Clinical trials: Physiological Responses
BIS, BIS-EEG
Deep Learning Framework for Continuous Depth of Anesthesia Forecasting
The integration of Artificial Intelligence (AI) in anesthesiology offers the potential to shift patient monitoring from reactive to predictive.
- Conditions
- BIS, BIS-EEG, Artifical Intelligence, Intraoperative
- Trial name
- NCT07536230
- Where
- Belgium
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Physiological Response to Exercise, Perception of Exercise Difficulty
Perception of Physical Exertion in Healthy Weight and Obese Adolescents
Little is known regarding the relationship between perceived and physiological exertion in adolescents. The purpose of this study is to investigate the association between physiological and perceptual markers of effort during…
- Trial name
- NCT01695785
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Fever, Triage
Triage Performance and Physiological Predictors of Serious Illness in Febrile Children in the Pediatric Emergency Department
This multicenter prospective observational cohort study evaluates how well the initial triage category assigned by the Turkish Ministry of Health three-level color-coded triage system (Red-Yellow-Green) predicts serious clinical…
- Conditions
- Fever, Triage, Pediatric Emergency Medicine, Serious Bacterial Infection
- Trial name
- PEDTRIAGE (NCT07739004)
- Testing
- Ministry of Health three-level color-coded triage
- Where
- 10 sites in Turkey (Türkiye)
- Volunteers
- 3,000 people
- Sponsor
- TC Erciyes University
Healthy, Athletes
An Initial Investigation Into the Effects of β-Alanine on Performance and Physiological Responses During Simulated Wrestling Matches
This research aims to investigate the effects of beta-alanine (BA) supplementation on simulated 2-day freestyle wrestling performance, as well as on exercise-induced muscle fatigue and oxidative stress in wrestlers.
- Trial name
- NCT07641907
- Testing
- Beta-Alanine (Beta-Alanine trial)
- Where
- Taiwan
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Heat Stress, Physiological Stress
Impact of Indoor Overheating on Physiological Strain in Children
Communities worldwide are experiencing increasing heat extremes that challenge the limits of human thermoregulation, particularly among vulnerable populations such as children.
- Conditions
- Heat Stress, Physiological Stress, Cognitive Change
- Trial name
- NCT07261202
- Testing
- Simulated exposure to indoor overheating
- Where
- Canada
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Aging
Physiological Responses to a Prolonged Cycling Expedition in Older Men
The aim of this study was to test the physiological response to a 2800 km cycling expedition, from Copenhagen, Denmark to Nordkapp, Norway, in a group of older male recreational cyclists.
- Trial name
- NCT02353624
- Testing
- Cycling
- Where
- Denmark
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Healthy
Brain Receptors in Sympathetic Nervous System Regulation
The purpose of this study is to investigate the role of brain receptors called alpha2-adrenoreceptors in regulating the sympathetic nervous system, which maintains the supply of blood and fuel to the body's organs in times of…
- Trial name
- NCT00029627
- Testing
- Yohimbine
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
To Assess the Impact of the HIT Intervention on Physiological Responses, To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours
The Influence of a High Intensity Physical Activity Intervention on a Selection of Health Related Outcomes: An Ecological Approach
The purpose of this study is to determine whether a High Intensity exercise intervention can elicit cardiovascular disease protection in adolescents.
- Conditions
- To Assess the Impact of the HIT Intervention on Physiological Responses, To Assess the Role of a Secondary High School as a Setting for Promoting Healthy Eating and PA Behaviours, To Determine the Associations Between CVD Risk Factors at Baseline in 15 - 18 Year Old Youth
- Trial name
- NCT01027156
- Testing
- High Intensity Exercise
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of the West of Scotland
Pain
NeoFent-I Study; Fentanyl Treatment in Newborn Infants; a Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Study
The study will assess the efficacy of fentanyl using a pharmacokinetic/pharmacodynamic (PK/PD) model where the concentration of the drug is related to effect curve (pain score change in response to standardized procedural pain).
- Trial name
- NCT03897452
- Testing
- Fentanyl (5 microgram/ml) prediluted ampoules
- Where
- Sweden
- Volunteers
- 32 people
- Sponsor
- Lund University
Autism Disorder
Triadic Interactions of Families With Autism and Oxytocin
The study will investigate the effects of an intranasal administration of oxytocin (OT) to parents of children with autism spectrum disorders (ASD) on the quality of mother-father-child interactions.
- Trial name
- TAO (NCT01912378)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Allergy Testing, Pain, Emotional Symptoms and Physiological Parameters
Pet Therapy Effects on Pain, Emotional and Physiological Responses in Children Undergoing Allergy Testing
In recent decades, the prevalence of allergic diseases, particularly respiratory allergies, has risen significantly. In childhood, house dust mites are the primary indoor allergen in infancy, while the prevalence of pollen…
- Trial name
- NCT06875999
- Testing
- animal assisted therapy
- Volunteers
- 80 people
- Sponsor
- Mehtap METİN KARAASLAN
Premature Infants
Therapeutic Touch in Premature Infants
Preterm birth is associated with increased physiological instability, stress responses, and developmental vulnerability due to immature organ systems and prolonged exposure to invasive procedures and environmental stressors in…
- Trial name
- NCT07363785
- Testing
- Therapeutic Touch
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Patient, Child
Effects of Interventions on Child's Pain, Physiological, and Psychological Responses During Venous Catheterization
The study aimed to determine the effects of virtual reality headsets and on-screen video viewing methods on physiological parameters (heart rate, oxygen saturation, and respiration), procedural pain, fear, and emotional reactions…
- Trial name
- NCT07505225
- Testing
- Virtual Reality Headset Group (VRHG), On-screen Video Viewing Group (OVVG), Control Group (CG)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ali Yıldız
Neonatal Intensive Care, Music Therapy
The Effect of Lullaby Listened to Preterm Babies in Neonatal Intensive Care Units on Physiological Parameters and Pain
Preterms who enter a different environment after the intrauterine period experience an adaptation process and may need special care due to conditions such as developmental disabilities or neurological disorders.
- Conditions
- Neonatal Intensive Care, Music Therapy, Pain Responses
- Trial name
- NCT05253625
- Testing
- Listening to a recorded lullaby.
- Volunteers
- 93 people
- Sponsor
- Izmir Tinaztepe University
Vaccine Reaction
(VIII): The Eight Study and Immunologic Response Sub-study
The study's objective is to test the hypothesis that immune system activation and subsequent systemic inflammation can be detected through continuously tracking multiple bio signals including physiologic variables (ECG, skin…
- Trial name
- NCT05237024
- Where
- 2 sites in United States, Canada
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- physIQ, Inc.
Anxiety Wounds and Injuries
Healing Through Play
Wound dressing is a common procedure for children with injuries or wounds. The procedure can cause pain, fear, and anxiety. Children may also experience changes in heart rate and breathing when they feel distressed.
- Trial name
- Healing (NCT07909798)
- Testing
- Usual Care
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Al-Zaytoonah University of Jordan
Cystic Fibrosis
Interactive Video Game Responses in Cystic Fibrosis
Cystic fibrosis (CF) is a disease that affects multiple systems, however, the accumulation of secretion in the airways contributes to the fact that pulmonary complications are the main responsible for the high rates of morbidity…
- Trial name
- Igamecf (NCT03229213)
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidade Católica do Rio Grande do Sul
Pain Management, Fear and Anxiety
Virtual Reality for Pain, Fear, and Physiological Responses During Pediatric Venous Catheterization
This study aims to evaluate the effect of two different virtual reality (VR) applications on children's pain, fear, and physiological parameters during peripheral intravenous catheterization.
- Trial name
- VR-PainKids (NCT07202468)
- Testing
- Virtual Reality
- Volunteers
- 150 people
- Sponsor
- Ege University
Exercise Training Adaptation
Physiological and Molecular Adaptations to Different Training Modalities in National-level Kayak Athletes
This interventional study evaluated physiological, molecular, and performance adaptations to different high-intensity training modalities in national-level kayak athletes.
- Trial name
- NCT07864012
- Testing
- High-Intensity Interval Training, Sprint Interval Training, Combined High-Intensity and Continuous Training
- Where
- Greece
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Body Temperature Changes, Heat Stress
Exercise Intensity and Heat Responses in Children and Youth
Little is known about how children and youth regulate body temperature during exercise in the heat compared with young adults, including whether differences in whole-body heat exchange contribute to their responses.
- Conditions
- Body Temperature Changes, Heat Stress, Child Development, Heat
- Trial name
- NCT07781592
- Testing
- Low-Intensity Exercise in the Heat, Moderate-Intensity Exercise in the Heat, Vigorous-Intensity Exercise in the Heat
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Ottawa