Clinical trials: AI
Dementia
Human-LLM Conversations as a Digital Signature of Cognitive Performance in Adults
Subtle changes in language are among the early signs of cognitive decline in Alzheimer's disease and related conditions. Researchers are therefore studying whether language can help identify cognitive changes earlier and at…
- Trial name
- HLC-CogMark (NCT07890207)
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Technion, Israel Institute of Technology
Students of Undergraduate School of Nursing
Promoting Students' Development of Ultimate Concern Care Strategies
Teaching intervention
- Trial name
- NCT07532616
- Testing
- Teaching
- Where
- Taiwan
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Preclinical Dental Education
AI-Generated Versus Human Feedback in Preclinical Restorative Dentistry
This study aims to compare the effects of artificial intelligence-generated feedback and human instructor feedback on learning outcomes in preclinical restorative dentistry education.
- Trial name
- AIF-HF (NCT07682116)
- Testing
- Artificial Intelligence-Generated Feedback, Human Instructor Feedback
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Seda Nur Karakaş
Exercise Training, Exercise Behavior
Adaptive Self-Efficacy-Based AI Coaching for Cycling
The primary objective of this study is to evaluate whether adaptive, AI-delivered personalized self-efficacy-based AI coaching based on real-time physiological and performance feedback enhance indoor cycling power output during a…
- Conditions
- Exercise Training, Exercise Behavior, Exercise Adherence Challenges, Motivation for Physical Activity
- Trial name
- AI (NCT07318233)
- Testing
- Group 1: Self-efficacy-based AI coaching, Group 2: Static AI Affirmations
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cervical Cytology, PAP
Techcyte SureView Cervical Cytology System Clinical Validation Study
The clinical study is a multi-center, retrospective, blinded, matched-pair, two-arm clinical study in which one test assessment and a control assessment of liquid-based cytology (LBC) pap tests are performed and compared to a…
- Trial name
- NCT06767111
- Testing
- Digital cervical cytology slide imaging system with artificial intelligence (AI) algorithm in vitro diagnostic (IVD) device
- Where
- United States
- Volunteers
- 4,596 people, healthy volunteers welcome
- Sponsor
- Techcyte, Inc.
Ambient AI System, Emergency Department
Evaluation of a Generative AI-Based Voice Documentation System for Patient-Clinician Communication in the Emergency Department and Its Impact on Clinical Workflow Efficiency and Usability
This research study at Samsung Medical Center evaluates the impact of Ambient AI system, a Generative AI-based communication and documentation system developed by NAVER, on the efficiency and quality of medical record-keeping…
- Conditions
- Ambient AI System, Emergency Department, Generative ai
- Trial name
- CLOVA Charty (NCT07637591)
- Testing
- VoiceEMR
- Where
- South Korea
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Deep Vein Thrombosis, Superficial Thrombophlebitis
DOACT Algorithm Versus AI-Based Decision Models in Oral Anticoagulant Therapy for Vascular Patients
Study using a decision algorithm for the application of an oral anticoagulant calculator in vascular diseases, aimed at validating a clinical decision-support tool for conditions such as deep vein thrombosis, superficial…
- Conditions
- Deep Vein Thrombosis, Superficial Thrombophlebitis, Pulmonary Thromboembolisms, Clinical Decision Support Systems
- Trial name
- DOACT (NCT07290608)
- Testing
- DOACT algorithm, No algorithm, LLM-based tools
- Where
- Brazil
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- ITALO EUGENIO SOUZA GADELHA DE ABREU
Colo-rectal Cancer, Cancer Colon
AI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening Test
Freenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early.
- Conditions
- Colo-rectal Cancer, Cancer Colon, Cancer, Rectum, Neoplasms,Colorectal
- Trial name
- NCT03688906
- Where
- 30 sites in United States, Canada
- Volunteers
- 3,275 people, healthy volunteers welcome
- Sponsor
- Freenome Holdings Inc.
Mental Disease
AI-Powered Mental Health Screening in University Students
The goal of this observational study is to test an artificial intelligence (AI) tool that can help screen for mental health risks .
- Trial name
- NCT07092085
- Testing
- AI model
- Where
- China
- Volunteers
- 17,386 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Chest X-ray for Clinical Evaluation
X-ray Assisted Diagnostic System
X-ray examination is one of the most commonly used imaging modalities, especially chest X-ray, which is routinely performed for hospitalized patients.
- Trial name
- NCT07497243
- Testing
- AI-assisted radiologist diagnostic group, Radiologist diagnostic group
- Where
- 4 sites in China
- Volunteers
- 16,000 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Therapeutic Alliance, Empathy
AI Ambient Scribe in Psychiatry
The goal of this clinical trial is to learn if an artificial intelligence (AI) tool that listens to appointments and drafts clinical notes can help clinicians in psychiatric care.
- Conditions
- Therapeutic Alliance, Empathy, Documentation, Artificial Intelligence (AI)
- Trial name
- AASP (NCT07777224)
- Testing
- Artificial Intelligence Ambient Scribe
- Where
- 8 sites in Switzerland
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Psychiatrie St. Gallen
Mental Health Issue
Using an Online Psychotherapy Program and AI-assisted Interventions for Postsecondary Student Mental Health
The prevalence of mental health challenges and disorders in post-secondary students, demands accessible and efficacious care. Online psychotherapy and psychoeducation programs have shown significant effectiveness in mitigating…
- Trial name
- NCT05754723
- Testing
- e-Psychotherapy/Psychoeducation
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Dr. Nazanin Alavi
Colorectal Cancer (CRC) Screening
A Novel Multi-functional Artificial Intelligence System on Treatment Efficacy and Implementation in Colonoscopy
To overcome non-neoplastic polyp (NNP) resections, computer-aided diagnosis (CADx) systems have been developed. In a meta-analysis, the performance of CADx systems was superior to endoscopists.
- Trial name
- mAInstream (NCT07844252)
- Testing
- CADe/CADx
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Healthy Longevity
A Randomized Controlled Trial of a Multi-domain Smartphone Intervention Incorporating Generative AI for Healthy Older Adults
This study evaluates the efficacy of a smartphone-based multi-domain intervention designed to promote healthy aging and prevent cognitive decline in older adults.
- Trial name
- NCT07524478
- Testing
- Multidomain intervention, Control
- Where
- Japan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tatsuhiro Hisatsune
COVID19
Evaluation of the AudibleHealth Dx AI/ML-Based Dx SaMD Using FCV-SDS in the Diagnosis of COVID-19 Illness
The AudibleHealth Dx is a diagnostic software as a medical device (Dx SaMD) consisting of an ensemble of software subroutines that interacts with a proprietary database of Signal Data Signatures (SDS), using Artificial…
- Trial name
- NCT05175690
- Testing
- Diagnostic Software as Medical Device
- Where
- United States
- Volunteers
- 1,126 people, healthy volunteers welcome
- Sponsor
- AudibleHealth AI, Inc.
Skin Lesion
Correlation of Dermatologist Made Biopsy Decision With AI Assisted Total Body Photography Detection of Outlier Lesions
This research study will determine how a smart phone application (app) for total body photography outlier analysis compares to a dermatologist's decision to biopsy skin lesions.
- Trial name
- NCT05940090
- Testing
- SkinIO
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Halcyon Dermatology
MACE, Atrial Fibrillation (AF)
throMboembolic Risk Associated To High atrIal Fibrillation riSk
Cardiovascular diseases are the leading cause of mortality from treatable conditions in the European Union and the second from preventable causes, with a standardized mortality rate of 257.8 deaths per 100,000 inhabitants.
- Conditions
- MACE, Atrial Fibrillation (AF), Quality-adjusted Life-years, Electronic Health Records
- Trial name
- MATHIAS (NCT07441759)
- Testing
- AI_MATHIAS
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Lung Cancer
AI-Assisted Chest CT Interpretation Across the Lung Cancer Care Continuum
This investigator-initiated, single-center study consists of a retrospective artificial intelligence model-development stage and a prospective physician reader-study stage.
- Trial name
- NCT07829640
- Testing
- Chest CT Artificial Intelligence Decision-Support System
- Where
- China
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Hospital-acquired Infections
AI-Driven Prediction of Hospital-Acquired Infections With EHR
This is a multi-center, clinical study designed to evaluate the application and effectiveness of an AI-assisted predictive model for identifying and diagnosing infection, leveraging multimodal health data.
- Trial name
- NCT06791382
- Testing
- AI-Based Diagnostic and Prognostic Model
- Where
- 2 sites in China
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- The Eye Hospital of Wenzhou Medical University
Covid19
Evaluation of a COVID-19 Pneumonia CXR AI Detection Algorithm
This study investigates the diagnostic performance of an AI algorithm in the detection of COVID-19 pneumonia on chest radiographs.
- Trial name
- NCT04561024
- Testing
- AI model
- Where
- Hong Kong
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Ensemble Group Holdings, LLC