Clinical trials: Volume Expansion
Circulatory Failure, Shock State
Fluid-responsiveness Assessment Simplified by Electric Cardiometry in Children
In this study of diagnostic accuracy, the investigators aim to validate a faster, simpler, and noninvasive test of fluid-responsiveness in critically ill children.
- Conditions
- Circulatory Failure, Shock State, Fluid Therapy
- Trial name
- FAST (NCT07522580)
- Testing
- validation a test of fluid-responsiveness in critically ill children
- Where
- 4 sites in France
- Volunteers
- 42 people
- Sponsor
- University Hospital, Bordeaux
Airway Obstruction
Maxillary Expansion Effects in Children With Upper Airway Obstruction
The most frequent causes of mouth breathers are the adenotonsillar hypertrophy. Adenotonsillectomy is the main choice for the elimination of the obstruction.
- Trial name
- NCT03004300
- Testing
- Rapid maxillary expansion, Adenotonsillectomy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Goias
Circulatory Failure / Shock State, Fluid Therapy
Metabolic Fluid Responsiveness in Children
The investigators aim to validate markers of metabolic fluid-responsiveness in children with acute circulatory failure following cardiac surgery.
- Trial name
- METAFRIC (NCT07255469)
- Where
- 8 sites in France
- Volunteers
- 110 people
- Sponsor
- University Hospital, Bordeaux
Hypovolemia, Hemorrhage
Effectiveness of the Pressure Recording Analytical Method in Predicting Fluid Responsiveness in Pediatric Critical Care Patients
The Pressure Recording Analytical Method, invasive hemodynamic monitoring, is an uncalibrated pulse contour analysis, installed in the Mostcare® system that allows a continuous estimation of the stroke volume and thus the cardiac…
- Conditions
- Hypovolemia, Hemorrhage, Fluid Responsiveness
- Trial name
- MOSTCARE-PED (NCT04186416)
- Testing
- Mostcare® device, Transthoracic cardiac ultrasound
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Premature Baby 26 to 32 Weeks, Premature Baby 33 to 36 Weeks
Fluid Responsiveness Evaluation by a Non-invasive Method in Children, Extended to PREterm Infants - FRENCH-PREMA
In this study, the investigators aim to validate a non-invasive marker of fluid-responsiveness in preterm infants (term below 37 gestational week) with acute circulatory failure based on standardized abdominal compression.
- Trial name
- FRENCH-PREMA (NCT06287710)
- Testing
- Non interventional study (study of diagnostic accuracy with an extra echocardiographic assessment).
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Circulatory Failure (Shock)
Fluid-responsiveness in Children Ventilated With LOW Tidal Volume - The FLOW Study.
In this study of diagnostic accuracy, the investigators aim to validate a fluid-responsiveness test in critically ill children mechanically ventilated with low tidal volume.
- Trial name
- FLOW (NCT07494643)
- Testing
- Echocardiographic
- Where
- 6 sites in France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Bordeaux
Blood Volume Expansion
Evaluation of the Venous Excess Ultrasound Score (VExUS) After Circulating Volume Modification in Children.
Venous overload has an impact on peripheral organ perfusion and on the short- and long-term prognosis of intensive care patients. The VExUS ultrasound score is a new tool whose parameters can be used to estimate this impact.
- Trial name
- VExUS-Mod (NCT06695546)
- Testing
- VExUS evaluation ultrasound
- Where
- France
- Volunteers
- 67 people
- Sponsor
- University Hospital, Toulouse
Root Resorption, Orthodontic Appliance
Three-dimensional CBCT Analysis of Root Volume Changes Following Tooth-bone and Bone-borne Maxillary Expansion: A Pilot Study.
External root resorption (ERR) is an undesired side effect observed after rapid maxillary expansion (RME). This study aimed to investigate changes in the root volume of maxillary permanent first molars after RME using tooth-borne…
- Conditions
- Root Resorption, Orthodontic Appliance, CBCT Segmentation
- Trial name
- NCT06912568
- Testing
- Miniscrew insertion, Expander, CBCT
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- University of Roma La Sapienza
Hemolytic-Uremic Syndrome
Shiga Toxin Producing Escherichia Coli (STEC) Volume Expansion
This study will provide feasibility data regarding the conduct of a clinical trail evaluating the use of early aggressive inpatient intravenous rehydration in children with Shiga Toxin producing E. coli infection.
- Trial name
- NCT03275792
- Testing
- D5-0.9%NS, Routine home oral rehydration
- Where
- Canada
- Sponsor
- University of Calgary
Continuous Hemoglobin Measurement
The Accuracy of Noninvasive and Continuous Hemoglobin Measurement by Pulse CO-Oximetry™ in Children Undergoing Volume Expansion
Measuring total hemoglobin(tHb) is a precious step to decide to start or to stop transfusion during operation. The newly developed instrument pulse CO-Cooximetry (Masimo) makes noninvasive monitoring of venous hemoglobin level…
- Trial name
- NCT01364116
- Where
- South Korea
- Volunteers
- 46 people
- Sponsor
- Seoul National University Hospital
Circulatory Failure (Shock)
Fluid Responsiveness Evaluation by a Non-invasive Method in CHildren
In this study, the investigators aim to validate a non-invasive marker of fluid-responsiveness in children with acute circulatory failure based on standardized abdominal compression.
- Trial name
- FRENCH (NCT05919719)
- Testing
- Non interventional study (study of diagnostic accuracy with an extra echocardiographic assessment).
- Where
- France
- Volunteers
- 21 people
- Sponsor
- University Hospital, Bordeaux
Narrow Maxilla
Efficacy of Mini-implant Assisted Maxillary Expansion in Adolescents and Adults
Transverse maxillary deficiency is a common orthodontic issue, affecting around 10% of adults. Late adolescents and adults often require more force to expand the midpalatal suture due to its increased interdigitation.
- Trial name
- MARPE_1 (NCT06449014)
- Testing
- Mini-implants assisted maxillary expansion
- Where
- 2 sites in Belgium
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Erasme University Hospital
Maxillary Transverse Deficiency (MTD)
Effectiveness of Aligners Versus Rapid Maxillary Expansion
Aim of the study is to assess the effectiveness of Invisalign® First clear aligners compared to tooth-borne Hyrax-type maxillary expander on palatal morphology in growing subjects using 3D technology.
- Trial name
- NCT04760535
- Testing
- Invisalign® First Phase I treatment (Align Technology, Inc., Santa Clara, CA, USA), Tooth-borne Hyrax-type maxillary expander
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Turin, Italy