Clinical trials: Validity
Chest X-ray for Clinical Evaluation
Validation of a New Post Image Processing Engine (S-Vue™) for the Reduction of Ionizing Radiation Dose on X-ray Examination in Pediatric Patients
The purpose of this study is to compare X-ray images obtained using the GM85 digital radiography machine at the standard full dose to X-ray images obtained using the GM85 digital radiography machine along with the Samsung S-Vue…
- Trial name
- NCT03935737
- Testing
- Full Dose Chest X-Ray, Low Dose Chest X-Ray
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- The University of Texas Health Science Center, Houston
Chronic Kidney Disease
Uraemic Toxins in Chronic Kidney Disease Paediatric Patients: Interventional Study
Children with chronic kidney disease (CKD) suffer from one of the most devastating diseases in childhood resulting in a lifelong need for health care, and a 3 times decreased life expectancy.
- Trial name
- UToPaed_3 (NCT02634775)
- Testing
- Change in treatment strategy
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- University Hospital, Ghent
Blood Glucose, Executive Function
MOReS Freestyle Libre Validation Study
To measure the effects of interrupting prolonged sitting with brief standing physical activity interventions on physical and cognitive performance, health and wellbeing in young people.
- Conditions
- Blood Glucose, Executive Function, Cognitive Change
- Trial name
- NCT04989712
- Testing
- Exposure
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Oxford Brookes University
Death, Neurodevelopmental Impairment
Apgar-Score in Asphyxiated Infants Under Resuscitation
The specified Apgar-Score in combination with the AAP-Score predicts the morbidity and mortality of asphyxiated newborns.
- Trial name
- NCT01193751
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Technische Universität Dresden
Cystic Fibrosis, Respiratory Infection
Sputum Validation for the Molecular Diagnosis of Respiratory Viral Infections in Cystic Fibrosis
The aim of this pilot study is to demonstrate the feasibility of viral biomolecular diagnosis in sputum compared to nasopharyngeal swab in cystic fibrosis acute respiratory infection.
- Trial name
- EXPIRE (NCT03684759)
- Where
- 3 sites in France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Brest
Pediatric Congenital Heart Surgery
Predictive Value of the FORE-SIGHT™ Monitor for Hemodynamic Deterioration
The postoperative period after congenital heart surgery in children can be a very critical episode, where it is of utmost importance to closely monitor the circulation in these patients.
- Trial name
- NCT01706497
- Testing
- Cerebral tissue oxygen saturation monitoring, blinded
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Autism Spectrum Disorder, Developmental Delay
A Salivary miRNA Diagnostic Test for Autism
The goal of this study is to validate a panel of miRNAs that distinguish children with autism spectrum disorder (ASD) from their non-ASD peers with a positive MCHAT-R.
- Trial name
- NCT02832557
- Testing
- Salivary collection, Vineland Adaptive Behavior Scale-III Assessment, Medical history questionaire
- Where
- United States
- Volunteers
- 998 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
To Determine the Psychometric Properties of the Short Child Occupational Profile
Psychometric / Validation Study
Data for the study will be collected from therapist across the world. The therapists will share data they have already compiled from their caseload.
- Trial name
- NCT01717365
- Where
- United States
- Volunteers
- 499 people
- Sponsor
- Texas Woman's University
Pain, Assessment, Self
Validation of Pain Assessment Scale Faces Thermometer Scale (FTS)
The aim of the study was to psychometrically evaluate the electronic self assessment Faces Pain Scale (FPS). Validation is performed in relation to golden standard of pain scale assessments Faces Pain Scale Reversed (FPS-R) and…
- Conditions
- Pain, Assessment, Self, Child, Only
- Trial name
- NCT05329467
- Testing
- Validation of Faces Thermomether Scale
- Where
- 2 sites in Sweden
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Lund University
Heart Failure
Urdu Translation and Validation of MLHFQ
To translate the Minnesota Living with Heart Failure Questionnaire (MLHFQ) questionnaire into Urdu language of Pakistan. To determine the validity and reliability of cross cultural adapted and Urdu translated MLHFQ questionnaire…
- Trial name
- NCT06076447
- Where
- Pakistan
- Volunteers
- 210 people
- Sponsor
- Riphah International University
Patella Dysplasia
Validity and Reliability of a Danish Version of the Banff Patella Instability Instrument (BPII 2.0-DK)
The Banff Patella Instability Instrument (BPII 2.0) is a disease-specific quality of life questionnaire designed to assess adults with patellar dislocations.
- Trial name
- NCT06257849
- Testing
- BPII 2.0
- Where
- 2 sites in Denmark
- Volunteers
- 65 people
- Sponsor
- Aarhus University Hospital
Bacterial Vaginosis, Urogenital Infection by Trichomonas Vaginalis
A Validation Study of Genzyme Diagnostics OSOM Trichomonas Rapid Test and BVBlue Test
This research is being done to see if two rapid bedside tests (OSOM Trichomonas Rapid Test and BVBlue Test) that give results in 10 minutes are as accurate as standard tests to diagnose common vaginal infections.
- Trial name
- NCT00682851
- Testing
- OSOM Trichomonas Rapid Test, OSOM BVBlue Test
- Where
- United States
- Volunteers
- 519 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Kidney Transplant Rejection, Pathology
Development and Validation of a Comprehensive Classification Automation System for Kidney Allograft Biopsies
Since 1991, the Banff classification has been the gold standard for defining antibody-mediated rejection (AMR) and T-cell mediated rejection (TCMR), thereby guiding the treatment and management of transplant recipients.
- Trial name
- NCT05306795
- Where
- France
- Volunteers
- 4,000 people
- Sponsor
- Paris Translational Research Center for Organ Transplantation
Healthy
3D Ultrasound Validation for Measuring Stomach Volume
The goal is to study the accuracy of 3-dimensional ultrasound (which does not involve radiation) to measure the size of the stomach, comparing it with a previously validated method that involves radiation.
- Trial name
- 3DUSstomach (NCT00588224)
- Testing
- 3D ultrasound
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Surgery
Validation of Numerical Simulation to Predict Proximal Deployment of Standard Stents
Endoprosthesis treatment of aortic pathologies has become the reference in the vast majority of situations. The success of this treatment is conditioned by the choice of the endoprosthesis which must be as adapted as possible to…
- Trial name
- ProxSim (NCT05944835)
- Testing
- Analyzed on the post-operative scanner
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Hospices Civils de Lyon
Cystic Fibrosis, CFTR Gene Mutation
Validation of Therapeutic Efficacy Targeting the Splicing Variants in Cystic Fibrosis and CFTR Pathologies
Cystic Fibrosis, an inherited autosomal recessive disease, arises from mutations in the CFTR gene. For intronic mutations affecting splicing events, oligonucleotides therapy has the potential to restore the production of the full…
- Trial name
- ONB-CFTR (NCT05100823)
- Testing
- Nasal cells sampling, Rectal biopsy sampling
- Where
- France
- Volunteers
- 16 people
- Sponsor
- University Hospital, Montpellier
Cerebral Palsy, Communication
Reliability and Validity of the Dutch Language Version of the CFCS-NL and the VSS-NL in Flanders, Belgium
The study aims to determine the reliability and validity of the CFCS-NL and VSS-NL (both speech and language-related classification scales for children with cerebral palsy) for Flanders so they can be implemented within the…
- Trial name
- NCT04500782
- Testing
- Observation at home.
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Hyperbilirubinemia, Neonatal, Jaundice, Neonatal
Validation of a Jaundice Diagnostic and Monitoring Device for Low-Resource Settings
A team of researchers at Rice University in partnership with clinicians at Queen Elizabeth Central Hospital created BiliSpec, a low-cost battery-powered reader designed to immediately quantify serum bilirubin levels from a small…
- Trial name
- NCT03866213
- Testing
- BiliSpec
- Where
- 3 sites in United States, Malawi
- Volunteers
- 1,000 people
- Sponsor
- William Marsh Rice University
Retinoblastoma
Feasibility of Generating Pluripotent Stem Cells From Patients With Familial Retinoblastoma
The goal of this study is to determine if human RB1-deficient induced pluripotent stem cells (iPSCs) can produce retina, and, furthermore, can give rise to retinoblastoma in culture.
- Trial name
- NCT02193724
- Testing
- Skin Biopsy, Blood Draw
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Jude Children's Research Hospital
Segmentation; Bone
Accuracy of Open-source Software in Semi-automatic 3-Dimensional Reconstruction of the Mandible
Concomitant to the evolution of CBCT devices, several post-processing software packages were developed for producing 3D-printed models of anatomical structures.
- Trial name
- NCT05055986
- Testing
- Semiautomatic segmentation of open-source software
- Where
- Egypt
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cairo University
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