Clinical trials: Randomized-controlled Trial
Unilateral Cleft Lip
Effectiveness of Rotation-advancement and Straight-line Surgical Approaches in Repairing Unilateral Cleft Lip Defect
compare different effects of Rotation-advancement based on the Millard technique and Straight-line based on Fisher modification as surgical approaches in repairing lip defect of unilateral cleft lip patients.
- Trial name
- NCT04607213
- Testing
- Advancement-rotation approach based on Millard' for repairing lip defect., Straight-line approach
- Where
- Egypt
- Volunteers
- 12 people
- Sponsor
- Hams Hamed Abdelrahman
Bacteremia
Prophylactic Antimicrobial Catheter Lock
This is a randomized, double blinded, prospective, multicenter, clinical trial of the use of Heparin versus Gentamicin as a pos-dialysis catheter lock solution.
- Trial name
- ALLOCK (NCT00571259)
- Testing
- Heparin 1000U/mL, 4% Sodium Citrate with Gentamicin 320 mcg/mL
- Where
- United States
- Volunteers
- 303 people
- Sponsor
- Satellite Healthcare
Brain Injuries
Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics
Efficacy of Nucleo CMP Forte in Traumatic Brain Injury in Pediatrics
- Trial name
- NCT04499755
- Testing
- Nucleo CMP Forte
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sherief Abd-Elsalam
Crohn's Disease, Ulcerative Colitis
Safety of Accelerated Infliximab Infusions in Patients With Inflammatory Bowel Disease (IBD)
This study aims to test the hypothesis that the accelerated infusion of infliximab is not inferior to the conventional 2 hour infusion with respect to the frequency of infusion reaction.
- Trial name
- NCT01346826
- Testing
- Standard 2 hours-infusion, Accelerated 1 hour-infusion, Accelerated 30 minutes-infusion
- Where
- South Korea
- Volunteers
- 145 people
- Sponsor
- Asan Medical Center
Attendance
Impact of Automated Calls on Pediatric Patient Attendance in Chile
Missed health care appointments present a serious challenge to patient care. Especially in government funded health systems like that of Chile, missed appointments can lead to delayed care, wasted resources, and escalating costs.
- Trial name
- Health Call (NCT02442089)
- Testing
- Health Call
- Where
- Chile
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Relation, Mother-Child, Family Conflict
Children's Learning Centers Group FNI
The purpose of this study is to compare the effects of Family Nurture Intervention in a mother-child group setting with a Standard Children's Learning Center (CLC) Program for preschool-aged children (ages 2-4.5).
- Conditions
- Relation, Mother-Child, Family Conflict, Emotional Disturbances, Behavior Problem
- Trial name
- NCT03908268
- Testing
- Family Nurture Intervention (FNI), Standard Children's Learning Center (CLC) Program
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Columbia University
Dental White Spots
Enamel Damages Following De-bracketing From Infiltrated Surfaces
Demineralisation and white-spot caries often occures during MB treatment. While resin infiltration has been proved to stop progression of enamel demineralisation, there is still a paucity of information in the literature…
- Trial name
- NCT02359318
- Testing
- Resin infiltration, Bonding and debonding of brackets.
- Where
- Chile
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- DMG Dental Material Gesellschaft mbH
Influenza, Human, Influenza a
Phase I Clinical Trial of Quadrivalent Influenza Virus Split Vaccine
This is a randomized, blinded, active-controlled phase I clinical trial to evaluate the safety and preliminary immunogenicity of the Quadrivalent Influenza Virus Split Vaccine (QIV) in subjects (aged 3 years and above).
- Conditions
- Influenza, Human, Influenza a, Influenza Type B, Influenza Viral Infections
- Trial name
- NCT06622590
- Testing
- QIV, QIV control
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Institute of Medical Biology, Chinese Academy of Medical Sciences
Intraventricular Hemorrhage
The PREMOD Trial: A Randomized Controlled Trial of Umbilical Cord Milking vs. Delayed Cord Clamping in Premature Infants
Premature babies can be very sick and have bleeding in the brain. Giving babies more blood before cutting the umbilical cord by delayed cord clamping or umbilical cord milking has been shown to reduce the risk of bleeding in the…
- Trial name
- PREMOD (NCT01866982)
- Testing
- Umbilical Cord Milking, Delayed Cord Clamping
- Where
- 3 sites in United States
- Volunteers
- 197 people
- Sponsor
- Sharp HealthCare
Ischemic Preconditioning
Upper Body Ischemic Preconditioning and Judo Performance
The goal of this clinical trial is to learn whether briefly stopping blood flow to the upper arms with inflatable cuffs before exercise (called ischemic preconditioning, or IPC) can improve judo-specific grip and pulling…
- Trial name
- NCT07912424
- Testing
- Upper-limb ischemic preconditioning
- Where
- Kazakhstan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Pain, Comfort
Virtual Reality Intervention in Children After Hypospadias Surgery
The aim of this study is to examine the effect of virtual reality glasses use on pain, comfort, and psychosocial symptoms in children after hypospadias surgery.
- Conditions
- Pain, Comfort, Psychosocial Symptoms
- Trial name
- NCT07752680
- Testing
- Virtual reality headset, routine clinical practice
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Istanbul Medipol University Hospital
Colic
Human Milk Oligosaccharide (HMO) Supplementation in Colic Management
Efficacy and tolerability of a composition comprising of HMO in a supplement format on colic management: a double-blind, randomized, placebo-controlled trial
- Trial name
- NCT05554991
- Testing
- HMO, Parental reassurance and support
- Where
- 7 sites in Italy, Spain
- Volunteers
- 5 people
- Sponsor
- Société des Produits Nestlé (SPN)
Catheterization, Central Venous
Central Line Catheterization With Flexible Tip Straight Guidewire in Small Children
The purpose of this study is to compare the differences in central venous catheter insertion time, success rate, and complication between the flexible tip straight guidewire and J-tip guidewire for ultrasound-guided central…
- Trial name
- NCT03530618
- Testing
- Flexible tip straight guidewire, J-tip
- Where
- South Korea
- Volunteers
- 88 people
- Sponsor
- Seoul National University Hospital
Skin-Picking
Treating Skin Picking With Cognitive-Behavioral Protocol in Individual and Group Format.
Skin Picking Disorder (SPD) affects 1.4-5.4% of the general population. It has a high association with anxiety and depressive symptoms.
- Trial name
- NCT03182478
- Testing
- Rothbaum protocol in individual format, Rothbaum protocol in group format
- Where
- Brazil
- Volunteers
- 55 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Respiratory Distress Syndrome, Preterm Birth
LISA vs INSURE in Extremely Low Birth Weight Infants. A Manikin Study
This is an unblinded, randomized, controlled, crossover (AB/BA) trial of surfactant treatment with LISA vs. INSURE in a manikin simulating an extremely low birth weight infant.
- Conditions
- Respiratory Distress Syndrome, Preterm Birth, Surfactant Deficiency Syndrome Neonatal
- Trial name
- NCT04944108
- Testing
- LISA approach, Insure approach
- Where
- 2 sites in Italy
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University Hospital Padova
Myopia
A Clinical Trial to Evaluate the Efficacy and Safety of Defocusing Lenses in Delaying Myopia Progression
The objective of this clinical trial was to evaluate the efficacy and safety of defocusing lenses for delaying myopia progression in children and adolescents.
- Trial name
- NCT06411717
- Testing
- Microstructure lens A, Microstructure lens B, Control group
- Where
- China
- Volunteers
- 156 people
- Sponsor
- Suzhou Care-Real Medical Technology Co., Ltd.
Teen Pregnancy, Contraception Behavior
Evaluation of an Adolescent Pregnancy Prevention Program; Relationship Smarts+ With Lessons From Mind Matters
The goal of this randomized control trial (RCT) is to assess an innovative adolescent pregnancy prevention program among youth that are at the highest risk of adolescent pregnancy, to prevent pregnancy and Sexually Transmitted…
- Conditions
- Teen Pregnancy, Contraception Behavior, Sexually Transmitted Diseases, Reproductive Health
- Trial name
- NCT05889689
- Testing
- Relationship Smarts Plus & Mind Matters, Relationship Smarts Plus alone, Preparing Adolescents for Young Adulthood (PAYA).
- Where
- United States
- Volunteers
- 945 people, healthy volunteers welcome
- Sponsor
- Trinity Church Inc.
Autism Spectrum Disorder
Telehealth-Enabled Versus In-Person Parent-Mediated Behavioral Treatment for Challenging Behaviors in Children With ASD
The purpose of the research is to determine whether parent-mediated behavior therapy for challenging behavior commonly displayed by children with autism spectrum disorder (ASD) can be as effective when delivered via telehealth as…
- Trial name
- NCT05268796
- Testing
- Behavior therapy, Psychoeducation
- Where
- 2 sites in United States
- Volunteers
- 90 people
- Sponsor
- Stanford University
Conduct Disorder
The Efficacy and Safety of Oral Oxcarbazepine 300-1200 mg/Day as Adjuvant Therapy in the Treatment of Adolescents With Impulsivity and Aggressive Behavior in Conduct Disorder This Study is Not Being Conducted in the United States.
Conduct disorder is a group of psychiatric symptoms that can include clinical characteristics of impulsivity and aggressive behavior.
- Trial name
- NCT00154362
- Testing
- Oxcarbazepine
- Volunteers
- 50 people
- Sponsor
- Novartis
Barth Syndrome
A Trial to Evaluate Safety, Tolerability and Efficacy of Elamipretide in Subjects With Barth Syndrome
A randomized, double-blind cross over trial to evaluate the safety, efficacy, and tolerability of elamipretide in subjects with Barth syndrome.
- Trial name
- TAZPOWER (NCT03098797)
- Testing
- Elamipretide
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stealth BioTherapeutics Inc.
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