Clinical trials: Validity
Schizophrenia / Schizoaffective Disorder
Validation and Comparative Multi-Omics Benchmarking of Fluid-Derived Volatilomics Biomarkers for the Prevention and Early Detection of Schizophrenia
Schizophrenia (SZ) is one of the most severe and costly mental disorders in terms of human suffering and societal expenditure. Currently, there are no biomarkers that facilitate the early diagnosis of SZ.
- Trial name
- MZvyagintsev (NCT07876089)
- Where
- Germany
- Volunteers
- 3,692 people, healthy volunteers welcome
- Sponsor
- University Hospital, Aachen
Endometriosis
Multicenter Study for Diagnostic Validation of a Laboratory Test for the Diagnosis of Endometriosis
Endometriosis affects at least 1 in 10 women worldwide and is associated with a diagnostic delay of 5-10 years. Currently, definitive diagnosis requires invasive laparoscopy, which is costly and burdensome for patients.
- Trial name
- NCT07553676
- Where
- 8 sites in Austria, Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Diamens FlexCo
Gastric Cancer (GC)
Development and Validation of the Surgical Assessment and Healthcare (SAH) Index for Gastric Cancer Treatment Evaluation
This study develops the Surgical Assessment and Healthcare (SAH) Index, a new tool to fairly evaluate gastric cancer surgery outcomes.
- Trial name
- SAH (NCT07180966)
- Where
- China
- Volunteers
- 780 people
- Sponsor
- Ruijin Hospital
Alzheimer Dementia
Exploratory Study for the Validity of QuQu Scale
Examine the construct validity, the group discriminant ability, and the inter-rater reliability of a novel dementia rating scale (QuQu scale: QUick QUestion scale) candidate for the evaluation of patients with Alzheimer Dementia…
- Trial name
- QuQu (NCT02267486)
- Testing
- Standard therapy of Alzheimer Dementia (AD), Observation
- Where
- Japan
- Volunteers
- 972 people
- Sponsor
- Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan
Psychiatric Disease
Comparing the Impact of Virtual Reality and Paper and Pencil on Psychosocial Rehabilitation
Virtual Reality allows the integration of cognitive rehabilitation in a more ecologically valid context. The purpose of this study is to determine whether this methodology has more impact on psychosocial rehabilitation than a…
- Trial name
- NCT04291586
- Testing
- Virtual reality, Paper and Pencil
- Where
- Portugal
- Volunteers
- 29 people
- Sponsor
- Instituto Irmãs Hospitaleiras Sagrado Coração de Jesus
Tourette Syndrome, Tourette Syndrome in Children
Tourette Discrimination (TD) Stigma Scale
The goal of this qualitative study is to understand the challenges of stigmatization and discrimination in children and young adults with Chronic Tic Disorders (CTD), including Tourette Syndrome.
- Conditions
- Tourette Syndrome, Tourette Syndrome in Children, Tourette Syndrome in Adolescence, Tic Disorder, Childhood
- Trial name
- TD (NCT05696769)
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Wake Forest University Health Sciences
Anemia
Validation of a Smartphone App for Anemia Screening Among General Population
The current standard for anemia screening, complete blood count, presents invasiveness, infrastructure requirements and high costs, leading to serious underestimation of anemia prevalence and insufficient care for anemia…
- Trial name
- NCT05490823
- Testing
- A smartphone app for anemia screening
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Autism Spectrum Disorder, Global Developmental Delay
Reliability and Validity of CCISO for Diagnosis of Autism Spectrum Disorder
The investigators designed the Child-Caregiver Interaction Observation Scale（CCIOS）to assess social communication behaviors, stereotyped behaviors for children with autism spectrum disorder(ASD) via a 20-min video of interactions…
- Conditions
- Autism Spectrum Disorder, Global Developmental Delay, Language Disorder
- Trial name
- NCT04511767
- Testing
- Do not take any interventions
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Children's Hospital of Fudan University
Vision
Does the VTS1000 Infra Red Vein Imager Allow Better Identification of Veins Than Normal Eyesight?
VueTek has developed a head mounted device that will improve the viewing of superficial, subcutaneous vasculature, differentiating it with higher contrast from surrounding tissue.
- Trial name
- VFvalidation (NCT01138228)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Cerebral Palsy
Validity of Bispectral Index Monitoring During Deep Sedation
During Intramuscular botulinum toxin injections for children with cerebral palsy, immobility is essential to inject botulinum toxin to the right muscle.
- Trial name
- NCT02096549
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yeungnam University College of Medicine
Elopement or Escaping of Nursing Home Resident With or Without Dementia
ESCAPE Study : Validation of a Specific Tool Scoring Residents at Risk of Escaping/Elopement From Nursing Homes (ESCAPE)
Residents' escapes occur even if most of the nursing homes (NH) have set up specific devices to prevent from this risk. Therefore, the need to develop and validate a specific tool to assess the risk of escaping was obvious to the…
- Trial name
- ESCAPE (NCT03662464)
- Testing
- No intervention
- Where
- France
- Volunteers
- 4,050 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Spinal Muscular Atrophy
Reliability and Validity of the ACTIVE-mini for Quantifying Movement in Infants With Spinal Muscular Atrophy
The purpose of this study is to investigate the measurement properties of the Ability Captured Through Interactive Video Evaluation-mini (ACTIVE-mini) for quantifying movement in infants with Spinal Muscular Atrophy (SMA).
- Trial name
- NCT03808233
- Testing
- ACTIVE mini
- Volunteers
- 25 people
- Sponsor
- University of Texas Southwestern Medical Center
Hyperemesis Gravidarum
Pregnancy Specific Nausea Questionnaire (PUQE) Translated and Tested in Norwegian
Nausea in early pregnancy (emesis gravidarum) is very common but most often self-limiting. Hyperemesis gravidarum; where nausea and vomiting is severe and protracted is potentially dangerous for the woman and her foetus and…
- Trial name
- PUQE-N (NCT01836835)
- Testing
- Pregnancy Unique Questionnaire of Emesis (PUQE), 24 hours self-reported nutritional intake form
- Where
- 2 sites in Norway
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Dementia, Diagnostic Tests, Routine
SIB-Norwegian Version, Validation and Reliability Study
The purpose of this study is to validate and to test interrater reliability for the Norwgian version of Severe Impairment Battery (SIB).
- Trial name
- NCT00449384
- Testing
- Diagnostic Screening
- Where
- Norway
- Volunteers
- 59 people
- Sponsor
- Sykehuset Innlandet HF
Narcolepsy, Idiopathic Hypersomnia
Spectrometry (MRM) Versus I 125 Radioimmunoassay (RIA) for Quantification of Orexin-A of Patients With Hypersomnolence
In humans, selective loss of orexin neurons is responsible for type 1 narcolepsy (NT1), or narcolepsy with cataplexy, or orexin deficiency syndrome.
- Conditions
- Narcolepsy, Idiopathic Hypersomnia, Cataplexy
- Trial name
- MRM-OREX (NCT05615584)
- Testing
- Quantitative mass spectrometry assay
- Where
- France
- Volunteers
- 117 people
- Sponsor
- University Hospital, Montpellier
Coeliac Disease, Celiac Disease in Children
Validation of the CDAT in the Polish Paediatric Population
The English version of the Celiac Dietary Adherence Test (CDAT) will be translated into Polish using the "forward-backwards-forward" translation model, with the author's consent (already obtained by the applicants).
- Trial name
- CD-PL-CDAT (NCT07142148)
- Testing
- CDAT - phase 1, CDAT - phase 2
- Volunteers
- 20 people
- Sponsor
- Medical University of Warsaw
Thyroid Diseases, Thyroid Neoplasms
Computer Vision-Based Recognition of Parathyroid Glands and Recurrent Laryngeal Nerves in Endoscopic Surgery
This study aims to evaluate the performance of the PTAIR computer vision model for recognizing parathyroid glands and recurrent laryngeal nerves during endoscopic thyroid surgery.
- Trial name
- PTAIR (NCT07628543)
- Testing
- PTAIR Computer Vision Model Assessment
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Fujian Medical University
HIV Infections
HIV Treatment-Readiness Measure (HTRM) Validation
The goal of this study is to assess the reliability of the HIV Treatment Readiness Measure (HTRM) to assist clinicians in: (1) determining whether or not youth living with HIV are ready to initiate HAART and (2) identifying youth…
- Trial name
- NCT00686049
- Where
- 15 sites in United States, Puerto Rico
- Volunteers
- 200 people
- Sponsor
- University of North Carolina, Chapel Hill
Carbapenem-Resistant Enterobacteriaceae
Clinical Validation of the Molecular-Based GenePOC Carba Assay for the Detection and Differentiation of Carbapenemase Genes in Rectal Swab Samples.
The primary purpose of this clinical investigation is to establish the performance of the GenePOC Carba assay on the revogene. This will be achieved by comparing the test to a conventional method for detection of Carbapenemase…
- Trial name
- NCT03680898
- Testing
- Rectal swab collection
- Where
- 3 sites in United States, Canada
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Meridian Bioscience, Inc.
Cervical Cancer
SElf-SAMpling in Cervical Cancer Screening; SESAM Study
Study aims to support development of evidence based health care in Norway through evaluating recently proposed technological improvements in cervical cancer control before their routine use.
- Trial name
- SESAM (NCT02945891)
- Testing
- HPV testing of Evalyn®Brush, FloqSwab and Colli-Pee specimens
- Where
- 4 sites in Norway
- Volunteers
- 310 people
- Sponsor
- Oslo University Hospital
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