Clinical trials: Thyroid; Functional Disturbance
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Postoperative; Dysfunction Following Cardiac Surgery
Oral Triiodothyronine for Infants Less Than 5 Months & Malnourished Children Undergoing Cardiopulmonary Bypass in Indonesia
Infants and children undergoing cardiac surgery require mechanical support for circulation called cardiopulmonary bypass. The artificial pump ensures that blood flow to the body is maintained during surgical procedure on the…
- Trial name
- I-TRICC (NCT02222532)
- Testing
- Tetronine
- Where
- Indonesia
- Volunteers
- 224 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia
Hypopituitarism, Hypogonadism
Detection and Treatment of Endocrine Abnormalities in Childhood Cancer Survivors and Hematopoietic Stem Cell Transplant Recipients
This study will determine the prevalence of endocrine-related side effects in children who have been treated for cancer and establish a database and registry organized according to cancer diagnosis, treatments and endocrine side…
- Conditions
- Hypopituitarism, Hypogonadism, Thyroid Dysfunction, Bone Diseases, Metabolic
- Trial name
- NCT00504218
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Low Birth Weight Neonates
Hospital-Based Phthalate Exposure in Very Low Birth Weight Neonates
In this observational pilot project, the investigators plan to document duration and sources of exposure to plasticizers in infants born at birth weights less than 1500 grams.
- Trial name
- NCT01420029
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dialysis; Complications
Assessment of Thyroid Dysfunction in Patients Undergoing Haemodialysis at Sohag University Hospital
Thyroid dysfunction is a prevalent endocrine disorder that significantly impacts the health of patients with chronic kidney disease (CKD), particularly those undergoing dialysis.
- Trial name
- NCT07022236
- Testing
- Thyroid profile
- Where
- Egypt
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Sohag University
Pregnancy Early, Pregnancy Related
Thyroid Stimulating Hormone (TSH) Level Variations in Early Pregnancy
Retrospective comparative study comparing group 1 (TSH level 0.1-1.99 mIU/L) and group 2 (TSH level 2.0-4 mIU/L). Each group was further subdivided into primigravidae and multipara. 1527 pregnant women were included.
- Conditions
- Pregnancy Early, Pregnancy Related, Thyroid Dysfunction
- Trial name
- NCT04565873
- Testing
- TSH
- Where
- Jordan
- Volunteers
- 1,527 people
- Sponsor
- University of Jordan
Thyroid Dysfunction, Hypothyroidism
Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) COVID-19
The thyroid gland has been shown to be a common target for COVID 19 virus. Babies born to mothers positive for COVID 19 infections were noticed to have elevated thyroid stimulating hormone ( TSH ) levels on screening.
- Conditions
- Thyroid Dysfunction, Hypothyroidism, Hyperthyroidism
- Trial name
- COVID-19 (NCT05385029)
- Testing
- Thyroxine
- Where
- Saudi Arabia
- Volunteers
- 95 people
- Sponsor
- OMER B ABDELBASIT
Hypothyroidism
Maternal Hypothyroidism in Pregnancy
There is general agreement that thyroid gland function should be assessed in pregnant women. When the gland produces too little thyroid hormone (hypothyroidism), all of the woman's bodily functions slow down, and there are…
- Trial name
- NCT00818896
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Women and Infants Hospital of Rhode Island
Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1
Baby Detect : Genomic Newborn Screening
Newborn screening (NBS) is a global initiative of systematic testing at birth to identify babies with pre-defined severe but treatable conditions.
- Conditions
- Congenital Adrenal Hyperplasia, Familial Hyperinsulinemic Hypoglycemia 1, Phosphoglucomutase 1 Deficiency, Maturity Onset Diabetes of the Young
- Trial name
- BabyDetect (NCT05687474)
- Where
- Belgium
- Volunteers
- 6,824 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Liege
Thyroid, Gland; Functional Disturbance
Ultrasound and Functional Thyroid Evaluation
Thyroid disorders are most commonly concomitant with prematurity and still remains a controversial topic. The incidence of a temporary form of hypothyroidism among preterm neonates is higher than in the general population.
- Trial name
- NCT04208503
- Testing
- thyroid ultrasound
- Where
- 2 sites in Poland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Princess Anna Mazowiecka Hospital, Warsaw, Poland
Thyroid Dysfunction
Thyroid Function in Sick and Healthy Preterm Infants Admitted in NICU of Assiut University Children Hospital
Thyroid hormones are the cornerstones of a complex system that plays an important role in the growth and development of children, especially in the development of the nervous system and brain.
- Trial name
- NCT05632965
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
CKD
Thyroid Dysfunction and Dyslipidemia in Patients With Chronic Kidney Diseases
Early diagnosis of thyroid and lipid disorders by regular screening, and treatment of such disorders in CKD patients may be highly beneficial to slow progression of CKD.
- Trial name
- NCT03277911
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Spinal Muscular Atrophy, Fragile X Syndrome
Early Check: Expanded Screening in Newborns
Early Check provides voluntary screening of newborns for a selected panel of conditions. The study has three main objectives: 1) develop and implement an approach to identify affected infants, 2) address the impact on infants and…
- Conditions
- Spinal Muscular Atrophy, Fragile X Syndrome, Fragile X - Premutation, Duchenne Muscular Dystrophy
- Trial name
- NCT03655223
- Testing
- Confirmatory Testing
- Where
- United States
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- RTI International
Thyroid Dysfunction, Pregnancy Related
Hypothyroidism in Pregnancy and Neuropsychological Development in Children
Thyroid dysfunction, particularly hypothyroidism and thyroid autoimmunity, impacts a significant proportion of pregnant women, affecting 3% and 17% respectively.
- Conditions
- Thyroid Dysfunction, Pregnancy Related, Language Development
- Trial name
- OHPLDO (NCT06272721)
- Testing
- Griffiths Scale
- Where
- Italy
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Anxiety, Depression
Evaluation of Different Psychiatric Symptoms in Patients With Thyroid Dysfunction
1. Evaluate psychiatric symptoms in patients with thyroid dysfunction. 2. Investigate effect of treatment on psychiatric symptoms after 2 months.
- Conditions
- Anxiety, Depression, Thyroid Dysfunction
- Trial name
- NCT06185309
- Volunteers
- 85 people
- Sponsor
- Assiut University
Excessive Iodine Status, Thyroid Dysfunction, Antepartum
Research on Excessive Iodine Status in Pregnancy
To explore main cause and health impact of iodine excess during pregnancy, we performed iodine evaluation for 390 consecutive pregnant women from January 1st, 2016 to December 31st, 2016.
- Conditions
- Excessive Iodine Status, Thyroid Dysfunction, Antepartum, Pregnancy Related, Neonatal Disorder
- Trial name
- NCT03422406
- Testing
- Dietary iodine intake restriction
- Volunteers
- 18 people
- Sponsor
- Peking Union Medical College Hospital
Thyroid Disease, Pregnancy
Thyroid Disease in Pregnancy: Case Finding Versus Universal Screening
The purpose of this study is to determine whether treatment of thyroid disease during pregnancy decrease the incidence of adverse outcome, and to compare the impact of Universal Screening versus case Finding strategy in detecting…
- Trial name
- NCT00846755
- Testing
- Levothyroxine, Propylthiouracile
- Where
- Italy
- Volunteers
- 4,657 people, healthy volunteers welcome
- Sponsor
- Ospedale V. Fazzi
Transient Hypothyroxinemia of Prematurity
EEG Alterations in Preterm Infants With Thyroid Dysfunction
The aim of this study is to investigate differences in electroencephalography (EEG) evolution between preterm infants with and without transient hypothyroxinemia of prematurity (THOP) in order to find differences in the…
- Trial name
- EEG-THOP (NCT03493113)
- Testing
- EEG
- Where
- Belgium
- Volunteers
- 87 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Acne Vulgaris, Thyroid Dysfunction
Thyroid Dysfunction in Female Patients With Acne Vulgaris: [ Relation to Other Variables ]
Acne is a chronic inflammatory disease of the pilo-sebaceous unit with a multi-factorial etiology. It is one of the most frequent cutaneous diseases, affecting more than eighty percent of the population at some point in their…
- Trial name
- NCT03602534
- Where
- Egypt
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- Assiut University
Thyroid Dysfunction, Immune Thrombocytopenic Purpura
Study of Thyroid Dysfunction in Immune Thrombocytopenic Purpura Patients
Study of relation between thyroid dysfunction and immune thrombocytopenic purpura patients and if there is relation between them
- Trial name
- NCT07900334
- Testing
- Laboratory tests TSH, FT3, FT4 ,anti thyroglobulin antibodies, Anti -TPO antibodies
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University