Clinical trials: Abdominal Obesity Metabolic Syndrome
Insulin Resistance, Obesity
Surgical Removal of Visceral Fat Tissue (Omentectomy) Associated to Bariatric Surgery: Effects on Insulin Sensitivity
The intraabdominal fat is associated with insulin resistance, a condition that is in the basis of diabetes, metabolic syndrome and some cardiovascular diseases.
- Conditions
- Insulin Resistance, Obesity, Metabolic Syndrome X
- Trial name
- NCT00545805
- Testing
- Roux-en-Y Gastric Bypass plus total omentectomy, Roux-en-Y Gastric Bypass
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- University of Campinas, Brazil
Abdominal Obesity Metabolic Syndrome
Effects of Green-MED Diet Via the Gut-fat-brain Axis
Mediterranean (MED) diet, richer in plants/seeds (and dietary polyphenols) and low in processed meat (green-MED diet) may have a pronounced beneficial effect on age-related declines that begin in middle age, reflected by changes…
- Trial name
- DIRECT-PLUS (NCT03020186)
- Testing
- Physical activity, Physical activity+ MED diet, Physical activity+green MED diet
- Where
- Israel
- Volunteers
- 294 people, healthy volunteers welcome
- Sponsor
- Ben-Gurion University of the Negev
Abdominal Obesity-Metabolic Syndrome
Effect of a Meal Replacement on Weight Loss Obesity Patients With Metabolic Syndrome
The purpose of this study is to determine whether meal replacement, SlimWell ®, is effective in the treatment of obesity patients with metabolic syndrome.
- Trial name
- SlimWell (NCT02626741)
- Testing
- meal replacement group, control group
- Where
- Thailand
- Volunteers
- 138 people
- Sponsor
- Mahidol University
Obesity, Abdominal, Anesthesia Morbidity
CPAP in Patients With Severe Obesity After Anesthesia
The goal of this study is to compare two continuous positive airway pressure (CPAP) settings on heart and lung function in patients with severe obesity after anesthesia. The main questions it aims to answer are: 1.
- Conditions
- Obesity, Abdominal, Anesthesia Morbidity, Apnea, Obstructive Sleep, Atelectases, Postoperative Pulmonary
- Trial name
- NCT06287632
- Testing
- Recruitment/ITP-CPAP (Intervention A), Standard CPAP (Intervention B), Atmospheric Pressure
- Volunteers
- 60 people
- Sponsor
- Massachusetts General Hospital
Weight Loss, Metabolic Syndrome
Use of Continuous Glucose Monitoring in Non-Diabetic Population to Compliment Signos Mobile Health Platform
Metabolic syndrome and resulting downstream health effects remains a growing health concern. In published trials, the use of continuous glucose monitoring (CGM) assists behavioral changes efforts, leading to improved adherence…
- Conditions
- Weight Loss, Metabolic Syndrome, Pre-diabetes, Central Obesity
- Trial name
- NCT05121844
- Testing
- Continuous Glucose Monitor Device
- Where
- United States
- Volunteers
- 31,187 people, healthy volunteers welcome
- Sponsor
- Signos Inc
Weight Loss, Metabolic Syndrome
Signos DM2 Empowerment Study (SIGNOS-CGM-EMPOWER-201-2022)
The use of continuous glucose monitoring (CGM) in earlier data has inspired behavioral changes leading to improved adherence to an exercise plan in individuals and eating habits in people with diabetes.
- Conditions
- Weight Loss, Metabolic Syndrome, Diabetes Mellitus, Type 2, Central Obesity
- Trial name
- NCT05874635
- Testing
- Continuous Glucose Monitor Device
- Where
- United States
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- Signos Inc
Metabolic Syndrome
P20 Extending Sleep to Reverse Metabolic Syndrome
This pilot study will test the acceptability and feasibility of a sleep extension intervention in community-dwelling, short-sleeping, racially/ethnically diverse middle-aged adults with MetS.
- Trial name
- NCT03596983
- Testing
- Sleep Intervention, Week 2 Intervention
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- NYU Langone Health
Obesity, Insulin Resistance
Weight Loss and Abdominal Fat Responses to Different Diet Compositions
The purpose of this study is to assess the effectiveness of two different reduced calorie diets that have different combinations of carbohydrate, fat, and protein content in 2 groups of study participants: insulin sensitive…
- Conditions
- Obesity, Insulin Resistance, Metabolic Syndrome
- Trial name
- NCT01034046
- Testing
- Low Carbohydrate Diet, Low Fat Diet
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Nevada, Las Vegas
Metabolic Syndrome
Dose Ranging Study of the Effects of Alpha Lipoic Acid on Oxidative Stress
Heart disease is the most common cause of death in the United States and it is commonly found in people with diabetes and high cholesterol.
- Trial name
- Alpha (NCT00857376)
- Volunteers
- 77 people
- Sponsor
- Johns Hopkins University
Metabolic Syndrome, Metabolic Syndrome Obesity
Impact of Medical Nutrition Therapy and Follow-Up Frequency on Metabolic Syndrome Parameters
There is no study that has investigated the effects of medical nutrition therapy and more frequent follow-up via telehealth on metabolic syndrome parameters in patients with MetS who have multiple metabolic disorders such as…
- Conditions
- Metabolic Syndrome, Metabolic Syndrome Obesity, Metabolic Syndrome Parameters
- Trial name
- NCT06813131
- Testing
- Dietary counseling, calling via telephone
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Hacettepe University
Overweight and Obesity, Men
High-Intensity Interval Training and Fat Mass Losses
The aims of this study was to compare two isoenergetic HIIT (High-intensity Interval training) programs (cycling vs. running) on body composition, substrate oxidation at rest and during a moderate exercise, muscle functionality…
- Trial name
- RIESLING (NCT05311800)
- Testing
- Physical activity
- Where
- France
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Laboratoire des Adaptations Métaboliques à l'Exercice en conditions Physiologiques et Pathologiques
Overweight , Obesity, Abdominal Obesity-Metabolic Syndrome
Body Weight Reduction and Metabolic/Biochemical Parameters in Overweight or Obesity
This was a single-center prospective observational cohort study conducted in Poland in the context of routine metabolic outpatient care.
- Trial name
- NCT07645105
- Testing
- Routine Lifestyle-Based Weight Reduction Management
- Where
- 2 sites in Poland
- Volunteers
- 53 people
- Sponsor
- Medical University of Silesia
Metabolic Syndrome X
Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial
The purpose of this study is to determine whether telmisartan and/or a low-glycemic index diet are effective in reducing intra-myocellular lipid (muscle fat) content.
- Trial name
- NCT00147264
- Testing
- Low-Glycemic Index Diet vs. Control Diet
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- McMaster University
Iron Deficiency,, Anaemia,
Nutritional Transition in the Maghreb and Prevention of Obesity and Non-communicable Diseases
Problematic and state of the art Obesity and its associated non communicable diseases (NCDs) are rising rapidly in middle income countries, such as those in the Maghreb (North Africa).
- Conditions
- Iron Deficiency,, Anaemia,, Overweight,, Metabolic Syndrome
- Trial name
- Obe-Maghreb (NCT01844349)
- Where
- 2 sites in Morocco, Tunisia
- Volunteers
- 8,218 people
- Sponsor
- Agnes GARTNER
Metabolic Syndrome
Impact of Exercise Training Intensity on Abdominal Visceral Fat and Risk Factors Associated With the Metabolic Syndrome
The purpose of this study is to determine if sixteen weeks of high intensity physical training is more effective than sixteen weeks of low intensity physical training in reducing abdominal fat and lowering risk factors associated…
- Trial name
- NCT00350064
- Testing
- Exercise Training
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Morbid Obesity, Metabolic Syndrome
Changes in Different Fat Compartments and Their Effect on Particular Manifestations of Metabolic Syndrome After Bariatric Procedures.
The metabolic risks associated with obesity are closely correlated with central (abdominal), rather than a peripheral (gluteofemoral) fat pattern It has been shown that weight loss after bariatric surgery is followed by metabolic…
- Conditions
- Morbid Obesity, Metabolic Syndrome, Visceral Obesity
- Trial name
- NCT00431587
- Where
- Israel
- Volunteers
- 1,000 people
- Sponsor
- Hadassah Medical Organization
Metabolic Syndrome, Insulin Resistance
Asprosin and miRNA Expression in Young Women With Metabolic Syndrome
Metabolic syndrome is a major risk factor for cardiovascular disease and type 2 diabetes, and its prevalence in young adults is increasing. Early identification of individuals at risk may improve prevention strategies.
- Conditions
- Metabolic Syndrome, Insulin Resistance, Obesity, Abdominal, Dyslipidemias
- Trial name
- ASPRO-MetS (NCT07917364)
- Testing
- Biomarker panel (asprosin, microRNA, BDNF, cortisol), Clinical and questionnaire assessment
- Where
- Poland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Applied Sciences in Nowy Targ
Metabolic Syndrome, Abdominal Obesity
Copenhagen Obesity Risk Assessment Study
The aim of the present study is to assess the effect of a high intake of industrially produced trans fatty acids for 16 weeks on abdominal obesity and risk markers of type 2 diabetes and heart disease in healthy, moderately…
- Conditions
- Metabolic Syndrome, Abdominal Obesity, Heart Disease, Type 2 Diabetes
- Trial name
- COBRA (NCT00655902)
- Testing
- Trans fat (soy bean oil), Control fat (sunflower oil)
- Where
- Denmark
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Obesity, Stress
Brain-Gut Interactions in Overweight and Normal Weight Patients With Chronic Abdominal Pain
About 15 to 20 percent of individuals living in the United States have chronic abdominal pain, often of unknown origin, which is often difficult to diagnose and treat.
- Conditions
- Obesity, Stress, Irritable Bowel Syndrome, Women
- Trial name
- NCT00824941
- Where
- United States
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- National Institute of Nursing Research (NINR)
Abdominal Obesity Metabolic Syndrome, Subjects With Poor Fitness Status
A Health Promotion Project for Workers at National Taiwan University Hospital
Background and Purpose: Fitness is the foundation for health and quality of life for individuals. Recent changes in lifestyle and eating habit in Taiwan have significantly increased the prevalence of metabolic syndrome that may…
- Trial name
- NCT02001376
- Testing
- Intensive exercise, Home exercise, Control group live as usual
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital