Clinical trials: Water
Choroidal Neovascularization, Choroid Disease
Treatment of Polypoidal Choroidal Vasculopathy in Pachychoroid
This study will evaluate patients with diagnosis of polypoidal choroidal vasculopathy (PCV) in pachychoroid treated with combined therapy, consisting in photodynamic therapy (PDT) and 3 intravitreal therapy (IVT) of Aflibercept…
- Trial name
- NCT04075188
- Testing
- Aflibercept Injection
- Where
- Italy
- Volunteers
- 17 people
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone Palermo
Asphyxia Neonatorum, Morbidity;Newborn
Effects of Probiotic Mixture Supplementation and Evaluation of Intestinal Mucosal Tolerance and Gut Microbiome in Newborns With Perinatal Asphyxia Receiving Hypothermic Treatment
The VISNAT trial is a PILOT STUDY due to absence of previous evidences in literature on using probiotic in newborns with perinatal asphyxia.
- Trial name
- VISNAT (NCT04145713)
- Testing
- Probiotic mixture
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Policlinico Hospital
Pain
Self-administered Intravaginal 2% Lidocaine Gel Prior to Intrauterine Device Insertion in Nulliparous Women
This study is designed to evaluate if self-inserted intravaginal 2% lidocaine gel is effective at decreasing pain during intrauterine device insertion in nulliparous women.
- Trial name
- LIVIIN (NCT01534520)
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Pain
Sucking and Sucrose as Pain Relief for Infants
Sucking and sucrose have been shown to reduce pain during venous puncture in neonates. Our study is designed to see if sucking and sucrose relieve pain during venous puncture in infants age 3-12 months.
- Trial name
- NCT00805623
- Testing
- sucrose
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Rabin Medical Center
Dysentery, Shigella, Shigellosis
Ciprofloxacin Versus Azithromycin for Children Hospitalised With Dysentery
The purpose of this study is to assess the efficacy of 3 days of azithromycin (AZI) compared to 3 days of ciprofloxacin (CIP) (standard-of-care) for the treatment of children hospitalised with dysentery in Ho Chi Minh City.
- Conditions
- Dysentery, Shigella, Shigellosis, Diarrhea
- Trial name
- CIPAZ (NCT03854929)
- Testing
- Ciprofloxacin, Azithromycin
- Where
- Vietnam
- Volunteers
- 364 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Colostomy Site
Comparison of Two Different Solutions for Peristomal Skin Care in Patients With Pediatric Stoma
The aim of this study is to determine the effect of two different skin care solutions used in stoma care on peristomal skin integrity and compare them with each other.
- Trial name
- NCT05686902
- Testing
- CLEANING SOLUTION
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Izmir Katip Celebi University
Venous Vascular Closure, Electrophysiology Study
Mobilization and Outcomes After Venous Closure
The primary objective of this post-market registry is to collect real-world outcomes and evaluate usage practice of MYNX CONTROL™ VENOUS (MCV) Vascular Closure Device (VCD) 6F-12F in sealing femoral venous access sites in…
- Trial name
- MOVE (NCT07246902)
- Testing
- MYNX CONTROLTM VENOUS Vascular Closure Device
- Where
- 9 sites in United States
- Volunteers
- 339 people
- Sponsor
- Cordis US Corp.
Faecal Contamination of Household Drinking Water (Environmental Outcome)
Evaluation of a Project to Distribute Water Filters and Cookstoves in Western Rwanda
DelAgua Health and Development, Manna Energy and the Rwanda Ministry of Health are collaborating on a project financed by carbon credits that will distribute household-based water filters and high-efficiency cook stoves to…
- Trial name
- NCT01882777
- Testing
- Household drinking water filters and cookstoves
- Where
- Rwanda
- Volunteers
- 566 people
- Sponsor
- London School of Hygiene and Tropical Medicine
Low-grade Glioma
Pilot Study of Vinblastine and Tovorafenib in Pediatric Patients With Recurrent/Progressive RAF Altered Low Grade Gliomas
This is a Pilot, multicenter, open-label study of patients less than or equal to 25 years, with recurrent or progressive LGG harboring a CRAF or BRAF alteration, including BRAF V600 mutations and KIAA1549: BRAF fusions.
- Trial name
- VICTORY (NCT06381570)
- Testing
- Tovorafenib, Vinblastine
- Where
- Canada
- Volunteers
- 57 people
- Sponsor
- Daniel Morgenstern
Cognitive Function
Effects of Breakfast on Cognitive Processes in Children
The objective of this study is to test the effects of breakfast on cognitive processing ability in children.
- Trial name
- NCT01063894
- Testing
- breakfast cereal, water
- Where
- United States
- Volunteers
- 291 people, healthy volunteers welcome
- Sponsor
- Kellogg Company
Maxillary Expansion
Rapid Maxillary Expansion Related Oxidative Stress and Periodontal Results
The aim of this study was to investigate the effects of rapid maxillary expansion on local and systemic oxidative stress levels.
- Trial name
- NCT06937775
- Testing
- Periodontal measurements (plaque index, gingival index and probing pocket depth scores ), Biochemical Sample Supply (Collection of serum and saliva samples), Rapid maxillary expansion with Hyrax appliance
- Volunteers
- 35 people
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Bronchiolitis
HFNC Versus NCPAP/ NPPV in Infants With Severe Bronchiolitis
The purpose of the study was to test the null hypothesis that there is no difference between nasal continuous positive airway pressure / nasal positive pressure ventilation (NCPAP/NPPV) and high flow nasal cannula (HFNC) devices…
- Trial name
- NCT04650230
- Testing
- nasal continuous positive airway pressure / nasal positive pressure ventilation (NCPAP/NPPV) and high flow nasal cannula (HFNC) devices
- Volunteers
- 268 people
- Sponsor
- Children's Hospital of Tunis
Retinopathy of Prematurity
Sucrose Analgesia for the Reduction of Pain During Retinopathy of Prematurity Screening
Retinopathy of Prematurity (ROP) screening is one of many potentially painful diagnostic and therapeutic procedures performed routinely on preterm infants in the Neonatal Intensive Care Unit.
- Trial name
- NCT00921544
- Testing
- Sucrose, Sterile water
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- Coombe Women and Infants University Hospital
Autism Spectrum Disorder, Autism
Halliwick Hydrotherapy and Snoezelen
The aim of this study was to evaluate the effectiveness of the Halliwick concept in the adapted Snoezelen multi-sensory environment, in the gross mobility of children belonging to the autism spectrum.
- Conditions
- Autism Spectrum Disorder, Autism, Sensory Disorder
- Trial name
- NCT05134844
- Testing
- Hydrotherapy- Snoezelen, Snoezelen
- Where
- Greece
- Volunteers
- 53 people
- Sponsor
- University of Thessaly
Maxillary Transverse Deficiency (MTD)
Effectiveness of Aligners Versus Rapid Maxillary Expansion
Aim of the study is to assess the effectiveness of Invisalign® First clear aligners compared to tooth-borne Hyrax-type maxillary expander on palatal morphology in growing subjects using 3D technology.
- Trial name
- NCT04760535
- Testing
- Invisalign® First Phase I treatment (Align Technology, Inc., Santa Clara, CA, USA), Tooth-borne Hyrax-type maxillary expander
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Turin, Italy
COVID-19, Children, Only
Water and Land-based Exercise for Children With Post COVID-19 Condition
The latest data indicate that post COVID-19 condition is frequent in children and adolescents, with the most common symptoms being fatigue, shortness of breath, exercise intolerance and weakness.
- Conditions
- COVID-19, Children, Only, Lung Function Decreased, Quality of Life
- Trial name
- postcovidkids (NCT05216549)
- Testing
- Water-based exercise, Land-based exercise
- Where
- Poland
- Volunteers
- 75 people
- Sponsor
- Józef Piłsudski University of Physical Education
Cryotherapy Effect
Cryoprotection of Chemotherapy-induced Oral Mucositis After Autologous Stem Cell Transplantation, a Randomized Study
This study evaluates, among study patients with lymphoma or myeloma undergoing autologous SCT, whether cooling oral mucosa with a cooling device compared with ice cubes/crushed ice or ice pop succeeds in reducing the degree of…
- Trial name
- NCT03203733
- Testing
- Cooral™, cryotherapy
- Where
- 5 sites in Norway, Sweden
- Volunteers
- 182 people
- Sponsor
- Uppsala University
Healthy, Multiple Sclerosis
Normal Chinese Lifespan Brain Charts Initiative (NCLBCI)
Major brain diseases (including neuroimmune diseases, neurodegenerative diseases, and cerebrovascular diseases) are leading causes of death and disability in humans.
- Conditions
- Healthy, Multiple Sclerosis, Neuromyelitis Optica Spectrum Disorders, Neurodegenerative Diseases
- Trial name
- NCT06643858
- Testing
- No intervention
- Where
- China
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Beijing Tiantan Hospital
Dengue Fever, Dengue Hemorrhagic Fever
A Study of Two Doses of WRAIR Dengue Vaccine Administered Six Months Apart to Healthy Adults and Children
The purpose of this study is to evaluate the safety and effectiveness of two different formulations of an investigational dengue vaccine (T-DEN) against a placebo vaccine when two doses are given six months apart to adults and…
- Conditions
- Dengue Fever, Dengue Hemorrhagic Fever, Dengue Shock Syndrome
- Trial name
- NCT00468858
- Testing
- T-DEN-Post-Transfection F17, T-DEN-Post-Transfection F19
- Where
- 11 sites in Puerto Rico
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- U.S. Army Medical Research and Development Command
Cystic Fibrosis
Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis
The investigators will be evaluating bone marrow composition via magnetic resonance imaging in adolescents diagnosed with cystic fibrosis (CF) compared to healthy, matched controls.
- Trial name
- NCT06216704
- Testing
- Magnetic resonance relaxometry, Magnetic resonance spectroscopy, Blood Draw
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
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