Clinical trials: sponsored by Rennes University Hospital
Cerebral Palsy, Hemiparesis; Poststroke/CVA
Characterization of Muscle Activity During a Surface EMG-controlled Rehabilitation Game
The aim of this pilot study is to evaluate muscular activity during a single session of surface electromyography controlled exergame (muscle activation, number of contraction…) in cerebral palsy kids, hemiparetic adults and…
- Conditions
- Cerebral Palsy, Hemiparesis; Poststroke/CVA, Healthy (Controls)
- Trial name
- CONTRACTIV-1S (NCT07838688)
- Testing
- Surface electromyography (sEMG)-controlled rehabilitation game
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Amputation of Lower Extremity, All Causes
Gait and Energy Expenditure in Children With Lower Limb Amputation (MAPEDE)
In lower limb amputation, prosthetic gait has been shown to be particularly energy-intensive. While energy expenditure has been the focus of many studies in adult amputees, this area of research is less developed for paediatric…
- Trial name
- MAPEDE (NCT07076602)
- Testing
- Gait and energy expenditure
- Where
- 8 sites in France
- Volunteers
- 48 people
- Sponsor
- Rennes University Hospital
Sudden Cardiac Arrest, Sudden Cardiac Death
Sudden Cardiac Arrest Related to Sport in Young and Value of the Genetic Assessment: a French Prospective Register
The increased risk of sudden cardiac arrest (SCA) or sudden cardiac death (SCD) related to vigorous physical activity is well-documented.
- Trial name
- RESOUDRE (NCT06642168)
- Testing
- Whole exome sequencing to detect myocardial genetic mutations (SCA group only)
- Where
- 26 sites in France
- Volunteers
- 80 people
- Sponsor
- Rennes University Hospital
Self-management
Self-management Education in Multi-professional Health Centres
The goal of this observational study is to learn about the best educative and organizational dimensions favouring the development of self-management education in multiprofessional health centres.
- Trial name
- ETHOPEE (NCT05950451)
- Testing
- No intervention
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Rennes University Hospital
Interprofessional Education
Impact of IPE in Multidisciplinary Primary Care Centres on Collaborative Competency of Healthcare Students (FLIRT-MSP)
The aim of our study is to evaluate the impact of interprofessional education program (IPEP) for healthcare students in clinical placement in MPCC on interprofessional collaboration (IPC), comparing the acquisition of…
- Trial name
- FLIRT-MSP (NCT06789939)
- Testing
- Train the trainer program for MPCC professionals
- Where
- 26 sites in France
- Volunteers
- 96 people
- Sponsor
- Rennes University Hospital
Infant, Premature
Preliminary Study to the Conception of a Non-invasive Neonatal Monitoring System With Development of a Database
Each year, 300 000 new borns are hospitalised in neonatology units in Europe. This period is very sensitive as newborns are exposed to a high risk of morbidity and mortality, with severe impact on neuro-developmental prognostic.
- Trial name
- Digi-NewB (NCT02863978)
- Testing
- Multimodal signal acquisitions
- Where
- 6 sites in France
- Volunteers
- 746 people
- Sponsor
- Rennes University Hospital
Orthodontic Appliance
Comparison of the Effectiveness of Three Teaching Methods in Oral Hygiene in Adolescent Orthodontic Patients
Orthodontic appliances have been shown to interfere with oral hygiene maneuvers by providing many additional sites for formation and retention of biofilm.
- Trial name
- MAHO (NCT04444154)
- Testing
- Control group, Group with active participation, Group with video and quizz
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Rennes University Hospital
Intensive Care Unit Syndrome
PREMAPIV : Intravesical Pressure Variation at Different Bladder Instillation Volumes in Newborn Children
Abdominal Compartment Syndrome (ASC) is defined by an Intra Abdominal Hypertension (IAH) associated with a new organ failure. The occurrence of this syndrome is not well known in infants.
- Trial name
- NCT01296724
- Testing
- Measure of intravesical pressure
- Where
- France
- Volunteers
- 54 people
- Sponsor
- Rennes University Hospital
Emergencies
Population Pharmacokinetics of Metronidazole in Neonates
The objective of NEOPOPI is to conduct a population pharmacokinetic study of metronidazole in neonates, in order to evaluate and optimize neonatal dose regimen.
- Trial name
- METROPOP (NCT04031183)
- Where
- 7 sites in France
- Volunteers
- 171 people
- Sponsor
- Rennes University Hospital
ARDS Related to Severe Acute Respiratory Syndrome-Coronavirus (SARS-CoV) 2, Acute Refractory Heart Failure Related to SARS-CoV 2
Extracorporeal Membrane Oxygenation (ECMO) and Coronavirus Disease (COVID) 19
The role of ECMO in the treatment of patients with severe COVID-19 (Acute Respiratory Distress Syndrome (ARDS) and/or acute refractory heart failure) is not yet known.
- Trial name
- ECMO-SARS (NCT04397588)
- Where
- 44 sites in France
- Volunteers
- 761 people
- Sponsor
- Rennes University Hospital
Premature
Gut Bacteria and Brain of the Baby
The project is a prospective French population based cohort. A hundred moderate preterms born at GA30-326/7 will be enrolled for a longitudinal follow-up up to 2 years of corrected age.
- Trial name
- BaBBa (NCT04432636)
- Testing
- Data collection of environmental factors, Collection of maternal feces, Collection of infant feces
- Where
- France
- Volunteers
- 94 people
- Sponsor
- Rennes University Hospital
Malnutrition, Child
The "Self Evaluation of Food Intake" (SEFI) as a Screening Test for Hospital Malnutrition in Children Over 10 Years
The goal is to find a simple tool that can be used by medical and paramedical staff and that is reliable to identify children at risk for malnutrition.
- Trial name
- SEFI (NCT04536974)
- Testing
- SEFI tool
- Where
- 6 sites in France
- Volunteers
- 368 people
- Sponsor
- Rennes University Hospital
Apnea of Prematurity
Apnea Treatment in Premature Infants Using an Automatic Vibro-tactile Stimulator Triggered by the Detection of Apnea-bradycardia.
The goal of the SENSITACT system is to activate an adaptive kinesthetic stimulation to treat apnea-bradycardia events on preterm infants, while minimizing deleterious effects, in particular arousals that can be due either to…
- Trial name
- SENSITACT (NCT03651648)
- Testing
- SENSITACT System
- Where
- France
- Volunteers
- 14 people
- Sponsor
- Rennes University Hospital
Epilepsy, Healthy Subjects
Mindfulness Meditation for Epilepsy
In one-third of epileptic patients treated in France, seizures persist despite drug treatment. These so-called "refractory" epilepsies are among the most severe.
- Trial name
- MIME (NCT04687904)
- Testing
- Mindfulness meditation training, Therapeutic education
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Leukemia, Lymphoblastic, Acute, Pediatric
Childhood B-acute Lymphoblastic Leukaemia and Role of CD9 Gene Regulation in Relapse
B-acute lymphoblastic leukaemia (B-ALL) is the most common cancer in children, with 20% of patients relapsing. CD9, a transmembrane protein, is linked to the migratory and adhesion capacities of leukaemia cells and could be…
- Trial name
- REALL CD9 (NCT06649253)
- Testing
- Sampling bone tissue and blood
- Where
- 3 sites in France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Spina Bifida
Evaluation of muLtimodal and Non-invasive SPINa Bifida Neurovessels During Prospective Follow-up
The aim of the study is to investigate known urinary biomarkers in order to determine whether they can be predictive of a risk of damage to the upper urinary tract and therefore the kidneys in patients with spina bifida.
- Trial name
- SPINLESS (NCT06041334)
- Testing
- Collection of a urine sample, Magnetic Resonance Imaging of the bladder
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Rennes University Hospital
Post Traumatic Stress Disorder
Efficacy of Traumatic Memory Modification Using Memory Reconsolidation and Propranolol Among Adolescents With PTSD
The aim of this study is to demonstrate the effectiveness of propranolol in blocking reconsolidation by reducing PTSD symptoms in the short and long term in adolescents with PTSD for more than 3 months.
- Trial name
- PROPRADO (NCT04921982)
- Testing
- Propranolol
- Where
- 10 sites in France
- Sponsor
- Rennes University Hospital
Peripheral Artery Disease
Exercise Testing in Peripheral Artery Disease Patients
The aim of this study was to evaluate exercise testing in case of patients suspected of Peripheral Artery Disease (PAD).
- Trial name
- ExercisePAD (NCT03186391)
- Testing
- Data collected
- Where
- France
- Volunteers
- 5,000 people
- Sponsor
- Rennes University Hospital
Childhood Cancer, Nausea with Vomiting Chemotherapy-Induced
Predict CHimio-or Radiation-induced NAusea and Vomiting in Children/adolescents Treated for Cancer
Chemo- or radiation-induced nausea and vomiting (CRVN) is one of the most frequent and feared side effects. It is a symptom that is few or not at all evaluated.
- Trial name
- PaNACHE (NCT06869005)
- Testing
- BARF scale
- Where
- 5 sites in France
- Volunteers
- 150 people
- Sponsor
- Rennes University Hospital
Childhood Autism
Melatonin Dose-effect Relation in Childhood Autism
Melatonin is a neurohormone produced from serotonin which promotes sleep. The alterations in central and peripheral serotonin neurobiology and in circadian sleep-wake rhythms observed in autistic disorder suggest abnormalities in…
- Trial name
- MELADOSE (NCT01780883)
- Testing
- melatonin
- Where
- 4 sites in France
- Volunteers
- 34 people
- Sponsor
- Rennes University Hospital