Clinical trials: Absorption; Iron
Iron Deficiency (Without Anemia)
Absorption of Iron From Stabilized Lactoferrin: A Study in Women With Iron Deficiency
Lactoferrin (LF) is a natural iron-binding protein found in milk. It exists either in an iron-free state (apo-LF) or bound to iron (holo-LF).
- Trial name
- LOBSTER (NCT07394972)
- Testing
- FeSO4 + meal-matrix, FeSO4 + native LF + meal-matrix, FeSO4 + NaCas-LF + meal-matrix
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Nicole Stoffel
Iron-deficiency, Ferritin Threshold
Defining the Serum Ferritin Concentration in Kenyan Women at Which the Body Senses Iron Depletion and Begins to Upregulate Iron Absorption
The serum or plasma ferritin concentration (referred to hereafter as ferritin) is the most widely used indicator to detect iron deficiency and a low ferritin indicates depleted iron stores.
- Conditions
- Iron-deficiency, Ferritin Threshold, Iron Absorption, Stable Iron Isotopes
- Trial name
- NCT05266703
- Testing
- Isotopically labelled iron sulfate 15mg
- Where
- Kenya
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Absorption
The Effects of Acute Erythropoietin on Hepcidin and Dietary Iron Absorption Following Military-relevant Exercise in Energy Deficit: Pilot Study
Military personnel frequently experience declines in iron status during training and when in the field, which may compromise performance.
- Trial name
- IRON BOOST (NCT07517562)
- Testing
- Exercise test
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Adiposity, Iron-deficiency
Central and Peripheral Adiposity and Iron Absorption
Adiposity is a state of sub-clinical inflammation, thus hepcidin is increased in adiposity, often leading to iron deficiency in this population group.
- Trial name
- NCT03642223
- Testing
- Stable iron isotopes
- Where
- Lebanon
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Absorption, Iron Deficiencies
Maximizing the Benefits of Iron in Ready-to-Use Therapeutic Foods for Malnourished Children in Kenya
Reports from the Kenya Red Cross Society (KRCS) in Kwale County, southern Kenya, indicate a limited impact of Ready-to-Use Therapeutic Foods (RUTFs) on malnutrition or anemia.
- Conditions
- Iron Absorption, Iron Deficiencies, Severly Acutely Malnourished Children, Malnutrition in Children
- Trial name
- SAMI (NCT07315295)
- Testing
- Iron absorption from RUTF on Day 0, Treatment with RUTF for 80 days, Iron absorption from RUTF on Day 20
- Where
- 2 sites in Kenya, Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- ETH Zurich
Iron Absorption
Iron Long-Term Labelling Study Malawi
Conventional indirect indicators of iron status, using serum and red blood cell biomarkers, are confounded by inflammation from common infections in sub-Saharan Africa, a region with a high prevalence of iron deficiency, making…
- Trial name
- NCT02977806
- Where
- Malawi
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Prof. Michael B. Zimmermann
Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption
A Study to Investigate the Effect of Vitamin D3 Supplementation on Iron Status in Iron Deficient Women
Iron is one of the most vital elements in humans as it plays a role in physiological functions such as transferring and storing oxygen, transporting electrons and catalysing numerous reactions, from oxidative metabolism to…
- Conditions
- Iron Deficiency, Anemia; Deficiency, Nutritional, With Poor Iron Absorption, Vitamin D Deficiency
- Trial name
- NCT02714361
- Testing
- Vitamin D3 supplement
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Chester
Iron Absorption
Iron Absorption in Vegetarian Children
Few areas are more controversial in pediatric nutrition than the role of a vegetarian diet for children. Advocates make strong health claims whereas others have expressed safety concerns, especially regarding iron nutrition.
- Trial name
- NCT01489007
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Anemia
Evaluation of Natureheme-iron on Iron Absorption Effect and Anti-oxidation Functions
Iron deficiency problem has always been in Taiwan. This is a randomized, double-blind trial. Subjects separate to 3 groups, one group (n = 20) take two Natureheme-iron capsules a day for a total of 12 weeks, another group (n =…
- Trial name
- NCT02871128
- Testing
- Natureheme-iron, supplement
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Chung Shan Medical University
Infant, Dietary Supplements
Iron Absorption From Infant Formula and Iron Drops in Infants (MJAU-studien)
Iron deficiency (ID) affects up to 25% of Swedish infants and severe ID is associated with cognitive and behavioral problems. To avoid this, iron supplements or iron-fortified infant foods are recommended for infants.
- Conditions
- Infant, Dietary Supplements, Food, Fortified
- Trial name
- MJAU (NCT01216709)
- Testing
- ferrous sulfate, iron-fortified infant formula (12.4 mg iron/L), iron-fortified infant formula (2.3 mg iron/L)
- Where
- Sweden
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Umeå University
Vitamin A Deficiency
Impact of Consumption of Orange-fleshed Sweet Potatoes on the Vitamin A Status of Bangladeshi Women of Reproductive Age
The primary purpose of this study is to determine whether daily consumption of orange-fleshed sweet potatoes increases the vitamin A status of Bangladeshi women of reproductive age.
- Trial name
- NCT00453648
- Testing
- White-fleshed sweet potatoes, Orange-fleshed sweet potatoes (boiled), Orange-fleshed sweet potatoes (fried)
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Iron Bioavailability
Assessment of Iron Absorption From Aspergillus Oryzae
The objective of this study was to compare the absorption of a new iron product, iron enriched Aspergillus oryzae to ferrous sulfate in humans using a double stable-isotope technique.
- Trial name
- NCT03156725
- Testing
- Ferrous Sulfate, Aspiron
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Iowa State University
Evaluation of Bioavailability of Supplemental Forms of Iron
Glycoprotein Matrix-Bound Iron Improves Iron Absorption
A double-blind, randomized crossover study was conducted that evaluated absorption kinetics of 3 forms of dietary supplement iron by measuring iron levels in the blood after acute ingestion.
- Trial name
- NCT06738199
- Testing
- dietary iron supplementation
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Mary Hardin-Baylor
Iron-deficiency
Iron Absorption From Iron Fortified Extruded Rice Co-fortified With Various Solubilizing Agents
Food fortification is regarded as a safe and cost-effective approach to counteract and prevent iron deficiency. Rice is a staple food for millions of people living in regions where iron-deficiency anaemia is a significant public…
- Trial name
- NCT03703739
- Testing
- Reference meal 1, Reference 2, Test meal A
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron-deficiency
Iron Absorption From Fortified Extruded Rice Using Different Extruding Temperatures.
Food fortification is regarded as a safe and cost-effective approach to counteract and prevent iron deficiency. Rice is a staple food for millions of people living in regions where iron-deficiency anaemia is a significant public…
- Trial name
- NCT03703726
- Testing
- Reference meal, Test meal A, Test meal B
- Where
- Switzerland
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Deficiency
Mineral Absorption From Fortified Rice Produced With Different Fortification Techniques
The investigators studies will compare iron, respectively iron and zinc bioavailability from fortified rice produced from different fortification techniques using stable isotopic labels.
- Trial name
- NCT02572128
- Testing
- Fortified rice
- Where
- 2 sites in Switzerland
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Anemia, Iron Deficiency
Effect of Timing of Micronutrient Powder Consumption on Iron Absorption in Infants
Infants and young children in sub-Saharan Africa have high rates of iron deficiency anemia (IDA), which adversely affects their growth and cognitive development.
- Trial name
- NCT02989311
- Testing
- Fortified maize porridge (MNP and Iron), Fortified Maize porridge (MNP + Iron + GOS)
- Where
- Kenya
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Absorption, Bariatric Surgery
Iron Absorption Trial
Introduction: There are indications that the absorption of oral iron supplementation is reduced after a Roux- en -Y gastric bypass.
- Conditions
- Iron Absorption, Bariatric Surgery, Roux- en -y Gastric Bypass
- Trial name
- NCT02228902
- Testing
- Ferrous fumarate, Ferrous gluconate
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rijnstate Hospital
Thalassemia, Iron Overload
Inhibitory Effect of a Polyphenol Supplement on Dietary Iron Absorption in Adults with Thalassemia
Genetic disorders, such as thalassemia, can lead to iron overload and severe adverse health outcomes. In iron-loading thalassemia, iron overload is due to increased iron absorption.
- Trial name
- NCT05326503
- Testing
- Meal matrix with polyphenol supplement (PPS), No meal matrix with PPS
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Iron Absorption
Iron Bioavailability of Fortified Oat Drink
This study will follow a double blinded randomized controlled study design to enroll 20 apparently healthy 6 year old children. The children will be fed with two different nutrient fortified oat drinks labeled with stable…
- Trial name
- NCT01423162
- Testing
- Dietary Intervention (with Vit C then without Vit C), Dietary Intervention (without Vit C followed by with Vit C)
- Where
- Philippines
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- PepsiCo Global R&D