Clinical trials: Ablation Techniques, RFA
Knee Osteoarthritis
Parallel Versus Perpendicular Technique for Genicular Radiofrequency
Although there are different ways of performing genicular nerve radiofrequency on knee pain, to our knowledge, there is no stuies comparing the clinical outcomes of a parallel technique vs. a perpendicular technique.
- Trial name
- NCT05528965
- Testing
- Perpendicular Group, Parallel Group
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Hepatocellular Carcinoma, Liver Metastases
Clinical Intervention Modelling, Planning and Proof for Ablation Cancer Treatment
The main objective of the project is to bring the existing radio frequency ablation (RFA) model for liver cancer treatment (Project IMPPACT, Grant No. 223877, completed in February 2012) into clinical practice.
- Trial name
- ClinicIMPPACT (NCT02745600)
- Testing
- RFA therapy simulator
- Where
- 4 sites in Austria, Finland and 2 more
- Volunteers
- 60 people
- Sponsor
- University of Leipzig
Cardiac Arrhythmia
Use of "iSuite" During CMR-guided Electrophysiological Procedures
The perpuse of this study is to investigate the feasibility of the Philips interventional MRI suite "iSuite" to create an electroanatomical map of the heart based on which the real-time location of the catheters can be correctly…
- Trial name
- NCT04727645
- Testing
- Philips interventional MRI suite (Philips Healthcare, Best, the Netherlands)
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Ziekenhuis Maastricht
Low Back Pain
Effect of the Temperature Used in Thermal Radiofrequency Ablation
This study will determine if lumbar facets medial branches RFA at 90 degrees Celsius provides more overall pain relief (i.e., percent of improvement), when compared to ablation at 80 degrees Celsius with no additional adverse…
- Trial name
- NCT02148003
- Testing
- RFA at 90 degrees Celsius, RFA at 80 degrees Celsius, C-arm guided 20-gauge radiofrequency needle
- Where
- United States
- Volunteers
- 199 people
- Sponsor
- The Cleveland Clinic
Radiofrequency Ablation in Patients With Spinal Hardware
Safety of Spine Radiofrequency Procedures
The goal of the study was to determine if patients undergoing radiofrequency neurotomy (RFN) of lumbar facet joints that are adjacent to previously placed pedicle screws from a fusion, would lead to an increase in the temperature…
- Trial name
- NCT02210052
- Testing
- Radiofrequency cannula
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Atrial Fibrillation
A Prospective Multi Centre Trial on Bipolar Radiofrequency Ablation of Atrial Fibrillation
The study is a prospective multi-centre study to investigate the effect of a new bipolar ablation strategy of the left atrium in patients with paroxysmal or permanent atrial fibrillation over time.
- Trial name
- NCT00184249
- Testing
- Bipolar radiofrequency ablation
- Sponsor
- Norwegian University of Science and Technology
Hepatocellular Carcinoma, Chemoembolization, Therapeutic
TACE+RFA Versus TACE Alone for Intermediate-stage Hepatocellular Carcinoma
The current standard treatment for intermediate-stage HCC (BCLC stage B) is transcatheter arterial chemoembolization (TACE) alone. The combination of TACE with RFA has also reported to be an effective treatment for HCC.
- Conditions
- Hepatocellular Carcinoma, Chemoembolization, Therapeutic, Ablation Techniques, RFA
- Trial name
- TORCH (NCT02435953)
- Testing
- TACE, RFA
- Where
- China
- Volunteers
- 241 people
- Sponsor
- Ming Zhao
Hepatocellular Carcinoma, Radiofrequency Ablation
Radiofrequency Ablation Using Octopus Electrodes for Small Hepatocellular Carcinoma With No-touch Technique
The aim of this study is to evaluate clinical outcome of RFA for small single nodular HCC using no touch technique with separable clustered electrode (Octopus) in a prospective multicenter manner Participating center: Seoul…
- Trial name
- NCT03375281
- Testing
- RFA
- Where
- 5 sites in South Korea
- Volunteers
- 140 people
- Sponsor
- Seoul National University Hospital
Carcinoma, Hepatocellular, Cirrhosis
Expansion of Conventional Criteria for Liver Transplantation in Hepatocellular Carcinoma Through Downstaging
This clinical trial is aimed at extending the chance of liver transplantation, through downstaging procedures, to patients with hepatocellular carcinoma (HCC) exceeding conventional Milan Criteria.
- Trial name
- NCT01387503
- Testing
- Liver transplantation
- Where
- 10 sites in Italy
- Volunteers
- 74 people
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Low Back Pain
Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies
The purpose of this study is to document the effectiveness of the Nimbus Multi-tined Expandable Electrode (MEE) Probe in carrying out the heating and ablation (cutting) of the small medial branch nerves that carry pain…
- Trial name
- NCT02120625
- Testing
- Lumbar MB RFN
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Nimbus Concepts, LLC
Carcinoma, Hepatocellular
RFA for Small HCC With No-touch Technique Using Octopus Electrode
In this study, the investigators are going to prospectively compare the clinical outcomes (technical success rate, 12 month local tumor progression rate, complication rate, tumor seeding rate) of Radiofrequency ablation (RFA)…
- Trial name
- NCT02832882
- Testing
- No-touch RFA, Conventional tumor puncture RFA
- Volunteers
- 118 people
- Sponsor
- Seoul National University Hospital
Carcinoma, Hepatocellular
RFA for Small HCC With No-touch Technique and Dual Cooled-Wet Electrode
The purpose of this study is to prospectively compare the clinical outcomes (local tumor progression rate, technical success rate, complication rate) of no touch radiofrequency ablation (RFA) technique for Hepatocellular…
- Trial name
- NCT02806076
- Testing
- No-touch RFA arm, Conventional tumor puncture RFA arm
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Liver Cancer (Primary and Metastatic), Lung Cancer (Diagnosis)
Registry of Minimally Invasive Cancer Treatment Using Spectral Angio-CT Image Guidance
This study collects data from patients undergoing minimally invasive, image-guided cancer treatments at participating hospitals in the Netherlands and France.
- Conditions
- Liver Cancer (Primary and Metastatic), Lung Cancer (Diagnosis), Bone Cancer Metastatic, Bone Cancer Tumor
- Trial name
- PreciseOnco (NCT07636148)
- Where
- 3 sites in France, Netherlands
- Volunteers
- 2,000 people
- Sponsor
- Mark C Burgmans, MD PhD
Paroxysmal Atrial Fibrillation
Assessment of Reconstruction and Inverse Reconstruction in Right Atrium by Multimodal Echocardiographic Techniques
The purpose of the study is to assess the reconstruction and inverse reconstruction in right atrium by speckle tracking echocardiography combined with real-time three dimensional echocardiography for atrial fibrillation patients…
- Trial name
- NCT02838914
- Testing
- radiofrequency ablation (RFCA)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Atrial Fibrillation
Hybrid Staged Operating Room and Interventional Catheter Ablation for Atrial Fibrillation
Prospective, multi-center, investigator-driven trial. This study hypothesizes that combining surgical endoscopic and transcatheter techniques in a staged fashion provides superior clinical outcomes than isolated surgical/EP…
- Trial name
- HISTORIC-AF (NCT01622907)
- Where
- 10 sites in France, Germany and 3 more
- Volunteers
- 100 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
We Evaluated CT-guided Localization of the Right Phrenic Nerve to Enhance Safety in Transcatheter Ablation
Right Phrenic Nerve Localization on CT for Ablation
The anatomical location of the right phrenic nerve (RPN) in close proximity to the right pulmonary veins has become a critical consideration for electrophysiologists performing pulmonary vein isolation, the cornerstone treatment…
- Trial name
- NCT07330791
- Where
- Spain
- Volunteers
- 80 people
- Sponsor
- Centro Medico Teknon
Sacroiliac; Backache, Chronic Pain
Palisade Lateral Branch Technique Using Multi-tined Needles for Sacro-iliac Joint Radiofrequency Ablation
The sacro-iliac joint is a large joint that can be the source of chronic pain. Many treatment options have been proposed to treat SIJ pain, with variable efficacy.
- Trial name
- TriPal (NCT05043961)
- Testing
- Palisade sacroiliac joint radiofrequency ablation using 3-tined needles
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Menstrual Bleeding, Heavy
NovaSure Study: Endometrial Ablation in Women With Heavy Menstrual Bleeding
Heavy menstrual bleeding (HMB) affects 30% of women worldwide. It negatively influences physical activity, work productivity, sexual life and overall quality of life.
- Trial name
- RAMBOS (NCT05856838)
- Testing
- NovaSure ablation
- Where
- Belgium
- Volunteers
- 30 people
- Sponsor
- University Hospital, Ghent
Barrett's Esophagus, High-grade Dysplasia in Barrett Esophagus
Eradicating Barrett's Esophagus Using Radiofrequency Ablation or a Novel Hybrid Argon Plasma Coagulation Technique
Lay summary: Barrett's Esophagus (BE) involves a change of the esophagus lining (BE epithelium) which in a small proportion of patients could be the starting point for the development of cancer (esophageal adenocarcinoma).
- Conditions
- Barrett's Esophagus, High-grade Dysplasia in Barrett Esophagus, Low Grade Dysplasia in Barrett Esophagus
- Trial name
- BURN (NCT03621319)
- Testing
- Hybrid argon plasma ablation (HAPC), Radiofrequency ablation (RFA)
- Where
- 13 sites in United States
- Volunteers
- 41 people
- Sponsor
- Erbe Elektromedizin GmbH
Osteoarthritis Knee, Chronic Pain
Comparison of Denervation Techniques for the Treatment of Knee Osteoarthritis: Continuous Ablative Radiofrequency Vs. Chemical Denervation with Absolute Alcohol
This randomized clinical trial compares two minimally invasive treatments for knee osteoarthritis pain that has not responded to conventional therapies.
- Trial name
- NCT06858228
- Testing
- Continuous Ablative Radiofrequency, Chemical Denervation with Absolute Alcohol
- Where
- Brazil
- Volunteers
- 288 people
- Sponsor
- Federal University of São Paulo