Clinical trials: Acute Conditions
Contraception, Pain, Acute
Empathy Through Pain Control: Buffered Compared to Unbuffered 1% Lidocaine During IUD Placement
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed.
- Conditions
- Contraception, Pain, Acute, Anesthesia, Local
- Trial name
- EPIC2 (NCT06974019)
- Testing
- Buffered Lidocaine, Lidocaine 1% Injectable Solution
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
COVID-19-Associated Encephalitis, Long COVID
Longterm Influence of Pediatric Long COVID Syndrome
We enroll pediatric patients who were diagnosed COVID-19 for main observation target. We will perform brain MRI and neuropsychiatric evaluation 4-6 months after COVID-19 diagnosed.
- Trial name
- NCT05566392
- Testing
- Brain MRI
- Where
- Taiwan
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Injury
Stories to Educate Patients With Ankle, Foot, and Knee Injuries
Study will test the use of narratives on patient satisfaction and translation of an evidence-based approach to the use of X-rays for leg injuries in the Emergency Department (ED).
- Trial name
- NCT01810523
- Testing
- Narrative, Control
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Ischemic Preconditioning
Upper Body Ischemic Preconditioning and Judo Performance
The goal of this clinical trial is to learn whether briefly stopping blood flow to the upper arms with inflatable cuffs before exercise (called ischemic preconditioning, or IPC) can improve judo-specific grip and pulling…
- Trial name
- NCT07912424
- Testing
- Upper-limb ischemic preconditioning
- Where
- Kazakhstan
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Kastamonu University
Lung Neoplasms, Respiratory Failure
Clearance Of Mucus In Stents (COMIS)
The goal of this clinical research study is to compare the effects of sodium bicarbonate to normal saline when used for clearing mucus blockage in patients with airway stents.
- Conditions
- Lung Neoplasms, Respiratory Failure, Pneumonia, Acute Coronary Syndromes
- Trial name
- NCT01370278
- Testing
- Normal Saline, Sodium Bicarbonate
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
COVID-19
Follow-up of Patients With Previous SARS-CoV-2 Infection: Long-term Damage Assessment
People affected by SARS-CoV-2 infection, whether patients have developed mild forms or a severe form of the disease, complain of nonspecific and entirely new symptoms or complain about the persistence pf them.Investigators intend…
- Trial name
- NCT05359159
- Testing
- Data collection
- Where
- 2 sites in Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of L'Aquila
Acute Pain, Respiration
Clonidine-Remifentanil. Effect of the Combination on Acute Pain and Respiration in Healthy Volunteers
The hypothesis is that systemic remifentanil and Clonidine act in a synergistic manner to relief acute main in an experimental human pain model.
- Conditions
- Acute Pain, Respiration, Sedation
- Trial name
- Remiclon (NCT00730054)
- Testing
- Remifentanil+clonidine
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Long Covid
The Effect of Acupuncture Treatment on Cognitive Functions and Brain Networks for Long COVID
Background of study: Long COVID(LC) is a prevalent sequalae of SARS-CoV-2 infection and can affect multiple organ systems. Cognitive dysfunction is one of the most common symptoms in LC with 22% prevalence.
- Trial name
- NCT07355751
- Testing
- Acupuncture
- Where
- 2 sites in China
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Tingting Luo
Biological Availability
Relative Bioavailability Study of Nirmatrelvir/Ritonavir Oral Powder Relative to the Commercial Tablets and Estimation of the Effect of Food on Bioavailability of the Nirmatrelvir/Ritonavir Oral Powder in Healthy Participants.
The purpose of this study is to estimate the relative bioavailability (rBA) of nirmatrelvir/ritonavir oral powder in 3 different food vehicles relative to the Paxlovid® tablets under fasted condition in healthy adult…
- Trial name
- NCT05544786
- Testing
- Nirmatrelvir/ ritonavir, Nirmatrelvir/Ritonavir
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Pain
Pregabalin and Remifentanil - Analgesia and Ventilation
In this experimental study on healthy volunteers we explored the effect of pregabalin alone and in combination with remifentanil on acute experimental pain and ventilatory function.
- Trial name
- NCT01419405
- Testing
- Pregabalin, Remifentanil, sugar pill, saline infusion
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Acute Pain, Anesthesia
Effectiveness of Retrolaminar Block in Lumbar Spine Fusion With Multimodal Analgesia
This randomized, blinded, controlled clinical trial aims to evaluate the effectiveness of ultrasound-guided retrolaminar block in reducing postoperative opioid consumption in patients undergoing lumbar spine fusion surgery under…
- Conditions
- Acute Pain, Anesthesia, Lumbar Spine Disease
- Trial name
- RBLUF (NCT07291388)
- Testing
- retrolaminar block
- Where
- Chile
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Myocardial Infarction, Chronic Periodontitis
The Effect of Periodontal Therapy in Chronic Periodontitis Patients With and Without Acute Myocardial Infarction
The aim of this study was to evaluate the effects of periodontal treatment on gingival crevicular fluid (GCF) levels of Neopterin(N) and vascular cell adhesion molecule (VCAM-1) in chronic periodontitis(CP) patients with acute…
- Trial name
- NCT03005886
- Testing
- Periodontal examination, GCF sampling, phase I therapy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Gazi University
Chronic Renal Insufficiency, Acute Renal Failure
Endotoxin, Neutrophil Function and Albumin in Renal Insufficiency
Chronic kidney disease is widespread in the western world with bacterial infection and sepsis as common complication. It has been shown that innate immune defence, represented by dysfunction of neutrophil granulocytes, is…
- Trial name
- ENARI (NCT01362569)
- Where
- Austria
- Volunteers
- 239 people, healthy volunteers welcome
- Sponsor
- Vanessa Stadlbauer-Koellner, MD
Obesity
Effect of High-intensity Intermittent Sprinting on Appetite Control on Obese Volunteers
Several studies have shown that high intensity intermittent sprints (HIIS) are more effective than moderate intensity continuous cycling (MICC) in reducing fat mass and improving insulin resistance in normal weight individuals.
- Trial name
- NCT01143363
- Testing
- resting - control, Moderate intensity exercise, High intensity intermittent training
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology
Thermoregulation, Sleep Disturbance
Acute Sleep Deprivation on Whole-body Heat Exchange During Exercise-heat Stress in Young and Older Men
Sleep deprivation has long been thought to modulate thermoregulatory function. Seminal work on sleep deprivation and thermoregulation has demonstrated that sleep-deprived individuals experience greater elevations in core…
- Conditions
- Thermoregulation, Sleep Disturbance, Heat Exchange, Aging
- Trial name
- NCT05838014
- Testing
- Sleep deprivation, Normal sleep
- Where
- Canada
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Long COVID, COVID-19 Pandemic
Long COVID and Its Associations With Health Outcomes in Older Adults
The Peking University Health Cohort in Anning, Yunnan (PKUHC-AN) is a prospective cohort study carried out in Anning, Yunnan. The primary aim of this study is to investigate the impact of COVID-19 on older adults' health, and to…
- Conditions
- Long COVID, COVID-19 Pandemic, Elderly Infection, Vaccine Reaction
- Trial name
- NCT05825651
- Testing
- no interventions
- Where
- China
- Volunteers
- 11,527 people, healthy volunteers welcome
- Sponsor
- Peking University
Advanced Cancer, Delirium
Delirium Recall in Advanced Cancer Patients
Primary Objectives: 1. To determine the proportion of patients who experience partial or complete recollection of symptoms of delirium and the level of distress associated with this recall. 2.
- Trial name
- NCT00493714
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Healthy
Cognitive, Emotional, and Neural Responses to Acute Inflammation
This study is a pilot study to examine the effects of acute inflammation on cognition and emotion in healthy participants using a between-subjects, randomized, double-blind design.
- Trial name
- NCT03294564
- Testing
- Typhoid Vi Polysaccharide Vaccine
- Where
- 2 sites in United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Appendicitis Acute, Appendicitis
Safety & Feasibility of PERIsign System in Demonstrating Involuntary Muscle Defense as a Sign of Peritonitis in Subjects With Appendicitis
This will be an explorative, proof-of-principle, open, multi-center investigation. The investigation aims to investigate the safety of the PERIsign system and the ability of physicians to differentiate between healthy individuals…
- Conditions
- Appendicitis Acute, Appendicitis, Abdominal Pain, Peritonitis
- Trial name
- PeriSaFe01 (NCT06296953)
- Testing
- PERIsign examination
- Where
- 2 sites in Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- STB INN AB
Chronic Obstructive Pulmonary Disease
Oral Supplement and Acute Resistance Exercise
This study should provide the mechanistic basis for and evaluation of a new nutritional formulation to be used alongside exercise training to improve muscle function and exercise performance by minimizing exercise induced…
- Trial name
- HMB exercise (NCT06801951)
- Testing
- acute resistance exercise with oral nutrition supplementation, stable tracer infusion
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
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