Clinical trials: Acquired Platelet Function Disorder
Glioma, Coagulopathy
Hemostasis Alterations in Neurosurgical Patients
Prospective, observational study aimed to investigate the specific hemostatic alterations in patients undergoing glial tumor resection.
- Conditions
- Glioma, Coagulopathy, Acquired Platelet Function Disorder, Thromboelastometry
- Trial name
- ABCD (NCT02652897)
- Testing
- Exposure to glioma resection surgery, Exposure to colon resection surgery
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Santiago R. Leal-Noval
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
The Coordination of Rare Diseases at Sanford (CoRDS) is an international patient registry that serves as a centralized resource for rare disease research.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- United States
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Cardiovascular Diseases, Platelet Aggregation, Spontaneous
Platelet Function on Abacavir and Tenofovir
This is a small observational study aimed at observing differences in platelet function in HIV patients on abacavir versus tenofovir based anti-HIV drugs.
- Conditions
- Cardiovascular Diseases, Platelet Aggregation, Spontaneous, HIV/AIDS
- Trial name
- NCT03081572
- Testing
- Platelet aggregation
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of California, Los Angeles
Acquired Platelet Function Disorder
Influence of Extracorporeal Circulation on Platelet Function of Patients Undergoing Cardiac Surgery
This study is planned to investigate the relationship between duration of extracorporeal circulation and the extent of (acquired) platelet dysfunctions in patients undergoing cardiac surgery.
- Trial name
- NCT01354847
- Testing
- Multiple electrode aggregometry analyses (Multiple Electrode Aggregometry, Multiplate(R), Verum Diagnostica, Munich, Germany)
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Goethe University
Human Immunodeficiency Virus
Platelets Study: Influence of the Antiretroviral Treatment on the Platelet Physiology During HIV Infection
HIV infection is associated with an immune activation and an inflammatory response - despite an active antiretroviral therapy - which may lead notably but not exclusively to cardiovascular diseases.
- Trial name
- PLAQUETTE (NCT02532348)
- Testing
- Blood samples
- Where
- France
- Volunteers
- 133 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Acquired Platelet Function Disorder
Platelet Function With New Pediatric Oxygenator and Heparin and Non Heparin Coating in Pediatric Cardiac Surgery
Optimal anticoagulation is mandatory during CPB in order to avoid hemostatic system activation. Platelet dysfunction is commonly observed after procedures performed under cardiopulmonary bypass (CPB).
- Trial name
- NCT01648712
- Testing
- Balance surface, Carmeda heparin-coated surface, non -heparin extracorporeal pediatric device for operation
- Where
- France
- Volunteers
- 48 people
- Sponsor
- Hôpital Necker-Enfants Malades
Von Willebrand Diseases
Frequency of Hemorrhages Associated With the Functional Anomalies of Willebrand Factor in Emergency Patients
ECMO has improved the outcome of heart or respiratory failure and carcinogenic shock and are increasingly used. However bleeding complications occurring in up to 50% of patients are poorly understood and worsen the overall…
- Trial name
- WITECMO-H (NCT03070912)
- Where
- 7 sites in France
- Volunteers
- 257 people
- Sponsor
- University Hospital, Lille
Perioperative Bleeding, Coagulopathy During Cardiac Surgery
Flow-Based Platelet Function Assessment Using Total Thrombus-Formation Analysis System (T-TAS) and Early Bleeding After Cardiac Surgery With Cardiopulmonary Bypass (CPB)
The goal of this observational study is to learn how flow-based platelet function measured with the Total Thrombus-formation Analysis System (T-TAS) relates to early postoperative bleeding in adults undergoing cardiac surgery…
- Conditions
- Perioperative Bleeding, Coagulopathy During Cardiac Surgery, Platelet Dysfunction, Cardiac Surgery
- Trial name
- TTAS-CPB (NCT07619261)
- Testing
- Total Thrombus-formation Analysis System (T-TAS)
- Volunteers
- 30 people
- Sponsor
- Hospital de la Santa creu i Sant Pau - Barcelona