Clinical trials: ARTHROPLASTY, REPLACEMENT; ANESTHESIA
Arthroplasties, Knee Replacement, Nerve Block
Post-Operative Urinary Retention on Revision Knee Arthroplasty: the Role of Intrathecal Morphine
Revision total knee arthroplasty (rTKA) is a frequently performed procedure. Adequate pain management is an important feature, especially for fast-track and Enhanced Recovery After Surgery (ERAS) programs.
- Conditions
- Arthroplasties, Knee Replacement, Nerve Block, Urinary Retention Postoperative, Anesthesia, Spinal
- Trial name
- POURRKA (NCT07050277)
- Testing
- Intrathecal Morphine, No Intrathecal Morphine
- Where
- Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Arthroplasty, Replacement, Knee, Anesthesia, Conduction
Femoral Triangle Block: Early Mobilization and Postoperative Analgesia After Total Knee Arthroplasty
The objective of this trial is to compare the efficacy of three different nerve blocks as an analgesic option after total knee arthroplasty (TKA), based on muscle strength, mobilization and pain.
- Conditions
- Arthroplasty, Replacement, Knee, Anesthesia, Conduction, Pain, Postoperative, Ultrasonography, Interventional
- Trial name
- NCT03518450
- Testing
- Apex Femoral Triangle Block, Femoral Nerve Block, Adductor Canal Block
- Where
- Spain
- Volunteers
- 78 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Anesthesia, Conduction, Arthroplasty, Replacement, Knee
Concentration Effect of Local Anesthetics on Femoral Nerve Block Efficiency
US-guided femoral nerve block is used effectively in post-operative pain management in the surgical treatment of the lower extremity.
- Conditions
- Anesthesia, Conduction, Arthroplasty, Replacement, Knee, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- NCT03623230
- Testing
- Ultrasound Guided Femoral Nerve Block, Dressing, Bupivacaine 0.25% Injectable Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people
- Sponsor
- Bozyaka Training and Research Hospital
Hypotension After Spinal Anesthesia
Carotid Ultrasound for Post-Spinal Anesthesia Hypotension in Elderly Hip Surgery
This study aims to evaluate the predictability of preoperative carotid artery-corrected flow time (CFTc) for hypotension after spinal anesthesia in patients undergoing geriatric hip replacement surgery.
- Trial name
- NCT07876063
- Testing
- Ultrasound
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Tanta University
Knee Arthropathy, Anesthesia, Local
Modified TIPS Block for Total Knee Arthroplasty
The is carried out to compare triple injection peri-sartorial block to a modified block including an extra local anesthetic injection deep to the adductor longs muscle via a medial to lateral approach regarding the peri-operative…
- Trial name
- NCT06539910
- Testing
- General Anesthesia, TIPS block, Modified TIPS block
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Alexandria University
Anesthesia, Spinal, Arthroplasty, Replacement, Knee
Mepivacaine vs. Bupivacaine Spinal Anesthetic in Total Knee Arthroplasty
The purpose of this study is to determine if a shorter-acting spinal anesthetic called mepivacaine has advantages over a longer-acting medication called bupivacaine.
- Conditions
- Anesthesia, Spinal, Arthroplasty, Replacement, Knee, Pain Management, Early Ambulation
- Trial name
- NCT02980926
- Testing
- Mepivacaine, Bupivacaine
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Arthroplasty Replacement, Knee, Anesthesia Conduction
Migration Rate for Continuous Adductor Canal Block Catheters After Primary Total Knee Arthroplasty Surgery: a Comparison Between Two Insertion Techniques
Continuous adductor canal block (CACB) is becoming increasingly popular for providing postoperative analgesia following knee arthroplasties.
- Trial name
- ISAFExOOPS (NCT07681622)
- Testing
- ISAFE technique for adductor canal catheter insertion, OOPS technique
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Arthroplasty, Replacement, Knee, Chronic Pain Post-Proceduraal
The Effect of Regional Anaesthesia and Genetic Factors in the Development of Chronic Pain Following Total Knee Arthroplasty
The study aims to assess the effect of spinal anaesthesia against a general anaesthesia with a femoral block, with respect to the incidence of chronic pain following a total knee replacement.
- Trial name
- NCT04206046
- Testing
- Spinal anaesthesia, General anaesthesia
- Where
- Malta
- Volunteers
- 200 people
- Sponsor
- Sciberras, Stephen M.D.
Anesthesia
Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service
A comparison of two anesthetic techniques for total knee replacements: (1) Peri-Articular Injection (PAI), local infiltration between the popliteal artery and capsule of the knee block (IPACK) and single-shot adductor canal block…
- Trial name
- EKAT-TeleTPS (NCT03747146)
- Testing
- Continuous Adductor Canal Catheter (ACC)
- Where
- United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Total Knee Arthroplasty
Saphenous Nerve Block Versus Femoral Nerve Block for Total Knee Arthroplasty
Currently, the regional anesthetic standard of care for total knee replacement surgery is combined spinal/epidural, with or without a femoral nerve block, or FNB.
- Trial name
- NCT01333943
- Testing
- Study Group: Experimental, Control Group
- Where
- United States
- Volunteers
- 94 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthritis, Musculoskeletal Disease
Use of Corticosteroid in Intraopertive Injections in Total Knee Replacement Surgery.
The goal of this clinical trial is to find out which type of steroid medicine, when added to a standard pain-control injection during total knee replacement surgery, works best at reducing pain, limiting opioid use, and improving…
- Conditions
- Knee Osteoarthritis, Musculoskeletal Disease, Surgery
- Trial name
- TKACSI (NCT07151417)
- Testing
- PAI, PAI + steroid, PAI + zilretta
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Walter Reed National Military Medical Center
Hip Replacement Surgery, Hip Replacement, Total
OPPOSED (anteriOr hiP arthroPlasty regiOnal aneSthEsia stuDy) Study
Main indications for total hip arthroplasty (THA) are degenerative osteoarthritis of the coxofemoral joint, osteonecrosis of the hip, congenital disorders such as dysplasia and inflammatory arthritis.
- Conditions
- Hip Replacement Surgery, Hip Replacement, Total, Hip Pain, Hip Arthroplasty
- Trial name
- NCT07017192
- Testing
- SIFI Block, ESP block
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Post Operative Pain, Anesthesia
Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties
Comparison of post-operative pain after total shoulder surgery. The Principle Investigator will be comparing Exparel single shot block to Interscalene catheter
- Conditions
- Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
- Trial name
- NCT05868330
- Testing
- Interscalene Catheter, Exparel Single Shot Interscalene Block
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Melinda Seering
Knee Arthropathy
Persistent Post Surgical Pain After Total Knee Arthroplasty
Patients undergone total knee replacement are randomized to receive a "fast track" regional anesthesia protocol or a "traditional" regional anesthesia continuous infusion by both a femoral and sciatic catheter to assess if this…
- Trial name
- NCT06182059
- Testing
- continuous peripheral nerve block
- Where
- Italy
- Volunteers
- 436 people
- Sponsor
- Policlinico di Monza SpA
Hip Fractures, Arthroplasty, Replacement, Hip
PENG Block + LIA For Endoprosthesis Surgery
The goal of this clinical trial is to learn if a new local anesthesia technique can control pain as well as the standard spinal anesthesia for adults having hip endoprosthesis surgery.
- Conditions
- Hip Fractures, Arthroplasty, Replacement, Hip, Pain, Postoperative, Anesthesia and Analgesia
- Trial name
- PENG 360° (NCT07239817)
- Testing
- Pericapsular Nerve Group Blocks with Local Infiltration Analgesia, spinal anesthesia
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- ASST Gaetano Pini-CTO
Arthroplasty, Replacement, Knee
Postoperative Complications Following Total Knee Arthroplasty
The aim of this study is to investigate the effect of combined spinoepidural and general anesthesia on the incidence of postoperative complications following total knee arthroplasty
- Trial name
- NCT03746444
- Testing
- General Anesthesia, Regional Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Ufuk University
Opioid Consumption, Postoperative, Pain, Postoperative
Comparison of Pain Relief Methods for Hip Surgery: A Study on Two Different Nerve Block Techniques
This prospective randomized comparative study aims to compare the analgesic efficacy of pericapsular nerve group block (PENG) and lumbar erector spinae plane block (L-ESP) groups to relieve postoperative pain in participants over…
- Conditions
- Opioid Consumption, Postoperative, Pain, Postoperative, Nerve Block, PENG Block
- Trial name
- NCT06821516
- Testing
- Evaluation of the postoperative analgesic effectiveness of PENG block in participants undergoing total hip arthroplasty under spinal anesthesia, Evaluation of the postoperative analgesic effectiveness of lumbar erector spinae block in participants undergoing total hip arthroplasty under spinal anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Knee Osteoarthritis, Arthritis Knee
How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Total Knee Arthroplasty? A Feasibility Study.
The use of periarticular injection and adductor canal block are well-established techniques used both in combination or in isolation in the management of postoperative pain for patients undergoing total knee arthroplasty.
- Conditions
- Knee Osteoarthritis, Arthritis Knee, Knee Disease, Opioid Use
- Trial name
- TRUE KnORTH (NCT04648072)
- Testing
- Adductor Canal Block, Periarticular Injection
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Health Sciences North Research Institute
Joint Replacement Surgery
Reversal of Spinal Anesthesia Residual Motor Block Via Intrathecal Catheter
The purpose of this study is to determine the feasibility of administering a predetermined amount of normal saline into the intrathecal or subarachnoid space via a small spinal catheter to reduce or eliminate the effects of…
- Trial name
- IT-Cath (NCT07404982)
- Testing
- Normal Saline 10 mL Injection
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Beth Israel Deaconess Medical Center
Perioperative Analgesia, Hip Replacement, Total
Pericapsular Nerve Group Block Versus Intrathecal Morphine for Analgesia After Total Hip Arthroplasty
The Pericapsular Nerve Group (PENG) block is an effective method for postoperative pain management in patients undergoing primary total hip arthroplasty (THA) via a posterolateral approach.
- Conditions
- Perioperative Analgesia, Hip Replacement, Total, Postoperative Pain, Hip Disease
- Trial name
- NCT07449585
- Testing
- PNEG block, Spinal anesthesia with opioid, Spinal anesthesia without opioid
- Volunteers
- 180 people
- Sponsor
- Medical University of Gdansk