Cochlear Implanted Patients
This study aims at investigating new automatic fitting techniques for cochlear implant patients based on objective measures. For this reason, the evolution of these neurophysiological measures, expressing the encoding of pure…
- Trial name
- NEUROSYLLABIC (NCT02323256)
- Testing
- Auditory steady-state response ASSR, Speech-ABR, Acoustic Change Complex ACC
- Where
- France
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Cerebral Palsy
Speech Therapy Settings in Cerebral Palsy
Cerebral palsy (CP) is a common neurodevelopmental disorder affecting motor functions, cognition, and communication skills in children.
- Trial name
- NCT07784790
- Testing
- Hospital-based Speech and Language Therapy, Home-based Speech and Language Therapy
- Volunteers
- 52 people
- Sponsor
- Selcuk University
Cleft Lip and/or Palate, Speech Disorder
Neural Changes After Speech Therapy in Patients With Cleft Palate: A Brain Imaging Study
Cleft palate is one of the most common maxillofacial congenital malformations, which results in severe speech disorders. Compensatory articulation disorder, also known as non-oral articulation disorder (NOA), is considered as the…
- Conditions
- Cleft Lip and/or Palate, Speech Disorder, Speech Therapy, Brain
- Trial name
- fMRI-Speech-CP (NCT07330687)
- Testing
- Structured Speech Training for Decompensation
- Where
- China
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Shufan Zhao
Cleft Palate
Semi-occluded Vocal Tract Exercise in Velopharyngeal Dysfunction in Patients With Cleft Palate
Analyze the effect of SOVTE (Semi-occluded Vocal Tract Exercise), with high resistance tube, on the velopharyngeal mechanism, for speech rehabilitation of twelve patients with cleft palate with vocal alterations, after four…
- Trial name
- NCT03966482
- Testing
- Group before-after
- Volunteers
- 12 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Dentofacial Abnormalities, Dentofacial Deformities
Orthognathic Speech Pathology: Phonetic Contrasts of Patients With Dental Discrepancies Pre- and Post-Treatment Analyses
The investigators are studying how speech is effected by jaw and tooth position in jaw surgery patients. Eighty percent of our jaw surgery patients have speech pathologies, compared to five percent of the general population, but…
- Conditions
- Dentofacial Abnormalities, Dentofacial Deformities, Dentofacial Anomalies, Including Malocclusion, Malocclusion
- Trial name
- OSP (NCT04117360)
- Testing
- Orthognathic surgery and Orthodontics
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- University of North Carolina, Chapel Hill
Developmental Delays
Empower EI: Comparing Early Intervention Approaches to Improve Communication in Toddlers With Developmental Delays
This study is testing three ways to deliver Early Intervention (EI) services for toddlers with developmental disabilities (DD). Children enrolled in EI speech therapy will receive one of three approaches: 1.
- Trial name
- NCT07227974
- Testing
- Therapist-Delivered Early Intervention Approach, Caregiver Coaching Early Intervention Approach, Parents Taking Action
- Where
- United States
- Volunteers
- 1,269 people
- Sponsor
- Northwestern University
Glial Tumor
Sophrology Treatment for Patients With Glial Tumours Requiring Speech Therapy
Patients with brain tumours experience a loss of independence, which may occur suddenly or gradually. Communication with the patient may be rapidly impaired, due to impaired alertness, language and/or neurocognitive disorders.
- Trial name
- SOPHNEURO (NCT05189366)
- Testing
- Sophrology, Speech therapy
- Where
- France
- Volunteers
- 13 people
- Sponsor
- Institut Cancerologie de l'Ouest
Non Fluent Aphasia in Subacute Stroke
Dual Hemisphere rTMS for Rehabilitation of Post Stroke Aphasia
To investigate the therapeutic effect of dual hemisphere repetitive transcranial magnetic stimulation (rTMS) on post-stroke non fluent aphasia.
- Trial name
- NCT01850836
- Testing
- repetitive transcranial magnetic stimulation
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Assiut University
Asthma
Effectiveness of Anthroposophic Speech Therapy in Patients With Asthma
Anthroposophic therapeutic speech is a complementary method that indirectly influences breathing and uses specific vowels, consonants, syllables and metres depending on the indication.
- Trial name
- NCT02501824
- Testing
- anthroposophic therapeutic speech
- Where
- Switzerland
- Volunteers
- 49 people
- Sponsor
- University of Bern