Clinical trials: Randomised Controlled Trial
Insomnia, Anxiety
CBT-I Versus CBT-I+ACT for Youths With Insomnia and Anxiety
Insomnia in adolescents and youth is a long-standing public health concern due to its high prevalence and association with various physical and mental health problems.
- Conditions
- Insomnia, Anxiety, Youth
- Trial name
- NCT06156306
- Testing
- CBT-I, CBT-I combined ACT
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Cannabis, Schizophrenia
Family Motivational Intervention in Schizophrenia
Cannabis use by people with schizophrenia is associated with family distress and poor clinical outcomes. Therefore, an Family Motivational Intervention (FMI) was developed to help parents to motivate their child with a diagnoses…
- Trial name
- FMI (NCT01167556)
- Testing
- Family Motivational Intervention
- Where
- Netherlands
- Volunteers
- 147 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pneumococcal Vaccines
Wyeth Study To Evaluate a 13-valent Pneumococcal Conjugate Vaccine in Infants
The purpose of this study is to assess the safety, tolerability and immunogenicity of manufacturing scale 13-valent pneumococcal conjugate (13vPnC) vaccine compared to pilot scale 13vPnC in healthy infants when given with routine…
- Trial name
- NCT00464945
- Testing
- 13-valent Pneumococcal Conjugate Vaccine
- Where
- 9 sites in Poland
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Wyeth is now a wholly owned subsidiary of Pfizer
Local Anesthesia
Effectiveness of Sodium Bicarbonate Buffered Anaesthetic Solution on Pain During Injection
This study will test the effectiveness of addition of Sodium Bicarbonate as a buffering agent to the anaesthetic solution on minimizing the pain of injection and increasing the onset time and potency of the anaesthetic solution…
- Trial name
- NCT05473819
- Testing
- Buffered Local Anesthesia, Conventional Unbuffered Local Anesthesia
- Where
- Egypt
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Tramadol for Labor Analgesia
Tramadol for Labor Analgesia: a Placebo Controlled Randomised Control Trial
Tramadol for labor analgesia: a low risk placebo controlled randomised control trial
- Trial name
- NCT02999594
- Testing
- Tramadol Hydrochloride, Distilled Water
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Maulana Azad Medical College
Parental Anxiety, Children's Safety
Randomised Controlled Trial to Investigate the Effect of Parental Presence at Intensive Care Unit to Ward Transfer Bedside Rounds on Parental Anxiety and Children's Safety
The investigators shall conduct a randomized controlled trial to investigate the effect of parental presence at transfer rounds on parental anxiety and patient safety following transfer from the Pediatric Cardiac Intensive Care…
- Trial name
- NCT01883739
- Testing
- Parental Presence at Handover Rounds
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Cortical Dysplasia
Evaluating Dietary Intervention Before surgicaL Treatment for Epilepsy
The investigators are undertaking the first European Randomised Controlled Trial (RCT) for epilepsy surgery in children with FCD type II, to prospectively evaluate the role of the KD prior to surgery in improving seizure outcome.
- Trial name
- EDIBLE (NCT02261753)
- Testing
- Classical ketogenic diet
- Where
- 15 sites in United States, Austria and 6 more
- Volunteers
- 3 people
- Sponsor
- University College, London
Malnutrition, Stunting
Controlled Trial to Test the Efficacy of Lipid-based Nutrient Supplements to Prevent Severe Stunting Among Infants
This study tests the hypothesis that infants receiving milk-powder containing fortified spread (lipid-based nutrient supplement) as a complementary food for one year have lower incidence of severe stunting (poor length gain) than…
- Conditions
- Malnutrition, Stunting, Developmental Delay
- Trial name
- LCNI-5 (NCT00524446)
- Testing
- Milk-containing fortified spread, Soy-containing fortified spread, Maize-soy flour
- Where
- Malawi
- Volunteers
- 840 people, healthy volunteers welcome
- Sponsor
- Tampere University
Dentine Caries
Effectiveness of Single and Dual Silver Fluoride Application
This is a community-based, parallel-group, double-blinded randomised controlled trial aimed at evaluating the effectiveness of single and dual applications of 38% Silver Fluoride (SF) in arresting dentinal caries among Malaysian…
- Trial name
- NCT07658690
- Testing
- 38% Silver Fluoride (Riva Star Aqua)
- Where
- Malaysia
- Volunteers
- 148 people
- Sponsor
- University of Malaya
Learning, Behaviour
The DHA (Docosahexaenoic Acid) Oxford Learning and Behaviour (DOLAB) Study
The purpose of this study is to determine whether DHA (in a daily dose of 600 mg.) will improve the behaviour and learning of normal children aged 7-9 years in mainstream state schools who are underperforming according to…
- Trial name
- DOLAB (NCT01066182)
- Testing
- DHA (docosahexaenoic acid), Sunflower oil capsules
- Where
- United Kingdom
- Volunteers
- 360 people
- Sponsor
- University of Oxford
Urinary Tract Infections in Children
Effect of Lactoferrin Supplementation on Urinary Tract Infections in Infants.
The aim of the study was to evaluate the efficacy of orally administered bovine lactoferrin (bLF) on Urinary Tract Infections in neonates and infants.
- Trial name
- NCT06109688
- Testing
- Bovine Lactoferrin
- Volunteers
- 55 people
- Sponsor
- Medical University of Lublin
Smoking Cessation, Diabete Mellitus
Smoking Intervention Among Patients With Diabetes
This study determined the prevalence of tobacco smoking among patients with diabetes and evaluated the impact of a diabetes-specific tobacco cessation intervention on tobacco cessation outcomes and on the glycaemic control, blood…
- Trial name
- NCT04864327
- Testing
- Brief smoking cessation advise
- Where
- Iraq
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Kansaa A.Ibrahim
Bronchopulmonary Dysplasia
OPTIMIST-A Trial: Minimally-invasive Surfactant Therapy in Preterm Infants 25-28 Weeks Gestation on CPAP
Trial question: Does administration of exogenous surfactant using a minimally-invasive technique improve outcome in preterm infants 25-28 weeks gestation treated with continuous positive airway pressure (CPAP)? Trial hypothesis…
- Trial name
- OPTIMIST-A (NCT02140580)
- Testing
- Minimally invasive surfactant therapy, Continuation on CPAP
- Where
- 16 sites in United States, Australia and 4 more
- Volunteers
- 486 people
- Sponsor
- Menzies Institute for Medical Research
Acquired Bleeding Disorder, Trauma
Efficacy and Safety of Activated Recombinant Human Factor VII in Severely Injured Trauma Patients
This trial is conducted in Africa, Asia, Europe, Oceania and North America. The aim of this trial is to evaluate the efficacy of activated recombinant human factor VII given in conjunction with standard therapy in the treatment…
- Trial name
- NCT01563523
- Testing
- activated recombinant human factor VII
- Where
- 9 sites in Australia, Austria and 7 more
- Volunteers
- 283 people
- Sponsor
- Novo Nordisk A/S
Pneumonia
Vitamin-D Supplementation: Impact on Severe Pneumonia Among Under-five Children
Background: Burden: Pneumonia is the leading cause of morbidity and mortality in under-five children, particularly in developing countries.
- Trial name
- Vitamin-D (NCT02185196)
- Testing
- Vitamin D3
- Where
- Bangladesh
- Volunteers
- 197 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Malaria
Effectiveness of a Community-delivered Integrated Malaria Elimination (CIME) Model in Myanmar
In Myanmar, community health workers, known as malaria volunteers, have played a key role in reducing the malaria burden in the malaria control phase, providing essential malaria services in rural areas where the coverage of…
- Trial name
- NCT04695886
- Testing
- Community-delivered Integrated Malaria Elimination (CIME) intervention model
- Volunteers
- 6,440 people, healthy volunteers welcome
- Sponsor
- Macfarlane Burnet Institute for Medical Research and Public Health Ltd
Overweight, Obesity
Early Stockholm Obesity Prevention Program (EarlySTOPP-China)
Early STOPP project promotes good health in children from early age by supporting good habits for the whole family. Our aim is to see if we can prevent overweight and obesity in children in families where parents are overweight…
- Trial name
- EarlySTOPP-CN (NCT02396784)
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Hearing Loss, Sensorineural, Hearing Loss
BEARS Training Package to Maximise Hearing Abilities in Older Children and Teenagers With Bilateral Cochlear Implants
The goal of the BEARS clinical trial is to determine whether using the directional listening training delivered via the BEARS training package for 3-months alongside usual care compared to only receiving usual care improves…
- Conditions
- Hearing Loss, Sensorineural, Hearing Loss, Deafness, Hearing Impaired Children and Adolescents
- Trial name
- BEARS (NCT05808543)
- Testing
- Both EARS training package (BEARS), Usual Care
- Where
- 13 sites in United Kingdom
- Volunteers
- 272 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Postpartum, Fatigue
Postnatal Companion Support The Effect of Education on Maternal Depression and Fatigue
In this study, it is aimed to investigate the effect of the trainings included in the content of the practical guide for postpartum supporter training companions, which will be given to the companions of women in the postpartum…
- Conditions
- Postpartum, Fatigue, Depression, Social Support
- Trial name
- NCT06505733
- Testing
- postnatal attendant training
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Depression and Self-Harm
RCT of the Clinical and Cost Effectiveness of Cognitive Behaviour Therapy (CBT) Delivered Remotely Versus Treatment as Usual in Adolescents and Young Adults With Depression Who Repeatedly Self-harm
A randomized controlled trial to test the whether remote delivery of cognitive based therapy (CBT) is clinically and cost effective when compared to treatment as usual in adolescents and young adults with depression who self-harm.
- Trial name
- eDASH (NCT02377011)
- Testing
- Problem solving cognitive behaviour therapy (PS CBT)
- Where
- 4 sites in United Kingdom
- Volunteers
- 22 people
- Sponsor
- University of Nottingham
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