Clinical trials: Reproducibility
Hemiplegia
Measurement by 2D Ultrasound of the Pennation Angle and Elasticity of Gastrocnemius Muscle
Hemiplegic adults after stroke (stroke), children and adolescents with cerebral palsy (CP) have both muscles spastic and paresis.
- Trial name
- NCT02549807
- Testing
- Muscle elasticity measure
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
SMA
Study of the Reproducibility of the French Version of the Modified SMAFRS Scale
The goal of this observational study is to evaluate the test-retest reliability of the French version of the mSMAFRS in adult patients with SMA.
- Trial name
- mSMAFRS-F (NCT07321990)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Institut de Myologie, France
Prematurity
Study of the Interprofessional Reproducibility of a Clinical Observation Scale for the Development of Very Premature Infants
The research concerns the study of the interprofessional reproducibility of a grid for observing the development of premature infants from 1 to 6 months corrected age.
- Trial name
- SPIN-NA (NCT07169110)
- Testing
- SPIN-NA Developmental Observation Grid Assessment via Home-Based Standardized Video Recording
- Where
- France
- Volunteers
- 35 people
- Sponsor
- University Hospital, Toulouse
Peripheral Bone Density
Evaluation of the XtremeCT Device for the Assessment of Bone
The research is intended to evaluate the short-term reproducibility of the XtremeCT device for measurements of peripheral bone density and bone structure in population-based volunteers from different age groups and to compare the…
- Trial name
- XtremeCT (NCT01528423)
- Testing
- XtremeCT
- Where
- United Kingdom
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Spine Disorder
Validation of the Single-item Sleep Quality Scale
The single-item sleep quality scale (SQS) allows patients to provide a self-assessment of sleep quality over a 7-day recall period without significant additional burden.
- Trial name
- SQS (NCT06612853)
- Testing
- Sleep Quality Scale (SQS), Pittsburgh Sleep Quality Index (PSQI)
- Where
- Switzerland
- Volunteers
- 240 people
- Sponsor
- Schulthess Klinik
Zonule of Zinn Abnormality, Zonular Cataract
Repeatability and Reproducibility of Lens Zonule Length Measurement Using ArcScan Insight 100
The purpose of this study is to evaluate the intra-examiner repeatability and inter-examiner reproducibility in lens zonule length measurements using very high-frequency (VHF) digital ultrasound (ArcScan Insight 100).
- Trial name
- NCT05657951
- Testing
- ArcScan Insight 100 very high-frequency digital ultrasound
- Where
- China
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Wolff-Parkinson-White Syndrome, Sudden Cardiac Death
Stress ECG Test for the Evaluation of the Risk of Sudden Cardiac Death in a Paediatric Cohort With WPW Pattern
Patients with preexcitation are at risk for sudden cardiac death. The pathogenesis is a rapid antegrade conduction of atrial fibrillation over the accessory pathway to the ventricle resulting in ventricular fibrillation.
- Conditions
- Wolff-Parkinson-White Syndrome, Sudden Cardiac Death, Risk Stratification
- Trial name
- NCT03207373
- Testing
- Stress test (ECG)
- Where
- Switzerland
- Volunteers
- 3 people
- Sponsor
- Christian Balmer
Regional Anaesthesia
Comparison of Intraneural and Extraneural Young's Modulus Using Shear Wave Elastography
The investigators would like to compare the stiffness inside and outside nerves using a special type of ultrasound imaging called shear wave elastography.
- Trial name
- NCT01903369
- Testing
- Shear Wave Elastography
- Where
- United Kingdom
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Dundee
Schizophrenia
Imaging of Brain Receptors in Healthy Volunteers and in Patients With Schizophrenia
This study will use single photon emission computed tomography (SPECT) to study brain nicotine receptors (proteins on the surface of brain cells) in healthy subjects and in patients with schizophrenia.
- Trial name
- NCT00061789
- Testing
- SPECT Imaging of Nicotinic Acetylcholine Receptors in Brain
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Near-infrared Spectroscopy, Transition, Caesarean Section
Cerebral Oximetry in Newborns - Comparing INVOS 5100c and OxyPrem vs. 1.2
Regional tissue oxygenation (cStO2) can be monitored by near infrared spectroscopy. The commercial device INVOS 5100 (COVIDIEN, Mansfield, MA, USA) and the prototype OxyPrem vs.
- Trial name
- NCT01771601
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cutaneous Squamous Cell Carcinoma, Pathology
Interobserver Variability Desmoplasia
According to the most recent guideline of the National Comprehensive Cancer Network (NCCN), desmoplasia is considered to be a very high risk factor for recurrence, metastasis and death in cutaneous squamous cell carcinoma (cSCC).
- Conditions
- Cutaneous Squamous Cell Carcinoma, Pathology, Recurrence, Metastasis
- Trial name
- NCT06020612
- Testing
- Assessment by dermatopathologists
- Where
- Netherlands
- Volunteers
- 50 people
- Sponsor
- Maastricht University Medical Center
Near Infrared Spectroscopy
Cerebral Oximetry in Newborns - Comparing INVOS 5100 and FORE-SIGHT Cerebral Oximeters
Regional tissue oxygenation (rStO2) can be monitored by near infrared spectroscopy. The commercial devices FORE-SIGHT (CASMED) and INVOS (COVIDIEN) will be used simultaneously to test for their relative sensitivity for low oxygen…
- Trial name
- NCT01665287
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Retinal Disease, Healthy
Optical Coherence Tomography Comparative Study
This study, conducted at the NIH Clinical Center and the University of Wisconsin University, will compare measurements obtained using older and newer models of a machine called an optical coherence tomography (OCT) scanner.
- Trial name
- NCT00069199
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- National Eye Institute (NEI)
Glucose Metabolism Disorders in Cystic Fibrosis
Reproducibility of Continuous Glucose Monitoring (CGM) in the Assessment of Glucose Metabolism Disorders in Children With Cystic Fibrosis
Glucose metabolism disorders in cystic fibrosis (CF-GMD) are common and have a negative clinical impact. Screening currently relies on the oral glucose tolerance test (OGTT); however, this procedure is burdensome and complex for…
- Trial name
- CGMUCODIAB (NCT07851831)
- Testing
- Continuous Glucose Monitoring, Eating Habits Questionnaire, Use of an actigraphy watch
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Hospices Civils de Lyon
Premature Birth
Reliability Testing of Silverman-Andersen Retraction Score in Preterm Infants
Depending on their gestational age, preterm infants need several weeks with different types of breathing-support due to immature development of the lungs, respiratory muscles, chest-wall and respiratory center in the brain.
- Trial name
- NCT03199898
- Testing
- Silverman-Andersen Retraction Score
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- St. Olavs Hospital
Genotyping Techniques
Spartan Cube CYP2C19 Inter Laboratory Reproducibilty Study
The study verifies that the Spartan Cube CYP2C19 System generates reproducible results under multi-variant conditions including test site (three different test sites), operators (two operators per site), testing days (five…
- Trial name
- NCT04473573
- Testing
- Spartan Cube CYP2C19 System
- Where
- 3 sites in Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Spartan Bioscience Inc.
Malocclusion
Evaluation of the Accuracy of Measurements Made on Images Taken From the Mouth for Dental Arches
The general trend in the orthodontic practice is to become digital in many aspects. Since 1980s, digital photographs have been available and they play a principal role in the orthodontic practice for documentation and diagnosis…
- Trial name
- NCT03648515
- Testing
- Plaster models, Digital Images of the dental arches, Digital images of models
- Where
- Syria
- Volunteers
- 20 people
- Sponsor
- Damascus University
Healthy
Tongue Muscular Assessment in Children (TMAC) - Reproducibility Testing
This study aims to assess intra-rater and inter-rater reliability in measuring tongue motor skills in children.
- Trial name
- NCT06464081
- Testing
- Sleep quality assessment, Anthropometry, Tongue strength assessment
- Where
- Belgium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Developing Novel Technique of Measuring C/D Ratio From Digital Stereo Optic Disc Images, Intraobserver Reproducibility of C/D Measurements
A New Reproducible Method of Measuring C/D Ratio of Digital Stereo Images of Optic Disc
Development of a novel computer software that will assist in measuring the cup/disc ratio in digital stereo optic disc images.
- Conditions
- Developing Novel Technique of Measuring C/D Ratio From Digital Stereo Optic Disc Images, Intraobserver Reproducibility of C/D Measurements, Interobserver Variability of C/D Measurements
- Trial name
- NCT01683942
- Volunteers
- 250 people
- Sponsor
- Meir Medical Center
Functional Movement Disorders, Reproducibility of Results
Aspects of Validity of the Single Leg Squat Test: A Cohort Study of Female Soccer Players.
Movement screening tests to identify deficits or poor movement quality is commonly used in soccer and other sports to assess injury, to evaluate rehabilitation goals and return to sport after injury.
- Conditions
- Functional Movement Disorders, Reproducibility of Results, Sports Medicine
- Trial name
- NCT05289284
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet