Clinical trials: Abortions, Spontaneous, Habitual
Abortion, Recurrent
Platelet Indices and Recurrent Pregnancy Loss
The aim of this study was to evaluate relationship between platelet indices, red blood cell indices and recurrent pregnancy loss.
- Trial name
- NCT05190796
- Testing
- platelet indices
- Where
- Egypt
- Volunteers
- 150 people
- Sponsor
- Menoufia University
Mannose-Binding Lectin Deficiency, Recurrent Pregnancy Loss
Association Between Plasma Level of Mannose Binding Lectin and Human Reproduction
A low plasma level of mannose binding lectin (p-MBL) is associated with unexplained recurrent pregnancy loss (RPL), but it is not investigated if it is associated with unexplained reproductive failure in general, including…
- Conditions
- Mannose-Binding Lectin Deficiency, Recurrent Pregnancy Loss, Recurrent Implantation Failure, Infertility
- Trial name
- NCT05169541
- Where
- Denmark
- Volunteers
- 500 people
- Sponsor
- Aalborg University Hospital
Cervical Insufficiency
Relation of the Area of Cerclage With Preterm Birth
This study is planned prospectively in pregnancies who applied to Etlik Zübeyde Hanım Women's Health Care, Training and Research Hospital which is a teritiary hospital with 15.000 births anually, between January 2022 and January…
- Trial name
- NCT05220839
- Testing
- Type of cerclage procedure Mc Donald
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Preterm Labour, Cervical Insufficiency
Intramuscular vs Rectal Progesterone in Preventing Preterm Labour After Cervical Cerclage
Preterm labour is a major cause of neonatal morbidity and mortality worldwide. Progesterone supplementation is known to help reduce the risk of preterm birth in high-risk women.
- Conditions
- Preterm Labour, Cervical Insufficiency, Pregnancy, High-Risk
- Trial name
- PROCER (NCT07307092)
- Testing
- Intramuscular Progesterone, Rectal Progesterone
- Where
- Pakistan
- Volunteers
- 820 people
- Sponsor
- Hina Mukhtar
Cervical Incompetence
Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC)
The investigator aimed to compare the effect of anesthesia on overall postoperative outcomes including post-operative pain score and the fetal well-being (heart rate) in patients undergoing transabdominal cervico isthmic…
- Trial name
- NCT03636048
- Testing
- Bupivacaine Hcl 0.5% Inj, Propofol 10 milligram/ML
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Recurrent Miscarriage
Intralipid Related Effect on NKcells in Patients With Unexplained Recurrent Spontaneous Abortion
Evaluating the effect of intralipid on the natural killer cells
- Trial name
- NCT03132779
- Testing
- Intralipid
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Ahmed Mohamed Bahaa Eldin Ahmed
Recurrent Miscarriage
Walking and Dietary Modification for Recurrent Early Miscarriages
This study is part of a big one aiming to evaluate how lifestyle interventions during pregnancy affect obstetric results, neonatal metabolism and the intelligence of the offspring (study not yet completed).
- Trial name
- W&D (NCT03023137)
- Testing
- Walking & dietary modification
- Where
- Brazil
- Volunteers
- 480 people
- Sponsor
- Hospital dos Servidores do Estado do Rio de Janeiro
Inflammatory Response, Abortion, Habitual
Explore the Role of NLRP7 in the Regulation of Progestereone Induced Decidualization of Human Endometrial Stroma Cells
The investigators have found that NLRP7 was upregulated and nuclear translocated in an in vitro model of decidualization. Knock-down or overexpression of NLRP7 reduced or enhanced the expression of decidual marker IGFBP-1.
- Trial name
- NCT04148638
- Where
- Taiwan
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Infertility, Female, Abortion, Habitual
Effects of PGS in Infertile Female Patients With RPL
Recurrent pregnancy loss (RPL) is a multifactorial disorder which affects about 1% of all couples and challenges both patients and clinicians technically and emotionally.
- Trial name
- NCT02223221
- Testing
- IVF/ICSI, PGS, Without PGS
- Where
- China
- Volunteers
- 189 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Miscarriage, Recurrent, Abortion, Habitual
Intravenous Immunoglobulin (IVIG) for Treatment of Unexplained Secondary Recurrent Miscarriage
Recurrent miscarriage is a prevalent reproductive problem that affects many couples who are trying to establish a family. This clinical study will evaluate the effectiveness of intravenous immunoglobulin (IVIG) in improving the…
- Trial name
- NCT00606905
- Testing
- Gamimune N or Gamunex 10%, normal saline
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Chicago
Cervical Insufficiency, Cervical Stiffness
Cervical Stiffness Assessment in High-risk Pregnancies for Preterm Birth
Cervical length is usually measured using ultrasound, and if it is shortened, hormone therapy (progesterone) is recommended to reduce the risk of premature birth.
- Trial name
- PilotProPre (NCT07541313)
- Where
- Switzerland
- Volunteers
- 21 people
- Sponsor
- Luzerner Kantonsspital
Recurrent Pregnancy Losses, Positive Anti Phospholipid Syndrome
Preconceptional Thromboprophylaxis in Recurrent PREGNANCY LOSSES Caused by Antiphospholipid Syndrome
Preconceptional use of low molecular weight heparin (enoxaparin) and aspirin in patient with recurrent miscarriages with positive anti phospholipid antibodies increase the implantation rate and the duration of pregnancy with low…
- Trial name
- NCT01661439
- Testing
- low molecular weight heparin (enoxeparine)
- Where
- Egypt
- Volunteers
- 316 people, healthy volunteers welcome
- Sponsor
- Woman's Health University Hospital, Egypt
Miscarriage, Recurrent, Infertility
The Role of NLRP Gene Family (NLRP1~14) in Recurrent Miscarriage and Infertility
Development of mole was not associated with segregation of mutated NLRP7 allele in the haploid oocyte. We hypothesize NLRP7 is a maternal factor involved in regulating early embryo development or embryo-uterine interaction.
- Trial name
- NCT04141618
- Where
- Taiwan
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- National Cheng-Kung University Hospital
Infertility, Abnormal Uterine and Vaginal Bleeding, Unspecified
Optimum Misoprostol Dose Prior to Office Hysteroscopy
Misoprostol is an effective agent for cervical priming before office hysteroscopy, vaginal route is the best, optimum dose not yet known.
- Conditions
- Infertility, Abnormal Uterine and Vaginal Bleeding, Unspecified, Recurrent Abortion
- Trial name
- NCT01612065
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Cairo University
Abortion, Habitual
RECAB-ASA; Treatment of Recurrent Abortion With Aspirin
The aim of this study is to examine whether treatment with 75 mg aspirin daily compared with placebo could reduce the risk for a new miscarriage.
- Trial name
- RECAB-ASA (NCT02823743)
- Testing
- Aspirin
- Volunteers
- 400 people
- Sponsor
- Göteborg University
Luteal Phase, Biomarkers
Early Pregnancy Cohort and Preimplantation Factor
Miscarriage is a common event associated with severe psychological and social morbidity, further tormenting in women suffering recurrent pregnancy loss (RPL) by at least three consecutive losses.
- Conditions
- Luteal Phase, Biomarkers, Abortion, Spontaneous, Abortion, Habitual
- Trial name
- PEP-cohort (NCT02761772)
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2
Cerclage for Twins With Short Cervix
A prospective randomized control trial that will compare cervical cerclage plus vaginal progesterone to vaginal progesterone along in twin pregnancies complicate by a short cervix (</= 15.0mm) between 16w0d to 25w6d.
- Conditions
- Preterm Birth, Preterm Labor With Preterm Delivery, Unspecified Trimester, Fetus 2, Cervical Incompetence, Cervical Shortening
- Trial name
- NCT03077633
- Testing
- Cervical Cerclage placement, Vaginal Progesterone
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pediatrix
Preterm Labor, Cervical Incompetence
Cervical Cerclage for Singleton Pregnant on Vaginal Progesterone With Progressive Cervical Length Shortening
The aim of this study is to Determine whether cerclage with vaginal progesterone will: 1. Reduce the overall spontaneous preterm birth rate. 2. Prolong pregnancy latency. 3. Improve neonatal outcome.
- Trial name
- NCT03837288
- Testing
- Cerclage
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Habitual Abortion
CXCL9 and CXCL11 Levels in Patients With Autoimmune Thyroiditis and Habitual Abortions
The purpose of this study is to measure serum CXCL9 and CXCL11 levels in patients with autoimmune thyroiditis and habitual abortions
- Trial name
- NCT01644318
- Where
- Turkey (Türkiye)
- Sponsor
- Ankara Education and Research Hospital
Preterm Birth, Cervical Insufficiency
Bed Rest With a Short Cervix on Preterm Birth
Maternal AR has long been used to prevent PTB. However, definitions of AR vary widely, ranging from complete bed rest to partial limitation of physical activity for one or more hours daily.
- Conditions
- Preterm Birth, Cervical Insufficiency, Bed Rest, Pregnancy Complications
- Trial name
- BEWISE (NCT07577388)
- Testing
- Activity Restriction, No Activity Restriction
- Volunteers
- 6,000 people
- Sponsor
- Julie Glavind