Clinical trials: Type One Diabetes Mellitus
Type 1 Diabetes Mellitus
Prevalence and Incidence of Complications of Type One Diabetes in PUne At a Tertiary Care CentRE
Due to early diagnosis (<20yrs of age) of Type 1 Diabetes, patients face longer duration of disease and greater glycemic exposure which makes them more vulnerable towards chronic complications.
- Trial name
- PICTURE (NCT03069196)
- Where
- India
- Volunteers
- 323 people
- Sponsor
- Kem Hospital, Pune, India
Bone Metabolism
Efficacy of Pioglitazone on Bone Metabolism in Postmenopausal Women With Impaired Fasting Glucose.
The purpose of this study is to evaluate the effect of pioglitazone on bone metabolism in postmenopausal women with impaired fasting glucose.
- Trial name
- NCT00708175
- Testing
- Pioglitazone
- Where
- 34 sites in United States
- Volunteers
- 156 people
- Sponsor
- Takeda
Type 1 Diabetes (T1D)
Universal Type 1 Diabetes Screening in Pediatrics
This study examines how population-based screening for type 1 diabetes (T1D) using islet autoantibodies (i.e., immune system proteins) can be incorporated into pediatric primary care during routine well-child visits.
- Trial name
- NCT07612475
- Testing
- Set of implementation strategies
- Where
- 8 sites in United States
- Volunteers
- 9,500 people
- Sponsor
- Northwestern University
Diabetes Mellitus, Type 1
Behavioral Family Therapy and Type One Diabetes
Behavioral family therapy, specifically focused on insuring support for the primary caregiver of a child with type one diabetes mellitus and healthy family dynamics, may improve the child's glycemic control as measured by…
- Trial name
- NCT03720912
- Testing
- Online Learning Modules
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of California, Davis
Diabetes Mellitus, Type 1, Diabetes type1
Repeat BCG Vaccinations For The Treatment Of Pediatric Type 1 Diabetes
The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect on pediatric Type 1 diabetes.
- Conditions
- Diabetes Mellitus, Type 1, Diabetes type1, Autoimmune Diabetes
- Trial name
- NCT05180591
- Testing
- Bacillus Calmette-Guérin, Saline Injection
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Massachusetts General Hospital
Type One Diabetes Mellitus
Evaluation of a Mobile Application Designed to Support Type 1 Diabetic Patients in Adjusting Their Insulin Doses.
Title: Evaluating a Mobile Application for Insulin Management in Iraqi Type 1 Diabetes Patients. The goal of this clinical trial is to determine whether a mobile health application can improve insulin management and blood sugar…
- Trial name
- NCT07234500
- Testing
- mHealth Mobile Application, Standard Care (in control arm)
- Where
- Iraq
- Volunteers
- 50 people
- Sponsor
- University of Baghdad
Type 1 Diabetes Mellitus
One-Year Follow-up Safety Study in Subjects Previously Implanted With VC-01™
The purpose of this trial is to evaluate the long-term safety in subjects previously implanted with VC-01™ combination product.
- Trial name
- NCT02939118
- Volunteers
- 51 people
- Sponsor
- ViaCyte
Type 1 Diabetes Mellitus
Omega-3 and Vitamin D Supplements in Childhood T1D
The study was conducted in 64 patients with T1D of which 26 had the onset in 2017, and 38 in 2016, 2015 and 2014. All received vitamin D 1000 IU /day since disease's onset.
- Trial name
- NCT03911843
- Testing
- omega-3 supplementation, Vitamin D supplementation
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero Universitaria Maggiore della Carita
Diabetes Mellitus, Type 1 Diabetes
Repeat BCG Vaccinations for the Treatment of New Onset Type 1 Diabetes in Children Age 8-<18 Years
The purpose of this study is to investigate if repeat bacillus Calmette-Guérin (BCG) vaccinations can confer a beneficial immune and metabolic effect in new onset pediatric Type 1 diabetes.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Diabetes type1, Autoimmune Diabetes
- Trial name
- NCT05866536
- Testing
- Bacillus Calmette-Guérin, Saline Injection
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus
Comparative Study of a Smartphone-Linked Self-Monitoring System Versus a Traditional One for Improving Metabolic Control and Compliance to Self-Monitoring of Blood Glucose
The purpose of this study is to demonstrate the superiority of iBGstar as a component of the diabetes treatment vs. traditional blood glucose self-monitoring system for improving glycemic control after 6 months in young patients…
- Trial name
- iNew Trend (NCT02073188)
- Testing
- iBGStar, Traditional Glucometer
- Where
- Italy
- Volunteers
- 186 people
- Sponsor
- Sanofi
13-18 Year, Diagnosed at Least 6 Months Ago
Metabolic Control Adolescents Type 1 Diabetes
Purpose of the research; The aim of this study is to examine the effect of education including peer-interactive group support to be given to adolescents diagnosed with Type 1 diabetes with poor glycemic control in the 13-18 age…
- Conditions
- 13-18 Year, Diagnosed at Least 6 Months Ago, HbA1C> 7.5, Being Able to Read and Write
- Trial name
- NCT05811078
- Testing
- training sessions with peer interactive group
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Toros University
Type 1 Diabetes Mellitus
Omnipod 5 Implementation in Belgian Paediatric Diabetes Care
This study will evaluate the introduction and use of the Omnipod® 5 hybrid closed-loop insulin delivery system in children and adolescents with type 1 diabetes following its reimbursement in Belgium.
- Trial name
- O5-IMPACT (NCT07785037)
- Testing
- Tubeless Hybrid Closed-Loop Insulin Delivery System
- Volunteers
- 200 people
- Sponsor
- Queen Fabiola Children's University Hospital
Diabetes Mellitus, Type 1
Polyclonal Anti-T-Lymphocyte Globulin (ATG) in Type 1 Diabetes
The primary objective of the study is: To compare the effect of ATG treatment together with intensified insulin therapy (Group 1) on fasting and glucagon-stimulated C-peptide production with that of intensified insulin therapy…
- Trial name
- NCT00190502
- Testing
- Polyclonal anti-T-cell antibodies
- Where
- Czechia
- Volunteers
- 28 people
- Sponsor
- Institute for Clinical and Experimental Medicine
Diabetes Mellitus, Type 1, Pediatric ALL
Intensive Versus Standard One Year Monitoring on Glycaemic Control After Initiating CSII in Children With DT1. DEEP Study
More than half of type 1 diabetes (DT1) children are under CSII (Continuous Subcutaneous Insulin Infusion). Several studies showed that despite a patients' follow-up mostly by hospital-based paediatricians, there are still some…
- Trial name
- DEEP (NCT04100070)
- Testing
- Monitoring of the patients
- Where
- France
- Volunteers
- 320 people
- Sponsor
- ISIS Diabete Service
Diabetes Mellitus, Type I
The Effectiveness of Continuous Glucose Monitoring in Diabetes Treatment for Infants and Young Children
The purpose of this study is to see if the use of a real-time glucose sensor improves diabetes control in young children (less than 4 years old) with Type I diabetes when they are initiated on insulin pump therapy.
- Trial name
- Gerber RTSA (NCT00875290)
- Testing
- Real-time glucose sensor
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Seattle Children's Hospital
Diabetes Mellitus, Type 1
Home Intervention and Social Precariousness in Childhood Diabetes
A pilot study of children whose families are in a precarious situation, who will benefit from a targeted at-home intervention by a pediatric nurse.
- Trial name
- PRECADIAB (NCT04530292)
- Testing
- Intervention by a pediatric nurse at the child's home
- Where
- France
- Volunteers
- 29 people
- Sponsor
- University Hospital, Bordeaux
Diabetes, Diabetes Mellitus, Type 1
Evaluation of Biomarker Expression in Diabetic and Healthy Subjects Over a One Year Period
This study is conducted in the United States of America (USA). The aim of this study is to assess longitudinal variation of immune biomarkers in subjects with type 1 diabetes (T1D), type 2 diabetes (T2D) and healthy, non-diabetic…
- Conditions
- Diabetes, Diabetes Mellitus, Type 1, Diabetes Mellitus, Type 2, Healthy
- Trial name
- NCT01900834
- Testing
- No treatment given
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S