Clinical trials: Active tDCS
Spinal Cord Injury Cervical
Active tDCS Versus Sham tDCS for Upper Limb Recovery in Incomplete Tetraplegic Patients
Spinal Cord Injury (SCI) at the cervical level results in motor and sensory impairment below the lesion level and may determine a consistent loss of the use of the upper limbs, with a substantial impact on daily life activities.
- Trial name
- NCT05390853
- Testing
- Active tDCS
- Where
- Italy
- Volunteers
- 13 people
- Sponsor
- Montecatone Rehabilitation Institute S.p.A.
Basic Physiology, Brain Stimulation
Transcranial Direct Current Stimulation (tDCS) in the Primary Motor Cortex in Healthy Individuals
The main aim of this study is to assess the short-term effects of active-tDCS (a-tDCS) on the M1 regarding sensorimotor variables such as discriminative sensation, pressure pain threshold and electromyographic activity compared…
- Trial name
- NCT04148547
- Testing
- Sooma transcranial direct current stimulation device
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Madrid
Stroke
Focal Muscle Vibration and tDCS on Motor Recovery in Stroke
Although tDCS and FV have shown some benefit as stand-alone treatment, researcher suggest that combining intervention with complementary mechanism can lead to additive or synergistic benefits which might yield more significant…
- Trial name
- NCT06893653
- Testing
- Focal muscle vibration, tDCS, Physical Therapy
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Riphah International University
Stroke
tDCS Combined With Constraint Induced Movement Therapy and Role of GABA Activity in Stroke Recovery
The aim of this study is to determine whether noninvasive brain stimulation in form of active transcranial direct current stimulation (tDCS) combined with constraint induced movement therapy (CIMT) offers an additional benefit as…
- Trial name
- NCT01983319
- Testing
- active anodal transcranial Direct Current Stimulation (tDCS), Constraint Induced Movement Therapy (CIMT)
- Where
- Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Unipolar Depression, Impulsive Behavior
How to Reduce Suicidal Thoughts and Impulsivity in Depression
The study aims at investigating if tDCS applied to left DLPFC or to right OFC to treatment as usual is effective in reducing severe suicidal ideas in major depressive episode.
- Conditions
- Unipolar Depression, Impulsive Behavior, Suicidal Ideation
- Trial name
- DEPIMPULSE (NCT05894980)
- Testing
- active tDCS stimulating left DLPFC, active tDCS stimulating right OFC
- Where
- 4 sites in France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Stroke, Cortical Excitability
Dual-task Training Combined With tDCS on Cognitive-motor Performance and Brain Activity in Stroke Patients
This study aims to evaluate the effects of tDCS combined with cognitive-motor training on dual-task interference during walking and foot pedaling, alongside corresponding alterations in brain activity assessed via fNIRS.
- Trial name
- dual-task tDCS (NCT06769672)
- Testing
- active tDCS with dual-task training
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- The Hong Kong Polytechnic University
Parkinson Disease, Cognition Disorder
The Role of EEG in Identifying Cognitive Changes in Parkinson's Disease
This study is a group controlled clinical trial. Parallel study, patients aged 40-80 years, with Parkinson disease. Twelve sessions, three times a week, for 30 minutes.
- Conditions
- Parkinson Disease, Cognition Disorder, EEG With Abnormally Slow Frequencies
- Trial name
- NCT06145776
- Testing
- tDCS + tredmill training (Standart trehab training), Cognitite-motor Dual Task Training (DT training)
- Where
- 2 sites in Brazil
- Volunteers
- 36 people
- Sponsor
- Federal University of Paraíba
Cerebrovascular Accident
Hybrid Approach to Mirror Therapy and Transcranial Direct Current Stimulation for Stroke Recovery
We hypothesize that (1) the hybrid therapy will induce greater improvements on some health-related outcomes compared to other therapies; (2) such benefits will retain at 6-month follow-up; (3) better motor control and brain…
- Trial name
- NCT02254616
- Testing
- Mirror Therapy with tDCS, Mirror Therapy, Control Intervention
- Where
- 4 sites in Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung Memorial Hospital
Healthy
Effects of Different Intensities of Bilateral- and Cathodal Transcranial Direct Current Stimulation in Healthy Individuals
This study will separate study to investigate the effects of 1 mA, 1.5 mA, and 2 mA of 1) bilateral- and 2) cathodal tDCS on cortical activity and motor learning in healthy individuals
- Trial name
- NCT05929014
- Testing
- study 1) Active bilateral-tDCS, study 2) active cathodal-tDCS
- Where
- Thailand
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Chronic Pain
Motor System Activation With Transcranial Direct Current Stimulation and Physical Exercise to Reduce Pain in Elderly
Physical exercises are known to reduce chronic pain in elderly individuals by activating the motor system. However, it seems that exercises are not effective for everyone.
- Trial name
- NCT04332939
- Testing
- transcranial direct current stimulation, Physical exercise
- Where
- 2 sites in Canada
- Volunteers
- 32 people
- Sponsor
- Université de Sherbrooke
Fibromyalgia, Electric Shock
Comparison of the Efficacy of Transcranial Direct Current Stimulation (tDCS) of the Primary Motor Cortex (M1) or the Prefrontal Cortex Combined With Aerobic Activity for Alleviation of Fibromyalgia Symptoms.
The goal of this study is to demonstrate the effectiveness of treating fibromyalgia using combination of electrical stimulation with aerobic activity. Participants will be randomly assigned to stimulation in a ratio of 1:1:1.
- Trial name
- NCT06263972
- Testing
- Direct Stimulation Prefrontal Cortex, Direct Stimulation to Motor Cortex, erobic physical activity
- Volunteers
- 120 people
- Sponsor
- HaEmek Medical Center, Israel
Chronic Pain
Chronic Pain and Transcranial Direct Current Stimulation in Clinical Settings
Physical exercises and transcranial direct current stimulation (tDCS) are both known to reduce chronic pain in structured laboratory studies.
- Trial name
- NCT04726423
- Testing
- transcranial direct current stimulation
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Université de Sherbrooke
Tinnitus
MaST: MEG and Brain Stimulation in Tinnitus
Tinnitus is the awareness of a sound in the ear or head without any outside source. It affects around 15% of people in the UK. About 20% of people with tinnitus experience symptoms that negatively affect their quality of life…
- Trial name
- MaST (NCT04978142)
- Testing
- transcranial Direct Current Stimulation (tDCS)
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Nottingham
Cognitive Ability, General
INSIGHT, A Comprehensive, Multidisciplinary Brain Training System
Adaptive reasoning and problem-solving are critical skills that allow for accurate decisions to be made based on varying levels of information.
- Trial name
- INSIGHT (NCT02780739)
- Testing
- Cognitive Training - 48 sessions, Fitness, Active Control
- Where
- United States
- Volunteers
- 521 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Urbana-Champaign
Fibromyalgia
Effect of Transcranial Direct Current Stimulation Associated With Aerobic Exercise Training for Patients With Fibromyalgia
This study consists of a randomized, double-blind, clinical trial with two months' duration of follow-up. The variable used was the VAS for pain, considering the values of any difference between the data before and after…
- Trial name
- NCT02358902
- Testing
- tDCS, active intervention of aerobic exercise
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Rheumatic Arthritis, Chronic Pain
Effect of Home-Based Transcranial Direct Current Stimulation on Pain in Patients With Rheumatoid Arthritis With Low Inflammatory Activity
Rheumatoid arthritis (RA) is a highly complex inflammatory autoimmune disease. Several drugs have been developed in recent decades to target the immune components of inflammation.
- Trial name
- tDCS RA (NCT07162311)
- Testing
- tDCS
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Fibromyalgia Syndrome
TDCS and Tele-rehabilitation Exercise in Fibromyalgia
This randomized controlled trial aims to analyze the effects of anodal tDCS applied over the primary motor cortex and dorsolateral prefrontal cortex combined with a tele-rehabilitation exercise program in patients with…
- Trial name
- NCT06616181
- Testing
- Anodal tDCS over M1, Anodal tDCS over DLPFC, Exercise telerehabilitation
- Volunteers
- 45 people
- Sponsor
- University of Valladolid
STROKE
The Immediate Effect of Electrical Stimulation Transcranial Direct Current (tDCS) Associated With the Use of FES, in Muscle Activity of the Tibialis Anterior Muscle, Balance and Plantar Pressure Distribution of Individuals With Hemiparesis Due to Stroke
Background: Transcranial direct current stimulation (tDCS) is currently considered a beneficial method for patients with neurological problems due to the modulation of cortex activity as well as the enhancement and prolongation…
- Trial name
- NCT02389608
- Testing
- Transcranial direct current stimulation (tDCS), Functional electrical stimulation (FES)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Nove de Julho
Healthy
Non-invasive Cerebellar Stimulation on Motor Learning
A crossover trial with healthy volunteers will be conducted. Six sessions will be performed once a week in a counterbalanced order and at least with seven days washout period to minimize carry-over effects.
- Trial name
- NCT02559518
- Testing
- tDCS, rTMS, pp-TMS assessment
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Cerebral Palsy
Effects of Multimodal Neuro Rehabilitation on Cortical Activity and Muscle Syenergy in Spastic Cerebral Palsy
To determine the effects of tDCS in conjunction with task-oriented training (TOT) and virtual reality (VR) as compared with sham stimulation and conventional physiotherapy on cortical activity and muscle synergy.
- Trial name
- NCT07574996
- Testing
- Active Anodal Transcranial Direct Current Stimulation (tDCS) + Task-Oriented Training, Active Anodal Transcranial Direct Current Stimulation + Virtual Reality, Conventional Physiotherapy
- Volunteers
- 150 people
- Sponsor
- Riphah International University